MiMeDB: Health Effects

Host:

Health Outcome:

Bioactivity:

Metabolites
Microbes

Metabolite ID	Name	Formula MW	Host & biospecimen (status - Q; D; E; P)	# Related Microbes	Health outcome	Bioactivity and targets
MMDBc0000001	Indoxyl sulfate	C₈H₇NO₄S 213.21	Human Urine Human Blood Human Feces Human Cerebrospinal Fluid (CSF) Human Bone Marrow Human Brain Human Endothelial tissue Human Heart Human Kidney Human Liver Human Skeletal Muscle	0	Uremia Eosinophilic esophagitis anxiolytic depressant cognitive impairment kidney damage heart damage liver damage nerve/brain damage atherogenic	Uremic toxin
MMDBc0000002	p-Cresol sulfate	C₇H₈O₄S 188.201	Human Blood Human Urine Human Saliva Human Feces Human Cerebrospinal Fluid (CSF) Human Placenta	8	Uremia Eosinophilic esophagitis anxiolytic depressant cognitive impairment kidney damage heart damage liver damage nerve/brain damage atherogenic Chronic Kidney Disease Aging Parkinson's disease	Uremic toxin Pro-inflammatory ROS production
MMDBc0000003	p-Cresol	C₇H₈O 108.1378	Human Urine Human Blood Human Feces Human Saliva Human Adipose Tissue Human Fibroblasts	15	Celiac disease Crohn's disease Irritable bowel syndrome Ulcerative colitis Uremia Eosinophilic esophagitis kidney damage heart damage liver damage nerve/brain damage atherogenic mosquito attractant Chronic Kidney Disease Clostridium difficile infection	Uremic toxin Neurotoxin
MMDBc0000004	Indole	C₈H₇N 117.1479	Human Feces Human Urine Human Saliva Human Blood Human Epidermis Human Fibroblasts Human Intestine Human Neuron	784	Celiac disease Crohn's disease Irritable bowel syndrome Ulcerative colitis
MMDBc0000005	2-Ketobutyric acid	C₄H₆O₃ 102.0886	Human Feces Human Urine Human Blood Human Cerebrospinal Fluid (CSF) Human Saliva	1151	Eosinophilic esophagitis
MMDBc0000006	Biotin	C₁₀H₁₆N₂O₃S 244.311	Human Feces Human Cerebrospinal Fluid (CSF) Human Blood Human Urine Human Saliva Human All Tissues Human Prostate	1425	Acute Lymphoblastic Leukemia Dementia Epilepsy Motor neuron disease Multiple sclerosis Eosinophilic esophagitis
MMDBc0000007	Carnosine	C₉H₁₄N₄O₃ 226.2325	Human Feces Human Urine Human Blood Human Saliva Human Brain Human Fibroblasts Human Intestine Human Kidney Human Liver Human Neuron Human Placenta Human Skeletal Muscle	820	Alzheimer's disease Carnosinuria Eosinophilic esophagitis
MMDBc0000008	Adenine	C₅H₅N₅ 135.1267	Human Feces Human Saliva Human Cerebrospinal Fluid (CSF) Human Blood Human Urine Human All Tissues Human Placenta Human Prostate	1788	Alzheimer's disease Frontotemporal dementia Meningitis Tuberculous meningitis Eosinophilic esophagitis
MMDBc0000009	Taurocholic acid	C₂₆H₄₅NO₇S 515.703	Human Feces Human Urine Human Blood Human Bile Human Fibroblasts Human Intestine Human Liver Human Neuron Human Placenta	210	Biliary atresia
MMDBc0000010	Butyric acid	C₄H₈O₂ 88.1051	Human Feces Human Urine Human Saliva Human Breath Human Breast Milk Human Blood Human Cerebrospinal Fluid (CSF) Human Fibroblasts Human Intestine Human Kidney Human Neuron Human Prostate Human Skeletal Muscle	778	AIDS Celiac disease Crohn's disease Irritable bowel syndrome Ulcerative colitis Eosinophilic esophagitis
