MiMeDB: Showing metabocard for gamma-Glutamylleucine (MMDBc0000446)

Record Information

Version

1.0

Status

Detected and Quantified

Creation Date

2020-12-10 18:37:56 UTC

Update Date

2024-04-30 19:32:26 UTC

Metabolite ID

MMDBc0000446

Metabolite Identification

Common Name

gamma-Glutamylleucine

Description

gamma-Glutamylleucine is a dipeptide composed of gamma-glutamate and leucine, and is a proteolytic breakdown product of larger proteins. It belongs to the family of N-acyl-alpha amino acids and derivatives. These are compounds containing an alpha amino acid which bears an acyl group at its terminal nitrogen atom. gamma-Glutamylleucine is an incomplete breakdown product of protein digestion or protein catabolism. Some dipeptides are known to have physiological or cell-signaling effects although most are simply short-lived intermediates on their way to specific amino acid degradation pathways following further proteolysis. gamma-Glutamylleucine is a biomarker for the consumption of whey protein. It is found in urine (PMID: 3782411 ).

Structure

MOL 3D MOL SDF 3D SDF PDB 3D PDB SMILES InChI

HMDB0011171
     RDKit          3D
gamma-Glutamylleucine
 38 37  0  0  0  0  0  0  0  0999 V2000
   -4.4365   -0.4895    0.9861 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.1085   -0.3327    0.1969 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0008   -0.9279    0.9909 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9422    1.1077   -0.1414 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7254    1.4224   -0.9259 C   0  0  2  0  0  0  0  0  0  0  0  0
   -0.4883    1.1236   -0.2965 N   0  0  0  0  0  0  0  0  0  0  0  0
    0.4447    0.1955   -0.8107 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.2591   -0.4492   -1.8755 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.7094   -0.0466   -0.0779 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5667   -1.0601   -0.7773 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.8540   -1.3303   -0.0645 C   0  0  2  0  0  0  0  0  0  0  0  0
    4.6760   -0.1495    0.0758 N   0  0  0  0  0  0  0  0  0  0  0  0
    4.5825   -2.3809   -0.8382 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9738   -3.4621   -1.0308 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.8668   -2.1265   -1.2998 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7896    2.8136   -1.4474 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8220    3.5690   -1.3065 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9258    3.2370   -2.0783 O   0  0  0  0  0  0  0  0  0  0  0  0
   -4.6677   -1.5549    0.9684 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3239   -0.0615    2.0033 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.1665    0.1391    0.4383 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2749   -0.9334   -0.7194 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3827   -0.1721    1.4687 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3754   -1.6145    0.3705 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4646   -1.5729    1.8080 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8774    1.4682   -0.6776 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9225    1.7371    0.8103 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7903    0.7873   -1.8781 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2542    1.6324    0.5829 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.2268    0.9195    0.0601 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.5137   -0.4479    0.9514 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.7629   -0.6754   -1.8000 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.0141   -2.0111   -0.8547 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.6758   -1.7487    0.9378 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.2525    0.6806   -0.3949 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.9145    0.0322    1.0758 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.0192   -1.2324   -1.7512 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5735    3.9150   -1.6798 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  1  0
  2  4  1  0
  4  5  1  0
  5  6  1  0
  6  7  1  0
  7  8  2  0
  7  9  1  0
  9 10  1  0
 10 11  1  0
 11 12  1  0
 11 13  1  0
 13 14  2  0
 13 15  1  0
  5 16  1  0
 16 17  2  0
 16 18  1  0
  1 19  1  0
  1 20  1  0
  1 21  1  0
  2 22  1  0
  3 23  1  0
  3 24  1  0
  3 25  1  0
  4 26  1  0
  4 27  1  0
  5 28  1  6
  6 29  1  0
  9 30  1  0
  9 31  1  0
 10 32  1  0
 10 33  1  0
 11 34  1  1
 12 35  1  0
 12 36  1  0
 15 37  1  0
 18 38  1  0
M  END

