MiMeDB: Showing metabocard for L-Lysine (MMDBc0000059)

Read more...Show more...

Record Information

Version

1.0

Status

Detected and Quantified

Creation Date

2020-10-27 23:28:53 UTC

Update Date

2024-09-28 02:01:01 UTC

Metabolite ID

MMDBc0000059

Metabolite Identification

Common Name

L-Lysine

Description

L-lysine is an essential amino acid. Normal requirements for lysine have been found to be about 8 g per day or 12 mg/kg in adults. Children and infants need more, 44 mg/kg per day for an eleven to-twelve-year old, and 97 mg/kg per day for three-to six-month old. Lysine is highly concentrated in muscle compared to most other amino acids. Lysine is high in foods such as wheat germ, cottage cheese and chicken. Of meat products, wild game and pork have the highest concentration of lysine. Fruits and vegetables contain little lysine, except avocados. Normal lysine metabolism is dependent upon many nutrients including niacin, vitamin B6, riboflavin, vitamin C, glutamic acid and iron. Excess arginine antagonizes lysine. Several inborn errors of lysine metabolism are known, such as cystinuria, hyperdibasic aminoaciduria I, lysinuric protein intolerance, propionic acidemia, and tyrosinemia I. Most are marked by mental retardation with occasional diverse symptoms such as absence of secondary sex characteristics, undescended testes, abnormal facial structure, anemia, obesity, enlarged liver and spleen, and eye muscle imbalance. Lysine also may be a useful adjunct in the treatment of osteoporosis. Although high protein diets result in loss of large amounts of calcium in urine, so does lysine deficiency. Lysine may be an adjunct therapy because it reduces calcium losses in urine. Lysine deficiency also may result in immunodeficiency. Requirements for this amino acid are probably increased by stress. Lysine toxicity has not occurred with oral doses in humans. Lysine dosages are presently too small and may fail to reach the concentrations necessary to prove potential therapeutic applications. Lysine metabolites, amino caproic acid and carnitine have already shown their therapeutic potential. Thirty grams daily of amino caproic acid has been used as an initial daily dose in treating blood clotting disorders, indicating that the proper doses of lysine, its precursor, have yet to be used in medicine. Low lysine levels have been found in patients with Parkinson's, hypothyroidism, kidney disease, asthma and depression. The exact significance of these levels is unclear, yet lysine therapy can normalize the level and has been associated with improvement of some patients with these conditions. Abnormally elevated hydroxylysines have been found in virtually all chronic degenerative diseases and coumadin therapy. The levels of this stress marker may be improved by high doses of vitamin C. Lysine is particularly useful in therapy for marasmus (wasting) and herpes simplex. It stops the growth of herpes simplex in culture, and has helped to reduce the number and occurrence of cold sores in clinical studies. Dosing has not been adequately studied, but beneficial clinical effects occur in doses ranging from 100 mg to 4 g a day. Higher doses may also be useful, and toxicity has not been reported in doses as high as 8 g per day. Diets high in lysine and low in arginine can be useful in the prevention and treatment of herpes. Some researchers think herpes simplex virus is involved in many other diseases related to cranial nerves such as migraines, Bell's palsy and Meniere's disease. Herpes blister fluid will produce fatal encephalitis in the rabbit (http://www.dcnutrition.com).

Structure

MOL 3D MOL SDF 3D SDF PDB 3D PDB SMILES InChI

Synonyms

Value	Source
(S)-2,6-Diaminohexanoic acid	ChEBI
(S)-alpha,epsilon-Diaminocaproic acid	ChEBI
(S)-Lysine	ChEBI
6-Ammonio-L-norleucine	ChEBI
K	ChEBI
L-2,6-Diaminocaproic acid	ChEBI
L-Lysin	ChEBI
Lys	ChEBI
Lysina	ChEBI
Lysine	ChEBI
Lysine acid	ChEBI
Lysinum	ChEBI
2,6-Diaminohexanoic acid	Kegg
(S)-2,6-Diaminohexanoate	Generator
(S)-a,epsilon-Diaminocaproate	Generator
(S)-a,epsilon-Diaminocaproic acid	Generator
(S)-alpha,epsilon-Diaminocaproate	Generator
(S)-Α,epsilon-diaminocaproate	Generator
(S)-Α,epsilon-diaminocaproic acid	Generator
L-2,6-Diaminocaproate	Generator
2,6-Diaminohexanoate	Generator
(+)-S-Lysine	HMDB
(S)-2,6-Diamino-hexanoate	HMDB
(S)-2,6-Diamino-hexanoic acid	HMDB
(S)-a,e-Diaminocaproate	HMDB
(S)-a,e-Diaminocaproic acid	HMDB
6-Amino-aminutrin	HMDB
6-Amino-L-norleucine	HMDB
a-Lysine	HMDB
alpha-Lysine	HMDB
Aminutrin	HMDB
H-Lys-OH	HMDB
L-(+)-Lysine	HMDB
L-2,6-Diainohexanoate	HMDB
L-2,6-Diainohexanoic acid	HMDB
L-Lys	HMDB
Acetate, lysine	HMDB
Enisyl	HMDB
Lysine hydrochloride	HMDB
L Lysine	HMDB
Lysine acetate	HMDB

Molecular Formula

C₆H₁₄N₂O₂

Average Mass

146.1876

Monoisotopic Mass

146.105527702

IUPAC Name

(2S)-2,6-diaminohexanoic acid

Traditional Name

L-lysine

CAS Registry Number

56-87-1

SMILES

NCCCC[C@H](N)C(O)=O

InChI Identifier

InChI=1S/C6H14N2O2/c7-4-2-1-3-5(8)6(9)10/h5H,1-4,7-8H2,(H,9,10)/t5-/m0/s1

InChI Key

KDXKERNSBIXSRK-YFKPBYRVSA-N

Chemical Taxonomy

Functional Ontology

Physical Properties

Spectra

Spectrum Type	Description	Splash Key	Deposition Date	View
GC-MS	GC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (3 TMS)	splash10-00di-3910000000-98c565675de67aa87900	2014-06-16	View Spectrum
GC-MS	GC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (Non-derivatized)	splash10-0ab9-1910000000-87ef8534f592041f50f2	2014-06-16	View Spectrum
GC-MS	GC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (4 TMS)	splash10-0a4i-1921000000-84f7815b0f650fa17444	2014-06-16	View Spectrum
GC-MS	GC-MS Spectrum - GC-MS (3 TMS)	splash10-001i-9600000000-823408dba509cb204acf	2014-06-16	View Spectrum
GC-MS	GC-MS Spectrum - GC-MS (3 TMS)	splash10-00di-3910000000-4f5578af5e7d8b6c49f7	2014-06-16	View Spectrum
GC-MS	GC-MS Spectrum - GC-MS (4 TMS)	splash10-0adi-1921000000-4e56d95e623e792f9e6b	2014-06-16	View Spectrum
GC-MS	GC-MS Spectrum - EI-B (Non-derivatized)	splash10-00di-0921000000-eeb49e57bc1a75193058	2017-09-12	View Spectrum
GC-MS	GC-MS Spectrum - EI-B (Non-derivatized)	splash10-0ab9-0921000000-ebb902be0f3754225b2f	2017-09-12	View Spectrum
GC-MS	GC-MS Spectrum - GC-EI-TOF (Non-derivatized)	splash10-00di-3910000000-98c565675de67aa87900	2017-09-12	View Spectrum
GC-MS	GC-MS Spectrum - GC-EI-TOF (Non-derivatized)	splash10-0ab9-1910000000-87ef8534f592041f50f2	2017-09-12	View Spectrum
GC-MS	GC-MS Spectrum - GC-EI-QQ (Non-derivatized)	splash10-0fdk-3923000000-15b84c2649c1b0455de1	2017-09-12	View Spectrum
GC-MS	GC-MS Spectrum - GC-EI-TOF (Non-derivatized)	splash10-0a4i-1921000000-84f7815b0f650fa17444	2017-09-12	View Spectrum
GC-MS	GC-MS Spectrum - GC-MS (Non-derivatized)	splash10-001i-9600000000-823408dba509cb204acf	2017-09-12	View Spectrum
GC-MS	GC-MS Spectrum - GC-MS (Non-derivatized)	splash10-00di-3910000000-4f5578af5e7d8b6c49f7	2017-09-12	View Spectrum
GC-MS	GC-MS Spectrum - GC-MS (Non-derivatized)	splash10-0adi-1921000000-4e56d95e623e792f9e6b	2017-09-12	View Spectrum
GC-MS	GC-MS Spectrum - GC-EI-TOF (Non-derivatized)	splash10-0abi-1900000000-9ad174122e4d6e003eb8	2017-09-12	View Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive	splash10-0089-9100000000-974cc55c9130ed5213eb	2016-09-22	View Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (1 TMS) - 70eV, Positive	splash10-0ue9-9700000000-57b24ae819b6ec26bfd2	2017-10-06	View Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive	Not Available	2021-10-12	View Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (TMS_1_2) - 70eV, Positive	Not Available	2021-11-05	View Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (TMS_1_3) - 70eV, Positive	Not Available	2021-11-05	View Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (TBDMS_1_1) - 70eV, Positive	Not Available	2021-11-05	View Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (TBDMS_1_2) - 70eV, Positive	Not Available	2021-11-05	View Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (TBDMS_1_3) - 70eV, Positive	Not Available	2021-11-05	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - Quattro_QQQ 10V, Positive (Annotated)	splash10-003r-8900000000-470a0beb4f338ed89bca	2012-07-24	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - Quattro_QQQ 25V, Positive (Annotated)	splash10-001i-9000000000-74e9193d9d33c2509bfa	2012-07-24	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - Quattro_QQQ 40V, Positive (Annotated)	splash10-0a59-9000000000-822c4e78250fffa56e39	2012-07-24	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positive	splash10-0002-0900000000-04f9a62a77fb5a37ca22	2012-08-31	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positive	splash10-001i-9000000000-035035ecfa084671479b	2012-08-31	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positive	splash10-001i-0900000000-5bb15839f86f4fca0d0b	2012-08-31	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positive	splash10-001i-0900000000-6c8ef03aa83eb1cab35b	2012-08-31	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positive	splash10-01ot-0910000000-c182a7dcdbc260666978	2012-08-31	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positive	splash10-0a4j-0900000000-6c5f378cef2f14204e15	2012-08-31	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positive	splash10-001i-0900000000-41e1a6499097748934b0	2012-08-31	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positive	splash10-03di-0390000000-7270a0b85b9e3f9f6373	2012-08-31	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 10V, Negative	splash10-0002-0900000000-a997e809874357908880	2012-08-31	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 20V, Negative	splash10-0002-2900000000-f64110414f82c93e1fe8	2012-08-31	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 30V, Negative	splash10-014m-9200000000-33a38e6370811c5ddc82	2012-08-31	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 40V, Negative	splash10-0006-9000000000-3a8b0b6e62f5c66d3720	2012-08-31	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 50V, Negative	splash10-0006-9000000000-d5167570d11d77fd541e	2012-08-31	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 10V, Positive	splash10-0002-0900000000-a46231bd529176101129	2012-08-31	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 20V, Positive	splash10-001i-9200000000-f8b9f01b2a9886c51df9	2012-08-31	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 30V, Positive	splash10-001i-9000000000-ace0361476d939043e98	2012-08-31	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 40V, Positive	splash10-001i-9000000000-5b06b6e9dcf9faf8e89c	2012-08-31	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 50V, Positive	splash10-053r-9000000000-2894ef6d7f72ea71688e	2012-08-31	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - CE-ESI-TOF (CE-system connected to 6210 Time-of-Flight MS, Agilent) , Positive	splash10-0002-0900000000-290902f43cf851e8ef5e	2012-08-31	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QTOF (UPLC Q-Tof Premier, Waters) , Positive	splash10-001i-9300000000-f81193f6b50235ec8147	2012-08-31	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QTOF (UPLC Q-Tof Premier, Waters) , Positive	splash10-001i-9300000000-8931d2193adab166d5e4	2012-08-31	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QTOF (UPLC Q-Tof Premier, Waters) , Negative	splash10-0002-0900000000-b4825cc64fcb830c6967	2012-08-31	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, experimental)		2012-12-04	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 125 MHz, H₂O, experimental)		2012-12-04	View Spectrum
1D NMR	¹H NMR Spectrum (1D, D₂O, experimental)		2016-10-22	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, D₂O, predicted)		2021-09-29	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 100 MHz, D₂O, predicted)		2021-09-29	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, D₂O, predicted)		2021-09-29	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 1000 MHz, D₂O, predicted)		2021-09-29	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, D₂O, predicted)		2021-09-29	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 200 MHz, D₂O, predicted)		2021-09-29	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, D₂O, predicted)		2021-09-29	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 300 MHz, D₂O, predicted)		2021-09-29	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, D₂O, predicted)		2021-09-29	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 400 MHz, D₂O, predicted)		2021-09-29	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, D₂O, predicted)		2021-09-29	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 500 MHz, D₂O, predicted)		2021-09-29	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, D₂O, predicted)		2021-09-29	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 600 MHz, D₂O, predicted)		2021-09-29	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, D₂O, predicted)		2021-09-29	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 700 MHz, D₂O, predicted)		2021-09-29	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, D₂O, predicted)		2021-09-29	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 800 MHz, D₂O, predicted)		2021-09-29	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, D₂O, predicted)		2021-09-29	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 900 MHz, D₂O, predicted)		2021-09-29	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, experimental)		2021-10-10	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 400 MHz, H₂O, experimental)		2021-10-10	View Spectrum
2D NMR	[¹H, ¹H]-TOCSY. Unexported temporarily by An Chi on Oct 15, 2021 until json or nmrML file is generated. 2D NMR Spectrum (experimental)		2012-12-04	View Spectrum
2D NMR	[¹H, ¹³C]-HSQC NMR Spectrum (2D, 600 MHz, H₂O, experimental)		2012-12-05	View Spectrum

