MiMeDB: Showing metabocard for N-acetyl-3-amino-3,6-dideoxy-d-galactose (MMDBc0001232)

Record Information

Version

1.0

Status

Detected and Quantified

Creation Date

2021-05-14 19:32:39 UTC

Update Date

2022-08-31 06:17:48 UTC

Metabolite ID

MMDBc0001232

Metabolite Identification

Common Name

N-acetyl-3-amino-3,6-dideoxy-d-galactose

Description

SCHEMBL7149939 belongs to the class of organic compounds known as monosaccharides. Monosaccharides are compounds containing one carbohydrate unit not glycosidically linked to another such unit, and no set of two or more glycosidically linked carbohydrate units. Monosaccharides have the general formula CnH2nOn. Based on a literature review very few articles have been published on SCHEMBL7149939.

Structure

MOL SDF PDB SMILES InChI


  Mrv1652305142121322D          

 18 17  0  0  1  0            999 V2000
    5.3625   -0.7145    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.6500   -2.8579    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0625   -0.7145    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.5375   -0.7145    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    2.0625   -2.1434    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8875   -0.7145    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.3000   -1.4289    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    4.1250   -1.4289    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    2.8875   -2.1434    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    1.6500   -0.0000    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.1250    0.0000    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.6500   -1.4289    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.3000   -0.0000    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.5375   -2.1434    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.9500   -1.4289    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.4750   -1.4289    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.7125   -0.7145    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.7125   -2.1434    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
  4  1  1  0  0  0  0
  5  2  1  4  0  0  0
  6  3  1  0  0  0  0
  7  6  1  0  0  0  0
  8  4  1  0  0  0  0
  8  7  1  0  0  0  0
  9  5  2  0  0  0  0
  7  9  1  1  0  0  0
 10  3  2  0  0  0  0
  4 11  1  1  0  0  0
 12  5  1  0  0  0  0
  6 13  1  1  0  0  0
  8 14  1  6  0  0  0
  4 15  1  1  0  0  0
  6 16  1  1  0  0  0
  7 17  1  1  0  0  0
  8 18  1  1  0  0  0
M  END
> <DATABASE_ID>
MMDBc0001232

> <DATABASE_NAME>
MIME

> <SMILES>
[H][C@](C)(O)[C@]([H])(O)[C@]([H])(N=C(C)O)[C@@]([H])(O)C=O

> <INCHI_IDENTIFIER>
InChI=1S/C8H15NO5/c1-4(11)8(14)7(6(13)3-10)9-5(2)12/h3-4,6-8,11,13-14H,1-2H3,(H,9,12)/t4-,6+,7-,8+/m1/s1

> <INCHI_KEY>
NGULQTOJUIQGLA-APTPUMFKSA-N

> <FORMULA>
C8H15NO5

> <MOLECULAR_WEIGHT>
205.21

> <EXACT_MASS>
205.095022587

> <JCHEM_ACCEPTOR_COUNT>
6

> <JCHEM_ATOM_COUNT>
29

> <JCHEM_AVERAGE_POLARIZABILITY>
19.617105698870976

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
4

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
N-[(2R,3S,4R,5R)-2,4,5-trihydroxy-1-oxohexan-3-yl]ethanimidic acid

> <ALOGPS_LOGP>
-1.39

> <JCHEM_LOGP>
-1.9898816630000005

> <ALOGPS_LOGS>
-0.98

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
0

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA>
12.793295410806909

> <JCHEM_PKA_STRONGEST_ACIDIC>
5.878059376625606

> <JCHEM_PKA_STRONGEST_BASIC>
2.2487228123046528

> <JCHEM_POLAR_SURFACE_AREA>
110.35000000000001

> <JCHEM_REFRACTIVITY>
47.4249

> <JCHEM_ROTATABLE_BOND_COUNT>
5

> <JCHEM_RULE_OF_FIVE>
1

> <ALOGPS_SOLUBILITY>
2.15e+01 g/l

> <JCHEM_TRADITIONAL_IUPAC>
N-[(2R,3S,4R,5R)-2,4,5-trihydroxy-1-oxohexan-3-yl]ethanimidic acid

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 14-MAY-21   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   14-MAY-21         0                                  
HETATM    1  C   UNK     0      10.010  -1.334   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0       3.080  -5.335   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0       3.850  -1.334   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0       8.470  -1.334   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0       3.850  -4.001   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0       5.390  -1.334   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0       6.160  -2.667   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0       7.700  -2.667   0.000  0.00  0.00           C+0
HETATM    9  N   UNK     0       5.390  -4.001   0.000  0.00  0.00           N+0
HETATM   10  O   UNK     0       3.080  -0.000   0.000  0.00  0.00           O+0
HETATM   11  O   UNK     0       7.700   0.000   0.000  0.00  0.00           O+0
HETATM   12  O   UNK     0       3.080  -2.667   0.000  0.00  0.00           O+0
HETATM   13  O   UNK     0       6.160  -0.000   0.000  0.00  0.00           O+0
HETATM   14  O   UNK     0       8.470  -4.001   0.000  0.00  0.00           O+0
HETATM   15  H   UNK     0       9.240  -2.667   0.000  0.00  0.00           H+0
HETATM   16  H   UNK     0       4.620  -2.667   0.000  0.00  0.00           H+0
HETATM   17  H   UNK     0       6.930  -1.334   0.000  0.00  0.00           H+0
HETATM   18  H   UNK     0       6.930  -4.001   0.000  0.00  0.00           H+0
CONECT    1    4                                                            
CONECT    2    5                                                            
CONECT    3    6   10                                                       
CONECT    4    1    8   11   15                                             
CONECT    5    2    9   12                                                  
CONECT    6    3    7   13   16                                             
CONECT    7    6    8    9   17                                             
CONECT    8    4    7   14   18                                             
CONECT    9    5    7                                                       
CONECT   10    3                                                            
CONECT   11    4                                                            
CONECT   12    5                                                            
CONECT   13    6                                                            
CONECT   14    8                                                            
CONECT   15    4                                                            
CONECT   16    6                                                            
CONECT   17    7                                                            
CONECT   18    8                                                            
MASTER        0    0    0    0    0    0    0    0   18    0   34    0
END