  Mrv1652305052017392D          

 18 17  0  0  0  0            999 V2000
 2498.9283 2499.5885    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
 2498.9283 2500.4135    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
 2499.6427 2500.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
 2500.3572 2500.4135    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
 2501.0716 2500.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
 2501.7861 2500.4135    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
 2502.5005 2500.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
 2503.2150 2500.4135    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
 2502.5005 2501.6500    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
 2501.7861 2499.5885    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
 2499.6427 2501.6500    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
 2498.2138 2499.1749    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
 2497.4994 2499.5885    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
 2496.7849 2499.1749    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
 2497.4994 2500.4135    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
 2499.6427 2499.1749    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
 2500.3572 2499.5885    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
 2499.6427 2498.3499    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  6  0  0  0
  1 12  1  0  0  0  0
  1 16  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  1  0  0  0  0
  3 11  2  0  0  0  0
  4  5  1  0  0  0  0
  5  6  1  0  0  0  0
  6  7  1  0  0  0  0
  6 10  1  1  0  0  0
  7  8  1  0  0  0  0
  7  9  2  0  0  0  0
 12 13  1  0  0  0  0
 13 14  1  0  0  0  0
 13 15  1  0  0  0  0
 16 17  1  0  0  0  0
 16 18  2  0  0  0  0
M  END
> <DATABASE_ID>
MMDBc0000446

> <DATABASE_NAME>
MIME

> <SMILES>
CC(C)C[C@H](NC(=O)CC[C@H](N)C(O)=O)C(O)=O

> <INCHI_IDENTIFIER>
InChI=1S/C11H20N2O5/c1-6(2)5-8(11(17)18)13-9(14)4-3-7(12)10(15)16/h6-8H,3-5,12H2,1-2H3,(H,13,14)(H,15,16)(H,17,18)/t7-,8-/m0/s1

> <INCHI_KEY>
MYFMARDICOWMQP-YUMQZZPRSA-N

> <FORMULA>
C11H20N2O5

> <MOLECULAR_WEIGHT>
260.2869

> <EXACT_MASS>
260.13722176

> <JCHEM_ACCEPTOR_COUNT>
6

> <JCHEM_ATOM_COUNT>
38

> <JCHEM_AVERAGE_POLARIZABILITY>
26.293109806182578

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
4

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
(2S)-2-[(4S)-4-amino-4-carboxybutanamido]-4-methylpentanoic acid

> <ALOGPS_LOGP>
-2.60

> <JCHEM_LOGP>
-2.5341399150650585

> <ALOGPS_LOGS>
-1.76

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
0

> <JCHEM_PHYSIOLOGICAL_CHARGE>
-1

> <JCHEM_PKA>
4.033435154795595

> <JCHEM_PKA_STRONGEST_ACIDIC>
1.7836665127960734

> <JCHEM_PKA_STRONGEST_BASIC>
9.31207967883151

> <JCHEM_POLAR_SURFACE_AREA>
129.72

> <JCHEM_REFRACTIVITY>
62.25870000000001

> <JCHEM_ROTATABLE_BOND_COUNT>
8

> <JCHEM_RULE_OF_FIVE>
1

> <ALOGPS_SOLUBILITY>
4.48e+00 g/l

> <JCHEM_TRADITIONAL_IUPAC>
(2S)-2-[(4S)-4-amino-4-carboxybutanamido]-4-methylpentanoic acid