Biological Properties

Human Proteins and Enzymes

Protein ID	Protein Name	Protein Type	Uniprot ID	Species
MMDBp0192069	Histone-lysine N-methyltransferase, H3 lysine-79 specific	Unknown	Q8TEK3	Homo sapiens
MMDBp0192071	Histone-lysine N-methyltransferase SETD7	Unknown	Q8WTS6	Homo sapiens
MMDBp0192077	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific	Unknown	Q96L73	Homo sapiens
MMDBp0192078	Histone-lysine N-methyltransferase SETDB1	Unknown	Q15047	Homo sapiens
MMDBp0192085	Histone-lysine N-methyltransferase EHMT2	Unknown	Q96KQ7	Homo sapiens
MMDBp0192091	Histone-lysine N-methyltransferase EHMT1	Unknown	Q9H9B1	Homo sapiens
MMDBp0192119	Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1	Unknown	Q02809	Homo sapiens
MMDBp0192120	Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2	Unknown	O00469	Homo sapiens
MMDBp0192121	Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3	Unknown	O60568	Homo sapiens
MMDBp0192193	Biotinidase	Enzyme	P43251	Homo sapiens
MMDBp0192255	Lysine--tRNA ligase	Enzyme	Q15046	Homo sapiens
MMDBp0192472	Alpha-aminoadipic semialdehyde synthase, mitochondrial	Unknown	Q9UDR5	Homo sapiens
MMDBp0193306	PR domain zinc finger protein 2	Unknown	Q13029	Homo sapiens
MMDBp0193360	Histone-lysine N-methyltransferase MLL	Unknown	Q03164	Homo sapiens
MMDBp0193857	Histone-lysine N-methyltransferase MLL3	Unknown	Q8NEZ4	Homo sapiens
MMDBp0194178	Aminoadipate-semialdehyde synthase	Enzyme	A4D0W4	Homo sapiens
MMDBp0195610	Carnosine synthase 1	Unknown	A5YM72	Homo sapiens
MMDBp0195765	Histone-lysine N-methyltransferase EZH2	Unknown	Q15910	Homo sapiens
MMDBp0195771	Histone-lysine N-methyltransferase MLL2	Unknown	O14686	Homo sapiens
MMDBp0195772	Histone-lysine N-methyltransferase MLL4	Unknown	Q9UMN6	Homo sapiens
MMDBp0195774	Histone-lysine N-methyltransferase NSD2	Unknown	O96028	Homo sapiens
MMDBp0195775	Histone-lysine N-methyltransferase NSD3	Unknown	Q9BZ95	Homo sapiens
MMDBp0195787	Histone-lysine N-methyltransferase SETD2	Unknown	Q9BYW2	Homo sapiens
MMDBp0195895	Lysine-specific demethylase 2A	Enzyme	Q9Y2K7	Homo sapiens
MMDBp0195896	Lysine-specific demethylase 2B	Enzyme	Q8NHM5	Homo sapiens

Human Pathways

Metabolic Reactions

Health Effects and Bioactivity

Health Outcome/Bioactivity	Metabolite Response/Effect	Evidence Type	Host and Biospecimen	Data Source	Reference
Alzheimer's disease		Association	Human Blood	HMDB	17031479
Alzheimer's disease	Increased	Association	Human Cerebrospinal Fluid (CSF)	HMDB	17031479
Alzheimer's disease	Increased	Association	Human Saliva	HMDB	23857558
Alzheimer's disease	Slight Decrease	Association	Human Urine	HMDB	17031479
Carbamoyl phosphate synthetase deficiency		Association	Human Urine	HMDB	5471650
Cystinuria	Increased	Association	Human Urine	HMDB	14586528
Frontotemporal dementia	Increased	Association	Human Saliva	HMDB	23857558
Fumarase deficiency		Association	Human Blood	HMDB	20549362
Fumarase deficiency	Increased	Association	Human Urine	HMDB	20549362
Histidinemia		Association	Human Blood	HMDB	1481808
Hyperdibasic aminoaciduria i	Increased	Association	Human Urine	HMDB	5727921
L-2-hydroxyglutaric aciduria	Slight Increase	Association	Human Blood	HMDB	9187477
L-2-hydroxyglutaric aciduria	Slight Increase	Association	Human Urine	HMDB	9187477
L-2-hydroxyglutaric aciduria		Association	Human Cerebrospinal Fluid (CSF)	HMDB	9187477
Leukemia		Association	Human Cerebrospinal Fluid (CSF)	HMDB	15911239
Lysinuric protein intolerance	Decreased	Association	Human Blood	HMDB	27506743
Lysinuric protein intolerance	Slight Decrease	Association	Human Blood	HMDB	28028301
Lysinuric protein intolerance	Increased	Association	Human Urine	HMDB	28028301
Propionic acidemia	Increased	Association	Human Urine	HMDB	19551947
Pyruvate carboxylase deficiency		Association	Human Blood	HMDB	28649521
Refractory localization-related epilepsy	Decreased	Association	Human Blood	HMDB	14992292
Schizophrenia	Slight Increase	Association	Human Blood	HMDB	2415198
Tyrosinemia i	Increased	Association	Human Urine	HMDB	19551947
Eosinophilic esophagitis	Slight Decrease	Association	Human Urine	HMDB	Slae, M., Huynh, H., Wishart, D.S. (2014). Analysis of 30 normal pediatric urine samples via NMR spectroscopy (unpublished work)
Eosinophilic esophagitis		Association	Human Urine	HMDB	Slae, M., Huynh, H., Wishart, D.S. (2014). Analysis of 30 normal pediatric urine samples via NMR spectroscopy (unpublished work)
Lysinuric protein intolerance		Association	Human Blood	HMDB	Lysinuric Protein Intolerance and Other Cationic Aminoacidurias. The metabolic and molecular bases of inherited disease, 7/e; Editors: C.R.Scriver, A.L.Beaudet, W.S.Sly, D.Valle; McGraw-Hill Inc. (1995) DOI: 10.1036/ommbid.225
Carbamoyl phosphate synthetase deficiency	Increased	Association	Human Urine	HMDB	MetaGene: Metabolic & Genetic Information Center (MIC: http://www.metagene.de)
Carbamoyl phosphate synthetase deficiency	Increased	Association	Human Urine	HMDB	MetaGene: Metabolic & Genetic Information Center (MIC: http://www.metagene.de)

Microbial Sources

Superkingdom/Kingdom	Phylum	Total species	Hosts and Body Sites	Microbial Links
Bacteria	Firmicutes	824	Human feces; Human stool; Human ; Human urine; Human sputum; Human mucosa; Human supragingival plaque; Human saliva; Human subgingival plaque; Human pleural fluid plaque; Pig ; Cattle	Microbial culture; Indirect association between microbiota composition and metabolites measured in host biospecimen; Metabolic reconstruction
Bacteria	Proteobacteria	400	Human feces; Human stool; Human ; Human feces; pleural fluid plaque; bal; Human mucosa; Human supragingival plaque; Human saliva; Human subgingival plaque; Human sputum; Human unknown; Pig ; Human pleural fluid plaque; Human dental plaque; Human nasal swab	Microbial culture; Indirect association between microbiota composition and metabolites measured in host biospecimen; Metabolic reconstruction
Bacteria	Actinobacteria	266	Human feces; Human sputum; Human bronchial brush; Human nasopharyngeal swab; Human pleural fluid plaque; Human dental plaque; Human ; Human supragingival plaque; Human mucosa; Human subgingival plaque; Human saliva; Cattle	Microbial culture; Metabolic reconstruction
Bacteria	Fusobacteria	47	Human mucosa; Human supragingival plaque; Human ; Human urine; Human feces; Human saliva; Human subgingival plaque	Microbial culture; Metabolic reconstruction
Bacteria	Bacteroidetes	248	Human feces; Human stool; Human appendix biopsy; Human ; Human saliva; Human gastric fluid; Human urine; Human supragingival plaque; Human subgingival plaque	Microbial culture; Metabolic reconstruction
Bacteria	Verrucomicrobia	3	Human feces; Human stool; Human ; Human urine	Indirect association between microbiota composition and metabolites measured in host biospecimen; Metabolic reconstruction
Bacteria	Synergistetes	8	Human feces	Metabolic reconstruction
Bacteria	Spirochaetes	2	Human feces	Metabolic reconstruction
Archaea	Thaumarchaeota	2		Metabolic reconstruction
Archaea	Euryarchaeota	10		Metabolic reconstruction
Bacteria	Candidatus melainabacteria	2	Human feces	Metabolic reconstruction
Bacteria	Tenericutes	8	Human feces	Metabolic reconstruction
Bacteria	Planctomycetes	2	Human feces	Metabolic reconstruction
Archaea	Crenarchaeota	2		Metabolic reconstruction
Eukaryota/Fungi	Ascomycota	10	Human feces; Human saliva	Unknown
Bacteria	Aquificae	1
Archaea/Archaea	Euryarchaeota	9		Metabolic reconstruction
Bacteria	Deinococcus-thermus	1
Bacteria	nah	1
Bacteria	Thermotogae	1