MMDBc0000011	Acetic acid	C₂H₄O₂ 60.052	Human Cerebrospinal Fluid (CSF) Human Feces Human Saliva Human Breath Human Urine Human Blood Human Breast Milk Human Kidney Human Liver	2537	Argininosuccinic aciduria Celiac disease Lung Cancer Maple syrup urine disease Multiple sclerosis Phenylketonuria Propionic acidemia Tyrosinemia I Eosinophilic esophagitis
MMDBc0000012	Betaine	C₅H₁₂NO₂ 118.1543	Human Feces Human Saliva Human Urine Human Blood Human Breast Milk Human Adipose Tissue Human Adrenal Cortex Human Adrenal Gland Human Bladder Human Epidermis Human Fibroblasts Human Intestine Human Kidney Human Liver Human Ovary Human Pancreas Human Placenta Human Platelet Human Prostate Human Skeletal Muscle Human Spleen Human Testis	1062	Alzheimer's disease Argininosuccinic aciduria Dimethylglycine Dehydrogenase Deficiency Frontotemporal dementia Hypermethioninemia Lung Cancer Maple syrup urine disease Phenylketonuria Propionic acidemia Schizophrenia Eosinophilic esophagitis
MMDBc0000013	Ascorbic acid	C₆H₈O₆ 176.1241	Human Feces Human Blood Human Cerebrospinal Fluid (CSF) Human Urine Human Saliva Human Amniotic Fluid Human Breast Milk Human Cellular Cytoplasm Human Adipose Tissue Human Adrenal Cortex Human Adrenal Medulla Human Bladder Human Brain Human Epidermis Human Erythrocyte Human Eye Lens Human Fibroblasts Human Heart Human Intestine Human Leukocyte Human Liver Human Lung Human Neuron Human Ovary Human Placenta Human Platelet Human Prostate Human Skeletal Muscle Human Spleen Human Testis	37	Canavan disease Hyperoxalemia Meningitis Traumatic brain injury Eosinophilic esophagitis
MMDBc0000014	Melibiose	C₁₂H₂₂O₁₁ 342.2965	Human Urine Human Spleen Human Blood	87	Not Available	Not Available
MMDBc0000015	Adenosine	C₁₀H₁₃N₅O₄ 267.2413	Human Feces Human Urine Human Saliva Human Blood Human Cerebrospinal Fluid (CSF) Human Cellular Cytoplasm Human Breast Milk Human All Tissues Human Placenta	1619	Adenylosuccinate lyase deficiency Alzheimer's disease Frontotemporal dementia Septic shock Eosinophilic esophagitis
MMDBc0000016	Ammonia	H₃N 17.0305	Human Feces Human Blood Human Urine Human Cellular Cytoplasm Human Cerebrospinal Fluid (CSF) Human All Tissues	1850	3-Hydroxy-3-methylglutaryl-CoA lyase deficiency Argininosuccinic aciduria Carnitine palmitoyltransferase I deficiency Citrullinemia type I Fumarase deficiency Hyperdibasic aminoaciduria I Mitochondrial trifunctional protein deficiency N-acetylglutamate synthetase deficiency Pyruvate carboxylase deficiency Short bowel syndrome 3-Methyl-crotonyl-glycinuria
MMDBc0000017	Cellobiose	C₁₂H₂₂O₁₁ 342.2965	Human Urine Human Intestine Human Spleen Human Blood	823	Not Available	Not Available
MMDBc0000018	beta-Alanine	C₃H₇NO₂ 89.0932	Human Feces Human Saliva Human Cerebrospinal Fluid (CSF) Human Urine Human Blood Human Kidney Human Pancreas Human Placenta Human Prostate Human Skeletal Muscle	1256	Alzheimer's disease Dihydropyrimidine dehydrogenase deficiency Frontotemporal dementia Methylmalonate semialdehyde dehydrogenase deficiency Eosinophilic esophagitis Gaba-transaminase deficiency Hyper beta-alaninemia