> <JCHEM_VEBER_RULE>
0

$$$$

HMDB0011171
     RDKit          3D
gamma-Glutamylleucine
 38 37  0  0  0  0  0  0  0  0999 V2000
   -4.4365   -0.4895    0.9861 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.1085   -0.3327    0.1969 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0008   -0.9279    0.9909 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9422    1.1077   -0.1414 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7254    1.4224   -0.9259 C   0  0  2  0  0  0  0  0  0  0  0  0
   -0.4883    1.1236   -0.2965 N   0  0  0  0  0  0  0  0  0  0  0  0
    0.4447    0.1955   -0.8107 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.2591   -0.4492   -1.8755 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.7094   -0.0466   -0.0779 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5667   -1.0601   -0.7773 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.8540   -1.3303   -0.0645 C   0  0  2  0  0  0  0  0  0  0  0  0
    4.6760   -0.1495    0.0758 N   0  0  0  0  0  0  0  0  0  0  0  0
    4.5825   -2.3809   -0.8382 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9738   -3.4621   -1.0308 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.8668   -2.1265   -1.2998 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7896    2.8136   -1.4474 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8220    3.5690   -1.3065 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9258    3.2370   -2.0783 O   0  0  0  0  0  0  0  0  0  0  0  0
   -4.6677   -1.5549    0.9684 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3239   -0.0615    2.0033 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.1665    0.1391    0.4383 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2749   -0.9334   -0.7194 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3827   -0.1721    1.4687 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3754   -1.6145    0.3705 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4646   -1.5729    1.8080 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8774    1.4682   -0.6776 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9225    1.7371    0.8103 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7903    0.7873   -1.8781 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2542    1.6324    0.5829 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.2268    0.9195    0.0601 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.5137   -0.4479    0.9514 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.7629   -0.6754   -1.8000 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.0141   -2.0111   -0.8547 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.6758   -1.7487    0.9378 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.2525    0.6806   -0.3949 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.9145    0.0322    1.0758 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.0192   -1.2324   -1.7512 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5735    3.9150   -1.6798 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  1  0
  2  4  1  0
  4  5  1  0
  5  6  1  0
  6  7  1  0
  7  8  2  0
  7  9  1  0
  9 10  1  0
 10 11  1  0
 11 12  1  0
 11 13  1  0
 13 14  2  0
 13 15  1  0
  5 16  1  0
 16 17  2  0
 16 18  1  0
  1 19  1  0
  1 20  1  0
  1 21  1  0
  2 22  1  0
  3 23  1  0
  3 24  1  0
  3 25  1  0
  4 26  1  0
  4 27  1  0
  5 28  1  6
  6 29  1  0
  9 30  1  0
  9 31  1  0
 10 32  1  0
 10 33  1  0
 11 34  1  1
 12 35  1  0
 12 36  1  0
 15 37  1  0
 18 38  1  0
M  END

HEADER    PROTEIN                                 05-MAY-20   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   05-MAY-20         0                                  
HETATM    1  C   UNK     0    4664.6664665.899   0.000  0.00  0.00           C+0
HETATM    2  N   UNK     0    4664.6664667.439   0.000  0.00  0.00           N+0
HETATM    3  C   UNK     0    4666.0004668.207   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0    4667.3334667.439   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0    4668.6674668.207   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0    4670.0014667.439   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0    4671.3344668.207   0.000  0.00  0.00           C+0
HETATM    8  O   UNK     0    4672.6684667.439   0.000  0.00  0.00           O+0
HETATM    9  O   UNK     0    4671.3344669.747   0.000  0.00  0.00           O+0
HETATM   10  N   UNK     0    4670.0014665.899   0.000  0.00  0.00           N+0
HETATM   11  O   UNK     0    4666.0004669.747   0.000  0.00  0.00           O+0
HETATM   12  C   UNK     0    4663.3324665.126   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0    4661.9994665.899   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0    4660.6654665.126   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0    4661.9994667.439   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0    4666.0004665.126   0.000  0.00  0.00           C+0
HETATM   17  O   UNK     0    4667.3334665.899   0.000  0.00  0.00           O+0
HETATM   18  O   UNK     0    4666.0004663.586   0.000  0.00  0.00           O+0
CONECT    1    2   12   16                                                  
CONECT    2    1    3                                                       
CONECT    3    2    4   11                                                  
CONECT    4    3    5                                                       
CONECT    5    4    6                                                       
CONECT    6    5    7   10                                                  
CONECT    7    6    8    9                                                  
CONECT    8    7                                                            
CONECT    9    7                                                            
CONECT   10    6                                                            
CONECT   11    3                                                            
CONECT   12    1   13                                                       
CONECT   13   12   14   15                                                  
CONECT   14   13                                                            
CONECT   15   13                                                            
CONECT   16    1   17   18                                                  
CONECT   17   16                                                            
CONECT   18   16                                                            
MASTER        0    0    0    0    0    0    0    0   18    0   34    0
END