Exposure Sources

Source Type	Source Sub-type	Species	Data Source	Reference
Animal	Not Available	Not Available	FooDB	34893796
Animal	Not Available	Abramis brama	FooDB	34893796
Animal	Not Available	Acipenser	FooDB	34893796
Animal	Not Available	Acipenseridae	FooDB	34893796
Animal	Not Available	African ostrich	FooDB	34893796
Animal	Not Available	Alosa sapidissima	FooDB	34893796
Animal	Not Available	Anarhichas lupus	FooDB	34893796
Animal	Not Available	Anguilla	FooDB	34893796
Animal	Not Available	Anguilliformes	FooDB	34893796
Animal	Not Available	Anoplopoma fimbria	FooDB	34893796
Animal	Not Available	Aplodinotus grunniens	FooDB	34893796
Animal	Not Available	Archosargus probatocephalus	FooDB	34893796
Animal	Not Available	Astacidea	FooDB	34893796
Animal	Not Available	Bos taurus	FooDB	34893796
Animal	Not Available	Brachyura	FooDB	34893796
Animal	Not Available	Brosme brosme	FooDB	34893796
Animal	Not Available	Buccinidae	FooDB	34893796
Animal	Not Available	Callinectes sapidus	FooDB	34893796
Animal	Not Available	Cancer magister	FooDB	34893796
Animal	Not Available	Capra aegagrus hircus	FooDB	34893796
Animal	Not Available	Catostomus commersonii	FooDB	34893796
Animal	Not Available	Chanos chanos	FooDB	34893796
Animal	Not Available	Chionoecetes opilio	FooDB	34893796
Animal	Not Available	Chondrus crispus	FooDB	Manually Annotated
Animal	Not Available	Cichlidae	FooDB	34893796
Animal	Not Available	Clupea harengus harengus	FooDB	34893796
Animal	Not Available	Clupea pallasii	FooDB	34893796
Animal	Not Available	Coregonus	FooDB	34893796
Animal	Not Available	Coregonus artedi	FooDB	34893796
Animal	Not Available	Crassostrea gigas	FooDB	34893796
Animal	Not Available	Crassostrea virginica	FooDB	34893796
Animal	Not Available	Cyprinus carpio	FooDB	34893796
Animal	Not Available	Engraulidae	FooDB	34893796
Animal	Not Available	Engraulis encrasicolus	FooDB	34893796
Animal	Not Available	Epinephelus	FooDB	34893796
Animal	Not Available	Esox lucius	FooDB	34893796
Animal	Not Available	Eucheuma	FooDB	Manually Annotated
Animal	Not Available	Gadiformes	FooDB	34893796
Animal	Not Available	Gadus	FooDB	34893796
Animal	Not Available	Gadus macrocephalus	FooDB	34893796
Animal	Not Available	Gadus morhua	FooDB	34893796
Animal	Not Available	Hippoglossus	FooDB	34893796
Animal	Not Available	Hippoglossus hippoglossus	FooDB	34893796
Animal	Not Available	Hippoglossus stenolepis	FooDB	34893796
Animal	Not Available	Homarus americanus	FooDB	34893796
Animal	Not Available	Hoplostethus atlanticus	FooDB	34893796
Animal	Not Available	Ictalurus punctatus	FooDB	34893796
Animal	Not Available	Katsuwonus pelamis	FooDB	34893796
Animal	Not Available	Laminaria	FooDB	34893796
Animal	Not Available	Lateolabrax japonicus	FooDB	34893796
Animal	Not Available	Leiostomus xanthurus	FooDB	34893796
Animal	Not Available	Lophius piscatorius	FooDB	34893796
Animal	Not Available	Lopholatilus chamaeleonticeps	FooDB	34893796
Animal	Not Available	Lota lota	FooDB	34893796
Animal	Not Available	Lutjanidae	FooDB	34893796
Animal	Not Available	Merlangius merlangus	FooDB	34893796
Animal	Not Available	Micropogonias undulatus	FooDB	34893796
Animal	Not Available	Microstomus kitt	FooDB	34893796
Animal	Not Available	Molva molva	FooDB	34893796
Animal	Not Available	Morone saxatilis	FooDB	34893796
Animal	Not Available	Mugil cephalus	FooDB	34893796
Animal	Not Available	Myoxocephalus	FooDB	Manually Annotated
Animal	Not Available	Mytilidae	FooDB	34893796
Animal	Not Available	Mytilus edulis	FooDB	34893796
Animal	Not Available	Nephropidae	FooDB	34893796
Animal	Not Available	Octopus vulgaris	FooDB	34893796
Animal	Not Available	Oncorhynchus gorbuscha	FooDB	34893796
Animal	Not Available	Oncorhynchus keta	FooDB	34893796
Animal	Not Available	Oncorhynchus kisutch	FooDB	34893796
Animal	Not Available	Oncorhynchus mykiss	FooDB	34893796
Animal	Not Available	Oncorhynchus nerka	FooDB	34893796
Animal	Not Available	Oncorhynchus tshawytscha	FooDB	34893796
Animal	Not Available	Ophiodon elongatus	FooDB	34893796
Animal	Not Available	Osmeridae	FooDB	34893796
Animal	Not Available	Osmerus mordax	FooDB	34893796
Animal	Not Available	Palinuridae	FooDB	34893796
Animal	Not Available	Paralithodes camtschaticus	FooDB	34893796
Animal	Not Available	Pectinidae	FooDB	34893796
Animal	Not Available	Peprilus triacanthus	FooDB	34893796
Animal	Not Available	Percoidei	FooDB	34893796
Animal	Not Available	Pleuronectiformes	FooDB	34893796
Animal	Not Available	Pollachius	FooDB	34893796
Animal	Not Available	Pollachius pollachius	FooDB	34893796
Animal	Not Available	Pomatomus saltatrix	FooDB	34893796
Animal	Not Available	Porphyra umbilicalis	FooDB	34893796
Animal	Not Available	Reinhardtius hippoglossoides	FooDB	34893796
Animal	Not Available	Rhodophyta	FooDB	Manually Annotated
Animal	Not Available	Saccharina japonica	FooDB	Manually Annotated
Animal	Not Available	Salmo salar	FooDB	34893796
Animal	Not Available	Salmo trutta forma trutta	FooDB	34893796
Animal	Not Available	Salmonidae	FooDB	34893796
Animal	Not Available	Scomberomorus cavalla	FooDB	34893796
Animal	Not Available	Scomberomorus maculatus	FooDB	34893796
Animal	Not Available	Scophthalmus maximus	FooDB	34893796
Animal	Not Available	Sebastes	FooDB	34893796
Animal	Not Available	Sebastes alutus	FooDB	34893796
Animal	Not Available	Sepiidae	FooDB	34893796
Animal	Not Available	Seriola lalandi	FooDB	34893796
Animal	Not Available	Siluriformes	FooDB	34893796
Animal	Not Available	Soleidae	FooDB	34893796
Animal	Not Available	Spirulina	FooDB	34893796
Animal	Not Available	Squaliformes	FooDB	34893796
Animal	Not Available	Stenodus leucichthys	FooDB	34893796
Animal	Not Available	Stenotomus chrysops	FooDB	34893796
Animal	Not Available	Strombidae	FooDB	Manually Annotated
Animal	Not Available	Sus scrofa domesticus	FooDB	34893796
Animal	Not Available	Teuthida	FooDB	34893796
Animal	Not Available	Thunnus albacares	FooDB	34893796
Animal	Not Available	Thunnus thynnus	FooDB	34893796
Animal	Not Available	Trachinotus carolinus	FooDB	34893796
Animal	Not Available	Trachurus symmetricus	FooDB	34893796
Animal	Not Available	Trisopterus esmarkii	FooDB	34893796
Animal	Not Available	Undaria pinnatifida	FooDB	34893796
Animal	Not Available	Xiphias gladius	FooDB	34893796
Animal	Not Available	Zoarces americanus	FooDB	34893796
Animal	Brain	Bos taurus	FooDB	34893796
Animal	Egg	Coregonus	FooDB	34893796
Animal	Egg	Gallus gallus	FooDB	34893796
Animal	Fat	Bos taurus	FooDB	DTU
Animal	Fat	Sus scrofa	FooDB	34893796
Animal	Heart	Bos taurus	FooDB	DTU
Animal	Kidney	Bos taurus	FooDB	DTU
Animal	Leg	Bos taurus	FooDB	34893796
Animal	Liver	Not Available	FooDB	34893796
Animal	Liver	Bos taurus	FooDB	DTU
Animal	Lung	Bos taurus	FooDB	34893796
Animal	Meat	Not Available	FooDB	34893796
Animal	Meat	African ostrich	FooDB	34893796
Animal	Meat	Bison bison	FooDB	34893796
Animal	Meat	Bos taurus	FooDB	DTU
Animal	Meat	Bubalus bubalis	FooDB	34893796
Animal	Meat	Capra aegagrus hircus	FooDB	34893796
Animal	Meat	Cervus canadensis	FooDB	34893796
Animal	Meat	Columba	FooDB	34893796
Animal	Meat	Columba livia domestica	FooDB	34893796
Animal	Meat	Dromaius novaehollandiae	FooDB	34893796
Animal	Meat	Equus caballus	FooDB	34893796
Animal	Meat	Helmeted guineafowl	FooDB	34893796
Animal	Meat	Leporidae	FooDB	34893796
Animal	Meat	Meleagris	FooDB	34893796
Animal	Meat	Phasianus colchicus	FooDB	34893796
Animal	Meat	Sus scrofa	FooDB	34893796
Animal	Meat	Sus scrofa domesticus	FooDB	34893796
Animal	Meat and skin	Not Available	FooDB	34893796
Animal	Meat and skin	Columba	FooDB	34893796
Animal	Milk	Bos taurus	FooDB	20338431
Animal	Pancreas	Bos taurus	FooDB	34893796
Animal	Rib	Bos taurus	FooDB	34893796
Animal	Roe	Not Available	FooDB	34893796
Animal	Shoulder	Bos taurus	FooDB	34893796
Animal	Skin	Sus scrofa domesticus	FooDB	34893796
Animal	Spleen	Bos taurus	FooDB	34893796
Animal	Suet	Bos taurus	FooDB	34893796
Animal	Thymus	Bos taurus	FooDB	34893796
Animal	Tongue	Bos taurus	FooDB	DTU
Food	Not Available	Not Available	FooDB	Manually Annotated
Food	Not Available	Coffea arabica	FooDB	DTU
Food	Not Available	Coffea canephora	FooDB	DTU
Food	Cocoa products	Theobroma cacao	FooDB	DTU
Plant	Not Available	Not Available	FooDB	Manually Annotated
Plant	Not Available	Abelmoschus esculentus	FooDB	34893796
Plant	Not Available	Agave	FooDB	34893796
Plant	Not Available	Allium ascalonicum	FooDB	34893796
Plant	Not Available	Allium cepa	FooDB	Manually Annotated
Plant	Not Available	Allium fistulosum	FooDB	Manually Annotated
Plant	Not Available	Allium sativum	FooDB	34893796
Plant	Not Available	Allium schoenoprasum	FooDB	34893796
Plant	Not Available	Allium tuberosum	FooDB	Manually Annotated
Plant	Not Available	Aloysia triphylla	FooDB	Manually Annotated
Plant	Not Available	Amaranthus	FooDB	34893796
Plant	Not Available	Amelanchier alnifolia	FooDB	Manually Annotated
Plant	Not Available	Anethum graveolens	FooDB	Manually Annotated
Plant	Not Available	Angelica keiskei	FooDB	Manually Annotated
Plant	Not Available	Annona cherimola	FooDB	34893796
Plant	Not Available	Apium graveolens	FooDB	34893796
Plant	Not Available	Apium graveolens var. dulce	FooDB	Manually Annotated
Plant	Not Available	Arachis hypogaea	FooDB	34893796
Plant	Not Available	Artemisia vulgaris	FooDB	Manually Annotated
Plant	Not Available	Artocarpus heterophyllus	FooDB	34893796
Plant	Not Available	Auricularia auricula-judae	FooDB	Manually Annotated
Plant	Not Available	Auricularia polytricha	FooDB	Manually Annotated
Plant	Not Available	Beta vulgaris ssp. cicla	FooDB	Manually Annotated
Plant	Not Available	Beta vulgaris var. rubra	FooDB	Manually Annotated
Plant	Not Available	Borago officinalis	FooDB	Manually Annotated
Plant	Not Available	Brassica alboglabra	FooDB	Manually Annotated
Plant	Not Available	Brassica oleracea	FooDB	34893796
Plant	Not Available	Brassica oleracea l. var. capitata l. f. alba dc.	FooDB	DTU
Plant	Not Available	Brassica oleracea var. botrytis	FooDB	34893796
Plant	Not Available	Brassica oleracea var. capitata	FooDB	34893796
Plant	Not Available	Brassica oleracea var. conica	FooDB	Manually Annotated
Plant	Not Available	Brassica oleracea var. costata	FooDB	Manually Annotated
Plant	Not Available	Brassica oleracea var. gemmifera	FooDB	34893796
Plant	Not Available	Brassica oleracea var. gongylodes	FooDB	34893796
Plant	Not Available	Brassica oleracea var. italica	FooDB	Manually Annotated
Plant	Not Available	Brassica oleracea var. sabauda	FooDB	34893796
Plant	Not Available	Brassica rapa	FooDB	34893796
Plant	Not Available	Brassica rapa var. chinensis	FooDB	34893796
Plant	Not Available	Brassica rapa var. perviridis	FooDB	Manually Annotated
Plant	Not Available	Brassica rapa var. rapa	FooDB	Manually Annotated
Plant	Not Available	Byrsonima crassifolia	FooDB	Manually Annotated
