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Record Information
Version1.0
StatusDetected and Quantified
Creation Date2020-12-10 18:50:34 UTC
Update Date2024-04-30 19:33:09 UTC
Metabolite IDMMDBc0000588
Metabolite Identification
Common Name2-Hydroxymyristic acid
Description2-Hydroxymyristic acid is an analog of myristic acid that becomes metabolically activated in cells to form 2-hydroxymyristoyl-CoA, a potent inhibitor of myristoyl-CoA:protein N-myristoyltransferase, the enzyme that catalyzes protein N-myristoylation. Treatment of T cells with 2-hydroxymyristic acid inhibits the myristoylation and alters the stability of p56lck. (PMID 8103677 ).
Structure
Synonyms
Molecular FormulaC14H28O3
Average Mass244.3703
Monoisotopic Mass244.203844762
IUPAC Name2-hydroxytetradecanoic acid
Traditional Name2-hydroxymyristic acid
CAS Registry NumberNot Available
SMILES
CCCCCCCCCCCCC(O)C(O)=O
InChI Identifier
InChI=1S/C14H28O3/c1-2-3-4-5-6-7-8-9-10-11-12-13(15)14(16)17/h13,15H,2-12H2,1H3,(H,16,17)
InChI KeyJYZJYKOZGGEXSX-UHFFFAOYSA-N