COMPND    HMDB0011171
HETATM    1  C1  UNL     1      -4.437  -0.489   0.986  1.00  0.00           C  
HETATM    2  C2  UNL     1      -3.109  -0.333   0.197  1.00  0.00           C  
HETATM    3  C3  UNL     1      -2.001  -0.928   0.991  1.00  0.00           C  
HETATM    4  C4  UNL     1      -2.942   1.108  -0.141  1.00  0.00           C  
HETATM    5  C5  UNL     1      -1.725   1.422  -0.926  1.00  0.00           C  
HETATM    6  N1  UNL     1      -0.488   1.124  -0.297  1.00  0.00           N  
HETATM    7  C6  UNL     1       0.445   0.196  -0.811  1.00  0.00           C  
HETATM    8  O1  UNL     1       0.259  -0.449  -1.876  1.00  0.00           O  
HETATM    9  C7  UNL     1       1.709  -0.047  -0.078  1.00  0.00           C  
HETATM   10  C8  UNL     1       2.567  -1.060  -0.777  1.00  0.00           C  
HETATM   11  C9  UNL     1       3.854  -1.330  -0.064  1.00  0.00           C  
HETATM   12  N2  UNL     1       4.676  -0.149   0.076  1.00  0.00           N  
HETATM   13  C10 UNL     1       4.583  -2.381  -0.838  1.00  0.00           C  
HETATM   14  O2  UNL     1       3.974  -3.462  -1.031  1.00  0.00           O  
HETATM   15  O3  UNL     1       5.867  -2.126  -1.300  1.00  0.00           O  
HETATM   16  C11 UNL     1      -1.790   2.814  -1.447  1.00  0.00           C  
HETATM   17  O4  UNL     1      -0.822   3.569  -1.307  1.00  0.00           O  
HETATM   18  O5  UNL     1      -2.926   3.237  -2.078  1.00  0.00           O  
HETATM   19  H1  UNL     1      -4.668  -1.555   0.968  1.00  0.00           H  
HETATM   20  H2  UNL     1      -4.324  -0.062   2.003  1.00  0.00           H  
HETATM   21  H3  UNL     1      -5.166   0.139   0.438  1.00  0.00           H  
HETATM   22  H4  UNL     1      -3.275  -0.933  -0.719  1.00  0.00           H  
HETATM   23  H5  UNL     1      -1.383  -0.172   1.469  1.00  0.00           H  
HETATM   24  H6  UNL     1      -1.375  -1.614   0.370  1.00  0.00           H  
HETATM   25  H7  UNL     1      -2.465  -1.573   1.808  1.00  0.00           H  
HETATM   26  H8  UNL     1      -3.877   1.468  -0.678  1.00  0.00           H  
HETATM   27  H9  UNL     1      -2.922   1.737   0.810  1.00  0.00           H  
HETATM   28  H10 UNL     1      -1.790   0.787  -1.878  1.00  0.00           H  
HETATM   29  H11 UNL     1      -0.254   1.632   0.583  1.00  0.00           H  
HETATM   30  H12 UNL     1       2.227   0.920   0.060  1.00  0.00           H  
HETATM   31  H13 UNL     1       1.514  -0.448   0.951  1.00  0.00           H  
HETATM   32  H14 UNL     1       2.763  -0.675  -1.800  1.00  0.00           H  
HETATM   33  H15 UNL     1       2.014  -2.011  -0.855  1.00  0.00           H  
HETATM   34  H16 UNL     1       3.676  -1.749   0.938  1.00  0.00           H  
HETATM   35  H17 UNL     1       4.252   0.681  -0.395  1.00  0.00           H  
HETATM   36  H18 UNL     1       4.915   0.032   1.076  1.00  0.00           H  
HETATM   37  H19 UNL     1       6.019  -1.232  -1.751  1.00  0.00           H  
HETATM   38  H20 UNL     1      -3.573   3.915  -1.680  1.00  0.00           H  
CONECT    1    2   19   20   21
CONECT    2    3    4   22
CONECT    3   23   24   25
CONECT    4    5   26   27
CONECT    5    6   16   28
CONECT    6    7   29
CONECT    7    8    8    9
CONECT    9   10   30   31
CONECT   10   11   32   33
CONECT   11   12   13   34
CONECT   12   35   36
CONECT   13   14   14   15
CONECT   15   37
CONECT   16   17   17   18
CONECT   18   38
END