Plant	Not Available	Cantharellus cibarius	FooDB	Manually Annotated
Plant	Not Available	Capparis spinosa	FooDB	Manually Annotated
Plant	Not Available	Capsicum	FooDB	Manually Annotated
Plant	Not Available	Capsicum annuum	FooDB	Manually Annotated
Plant	Not Available	Capsicum baccatum var. baccatum	FooDB	Manually Annotated
Plant	Not Available	Capsicum chinense	FooDB	Manually Annotated
Plant	Not Available	Capsicum pubescens	FooDB	Manually Annotated
Plant	Not Available	Carica papaya	FooDB	34893796
Plant	Not Available	Carissa macrocarpa	FooDB	Manually Annotated
Plant	Not Available	Chamaemelum nobile	FooDB	Manually Annotated
Plant	Not Available	Chamerion angustifolium	FooDB	Manually Annotated
Plant	Not Available	Chenopodium album	FooDB	34893796
Plant	Not Available	Chenopodium quinoa	FooDB	34893796
Plant	Not Available	Chrysanthemum coronarium	FooDB	Manually Annotated
Plant	Not Available	Cichorium endivia	FooDB	34893796
Plant	Not Available	Cichorium intybus	FooDB	34893796
Plant	Not Available	Cichorium intybus var. foliosum	FooDB	Manually Annotated
Plant	Not Available	Cinnamomum verum	FooDB	Manually Annotated
Plant	Not Available	Cirsium	FooDB	Manually Annotated
Plant	Not Available	Citrullus lanatus var. fistulosus	FooDB	Manually Annotated
Plant	Not Available	Citrus japonica	FooDB	Manually Annotated
Plant	Not Available	Citrus maxima	FooDB	Manually Annotated
Plant	Not Available	Citrus paradisi x citrus maxima	FooDB	Manually Annotated
Plant	Not Available	Colocasia esculenta	FooDB	34893796
Plant	Not Available	Corchorus olitorius	FooDB	34893796
Plant	Not Available	Corylus avellana	FooDB	Manually Annotated
Plant	Not Available	Crateva religiosa	FooDB	Manually Annotated
Plant	Not Available	Cucumis metuliferus	FooDB	Manually Annotated
Plant	Not Available	Cucumis sativus	FooDB	Manually Annotated
Plant	Not Available	Cucurbita maxima	FooDB	Manually Annotated
Plant	Not Available	Cucurbita pepo var. clypeata	FooDB	Manually Annotated
Plant	Not Available	Cucurbita pepo var. cylindrica	FooDB	Manually Annotated
Plant	Not Available	Cuminum cyminum	FooDB	Manually Annotated
Plant	Not Available	Curcuma longa	FooDB	Manually Annotated
Plant	Not Available	Cyathea	FooDB	Manually Annotated
Plant	Not Available	Cydonia oblonga	FooDB	Manually Annotated
Plant	Not Available	Cymbopogon citratus	FooDB	Manually Annotated
Plant	Not Available	Cynara cardunculus	FooDB	Manually Annotated
Plant	Not Available	Cynara scolymus	FooDB	Manually Annotated
Plant	Not Available	Daucus carota ssp. sativus	FooDB	Manually Annotated
Plant	Not Available	Dimocarpus longan	FooDB	34893796
Plant	Not Available	Dioscorea pentaphylla	FooDB	34893796
Plant	Not Available	Durio zibethinus	FooDB	Manually Annotated
Plant	Not Available	Dysphania ambrosioides	FooDB	Manually Annotated
Plant	Not Available	Eleocharis dulcis	FooDB	Manually Annotated
Plant	Not Available	Elettaria cardamomum	FooDB	Manually Annotated
Plant	Not Available	Empetrum nigrum	FooDB	Manually Annotated
Plant	Not Available	Eragrostis tef	FooDB	34893796
Plant	Not Available	Eriobotrya japonica	FooDB	34893796
Plant	Not Available	Eruca vesicaria ssp. sativa	FooDB	Manually Annotated
Plant	Not Available	Eugenia javanica	FooDB	Manually Annotated
Plant	Not Available	Eugenia uniflora	FooDB	Manually Annotated
Plant	Not Available	Feijoa sellowiana	FooDB	34893796
Plant	Not Available	Garcinia mangostana	FooDB	Manually Annotated
Plant	Not Available	Gaylussacia baccata	FooDB	Manually Annotated
Plant	Not Available	Glycine max	FooDB	34893796
Plant	Not Available	Grataegosorbus mitschurinii	FooDB	Manually Annotated
Plant	Not Available	Grifola frondosa	FooDB	34893796
Plant	Not Available	Hedysarum alpinum	FooDB	Manually Annotated
Plant	Not Available	Hibiscus sabdariffa	FooDB	Manually Annotated
Plant	Not Available	Hippophae rhamnoides	FooDB	Manually Annotated
Plant	Not Available	Hyssopus officinalis	FooDB	Manually Annotated
Plant	Not Available	Illicium verum	FooDB	Manually Annotated
Plant	Not Available	Ipomoea aquatica	FooDB	34893796
Plant	Not Available	Ipomoea batatas	FooDB	34893796
Plant	Not Available	Juglans ailanthifolia	FooDB	Manually Annotated
Plant	Not Available	Lactuca sativa	FooDB	34893796
Plant	Not Available	Lactuca sativa l. var. longifolia	FooDB	DTU
Plant	Not Available	Lactuca sativa var. capitata	FooDB	34893796
Plant	Not Available	Lathyrus sativus	FooDB	Manually Annotated
Plant	Not Available	Laurus nobilis	FooDB	Manually Annotated
Plant	Not Available	Lens culinaris	FooDB	34893796
Plant	Not Available	Lentinus edodes	FooDB	34893796
Plant	Not Available	Levisticum officinale	FooDB	Manually Annotated
Plant	Not Available	Lippia graveolens	FooDB	Manually Annotated
Plant	Not Available	Luffa aegyptiaca	FooDB	Manually Annotated
Plant	Not Available	Lupinus	FooDB	Manually Annotated
Plant	Not Available	Macadamia tetraphylla	FooDB	Manually Annotated
Plant	Not Available	Malpighia emarginata	FooDB	Manually Annotated
Plant	Not Available	Manihot esculenta	FooDB	34893796
Plant	Not Available	Manilkara zapota	FooDB	34893796
Plant	Not Available	Matricaria recutita	FooDB	Manually Annotated
Plant	Not Available	Matteuccia struthiopteris	FooDB	Manually Annotated
Plant	Not Available	Melissa officinalis	FooDB	Manually Annotated
Plant	Not Available	Mentha	FooDB	Manually Annotated
Plant	Not Available	Mentha aquatica	FooDB	Manually Annotated
Plant	Not Available	Mentha arvensis	FooDB	Manually Annotated
Plant	Not Available	Mentha spicata	FooDB	34893796
Plant	Not Available	Mentha x piperita	FooDB	34893796
Plant	Not Available	Mespilus germanica	FooDB	Manually Annotated
Plant	Not Available	Metroxylon sagu	FooDB	Manually Annotated
Plant	Not Available	Morus	FooDB	Manually Annotated
Plant	Not Available	Morus nigra	FooDB	Manually Annotated
Plant	Not Available	Musa acuminata	FooDB	34893796
Plant	Not Available	Myrica	FooDB	Manually Annotated
Plant	Not Available	Myrica rubra	FooDB	Manually Annotated
Plant	Not Available	Nephelium lappaceum	FooDB	Manually Annotated
Plant	Not Available	Nuphar lutea	FooDB	Manually Annotated
Plant	Not Available	Ocimum basilicum	FooDB	34893796
Plant	Not Available	Opuntia	FooDB	Manually Annotated
Plant	Not Available	Opuntia cochenillifera	FooDB	34893796
Plant	Not Available	Opuntia macrorhiza	FooDB	Manually Annotated
Plant	Not Available	Origanum majorana	FooDB	Manually Annotated
Plant	Not Available	Origanum onites	FooDB	Manually Annotated
Plant	Not Available	Origanum vulgare	FooDB	34893796
Plant	Not Available	Origanum x majoricum	FooDB	Manually Annotated
Plant	Not Available	Pachyrhizus erosus	FooDB	34893796
Plant	Not Available	Panax	FooDB	Manually Annotated
Plant	Not Available	Pangium edule	FooDB	Manually Annotated
Plant	Not Available	Passiflora edulis	FooDB	Manually Annotated
Plant	Not Available	Pastinaca sativa	FooDB	Manually Annotated
Plant	Not Available	Perideridia oregana	FooDB	Manually Annotated
Plant	Not Available	Petasites japonicus	FooDB	Manually Annotated
Plant	Not Available	Petroselinum crispum	FooDB	34893796
Plant	Not Available	Phaseolus coccineus	FooDB	Manually Annotated
Plant	Not Available	Phaseolus vulgaris	FooDB	Manually Annotated
Plant	Not Available	Photinia melanocarpa	FooDB	Manually Annotated
Plant	Not Available	Physalis	FooDB	Manually Annotated
Plant	Not Available	Physalis philadelphica var. immaculata	FooDB	Manually Annotated
Plant	Not Available	Phytolacca americana	FooDB	Manually Annotated
Plant	Not Available	Pimenta dioica	FooDB	Manually Annotated
Plant	Not Available	Pimpinella anisum	FooDB	Manually Annotated
Plant	Not Available	Piper nigrum	FooDB	34893796
Plant	Not Available	Pleurotus ostreatus	FooDB	34893796
Plant	Not Available	Polygonum alpinum	FooDB	Manually Annotated
Plant	Not Available	Pouteria sapota	FooDB	34893796
Plant	Not Available	Prunus cerasus	FooDB	Manually Annotated
Plant	Not Available	Prunus persica var. persica	FooDB	Manually Annotated
Plant	Not Available	Prunus tomentosa	FooDB	Manually Annotated
Plant	Not Available	Prunus virginiana	FooDB	Manually Annotated
Plant	Not Available	Punica granatum	FooDB	Manually Annotated
Plant	Not Available	Raphanus sativus var. niger	FooDB	Manually Annotated
Plant	Not Available	Raphanus sativus var. sativus	FooDB	Manually Annotated
Plant	Not Available	Ribes aureum var. villosum	FooDB	Manually Annotated
Plant	Not Available	Ribes glandulosum	FooDB	Manually Annotated
Plant	Not Available	Ribes x nidigrolaria	FooDB	Manually Annotated
Plant	Not Available	Rorippa nasturtium-aquaticum	FooDB	34893796
Plant	Not Available	Rosmarinus officinalis	FooDB	34893796
Plant	Not Available	Rubus arcticus	FooDB	Manually Annotated
Plant	Not Available	Rubus chamaemorus	FooDB	Manually Annotated
Plant	Not Available	Rubus idaeus	FooDB	Manually Annotated
Plant	Not Available	Rubus occidentalis	FooDB	Manually Annotated
Plant	Not Available	Rubus spectabilis	FooDB	Manually Annotated
Plant	Not Available	Rubus ursinus x idaeus	FooDB	Manually Annotated
Plant	Not Available	Rubus x loganobaccus	FooDB	Manually Annotated
Plant	Not Available	Rumex	FooDB	34893796
Plant	Not Available	Rumex articus	FooDB	Manually Annotated
Plant	Not Available	Sagittaria latifolia	FooDB	Manually Annotated
Plant	Not Available	Salix pulchra	FooDB	Manually Annotated
Plant	Not Available	Salvia elegans	FooDB	Manually Annotated
Plant	Not Available	Salvia officinalis	FooDB	Manually Annotated
Plant	Not Available	Sambucus nigra	FooDB	Manually Annotated
Plant	Not Available	Satureja hortensis	FooDB	Manually Annotated
Plant	Not Available	Satureja montana	FooDB	Manually Annotated
Plant	Not Available	Scorzonera hispanica	FooDB	Manually Annotated
Plant	Not Available	Solanum lycopersicum var. cerasiforme	FooDB	Manually Annotated
Plant	Not Available	Solanum melongena	FooDB	Manually Annotated
Plant	Not Available	Solanum quitoense	FooDB	Manually Annotated
Plant	Not Available	Solanum tuberosum	FooDB	Manually Annotated
Plant	Not Available	Sorbus aucuparia	FooDB	Manually Annotated
Plant	Not Available	Spinacia oleracea	FooDB	Manually Annotated
Plant	Not Available	Syzygium cumini	FooDB	Manually Annotated
Plant	Not Available	Syzygium jambos	FooDB	Manually Annotated
Plant	Not Available	Tamarindus indica	FooDB	34893796
Plant	Not Available	Taraxacum officinale	FooDB	Manually Annotated
Plant	Not Available	Tetragonia tetragonioides	FooDB	Manually Annotated
Plant	Not Available	Thelesperma	FooDB	Manually Annotated
Plant	Not Available	Thymus pulegioides	FooDB	Manually Annotated
Plant	Not Available	Thymus vulgaris	FooDB	34893796
Plant	Not Available	Tilia	FooDB	Manually Annotated
Plant	Not Available	Tilia cordata	FooDB	Manually Annotated
Plant	Not Available	Tilia tomentosa	FooDB	Manually Annotated
Plant	Not Available	Tragopogon porrifolius	FooDB	Manually Annotated
Plant	Not Available	Typha angustifolia	FooDB	Manually Annotated