MMDBc0000019	L-Carnitine	C₇H₁₆NO₃ 162.2068	Human Feces Human Blood Human Urine Human Cerebrospinal Fluid (CSF) Human Breast Milk Human Saliva Human Adipose Tissue Human Bladder Human Brain Human Erythrocyte Human Fibroblasts Human Heart Human Intestine Human Kidney Human Liver Human Lung Human Neuron Human Placenta Human Platelet Human Prostate Human Semen Human Skeletal Muscle Human Testis	183	3-Hydroxy-3-methylglutaryl-CoA lyase deficiency Carnitine palmitoyltransferase I deficiency Diabetes mellitus type 2 L-2-Hydroxyglutaric aciduria Lung Cancer Mitochondrial trifunctional protein deficiency Obesity Oculocerebrorenal syndrome Propionic acidemia Eosinophilic esophagitis
MMDBc0000020	Cholesterol	C₂₇H₄₆O 386.6535	Human Feces Human Blood Human Bile Human Cerebrospinal Fluid (CSF) Human Saliva Human All Tissues Human Placenta Human Prostate Human Urine	27	Abetalipoproteinemia Acute myelogenous leukemia Cerebrotendinous xanthomatosis Cholelithiasis Cholesteryl ester storage disease Cystinosis Gallbladder disease Hypercholesterolemia Hyperlipoproteinemia Multiple sclerosis Oculocerebrorenal syndrome Primary hypomagnesemia Smith-Lemli-Opitz syndrome Stomach cancer
MMDBc0000021	cis-Aconitic acid	C₆H₆O₆ 174.1082	Human Feces Human Saliva Human Urine Human Cerebrospinal Fluid (CSF) Human Sweat Human Breast Milk Human Prostate Human Blood	11	Alzheimer's disease Frontotemporal dementia Lung Cancer Eosinophilic esophagitis
MMDBc0000022	Dimethylamine	C₂H₇N 45.0837	Human Blood Human Urine Human Saliva Human Cerebrospinal Fluid (CSF) Human Feces Human Sweat Human Fibroblasts Human Neuron	119	Diabetes mellitus type 2 Kidney disease Rhabdomyolysis Uremia Eosinophilic esophagitis Diabetes mellitus type 1
MMDBc0000023	Cytidine	C₉H₁₃N₃O₅ 243.2166	Human Feces Human Saliva Human Blood Human Urine Human Cerebrospinal Fluid (CSF) Human Breast Milk Human All Tissues Human Placenta Human Prostate	1679	Alzheimer's disease Canavan disease Frontotemporal dementia Uremia
MMDBc0000024	Citric acid	C₆H₈O₇ 192.1235	Human Feces Human Cerebrospinal Fluid (CSF) Human Blood Human Saliva Human Urine Human Breast Milk Human All Tissues Human Placenta Human Prostate Human Sweat	1285	2-Ketoglutarate dehydrogenase complex deficiency Alzheimer's disease Argininosuccinic aciduria Canavan disease Frontotemporal dementia Hyperoxalemia Lung Cancer Maple syrup urine disease Paraquat poisoning Phenylketonuria Primary hypomagnesemia Propionic acidemia Rhabdomyolysis Tyrosinemia I Eosinophilic esophagitis Diabetes mellitus type 1
MMDBc0000025	Choline	C₅H₁₄NO 104.1708	Human Feces Human Cerebrospinal Fluid (CSF) Human Saliva Human Blood Human Urine Human Sweat Human Breast Milk Human Basal Ganglia Human Bladder Human Brain Human Epidermis Human Fibroblasts Human Intestine Human Kidney Human Liver Human Neuron Human Placenta Human Platelet Human Prostate Human Skeletal Muscle Human Spleen Human Testis	1144	Alzheimer's disease Frontotemporal dementia Lung Cancer Multi-infarct dementia Spina Bifida Eosinophilic esophagitis