HMDB0011171
     RDKit          3D
gamma-Glutamylleucine
 38 37  0  0  0  0  0  0  0  0999 V2000
   -4.4365   -0.4895    0.9861 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.1085   -0.3327    0.1969 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0008   -0.9279    0.9909 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9422    1.1077   -0.1414 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7254    1.4224   -0.9259 C   0  0  2  0  0  0  0  0  0  0  0  0
   -0.4883    1.1236   -0.2965 N   0  0  0  0  0  0  0  0  0  0  0  0
    0.4447    0.1955   -0.8107 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.2591   -0.4492   -1.8755 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.7094   -0.0466   -0.0779 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5667   -1.0601   -0.7773 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.8540   -1.3303   -0.0645 C   0  0  2  0  0  0  0  0  0  0  0  0
    4.6760   -0.1495    0.0758 N   0  0  0  0  0  0  0  0  0  0  0  0
    4.5825   -2.3809   -0.8382 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9738   -3.4621   -1.0308 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.8668   -2.1265   -1.2998 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7896    2.8136   -1.4474 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8220    3.5690   -1.3065 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9258    3.2370   -2.0783 O   0  0  0  0  0  0  0  0  0  0  0  0
   -4.6677   -1.5549    0.9684 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3239   -0.0615    2.0033 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.1665    0.1391    0.4383 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2749   -0.9334   -0.7194 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3827   -0.1721    1.4687 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3754   -1.6145    0.3705 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4646   -1.5729    1.8080 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8774    1.4682   -0.6776 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9225    1.7371    0.8103 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7903    0.7873   -1.8781 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2542    1.6324    0.5829 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.2268    0.9195    0.0601 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.5137   -0.4479    0.9514 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.7629   -0.6754   -1.8000 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.0141   -2.0111   -0.8547 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.6758   -1.7487    0.9378 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.2525    0.6806   -0.3949 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.9145    0.0322    1.0758 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.0192   -1.2324   -1.7512 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5735    3.9150   -1.6798 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  1  0
  2  4  1  0
  4  5  1  0
  5  6  1  0
  6  7  1  0
  7  8  2  0
  7  9  1  0
  9 10  1  0
 10 11  1  0
 11 12  1  0
 11 13  1  0
 13 14  2  0
 13 15  1  0
  5 16  1  0
 16 17  2  0
 16 18  1  0
  1 19  1  0
  1 20  1  0
  1 21  1  0
  2 22  1  0
  3 23  1  0
  3 24  1  0
  3 25  1  0
  4 26  1  0
  4 27  1  0
  5 28  1  6
  6 29  1  0
  9 30  1  0
  9 31  1  0
 10 32  1  0
 10 33  1  0
 11 34  1  1
 12 35  1  0
 12 36  1  0
 15 37  1  0
 18 38  1  0
M  END

Synonyms

Value	Source
L-gamma-Glu-L-leu	ChEBI
L-g-Glu-L-leu	Generator
L-Γ-glu-L-leu	Generator
g-Glutamylleucine	Generator
Γ-glutamylleucine	Generator
Γ-glu-leu	HMDB
Γ-L-glu-L-leu	HMDB
Γ-L-glutamyl-L-leucine	HMDB
L-Γ-glutamyl-L-leucine	HMDB
N-Γ-glutamylleucine	HMDB
N-L-Γ-glutamylleucine	HMDB
N-L-Γ-glutamyl-L-leucine	HMDB
gamma-Glu-leu	HMDB
gamma-L-Glu-L-leu	HMDB
gamma-L-Glutamyl-L-leucine	HMDB
L-gamma-Glutamyl-L-leucine	HMDB
N-L-gamma-Glutamylleucine	HMDB
N-L-gamma-Glutamyl-L-leucine	HMDB
g-L-Glutamyl-L-leucine	HMDB
gamma-Glutamyl-leucine	HMDB
N-Γ-L-glutamyl-L-leucine	HMDB
N-gamma-Glutamylleucine	HMDB
N-gamma-L-Glutamyl-L-leucine	HMDB
g-Glu-leu	HMDB
gamma-Glutamylleucine	HMDB, MeSH

Molecular Formula

C₁₁H₂₀N₂O₅

Average Mass

260.2869

Monoisotopic Mass

260.13722176

IUPAC Name

(2S)-2-[(4S)-4-amino-4-carboxybutanamido]-4-methylpentanoic acid

Traditional Name

(2S)-2-[(4S)-4-amino-4-carboxybutanamido]-4-methylpentanoic acid

CAS Registry Number

Not Available

SMILES

CC(C)C[C@H](NC(=O)CC[C@H](N)C(O)=O)C(O)=O

InChI Identifier

InChI=1S/C11H20N2O5/c1-6(2)5-8(11(17)18)13-9(14)4-3-7(12)10(15)16/h6-8H,3-5,12H2,1-2H3,(H,13,14)(H,15,16)(H,17,18)/t7-,8-/m0/s1