Plant	Not Available	Vaccinium alaskaense	FooDB	Manually Annotated
Plant	Not Available	Vaccinium angustifolium	FooDB	Manually Annotated
Plant	Not Available	Vaccinium angustifolium x vaccinium corymbosum	FooDB	Manually Annotated
Plant	Not Available	Vaccinium arboreum	FooDB	Manually Annotated
Plant	Not Available	Vaccinium deliciosum	FooDB	Manually Annotated
Plant	Not Available	Vaccinium elliottii	FooDB	Manually Annotated
Plant	Not Available	Vaccinium myrtilloides	FooDB	Manually Annotated
Plant	Not Available	Vaccinium ovatum	FooDB	Manually Annotated
Plant	Not Available	Vaccinium oxycoccos	FooDB	Manually Annotated
Plant	Not Available	Vaccinium parvifolium	FooDB	Manually Annotated
Plant	Not Available	Vaccinium reticulatum	FooDB	Manually Annotated
Plant	Not Available	Vaccinium stamineum	FooDB	Manually Annotated
Plant	Not Available	Vaccinium uliginosum	FooDB	Manually Annotated
Plant	Not Available	Vanilla	FooDB	Manually Annotated
Plant	Not Available	Verbena officinalis	FooDB	Manually Annotated
Plant	Not Available	Viburnum edule	FooDB	Manually Annotated
Plant	Not Available	Vigna umbellata	FooDB	Manually Annotated
Plant	Not Available	Vigna unguiculata	FooDB	Manually Annotated
Plant	Not Available	Vigna unguiculata ssp. sesquipedalis	FooDB	34893796
Plant	Not Available	Vitis aestivalis	FooDB	Manually Annotated
Plant	Not Available	Vitis labrusca	FooDB	Manually Annotated
Plant	Not Available	Vitis rotundifolia	FooDB	Manually Annotated
Plant	Not Available	Wasabia japonica	FooDB	Manually Annotated
Plant	Not Available	Xanthosoma sagittifolium	FooDB	Manually Annotated
Plant	Not Available	Ziziphus zizyphus	FooDB	Manually Annotated
Plant	Bean	Phaseolus vulgaris	FooDB	DTU
Plant	Bulb	Allium cepa	FooDB	DUKE
Plant	Bulb	Allium sativum l. var. sativum	FooDB	DUKE
Plant	Bulb	Crocus sativus	FooDB	DUKE
Plant	Bulb and lower leaf-portion	Allium ampeloprasum	FooDB	34893796
Plant	Endosperm	Cocos nucifera	FooDB	DUKE
Plant	Flour	Arachis hypogaea	FooDB	34893796
Plant	Flour	Ceratonia siliqua	FooDB	34893796
Plant	Flour	Glycine max	FooDB	34893796
Plant	Flour	Maranta arundinacea	FooDB	34893796
Plant	Flower	Sesbania bispinosa	FooDB	34893796
Plant	Fruit	Not Available	FooDB	34893796
Plant	Fruit	Abelmoschus esculentus	FooDB	DUKE
Plant	Fruit	Actinidia chinensis	FooDB	34893796
Plant	Fruit	Ananas comosus	FooDB	DUKE
Plant	Fruit	Annona muricata	FooDB	DUKE
Plant	Fruit	Annona reticulata	FooDB	DUKE
Plant	Fruit	Annona squamosa	FooDB	DUKE
Plant	Fruit	Artocarpus altilis	FooDB	DUKE
Plant	Fruit	Averrhoa carambola	FooDB	DUKE
Plant	Fruit	Benincasa hispida	FooDB	DUKE
Plant	Fruit	Capsicum annuum	FooDB	All-Creatures
Plant	Fruit	Capsicum annuum var. annuum	FooDB	DUKE
Plant	Fruit	Carica papaya	FooDB	DUKE
Plant	Fruit	Citrullus lanatus	FooDB	DUKE
Plant	Fruit	Citrus aurantiifolia	FooDB	DUKE
Plant	Fruit	Citrus latifolia	FooDB	34893796
Plant	Fruit	Citrus paradisi x citrus maxima	FooDB	34893796
Plant	Fruit	Citrus reticulata	FooDB	DUKE
Plant	Fruit	Citrus sinensis	FooDB	DUKE
Plant	Fruit	Citrus x paradisi	FooDB	34893796
Plant	Fruit	Coriandrum sativum	FooDB	DUKE
Plant	Fruit	Cucumis melo var. cantalupensis	FooDB	34893796
Plant	Fruit	Cucumis sativus	FooDB	DUKE
Plant	Fruit	Cucurbita	FooDB	DUKE
Plant	Fruit	Cucurbita maxima	FooDB	DTU
Plant	Fruit	Cucurbita moschata	FooDB	34893796
Plant	Fruit	Cucurbita pepo var. clypeata	FooDB	DTU
Plant	Fruit	Cucurbita pepo var. cylindrica	FooDB	DTU
Plant	Fruit	Cucurbita pepo var. turbinata	FooDB	34893796
Plant	Fruit	Diospyros	FooDB	34893796
Plant	Fruit	Diospyros kaki	FooDB	34893796
Plant	Fruit	Diospyros virginiana	FooDB	34893796
Plant	Fruit	Ficus carica	FooDB	DUKE
Plant	Fruit	Lagenaria siceraria	FooDB	DUKE
Plant	Fruit	Lentinus edodes	FooDB	DUKE
Plant	Fruit	Lycium barbarum	FooDB	34893796
Plant	Fruit	Malus pumila	FooDB	DUKE
Plant	Fruit	Mangifera indica	FooDB	DUKE
Plant	Fruit	Musa x paradisiaca	FooDB	DUKE
Plant	Fruit	Persea americana	FooDB	DUKE
Plant	Fruit	Phaseolus vulgaris	FooDB	DUKE
Plant	Fruit	Phoenix dactylifera	FooDB	DUKE
Plant	Fruit	Pisum sativum	FooDB	DUKE
Plant	Fruit	Prunus armeniaca	FooDB	DUKE
Plant	Fruit	Prunus domestica	FooDB	DUKE
Plant	Fruit	Prunus persica	FooDB	DUKE
Plant	Fruit	Prunus persica var. nucipersica	FooDB	34893796
Plant	Fruit	Prunus persica var. persica	FooDB	34893796
Plant	Fruit	Psidium cattleianum	FooDB	DUKE
Plant	Fruit	Psidium guajava	FooDB	DUKE
Plant	Fruit	Pyrus communis	FooDB	DUKE
Plant	Fruit	Pyrus pyrifolia	FooDB	34893796
Plant	Fruit	Sechium edule	FooDB	DUKE
Plant	Fruit	Siraitia grosvenorii	FooDB	34893796
Plant	Fruit	Solanum lycopersicum var. lycopersicum	FooDB	DUKE
Plant	Fruit	Solanum melongena	FooDB	DUKE
Plant	Fruit	Tamarindus indica	FooDB	DUKE
Plant	Fruit	Vaccinium corymbosum	FooDB	DUKE
Plant	Fruit	Vigna unguiculata ssp. sesquipedalis	FooDB	DUKE
Plant	Fruit	Vitis	FooDB	34893796
Plant	Fruit	Vitis vinifera	FooDB	DUKE
Plant	Ground	Cinnamomum	FooDB	34893796
Plant	Ground	Curcuma longa	FooDB	34893796
Plant	Ground	Syzygium aromaticum	FooDB	34893796
Plant	Herb	Portulaca oleracea	FooDB	DUKE
Plant	Herb	Rorippa nasturtium-aquaticum	FooDB	DUKE
Plant	Leaves	Not Available	FooDB	DTU
Plant	Leaves	Allium schoenoprasum	FooDB	DUKE
Plant	Leaves	Amaranthus	FooDB	DUKE
Plant	Leaves	Artemisia dracunculus	FooDB	DUKE
Plant	Leaves	Basella alba	FooDB	DUKE
Plant	Leaves	Brassica oleracea l. var. capitata l. f. alba dc.	FooDB	DUKE
Plant	Leaves	Brassica oleracea var. capitata	FooDB	DUKE
Plant	Leaves	Brassica oleracea var. gemmifera	FooDB	DUKE
Plant	Leaves	Brassica oleracea var. italica	FooDB	DUKE
Plant	Leaves	Camellia sinensis	FooDB	DTU
Plant	Leaves	Cichorium endivia	FooDB	DUKE
Plant	Leaves	Cichorium intybus	FooDB	DUKE
Plant	Leaves	Colocasia esculenta	FooDB	DUKE
Plant	Leaves	Corchorus olitorius	FooDB	DUKE
Plant	Leaves	Lactuca sativa	FooDB	DUKE
Plant	Leaves	Mentha spicata	FooDB	DUKE
Plant	Leaves	Mentha x piperita	FooDB	DUKE
Plant	Leaves	Ocimum basilicum	FooDB	DUKE
Plant	Leaves	Psophocarpus tetragonolobus	FooDB	DUKE
Plant	Leaves	Rosmarinus officinalis	FooDB	DUKE
Plant	Leaves	Spinacia oleracea	FooDB	DUKE
Plant	Leaves	Trigonella foenum-graecum	FooDB	DUKE
Plant	Nut	Canarium ovatum	FooDB	34893796
Plant	Nut	Carya	FooDB	34893796
Plant	Nut	Carya illinoinensis	FooDB	34893796
Plant	Nut	Castanea	FooDB	34893796
Plant	Nut	Castanea crenata	FooDB	34893796
Plant	Nut	Castanea mollissima	FooDB	34893796
Plant	Nut	Castanea sativa	FooDB	34893796
Plant	Nut	Cocos nucifera	FooDB	34893796
Plant	Nut	Corylus	FooDB	34893796
Plant	Nut	Corylus avellana	FooDB	34893796
Plant	Nut	Fagus	FooDB	34893796
Plant	Nut	Ginkgo biloba	FooDB	34893796
Plant	Nut	Juglans	FooDB	34893796
Plant	Nut	Juglans cinerea	FooDB	34893796
Plant	Nut	Juglans nigra	FooDB	34893796
Plant	Nut	Juglans regia	FooDB	34893796
Plant	Nut	Macadamia	FooDB	34893796
Plant	Nut	Macadamia tetraphylla	FooDB	34893796
Plant	Nut	Pinus	FooDB	34893796
Plant	Nut	Pinus edulis	FooDB	34893796
Plant	Nut	Pistacia vera	FooDB	34893796
Plant	Nut	Prunus dulcis	FooDB	34893796
Plant	Nut	Quercus	FooDB	34893796
Plant	Oil	Not Available	FooDB	34893796
Plant	Oil	Elaeis	FooDB	34893796
Plant	Oil	Virola surinamensis	FooDB	34893796
Plant	Plant	Allium ampeloprasum	FooDB	DUKE
Plant	Plant	Linum usitatissimum	FooDB	DUKE
Plant	Plant	Petroselinum crispum	FooDB	DUKE
Plant	Plant	Spinacia oleracea	FooDB	DUKE
Plant	Plant	Thymus vulgaris	FooDB	DUKE
Plant	Plant	Valerianella locusta	FooDB	DUKE
Plant	Rhizome	Nelumbo nucifera	FooDB	DUKE
Plant	Root	Arctium lappa	FooDB	DUKE
Plant	Root	Beta vulgaris	FooDB	34893796
Plant	Root	Beta vulgaris var. rubra	FooDB	DUKE
Plant	Root	Colocasia esculenta	FooDB	DUKE
Plant	Root	Daucus carota	FooDB	DUKE
Plant	Root	Daucus carota ssp. sativus	FooDB	DUKE
Plant	Root	Dioscorea pentaphylla	FooDB	DUKE
Plant	Root	Ipomoea batatas	FooDB	DUKE
Plant	Root	Manihot esculenta	FooDB	DUKE
Plant	Root	Nelumbo	FooDB	34893796
Plant	Root	Pediomelum esculentum	FooDB	DUKE
Plant	Root	Raphanus sativus	FooDB	DUKE
Plant	Root	Raphanus sativus var. longipinnatus	FooDB	34893796
Plant	Root	Zingiber officinale	FooDB	DUKE
Plant	Seed	Not Available	FooDB	34893796
Plant	Seed	Amaranthus	FooDB	34893796
Plant	Seed	Anacardium occidentale	FooDB	DUKE
Plant	Seed	Anethum graveolens	FooDB	DUKE
Plant	Seed	Arachis hypogaea	FooDB	DUKE
Plant	Seed	Artocarpus altilis	FooDB	DUKE
Plant	Seed	Bertholletia excelsa	FooDB	DUKE
Plant	Seed	Brosimum alicastrum	FooDB	34893796
Plant	Seed	Cajanus cajan	FooDB	DUKE
Plant	Seed	Carum carvi	FooDB	DUKE
Plant	Seed	Castanea sativa	FooDB	DUKE
Plant	Seed	Ceratonia siliqua	FooDB	DUKE
Plant	Seed	Chenopodium album	FooDB	DUKE
Plant	Seed	Cicer arietinum	FooDB	DUKE
Plant	Seed	Citrullus lanatus	FooDB	DUKE
Plant	Seed	Cucurbita maxima	FooDB	34893796
Plant	Seed	Cucurbita pepo var. clypeata	FooDB	34893796
Plant	Seed	Ginkgo biloba	FooDB	DUKE
Plant	Seed	Glycine max	FooDB	DUKE
Plant	Seed	Gossypium	FooDB	34893796
Plant	Seed	Helianthus annuus	FooDB	DUKE
Plant	Seed	Juglans cinerea	FooDB	DUKE
Plant	Seed	Juglans nigra	FooDB	DUKE
Plant	Seed	Juglans regia	FooDB	DUKE
Plant	Seed	Lablab purpureus	FooDB	DUKE
Plant	Seed	Lens culinaris	FooDB	DUKE
Plant	Seed	Linum usitatissimum	FooDB	34893796
Plant	Seed	Lupinus	FooDB	34893796
Plant	Seed	Lupinus albus	FooDB	DUKE
Plant	Seed	Macadamia	FooDB	DUKE
Plant	Seed	Momordica charantia	FooDB	DUKE
Plant	Seed	Nelumbo nucifera	FooDB	DUKE
Plant	Seed	Oenothera biennis	FooDB	DUKE
Plant	Seed	Phaseolus lunatus	FooDB	DUKE
Plant	Seed	Phaseolus vulgaris	FooDB	DUKE
Plant	Seed	Pinus edulis	FooDB	DUKE
Plant	Seed	Pistacia vera	FooDB	DUKE
Plant	Seed	Pisum sativum	FooDB	DUKE
Plant	Seed	Prunus dulcis	FooDB	DUKE
Plant	Seed	Psophocarpus tetragonolobus	FooDB	DUKE
Plant	Seed	Salvia hispanica	FooDB	34893796
Plant	Seed	Sesamum orientale	FooDB	DUKE
Plant	Seed	Sinapis alba	FooDB	DUKE
Plant	Seed	Theobroma cacao	FooDB	DUKE
Plant	Seed	Trigonella foenum-graecum	FooDB	DUKE
Plant	Seed	Vicia faba	FooDB	DUKE
Plant	Seed	Vigna aconitifolia	FooDB	DUKE
Plant	Seed	Vigna angularis	FooDB	DUKE
Plant	Seed	Vigna mungo	FooDB	34893796
Plant	Seed	Vigna radiata	FooDB	DUKE
Plant	Seed	Vigna unguiculata	FooDB	34893796
Plant	Seed	Vigna unguiculata ssp. cylindrica	FooDB	34893796
Plant	Seed	Vigna unguiculata ssp. sesquipedalis	FooDB	DUKE
Plant	Seed	Vigna unguiculata ssp. unguiculata	FooDB	DUKE
Plant	Shoot	Asparagus officinalis	FooDB	DUKE
Plant	Shoot	Moringa oleifera	FooDB	DUKE
Plant	Shoot	Phyllostachys edulis	FooDB	34893796
Plant	Sprout seedling	Lens culinaris	FooDB	DUKE
Plant	Sprout seedling	Phaseolus vulgaris	FooDB	DUKE
Plant	Sprout seedling	Vigna radiata	FooDB	DUKE
Plant	Stem	Brassica oleracea var. gongylodes	FooDB	DUKE
Plant	Tuber	Dioscorea	FooDB	34893796
Plant	Tuber	Helianthus tuberosus	FooDB	DUKE
Plant	Tuber	Pachyrhizus erosus	FooDB	DUKE
Plant	Tuber	Psophocarpus tetragonolobus	FooDB	DUKE
Plant	Tuber	Solanum tuberosum	FooDB	DUKE