Microbe ID	Organism	Kindgom	Phylum	Energy production	Host and body site	# Related metabolites	Pathogenicity and disease	Related health outcome
MMDBm0000001	Bacteroides fragills NCTC 9343	Not Available	microspora	Not Available	Human Feces	0	Not Available	Not Available
MMDBm0000002	Micromonospora aurantiaca ATCC 27029	Not Available	Actinobacteria	Not Available	Human Feces	812	Not Available	Not Available
MMDBm0000003	Acidaminococcus fermentans DSM 20731	Not Available	Firmicutes	Not Available	Pig	660	Not Available	Not Available
MMDBm0000004	Acidaminococcus intestini RyC-MR95	Not Available	Firmicutes	Not Available	Human Feces	580	Not Available	Not Available
MMDBm0000005	Acidovorax sp. KKS102	Not Available	Proteobacteria	Not Available	Human Feces	0	Not Available	Not Available
MMDBm0000006	Acinetobacter baumannii	Not Available	Proteobacteria	Not Available	Human	39	Not Available	Not Available
MMDBm0000007	Acinetobacter pittii ANC 4052	Not Available	Proteobacteria	Not Available	Human Feces	837	Not Available	Not Available
MMDBm0000008	Acinetobacter radioresistens NIPH 2130	Not Available	Proteobacteria	Not Available	Human Feces	791	Not Available	Not Available
MMDBm0000009	Adlercreutzia equolifaciens DSM 19450	Not Available	Actinobacteria	Not Available	Human Feces	553	Not Available	Not Available
MMDBm0000010	Aeromonas jandaei Riv2	Not Available	Proteobacteria	Not Available	Human Feces	847	Not Available	Not Available
MMDBm0000011	Aggregatibacter aphrophilus NJ8700	Not Available	Proteobacteria	Not Available	Human	706	Not Available	Not Available
MMDBm0000012	Agrobacterium tumefaciens F2	Not Available	Proteobacteria	Not Available	Human Feces	858	Not Available	Not Available
MMDBm0000013	Akkermansia	Not Available	Verrucomicrobia	Not Available	Human Feces	0	Not Available	Not Available
MMDBm0000014	Akkermansia muciniphila	Not Available	Verrucomicrobia	Not Available	Human Feces	116	Not Available	Not Available
MMDBm0000015	Akkermansia muciniphila ATCC BAA-835	Not Available	Verrucomicrobia	Not Available	Human	659	Not Available	Not Available
MMDBm0000016	Alcaligenes faecalis subsp. faecalis NBRC 13111	Not Available	Proteobacteria	Not Available	Human Feces	807	Not Available	Not Available
MMDBm0000017	Alistipes	Not Available	Bacteroidetes	Not Available	Human Feces	0	Not Available	Not Available
MMDBm0000018	Alistipes finegoldii DSM 17242	Not Available	Bacteroidetes	Not Available	Human Feces	621	Not Available	Not Available
MMDBm0000019	Alistipes shahii WAL 8301	Not Available	Bacteroidetes	Not Available	Human Feces	598	Not Available	Not Available
MMDBm0000020	Anaerococcus prevotii DSM 20548	Not Available	Firmicutes	Not Available	Human	631	Not Available	Not Available
MMDBm0000021	Anaerostipes caccae	Not Available	Firmicutes	Not Available	Human Feces	588	Not Available	Not Available
MMDBm0000022	Anaerostipes hadrus	Not Available	Firmicutes	Not Available	Human Feces	42	Not Available	Not Available
MMDBm0000023	Arcobacter butzleri RM4018	Not Available	Proteobacteria	Not Available	Human	665	Not Available	Not Available
MMDBm0000024	Bacillus altitudinis 41KF2b	Not Available	Firmicutes	Not Available	Human Feces	836	Not Available	Not Available
MMDBm0000025	Bacillus amyloliquefaciens subsp. amyloliquefaciens DC-12	Not Available	Firmicutes	Not Available	Human Feces	844	Not Available	Not Available

Health Effects

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