Synonyms

Not Available

Molecular Formula

C₈H₁₅NO₅

Average Mass

205.21

Monoisotopic Mass

205.095022587

IUPAC Name

N-[(2R,3S,4R,5R)-2,4,5-trihydroxy-1-oxohexan-3-yl]ethanimidic acid

Traditional Name

N-[(2R,3S,4R,5R)-2,4,5-trihydroxy-1-oxohexan-3-yl]ethanimidic acid

CAS Registry Number

Not Available

SMILES

[H][C@](C)(O)[C@]([H])(O)[C@]([H])(N=C(C)O)[C@@]([H])(O)C=O

InChI Identifier

InChI=1S/C8H15NO5/c1-4(11)8(14)7(6(13)3-10)9-5(2)12/h3-4,6-8,11,13-14H,1-2H3,(H,9,12)/t4-,6+,7-,8+/m1/s1

InChI Key

NGULQTOJUIQGLA-APTPUMFKSA-N

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as monosaccharides. Monosaccharides are compounds containing one carbohydrate unit not glycosidically linked to another such unit, and no set of two or more glycosidically linked carbohydrate units. Monosaccharides have the general formula CnH2nOn.

Kingdom

Organic compounds

Super Class

Organic oxygen compounds

Class

Organooxygen compounds

Sub Class

Carbohydrates and carbohydrate conjugates

Direct Parent

Monosaccharides

Alternative Parents

Substituents

Monosaccharide
Alpha-hydroxyaldehyde
Acetamide
Carboxamide group
Secondary alcohol
Secondary carboxylic acid amide
Polyol
Carboxylic acid derivative
Aldehyde
Organonitrogen compound
Organic nitrogen compound
Alcohol
Carbonyl group
Organic oxide
Hydrocarbon derivative
Aliphatic acyclic compound

Molecular Framework

Aliphatic acyclic compounds

External Descriptors

Not Available

Functional Ontology

Not Available

Physical Properties

State

Expected Solid

Predicted Properties

Property	Value	Source
Water Solubility	21.5 g/L	ALOGPS
logP	-1.4	ALOGPS
logP	-2	ChemAxon
logS	-0.98	ALOGPS
pKa (Strongest Acidic)	5.88	ChemAxon
pKa (Strongest Basic)	2.25	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	6	ChemAxon
Hydrogen Donor Count	4	ChemAxon
Polar Surface Area	110.35 Å²	ChemAxon
Rotatable Bond Count	5	ChemAxon
Refractivity	47.42 m³·mol⁻¹	ChemAxon
Polarizability	19.62 Å³	ChemAxon
Number of Rings	0	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

Spectra

Not Available

Biological Properties

Cellular Locations

Not Available

Biospecimen Locations

Not Available

Tissue Locations

Not Available

Associated OMIM IDs

114500 (Colorectal cancer)
610247 (Eosinophilic esophagitis)

Human Proteins and Enzymes

Protein ID	Protein Name	Protein Type	Uniprot ID	Species

Human Pathways

Pathways

Name	SMPDB/PathBank

Metabolic Reactions

Not Available

Health Effects and Bioactivity

Health Outcome/Bioactivity	Metabolite Response/Effect	Evidence Type	Host and Biospecimen	Data Source	Reference

Microbial Sources

Superkingdom/Kingdom	Phylum	Total species	Hosts and Body Sites	Microbial Links
Bacteria	Proteobacteria	1		Metabolic reconstruction

Exposure Sources

Host Biospecimen and Location

Host and Biospecimen	Status	Mean	Std	Min	Max	Units	Age	Sex	Health Condition	Data Source	Reference

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FooDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

21376795

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

88100617

PDB ID

Not Available

ChEBI ID

Not Available

Food Biomarker Ontology

Not Available

References

Synthesis Reference

Not Available

General References

van Santen JA, Poynton EF, Iskakova D, McMann E, Alsup TA, Clark TN, Fergusson CH, Fewer DP, Hughes AH, McCadden CA, Parra J, Soldatou S, Rudolf JD, Janssen EM, Duncan KR, Linington RG: The Natural Products Atlas 2.0: a database of microbially-derived natural products. Nucleic Acids Res. 2022 Jan 7;50(D1):D1317-D1323. doi: 10.1093/nar/gkab941. [PubMed:34718710 ]

Showing metabocard for N-acetyl-3-amino-3,6-dideoxy-d-galactose (MMDBc0001232)

MOL for #<Metabolite:0x00007fdb4c0150c0>

3D MOL for #<Metabolite:0x00007fdb4c0150c0>

3D SDF for #<Metabolite:0x00007fdb4c0150c0>

3D-SDF for #<Metabolite:0x00007fdb4c0150c0>

PDB for #<Metabolite:0x00007fdb4c0150c0>

3D PDB for #<Metabolite:0x00007fdb4c0150c0>

SMILES for #<Metabolite:0x00007fdb4c0150c0>

INCHI for #<Metabolite:0x00007fdb4c0150c0>

Structure for #<Metabolite:0x00007fdb4c0150c0>

3D Structure for #<Metabolite:0x00007fdb4c0150c0>