Host Biospecimen and Location

Host and Biospecimen	Status	Mean	Std	Min	Max	Units	Age	Sex	Health Condition	Data Source	Reference
Human Feces	Detected but not Quantified									HMDB
Human Cerebrospinal fluid (csf)	Detected and Quantified	226				uM	Infant (0-1 year old)	Male	2,4-dienoyl-CoA reductase deficiency	HMDB	24847004
Human Urine	Detected and Quantified	1779				umol/mmol creatinine	Infant (0-1 year old)	Male	2,4-dienoyl-CoA reductase deficiency	HMDB	24847004
Human Blood	Detected and Quantified			135	831	uM	Infant (0-1 year old)	Male	2,4-dienoyl-CoA reductase deficiency	HMDB	24847004
Human Urine	Detected and Quantified	3.414				umol/mmol creatinine	Children (1-13 years old)	Male	Alpha-aminoadipic and alpha-ketoadipic aciduria	HMDB	8487492
Human Blood	Detected and Quantified	82.9				uM	Children (1-13 years old)	Male	Alpha-aminoadipic and alpha-ketoadipic aciduria	HMDB	8487492
Human Blood	Detected and Quantified	216.7	54.5			uM	Elderly (>65 years old)	Both	Alzheimer's disease	HMDB	17031479
Human Cerebrospinal fluid (csf)	Detected and Quantified	44.6	10.8			uM	Adult (>18 years old)	Both	Alzheimer's disease	HMDB	17031479
Human Saliva	Detected and Quantified	45.55	15.63			uM	Adult (>18 years old)	Male	Alzheimer's disease	HMDB	23857558
Human Urine	Detected and Quantified	5.5	1.74			umol/mmol creatinine	Adult (>18 years old)	Both	Alzheimer's disease	HMDB	17031479
Human Urine	Detected and Quantified			0.0039	0.0116	umol/mmol creatinine	Adult (>18 years old)	Both	ADPKD	HMDB	21389975
Human Urine	Detected and Quantified			1.0489	5.518	umol/mmol creatinine	Infant (0-1 year old)	Female	Carbamoyl Phosphate Synthetase Deficiency	HMDB	5471650
Human Blood	Detected and Quantified			220	384	uM	Newborn (0-30 days old)	Both	Citrullinemia type II, neonatal-onset	HMDB	11281457
Human Urine	Detected and Quantified	1272.2				umol/mmol creatinine	Adult (>18 years old)	Both	Cystinuria	HMDB	14586528
Human Urine	Detected and Quantified			130.200	1873.600	umol/mmol creatinine	Adult (>18 years old)	Both	Cystinuria	HMDB	14586528
Human Saliva	Detected and Quantified	41.71	22.55			uM	Adult (>18 years old)	Male	Frontotemporal lobe dementia	HMDB	23857558
Human Blood	Detected and Quantified	107				uM	Infant (0-1 year old)	Male	Fumaric aciduria	HMDB	20549362
Human Urine	Detected and Quantified			268.300	365.200	umol/mmol creatinine	Infant (0-1 year old)	Not Specified	Fumaric aciduria	HMDB	20549362
Human Blood	Detected and Quantified	147	42			uM	Children (1 - 13 years old)	Male	Histidinuria	HMDB	1481808
Human Urine	Detected and Quantified			111.677	220.880	umol/mmol creatinine	Children (1 - 13 years old)	Female	Hyperdibasic aminoaciduria I	HMDB	5727921
Human Urine	Detected and Quantified			30.704	137.431	umol/mmol creatinine	Adult (>18 years old)	Both	Hyperdibasic aminoaciduria I	HMDB	5727921
Human Urine	Detected and Quantified			30.704	356.533	umol/mmol creatinine	Adult (>18 years old)	Both	Dibasic Amino Aciduria I	HMDB	5727921
Human Urine	Detected and Quantified			41.840	220.880	umol/mmol creatinine	Children (1-13 years old)	Female	Dibasic Amino Aciduria I	HMDB	5727921
Human Blood	Detected and Quantified			1208	1472	uM	Children (1-13 years old)	Both	Hyperlysinemia I, familial	HMDB	23890588
Human Urine	Detected and Quantified			1384	1742	umol/mmol creatinine	Children (1-13 years old)	Both	Hyperlysinemia I, familial	HMDB	23890588
Human Urine	Detected and Quantified	1413.757				umol/mmol creatinine	Children (1-13 years old)	Female	Hyperlysinuria	HMDB	1246485
Human Urine	Detected and Quantified			2050	18736	umol/mmol creatinine	Adult (>18 years old)	Both	Hyperlysinuria	HMDB	14586528
Human Blood	Detected and Quantified			185	396	uM	Children (1-13 years old)	Both	L-2-hydroxyglutaric aciduria	HMDB	9187477
Human Urine	Detected and Quantified			36	168	umol/mmol creatinine	Children (1-13 years old)	Both	L-2-hydroxyglutaric aciduria	HMDB	9187477
Human Cerebrospinal fluid (csf)	Detected and Quantified			60.000	94.500	uM	Children (1-13 years old)	Female	L-2-hydroxyglutaric aciduria	HMDB	9187477
Human Cerebrospinal fluid (csf)	Detected and Quantified	21.9	6.2			uM	Children (1-13 years old)	Not Specified	Leukemia	HMDB	15911239
Human Cerebrospinal fluid (csf)	Detected and Quantified	26.9	11.1			uM	Children (1-13 years old)	Not Specified	Leukemia	HMDB	15911239
Human Saliva	Detected and Quantified	37.38	19.11			uM	Adult (>18 years old)	Both	Lewy body disease	HMDB	23857558
Human Blood	Detected and Quantified	180.5		142	326	uM	Children (1-13 years old)	Male	Lipoyltransferase 1 Deficiency	HMDB	24341803
Human Blood	Detected and Quantified	116		89.4	136	uM	Adult (>18 years old)	Both	Lysinuric protein intolerance	HMDB	27506743
Human Blood	Detected and Quantified			24	73	uM	Children (1 - 13 years old)	Both	Lysinuric protein intolerance	HMDB	28028301
Human Urine	Detected and Quantified			548	1317.200	umol/mmol creatinine	Children (1 - 13 years old)	Both	Lysinuric protein intolerance	HMDB	28028301
Human Blood	Detected and Quantified	97.44	29.48			uM	Adult (>18 years old)	Female	Pregnancy	HMDB	24704061
Human Urine	Detected and Quantified	101	13			umol/mmol creatinine	Adult (>18 years old)	Both	Propionic acidemia	HMDB	19551947
Human Blood	Detected and Quantified	136				uM	Children (1-13 years old)		Pyruvate carboxylase deficiency	HMDB	28649521
Human Blood	Detected and Quantified	713				uM	Infant (0-1 year old)		Pyruvate carboxylase deficiency	HMDB	28649521
Human Blood	Detected and Quantified	128.0	9.0			uM	Adult (>18 years old)	Both	Refractory localization-related epilepsy (RLE)	HMDB	14992292
Human Blood	Detected and Quantified	186	28			uM	Adult (>18 years old)	Female	Schizophrenia	HMDB	2415198
Human Blood	Detected and Quantified	206	29			uM	Adult (>18 years old)	Male	Schizophrenia	HMDB	2415198
Human Urine	Detected and Quantified	321.8	15.4			umol/mmol creatinine	Adult (>18 years old)	Both	Tyrosinemia I	HMDB	19551947
Human Urine	Detected and Quantified	452.1	60.2			umol/mmol creatinine	Adult (>18 years old)	Both	Tyrosinemia I	HMDB	19551947
Human Urine	Detected and Quantified	4.7				umol/mmol creatinine	Adult (>18 years old)	Both	Normal	HMDB	21388201
Human Cerebrospinal fluid (csf)	Detected and Quantified			10	28	uM	Children (1-13 years old)	Both	Normal	HMDB	23890588
Human Sweat	Detected and Quantified	< 10				uM	Adult (60 years old)	Male	Normal	HMDB	22194922
Human Sweat	Detected and Quantified	< 10				uM	Adult (40 years old)	Male	Normal	HMDB	22194922
Human Saliva	Detected and Quantified	>10				uM	Adult (>18 years old)	Both	Normal	HMDB	12097436
Human Urine	Detected and Quantified			0	69	umol/mmol creatinine	Children (1-13 years old)	Both	Normal	HMDB	23890588
Human Urine	Detected and Quantified			1.32	26.75	umol/mmol creatinine	Newborn (0-30 days old)	Male	Normal	HMDB	25536744
Human Urine	Detected and Quantified	1.933	1.0741			umol/mmol creatinine	Not Specified	Not Specified	Normal	HMDB	8487492
Human Urine	Detected and Quantified			10	68	umol/mmol creatinine	Children (1 - 13 years old)	Both	Normal	HMDB	28028301
Human Urine	Detected and Quantified	10.28	5.34			umol/mmol creatinine	Adult (>18 years old)	Both	Normal	HMDB	15992788
Human Urine	Detected and Quantified			10.5	140.5	umol/mmol creatinine	Newborn (0-30 days old)	Both	Normal	HMDB	32340350
Human Urine	Detected and Quantified	10.87	8.80			umol/mmol creatinine	Newborn (0-30 days old)	Male	Normal	HMDB	25536744
Human Blood	Detected and Quantified	105.100	30.100			uM	Not Specified	Not Specified	Normal	HMDB	8487492
Human Breast milk	Detected and Quantified	11.1	8.8			uM	Adult (>18 years old)	Female	Normal	HMDB	24027187
Human Urine	Detected and Quantified	11.601	3.867			umol/mmol creatinine	Adult (>18 years old)	Not Specified	Normal	HMDB	5727921
Human Urine	Detected and Quantified	11.601	3.867			umol/mmol creatinine	Not Specified	Not Specified	Normal	HMDB	5727921
Human Blood	Detected and Quantified			112	231	uM	Children (1-13 years old)	Both	Normal	HMDB	23890588
Human Blood	Detected and Quantified			113	269	uM	Infant (0-1 year old)	Not Specified	Normal	HMDB	24341803
Human Blood	Detected and Quantified			120	203	uM	Newborn (0-30 days old)	Not Specified	Normal	HMDB	11281457
Human Blood	Detected and Quantified	127.8		108.8	147.7	uM	Children (1-13 uears old)	Both	Normal	HMDB	27294788
Human Urine	Detected and Quantified	13.09	5.90			umol/mmol creatinine	Children (0-2 years old)	Male	Normal	HMDB	25536744
Human Urine	Detected and Quantified	13.44	5.50			umol/mmol creatinine	Children (0-2 years old)	Male	Normal	HMDB	25536744
Human Cerebrospinal fluid (csf)	Detected and Quantified			14.100	25.300	uM	Not Specified	Not Specified	Normal	HMDB	9187477
Human Urine	Detected and Quantified	16.06	7.48			umol/mmol creatinine	Newborn (0-30 days old)	Female	Normal	HMDB	25536744
Human Blood	Detected and Quantified	161	21			uM	Adult (>18 years old)	Female	Normal	HMDB	2415198
Human Urine	Detected and Quantified	17.2		3.7	51.3	umol/mmol creatinine	Adult (>18 years old)	Both	Normal	HMDB	24023812
Human Urine	Detected and Quantified	17.9		3.6	56.1	umol/mmol creatinine	Adult (>18 years old)	Both	Normal	HMDB	24023812
Human Blood	Detected and Quantified	178.6	58.2			uM	Adult (>18 years old)	Both	Normal	HMDB	21359215
Human Blood	Detected and Quantified	188.0		156.0	220.0	uM	Adult (>18 years old)	Both	Normal	HMDB	12297216
Human Blood	Detected and Quantified	189	27			uM	Adult (>18 years old)	Male	Normal	HMDB	2415198
Human Urine	Detected and Quantified			19.335	100.541	umol/mmol creatinine	Children (1-13 years old)	Not Specified	Normal	HMDB	1246485
Human Blood	Detected and Quantified	197		184	216	uM	Adult (>18 years old)	Both	Normal	HMDB	27506743
Human Blood	Detected and Quantified	197.4	30.7			uM	Adult (>18 years old)	Both	Normal	HMDB	28278231
Human Saliva	Detected and Quantified	2.2	3.8			uM	Adult (>18 years old)	Male	Normal	HMDB	21164041
Human Urine	Detected and Quantified	226.12	158.28			umol/mmol creatinine	Newborn (0-30 days old)	Both	Normal	HMDB	19468821
Human Cerebrospinal fluid (csf)	Detected and Quantified	23.9		18.1	29.7	uM	Adult (>18 years old)	Both	Normal	HMDB	12834252
Human Blood	Detected and Quantified	238		192	295	uM	Infant (0-1 year old)		Normal	HMDB	25754623
Human Urine	Detected and Quantified			24.647	202.943	umol/mmol creatinine	Infant (0-1 year old)	Not Specified	Normal	HMDB	20549362
Human Cerebrospinal fluid (csf)	Detected and Quantified	25.7	5.3			uM	Adult (>18 years old)	Not Specified	Normal	HMDB	6198473
Human Cerebrospinal fluid (csf)	Detected and Quantified	27.7	8.0			uM	Adult (>18 years old)	Not Specified	Normal	HMDB	15911239
Human Cerebrospinal fluid (csf)	Detected and Quantified	29.0	13.0			uM	Not Specified	Both	Normal	HMDB	18953024
Human Feces	Detected and Quantified	2964.228		1664.528	4263.928	nmol/g wet feces	Infant (0-1 year old)	Not Specified	Normal	HMDB	22435727
Human Urine	Detected and Quantified			3	170	umol/mmol creatinine	Infant (0-1 year old)	Both	Normal	HMDB	30830347
Human Urine	Detected and Quantified			3	170	umol/mmol creatinine	Newborn (0-30 days old)	Both	Normal	HMDB	30830347
Human Urine	Detected and Quantified	3.1	1.5			umol/mmol creatinine	Infant (1 - 6 months old)	Both	Normal	HMDB	3168222
Human Urine	Detected and Quantified	3.2	1.9			umol/mmol creatinine	Infant (6 months - <1 year old)	Both	Normal	HMDB	3168222
Human Saliva	Detected and Quantified	3.7	6.3			uM	Adult (>18 years old)	Male	Normal	HMDB	21164041
Human Feces	Detected and Quantified	3078.236		2052.158	4104.315	nmol/g wet feces	Infant (0-1 year old)	Not Specified	Normal	HMDB	22435727
Human Urine	Detected and Quantified	31.45	52.32			umol/mmol creatinine	Infant (0-1 year old)	Both	Normal	HMDB	2026685
Human Cerebrospinal fluid (csf)	Detected and Quantified	31.5	5.7			uM	Adult (>18 years old)	Not Specified	Normal	HMDB	6198473
Human Urine	Detected and Quantified	38.05	15.47			umol/mmol creatinine	Newborn (0-30 days old)	Female	Normal	HMDB	32340350
Human Urine	Detected and Quantified			4.4 +	1.6	umol/mmol creatinine	Newborn (0-30 days old)	Both	Normal	HMDB	3168222
Human Feces	Detected and Quantified	40	30			nmol/g wet feces	Adult (>18 years old)	Both	Normal	HMDB	27624970
Human Blood	Detected and Quantified			40	163	uM	Not Specified	Not Specified	Normal	HMDB	9187477
Human Urine	Detected and Quantified	407.02	260.04			umol/mmol creatinine	Newborn (0-30 days old)	Both	Normal	HMDB	19468821
Human Blood	Detected and Quantified	434.0	23.0			uM	Adult (>18 years old)	Both	Normal	HMDB	16789974
Human Blood	Detected and Quantified	441		384	516	uM	Newborn (0-30 days old)		Normal	HMDB	25754623
Human Feces	Detected and Quantified	4697.161		1983.752	7410.569	nmol/g wet feces	Infant (0-1 year old)	Not Specified	Normal	HMDB	22435727
Human Urine	Detected and Quantified			5.2	16	umol/mmol creatinine	Adult (>18 years old)	Female	Normal	HMDB	27012787
Human Urine	Detected and Quantified			5.6	15	umol/mmol creatinine	Adult (>18 years old)	Male	Normal	HMDB	27012787
Human Urine	Detected and Quantified	51.37	33.33			umol/mmol creatinine	Newborn (0-30 days old)	Male	Normal	HMDB	32340350
Human Urine	Detected and Quantified	520.08	327.87			umol/mmol creatinine	Newborn (0-30 days old)	Both	Normal	HMDB	19468821
Human Feces	Detected and Quantified	540	410			nmol/g wet feces	Adult (>18 years old)	Both	Normal	HMDB	27624970
Human Blood	Detected and Quantified			56	256	uM	Children (1 - 13 years old)	Both	Normal	HMDB	28028301
Human Saliva	Detected and Quantified	59.20	46.76			uM	Adult (>18 years old)	Female	Normal	HMDB	23857558
Human Urine	Detected and Quantified			7	58	umol/mmol creatinine	Not Specified	Not Specified	Normal	HMDB	9187477
Human Urine	Detected and Quantified			7.70	30.13	umol/mmol creatinine	Newborn (0-30 days old)	Female	Normal	HMDB	25536744