InChI Key

MYFMARDICOWMQP-YUMQZZPRSA-N

Chemical Taxonomy

Functional Ontology

Physical Properties

Spectra

Spectrum Type	Description	Splash Key	Deposition Date	View
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive	Not Available	2021-10-12	View Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive	Not Available	2021-10-12	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - 35V, Positive	splash10-001r-9700000000-ab8893b60e98e1001ce4	2021-09-20	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - 35V, Negative	splash10-003r-0910000000-aabd82b48efea4e12f3f	2021-09-20	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 10V, Positive	splash10-00lr-2790000000-5c22f609f3419b66f92c	2016-06-03	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 20V, Positive	splash10-00lr-5920000000-c6ba6e3d51cd69c276b9	2016-06-03	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 40V, Positive	splash10-0a59-9300000000-b9930e2710d2f35bd3a9	2016-06-03	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 10V, Negative	splash10-0a4i-0390000000-3f84380e6a3d8cd32665	2016-08-03	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 20V, Negative	splash10-05nb-2960000000-9496cdad8fb51a2cf83a	2016-08-03	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 40V, Negative	splash10-008c-9400000000-a22f3c19c909bd949fb2	2016-08-03	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 10V, Positive	splash10-03xr-0290000000-bc2325e96da07defc0e3	2021-09-22	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 20V, Positive	splash10-001i-9500000000-1ff58fb786217f5dab60	2021-09-22	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 40V, Positive	splash10-053r-9000000000-a2e54d332ec42ec1dc2d	2021-09-22	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 10V, Negative	splash10-0006-0290000000-7c126c4b070de4bd4070	2021-09-23	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 20V, Negative	splash10-001i-1920000000-c5a4a154fcf2902b660f	2021-09-23	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 40V, Negative	splash10-0006-9500000000-39be620cfa483376cf2d	2021-09-23	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 100 MHz, D₂O, predicted)		2021-09-25	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, D₂O, predicted)		2021-09-25	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 1000 MHz, D₂O, predicted)		2021-09-25	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, D₂O, predicted)		2021-09-25	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 200 MHz, D₂O, predicted)		2021-09-25	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, D₂O, predicted)		2021-09-25	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 300 MHz, D₂O, predicted)		2021-09-25	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, D₂O, predicted)		2021-09-25	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 400 MHz, D₂O, predicted)		2021-09-25	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, D₂O, predicted)		2021-09-25	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 500 MHz, D₂O, predicted)		2021-09-25	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, D₂O, predicted)		2021-09-25	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 600 MHz, D₂O, predicted)		2021-09-25	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, D₂O, predicted)		2021-09-25	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 700 MHz, D₂O, predicted)		2021-09-25	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, D₂O, predicted)		2021-09-25	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 800 MHz, D₂O, predicted)		2021-09-25	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, D₂O, predicted)		2021-09-25	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 900 MHz, D₂O, predicted)		2021-09-25	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, D₂O, predicted)		2021-09-25	View Spectrum

Biological Properties

Human Proteins and Enzymes

Human Pathways

Metabolic Reactions

Health Effects and Bioactivity

Microbial Sources

Exposure Sources

Host Biospecimen and Location

External Links

References

Showing metabocard for gamma-Glutamylleucine (MMDBc0000446)

MOL for #<Metabolite:0x00007fb808d18bf8>

3D MOL for #<Metabolite:0x00007fb808d18bf8>

3D SDF for #<Metabolite:0x00007fb808d18bf8>

3D-SDF for #<Metabolite:0x00007fb808d18bf8>

PDB for #<Metabolite:0x00007fb808d18bf8>

3D PDB for #<Metabolite:0x00007fb808d18bf8>

SMILES for #<Metabolite:0x00007fb808d18bf8>

INCHI for #<Metabolite:0x00007fb808d18bf8>

Structure for #<Metabolite:0x00007fb808d18bf8>

3D Structure for #<Metabolite:0x00007fb808d18bf8>