Record Information
Version1.0
StatusDetected and Quantified
Creation Date2020-12-10 23:04:54 UTC
Update Date2024-04-30 19:33:47 UTC
Metabolite IDMMDBc0000837
Metabolite Identification
Common NameO-Sulfo-L-tyrosine
DescriptionO-Sulfotyrosine belongs to the class of organic compounds known as phenylalanine and derivatives. Phenylalanine and derivatives are compounds containing phenylalanine or a derivative thereof resulting from a reaction of phenylalanine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom. O-Sulfotyrosine has been identified as a potential plasma biomarker of reduced kidney function in early chronic kidney disease (CKD), end stage renal disease (ESRD), and hemodialytic clearance (PMID: 31048706 ). Human plasma levels of O-sulfotyrosine were reported to be influenced by genetic variants in the gene ARSA which codes for the enzyme arylsulfatase A (PMID: 24816252 ).
Structure
Synonyms
ValueSource
(2S)-2-Amino-3-[4-(sulfooxy)phenyl]propanoic acidChEBI
(2S)-2-Azanyl-3-(4-sulfooxyphenyl)propanoic acidChEBI
L-Tyrosine O-sulfateChEBI
O-SulfO-L-tyrosineChEBI
SulfotyrosineChEBI
Tyrosine O-sulfateChEBI
Tyrosine sulfateChEBI
(2S)-2-Amino-3-[4-(sulfooxy)phenyl]propanoateGenerator
(2S)-2-Amino-3-[4-(sulphooxy)phenyl]propanoateGenerator
(2S)-2-Amino-3-[4-(sulphooxy)phenyl]propanoic acidGenerator
(2S)-2-Azanyl-3-(4-sulfooxyphenyl)propanoateGenerator
(2S)-2-Azanyl-3-(4-sulphooxyphenyl)propanoateGenerator
(2S)-2-Azanyl-3-(4-sulphooxyphenyl)propanoic acidGenerator
L-Tyrosine O-sulfuric acidGenerator
L-Tyrosine O-sulphateGenerator
L-Tyrosine O-sulphuric acidGenerator
O-SulphO-L-tyrosineGenerator
SulphotyrosineGenerator
Tyrosine O-sulfuric acidGenerator
Tyrosine O-sulphateGenerator
Tyrosine O-sulphuric acidGenerator
Tyrosine sulfuric acidGenerator
Tyrosine sulphateGenerator
Tyrosine sulphuric acidGenerator
O(4')-SulphO-L-tyrosineGenerator
O-DecasulfateMeSH, HMDB
O-SulfotyrosineHMDB
O-SulphotyrosineGenerator
Molecular FormulaC9H11NO6S
Average Mass261.252
Monoisotopic Mass261.030707779
IUPAC Name(2S)-2-amino-3-[4-(sulfooxy)phenyl]propanoic acid
Traditional Name(2S)-2-amino-3-[4-(sulfooxy)phenyl]propanoic acid
CAS Registry NumberNot Available
SMILES
N[C@@H](CC1=CC=C(OS(O)(=O)=O)C=C1)C(O)=O
InChI Identifier
InChI=1S/C9H11NO6S/c10-8(9(11)12)5-6-1-3-7(4-2-6)16-17(13,14)15/h1-4,8H,5,10H2,(H,11,12)(H,13,14,15)/t8-/m0/s1
InChI KeyCIQHWLTYGMYQQR-QMMMGPOBSA-N