Human Blood	Detected and Quantified			82	224	uM	Children (1 - 13 years old)	Not Specified	Normal	HMDB	1481808
Human Blood	Detected and Quantified			85	241	uM	Children (1-13 years old)	Not Specified	Normal	HMDB	28649521
Human Saliva	Detected and Quantified	9.2	4.1			uM	Adult (>18 years old)	Male	Normal	HMDB	21164041
Human Saliva	Detected and Quantified	9.8	5.2			uM	Adult (>18 years old)	Male	Normal	HMDB	21164041
Human Blood	Detected and Quantified			92	325	uM	Infant (0-1 year old)	Not Specified	Normal	HMDB	20549362
Human Urine	Detected and Quantified	28.0899	25.2794			umol/mmol creatinine	Children (1 - 13 years old)	Not Specified	Eosinophilic esophagitis	HMDB	Analysis of 30 normal pediatric urine samples via NMR spectroscopy (unpublished work)
Human Urine	Detected and Quantified	34.402	30.429			umol/mmol creatinine	Children (1 - 13 years old)	Not Specified	Eosinophilic esophagitis	HMDB	Analysis of 30 normal pediatric urine samples via NMR spectroscopy (unpublished work)
Human Blood	Detected and Quantified	70		32	179	uM	Adult (>18 years old)	Not Specified	Lysinuric protein intolerance	HMDB	Lysinuric Protein Intolerance and Other Cationic Aminoacidurias. The metabolic and molecular bases of inherited disease, 7/e; Editors: C.R.Scriver, A.L.Beaudet, W.S.Sly, D.Valle; McGraw-Hill Inc. (1995) DOI: 10.1036/ommbid.225
Human Urine	Detected and Quantified	18.0		7.0	29.0	umol/mmol creatinine	Adult (>18 years old)	Both	Carbamoyl Phosphate Synthetase Deficiency	HMDB	MetaGene: Metabolic & Genetic Information Center (MIC: http://www.metagene.de)
Human Urine	Detected and Quantified	2750.0		500.0	5000.0	umol/mmol creatinine	Children (1-13 years old)	Both	Carbamoyl phosphate synthetase deficiency	HMDB	MetaGene: Metabolic & Genetic Information Center (MIC: http://www.metagene.de)
Human Urine	Detected and Quantified	23.654	19.414			umol/mmol creatinine	Children (1 - 13 years old)	Not Specified	Normal	HMDB	Analysis of 30 normal pediatric urine samples via NMR spectroscopy (unpublished work)
Human Urine	Detected and Quantified	34.8063	26.0145			umol/mmol creatinine	Children (1 - 13 years old)	Not Specified	Normal	HMDB	Analysis of 30 normal pediatric urine samples via NMR spectroscopy (unpublished work)
Human Urine	Detected and Quantified			0	66.37	umol/mmol creatinine	Adolescent (13 - 21 years old)	Both	Normal	HMDB	BC Children's Hospital Biochemical Genetics Lab
Human Urine	Detected and Quantified			0	66.37	umol/mmol creatinine	Adult (>21 years old)	Both	Normal	HMDB	BC Children's Hospital Biochemical Genetics Lab
Human Urine	Detected and Quantified			1.92	50.31	umol/mmol creatinine	Children (2 - 4 years old)	Both	Normal	HMDB	BC Children's Hospital Biochemical Genetics Lab
Human Urine	Detected and Quantified			1.92	79.82	umol/mmol creatinine	Children (4 - 13 years old)	Both	Normal	HMDB	BC Children's Hospital Biochemical Genetics Lab
Human Urine	Detected and Quantified			10.06	81.18	umol/mmol creatinine	Children (1 - 2 years old)	Both	Normal	HMDB	BC Children's Hospital Biochemical Genetics Lab
Human Blood	Detected and Quantified			108	270	uM	Children (6 - 18 years old)	Both	Normal	HMDB	BC Children's Hospital Biochemical Genetics Lab
Human Cerebrospinal fluid (csf)	Detected and Quantified			12	43	uM	Adolescent (>11 years old)	Both	Normal	HMDB	BC Children's Hospital Biochemical Genetics Lab
Human Urine	Detected and Quantified			18.09	217.98	umol/mmol creatinine	Newborn (0-30 days old)	Both	Normal	HMDB	BC Children's Hospital Biochemical Genetics Lab
Human Blood	Detected and Quantified			37	228	uM	Infant (1 - 3 months old)	Both	Normal	HMDB	BC Children's Hospital Biochemical Genetics Lab
Human Urine	Detected and Quantified			5.99	94.63	umol/mmol creatinine	Infant (6 months - <1 year old)	Both	Normal	HMDB	BC Children's Hospital Biochemical Genetics Lab
Human Cerebrospinal fluid (csf)	Detected and Quantified			6	37	uM	Children (0 - 10 years old)	Both	Normal	HMDB	BC Children's Hospital Biochemical Genetics Lab
Human Blood	Detected and Quantified			71	272	uM	Newborn (0-30 days old)	Both	Normal	HMDB	BC Children's Hospital Biochemical Genetics Lab
Human Urine	Detected and Quantified			8.71	199.10	umol/mmol creatinine	Infant (1 - 6 months old)	Both	Normal	HMDB	BC Children's Hospital Biochemical Genetics Lab
Human Blood	Detected and Quantified			85	250	uM	Children (3 months - 6 years old)	Both	Normal	HMDB	BC Children's Hospital Biochemical Genetics Lab
Human Urine	Detected and Quantified			3.42	75.29	umol/mmol creatinine	Adult (>18 years old)	Both	Normal	HMDB	David F. Putnam Composition and Concentrative Properties of Human Urine. NASA Contractor Report. July 1971
Human Blood	Detected and Quantified	164.0	28.0			uM	Children (1-13 years old)	Female	Normal	HMDB	Geigy Scientific Tables, 8th Rev edition, pp. 130. Edited by C. Lentner, West Cadwell, N.J.: Medical education Div., Ciba-Geigy Corp. Basel, Switzerland c1981-1992.
Human Blood	Detected and Quantified	183.0	34.0			uM	Adult (>18 years old)	Female	Normal	HMDB	Geigy Scientific Tables, 8th Rev edition, pp. 130. Edited by C. Lentner, West Cadwell, N.J.: Medical education Div., Ciba-Geigy Corp. Basel, Switzerland c1981-1992.
Human Blood	Detected and Quantified	190.0	60.0			uM	Newborn (0-30 days old)	Not Specified	Normal	HMDB	Geigy Scientific Tables, 8th Rev edition, pp. 130. Edited by C. Lentner, West Cadwell, N.J.: Medical education Div., Ciba-Geigy Corp. Basel, Switzerland c1981-1992.
Human Blood	Detected and Quantified	198.0	31.0			uM	Adult (>18 years old)	Male	Normal	HMDB	Geigy Scientific Tables, 8th Rev edition, pp. 130. Edited by C. Lentner, West Cadwell, N.J.: Medical education Div., Ciba-Geigy Corp. Basel, Switzerland c1981-1992.
Human Cerebrospinal fluid (csf)	Detected and Quantified	21.7	3.7			uM	Adult (>18 years old)	Both	Normal	HMDB	Geigy Scientific Tables, 8th Rev edition, pp. 130. Edited by C. Lentner, West Cadwell, N.J.: Medical education Div., Ciba-Geigy Corp. Basel, Switzerland c1981-1992.
Human Urine	Detected and Quantified	29.0	21.7			umol/mmol creatinine	Adult (>18 years old)	Female	Normal	HMDB	Geigy Scientific Tables, 8th Rev edition, pp. 130. Edited by C. Lentner, West Cadwell, N.J.: Medical education Div., Ciba-Geigy Corp. Basel, Switzerland c1981-1992.
Human Urine	Detected and Quantified	29.867	22.0667			umol/mmol creatinine	Adult (>18 years old)	Female	Normal	HMDB	Geigy Scientific Tables, 8th Rev edition, pp. 130. Edited by C. Lentner, West Cadwell, N.J.: Medical education Div., Ciba-Geigy Corp. Basel, Switzerland c1981-1992.
Human Urine	Detected and Quantified	32.0	27.0			umol/mmol creatinine	Adult (>18 years old)	Male	Normal	HMDB	Geigy Scientific Tables, 8th Rev edition, pp. 130. Edited by C. Lentner, West Cadwell, N.J.: Medical education Div., Ciba-Geigy Corp. Basel, Switzerland c1981-1992.
Human Urine	Detected and Quantified	32.800	27.667			umol/mmol creatinine	Adult (>18 years old)	Male	Normal	HMDB	Geigy Scientific Tables, 8th Rev edition, pp. 130. Edited by C. Lentner, West Cadwell, N.J.: Medical education Div., Ciba-Geigy Corp. Basel, Switzerland c1981-1992.
Human Urine	Detected and Quantified	68.22		12	124.44	umol/mmol creatinine	Newborn (0-30 days old)	Both	Normal	HMDB	Geigy Scientific Tables, 8th Rev edition, pp. 130. Edited by C. Lentner, West Cadwell, N.J.: Medical education Div., Ciba-Geigy Corp. Basel, Switzerland c1981-1992.
Human Urine	Detected and Quantified	7.467	6.360			umol/mmol creatinine	Children (1 - 13 years old)	Female	Normal	HMDB	Geigy Scientific Tables, 8th Rev edition, pp. 130. Edited by C. Lentner, West Cadwell, N.J.: Medical education Div., Ciba-Geigy Corp. Basel, Switzerland c1981-1992.
Human Urine	Detected and Quantified	9.0667	5.707			umol/mmol creatinine	Children (1 - 13 years old)	Male	Normal	HMDB	Geigy Scientific Tables, 8th Rev edition, pp. 130. Edited by C. Lentner, West Cadwell, N.J.: Medical education Div., Ciba-Geigy Corp. Basel, Switzerland c1981-1992.
Human Blood	Detected and Quantified			71	151	uM	Adult (>18 years old)	Not Specified	Normal	HMDB	Lysinuric Protein Intolerance and Other Cationic Aminoacidurias. The metabolic and molecular bases of inherited disease, 7/e; Editors: C.R.Scriver, A.L.Beaudet, W.S.Sly, D.Valle; McGraw-Hill Inc. (1995) DOI: 10.1036/ommbid.225
Human Saliva	Detected and Quantified	19.2	12.8			uM	Adult (>18 years old)	Female	Normal	HMDB	Sugimoto et al. (2013) Physiological and environmental parameters associated with mass spectrometry-based salivary metabolomic profiles.
Human Saliva	Detected and Quantified	45.1	45.0			uM	Adult (>18 years old)	Male	Normal	HMDB	Sugimoto et al. (2013) Physiological and environmental parameters associated with mass spectrometry-based salivary metabolomic profiles.
Human Saliva	Detected and Quantified	37.76	18.10			uM	Adult (>18 years old)	Both	Normal	HMDB	https://doi.org/10.1007/s11306-015-0840-5
Human Blood	Detected and Quantified			110.0	240.0	uM	Adult (>18 years old)	Both	Normal	HMDB	Molecular You (https://molecularyou.com)
Human Urine	Detected and Quantified			1.13	27.15	umol/mmol creatinine	Adolescent (13-18 years old)	Not Specified	Normal	HMDB	Mayo Clinic (https://neurology.testcatalog.org/show/AAPD)
Human Urine	Detected and Quantified			1.58	34.73	umol/mmol creatinine	Children (1-13 years old)	Not Specified	Normal	HMDB	Mayo Clinic (https://neurology.testcatalog.org/show/AAPD)
Human Urine	Detected and Quantified			1.70	30.65	umol/mmol creatinine	Adult (>18 years old)	Not Specified	Normal	HMDB	Mayo Clinic (https://neurology.testcatalog.org/show/AAPD)
Human Urine	Detected and Quantified			1.92	31.22	umol/mmol creatinine	Children (1-13 years old)	Not Specified	Normal	HMDB	Mayo Clinic (https://neurology.testcatalog.org/show/AAPD)
Human Urine	Detected and Quantified			2.15	224.84	umol/mmol creatinine	Infant (0-1 year old)	Not Specified	Normal	HMDB	Mayo Clinic (https://neurology.testcatalog.org/show/AAPD)
Human Urine	Detected and Quantified			2.83	84.047	umol/mmol creatinine	Children (1-13 years old)	Not Specified	Normal	HMDB	Mayo Clinic (https://neurology.testcatalog.org/show/AAPD)
Human All tissues	Detected but not Quantified						Not Specified	Not Specified	Normal	HMDB	34986597
Human Placenta	Detected but not Quantified						Not Specified	Not Specified	Normal	HMDB	34986597
Human Prostate	Detected but not Quantified						Not Specified	Not Specified	Normal	HMDB	34986597
Human Saliva	Detected but not Quantified						Adult (>18 years old)	Both	Normal	HMDB	20300169
Human Saliva	Detected but not Quantified						Adult (>18 years old)	Male	Normal	HMDB	22308371
Human Saliva	Detected but not Quantified						Adult (>18 years old)	Male	Normal	HMDB	22308371
Human Saliva	Detected but not Quantified						Adult (>18 years old)	Male	Normal	HMDB	22308371
Human Saliva	Detected but not Quantified						Adult (>18 years old)	Male	Normal	HMDB	22308371
Human Saliva	Detected but not Quantified						Adult (>18 years old)	Male	Normal	HMDB	22308371
Human Saliva	Detected but not Quantified						Adult (>18 years old)	Male	Normal	HMDB	22308371
Human Saliva	Detected but not Quantified						Adult (>18 years old)	Male	Normal	HMDB	22308371
Human Saliva	Detected but not Quantified						Adult (>18 years old)	Male	Normal	HMDB	22308371
Human Saliva	Detected but not Quantified						Adult (>18 years old)	Male	Normal	HMDB	22308371
Human Saliva	Detected but not Quantified						Adult (>18 years old)	Male	Normal	HMDB	22308371
Human Feces	Detected but not Quantified						Adult (>18 years old)	Both	Normal	HMDB	17269711
Human Feces	Detected but not Quantified						Adult (>18 years old)	Both	Normal	HMDB	18052033
Human Feces	Detected but not Quantified						Adult (>18 years old)	Both	Normal	HMDB	18085514
Human Feces	Detected but not Quantified						Not Specified	Not Specified	Normal	HMDB	19573517
Human Feces	Detected but not Quantified						Not Specified	Not Specified	Normal	HMDB	20669995
Human Feces	Detected but not Quantified						Adult (>18 years old)	Both	Normal	HMDB	21761941
Human Feces	Detected but not Quantified						Infant (0-1 year old)	Both	Normal	HMDB	22411374
Human Feces	Detected but not Quantified						Adult (>18 years old)	Both	Normal	HMDB	23940645
Human Blood	Detected but not Quantified						Adult (>18 years old)	Both	Normal	HMDB	20143319
Human Feces	Detected but not Quantified						Adult (>18 years old)	Both	Normal	HMDB	25670064
Human Feces	Detected but not Quantified						Adult (>18 years old)	Female	Normal	HMDB	26709303
Human Feces	Detected but not Quantified						Not Specified	Both	Normal	HMDB	25486321
Human Feces	Detected but not Quantified						Adult (>18 years old)	Both	Normal	HMDB	17269711
Human Feces	Detected but not Quantified						Children (1-13 years old)	Both	Normal	HMDB	24130822
Human Feces	Detected but not Quantified						Adult (>18 years old)	Both	Normal	HMDB	27065191
Human Feces	Detected but not Quantified						Children (6 - 18 years old)	Not Specified	Normal	HMDB	27609529
Human Sweat	Detected but not Quantified						Adult	Both	Normal	HMDB	26755145
Human Feces	Detected but not Quantified						Adult (>18 years old)	Both	Normal	HMDB	27543620
Human Feces	Detected but not Quantified						Adult (>18 years old)	Both	Normal	HMDB	25037050
Human Feces	Detected but not Quantified						Adult (>18 years old)	Not Specified	Normal	HMDB	25985090
Human Feces	Detected but not Quantified						Adult (>18 years old)	Both	Normal	HMDB	29808030
Human Urine	Detected but not Quantified						Adult (>18 years old)	Both	Normal	HMDB	28157703
Human Urine	Detected but not Quantified						Adult (>18 years old)	Both	Normal	HMDB	32966057
Human Blood	Detected but not Quantified						Adult (>18 years old)	Both	Normal	HMDB	32966057

External Links

References

General References

Kranz BR: Detection of rare malignant cells and their apoptotic fragments in cerebrospinal fluid. Lancet. 2000 Oct 7;356(9237):1242-4. doi: 10.1016/S0140-6736(00)02794-X. [PubMed:11072949 ]
Peng CT, Wu KH, Lan SJ, Tsai JJ, Tsai FJ, Tsai CH: Amino acid concentrations in cerebrospinal fluid in children with acute lymphoblastic leukemia undergoing chemotherapy. Eur J Cancer. 2005 May;41(8):1158-63. doi: 10.1016/j.ejca.2005.02.013. Epub 2005 Apr 14. [PubMed:15911239 ]
Cynober LA: Plasma amino acid levels with a note on membrane transport: characteristics, regulation, and metabolic significance. Nutrition. 2002 Sep;18(9):761-6. doi: 10.1016/s0899-9007(02)00780-3. [PubMed:12297216 ]
Rainesalo S, Keranen T, Palmio J, Peltola J, Oja SS, Saransaari P: Plasma and cerebrospinal fluid amino acids in epileptic patients. Neurochem Res. 2004 Jan;29(1):319-24. doi: 10.1023/b:nere.0000010461.34920.0c. [PubMed:14992292 ]
Silwood CJ, Lynch E, Claxson AW, Grootveld MC: 1H and (13)C NMR spectroscopic analysis of human saliva. J Dent Res. 2002 Jun;81(6):422-7. doi: 10.1177/154405910208100613. [PubMed:12097436 ]
Hajishengallis G, Koga T, Russell MW: Affinity and specificity of the interactions between Streptococcus mutans antigen I/II and salivary components. J Dent Res. 1994 Sep;73(9):1493-502. doi: 10.1177/00220345940730090301. [PubMed:7523469 ]
Pahler A, Parker J, Dekant W: Dose-dependent protein adduct formation in kidney, liver, and blood of rats and in human blood after perchloroethene inhalation. Toxicol Sci. 1999 Mar;48(1):5-13. doi: 10.1093/toxsci/48.1.5. [PubMed:10330678 ]
Nicholson JK, O'Flynn MP, Sadler PJ, Macleod AF, Juul SM, Sonksen PH: Proton-nuclear-magnetic-resonance studies of serum, plasma and urine from fasting normal and diabetic subjects. Biochem J. 1984 Jan 15;217(2):365-75. doi: 10.1042/bj2170365. [PubMed:6696735 ]
Engelborghs S, Marescau B, De Deyn PP: Amino acids and biogenic amines in cerebrospinal fluid of patients with Parkinson's disease. Neurochem Res. 2003 Aug;28(8):1145-50. doi: 10.1023/a:1024255208563. [PubMed:12834252 ]
Faraasen S, Voros J, Csucs G, Textor M, Merkle HP, Walter E: Ligand-specific targeting of microspheres to phagocytes by surface modification with poly(L-lysine)-grafted poly(ethylene glycol) conjugate. Pharm Res. 2003 Feb;20(2):237-46. doi: 10.1023/a:1022366921298. [PubMed:12636162 ]
Hagenfeldt L, Bjerkenstedt L, Edman G, Sedvall G, Wiesel FA: Amino acids in plasma and CSF and monoamine metabolites in CSF: interrelationship in healthy subjects. J Neurochem. 1984 Mar;42(3):833-7. doi: 10.1111/j.1471-4159.1984.tb02756.x. [PubMed:6198473 ]
Sreekumar A, Poisson LM, Rajendiran TM, Khan AP, Cao Q, Yu J, Laxman B, Mehra R, Lonigro RJ, Li Y, Nyati MK, Ahsan A, Kalyana-Sundaram S, Han B, Cao X, Byun J, Omenn GS, Ghosh D, Pennathur S, Alexander DC, Berger A, Shuster JR, Wei JT, Varambally S, Beecher C, Chinnaiyan AM: Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression. Nature. 2009 Feb 12;457(7231):910-4. doi: 10.1038/nature07762. [PubMed:19212411 ]
Brunk E, Sahoo S, Zielinski DC, Altunkaya A, Drager A, Mih N, Gatto F, Nilsson A, Preciat Gonzalez GA, Aurich MK, Prlic A, Sastry A, Danielsdottir AD, Heinken A, Noronha A, Rose PW, Burley SK, Fleming RMT, Nielsen J, Thiele I, Palsson BO: Recon3D enables a three-dimensional view of gene variation in human metabolism. Nat Biotechnol. 2018 Mar;36(3):272-281. doi: 10.1038/nbt.4072. Epub 2018 Feb 19. [PubMed:29457794 ]
Elshenawy S, Pinney SE, Stuart T, Doulias PT, Zura G, Parry S, Elovitz MA, Bennett MJ, Bansal A, Strauss JF 3rd, Ischiropoulos H, Simmons RA: The Metabolomic Signature of the Placenta in Spontaneous Preterm Birth. Int J Mol Sci. 2020 Feb 4;21(3). pii: ijms21031043. doi: 10.3390/ijms21031043. [PubMed:32033212 ]

Showing metabocard for L-Lysine (MMDBc0000059)

MOL for #<Metabolite:0x00007fd5c45d9f98>

3D MOL for #<Metabolite:0x00007fd5c45d9f98>

3D SDF for #<Metabolite:0x00007fd5c45d9f98>

3D-SDF for #<Metabolite:0x00007fd5c45d9f98>

PDB for #<Metabolite:0x00007fd5c45d9f98>

3D PDB for #<Metabolite:0x00007fd5c45d9f98>

SMILES for #<Metabolite:0x00007fd5c45d9f98>

INCHI for #<Metabolite:0x00007fd5c45d9f98>

Structure for #<Metabolite:0x00007fd5c45d9f98>

3D Structure for #<Metabolite:0x00007fd5c45d9f98>