Mrv1533004241505182D
30 34 0 0 0 0 999 V2000
3.4312 -3.5319 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
2.6062 -3.5319 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
2.1937 -2.8174 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
2.6062 -2.1030 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
1.3687 -2.8174 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
0.8838 -3.4849 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0
0.0992 -3.2299 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
0.0992 -2.4049 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-0.5683 -1.9200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-1.3529 -2.1750 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-1.8378 -1.5075 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0
-1.3529 -0.8401 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-1.5244 -0.0331 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-0.9113 0.5189 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-1.0829 1.3259 0.0000 Cl 0 0 0 0 0 0 0 0 0 0 0 0
-0.1267 0.2640 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
0.4864 0.8160 0.0000 Cl 0 0 0 0 0 0 0 0 0 0 0 0
0.0448 -0.5430 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-0.5683 -1.0950 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
0.8838 -2.1500 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
1.1387 -1.3654 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
0.6538 -0.6979 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
1.1387 -0.0305 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0
1.9233 -0.2854 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
2.6378 0.1271 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
3.3523 -0.2854 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
3.3523 -1.1104 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
4.0668 -1.5229 0.0000 Cl 0 0 0 0 0 0 0 0 0 0 0 0
2.6378 -1.5229 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
1.9233 -1.1104 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
1 2 1 0 0 0 0
2 3 1 0 0 0 0
3 4 2 0 0 0 0
3 5 1 0 0 0 0
5 6 1 0 0 0 0
6 7 1 0 0 0 0
7 8 2 0 0 0 0
8 9 1 0 0 0 0
9 10 2 0 0 0 0
10 11 1 0 0 0 0
11 12 1 0 0 0 0
12 13 2 0 0 0 0
13 14 1 0 0 0 0
14 15 1 0 0 0 0
14 16 2 0 0 0 0
16 17 1 0 0 0 0
16 18 1 0 0 0 0
18 19 2 0 0 0 0
9 19 1 0 0 0 0
12 19 1 0 0 0 0
8 20 1 0 0 0 0
5 20 2 0 0 0 0
20 21 1 0 0 0 0
21 22 2 0 0 0 0
22 23 1 0 0 0 0
23 24 1 0 0 0 0
24 25 2 0 0 0 0
25 26 1 0 0 0 0
26 27 2 0 0 0 0
27 28 1 0 0 0 0
27 29 1 0 0 0 0
29 30 2 0 0 0 0
21 30 1 0 0 0 0
24 30 1 0 0 0 0
M END
> <DATABASE_ID>
MMDBc0006436
> <DATABASE_NAME>
MIME
> <SMILES>
COC(=O)C1=C(C(=CN1)C1=CNC2=CC(Cl)=C(Cl)C=C12)C1=CNC2=CC=C(Cl)C=C12
> <INCHI_IDENTIFIER>
InChI=1S/C22H14Cl3N3O2/c1-30-22(29)21-20(14-8-26-18-3-2-10(23)4-11(14)18)15(9-28-21)13-7-27-19-6-17(25)16(24)5-12(13)19/h2-9,26-28H,1H3
> <INCHI_KEY>
HJXJUNZGSRTQEN-UHFFFAOYSA-N
> <FORMULA>
C22H14Cl3N3O2
> <MOLECULAR_WEIGHT>
458.72
> <EXACT_MASS>
457.0151598
> <JCHEM_ACCEPTOR_COUNT>
1
> <JCHEM_ATOM_COUNT>
44
> <JCHEM_AVERAGE_POLARIZABILITY>
44.09040727481354
> <JCHEM_BIOAVAILABILITY>
1
> <JCHEM_DONOR_COUNT>
3
> <JCHEM_FORMAL_CHARGE>
0
> <JCHEM_GHOSE_FILTER>
0
> <JCHEM_IUPAC>
methyl 3-(5-chloro-1H-indol-3-yl)-4-(5,6-dichloro-1H-indol-3-yl)-1H-pyrrole-2-carboxylate
> <ALOGPS_LOGP>
5.87
> <JCHEM_LOGP>
6.280716755333333
> <ALOGPS_LOGS>
-6.03
> <JCHEM_MDDR_LIKE_RULE>
0
> <JCHEM_NUMBER_OF_RINGS>
5
> <JCHEM_PHYSIOLOGICAL_CHARGE>
0
> <JCHEM_PKA>
15.2146962729237
> <JCHEM_PKA_STRONGEST_ACIDIC>
11.65264039864209
> <JCHEM_PKA_STRONGEST_BASIC>
-7.128669359018623
> <JCHEM_POLAR_SURFACE_AREA>
73.67
> <JCHEM_REFRACTIVITY>
119.57939999999999
> <JCHEM_ROTATABLE_BOND_COUNT>
3
> <JCHEM_RULE_OF_FIVE>
0
> <ALOGPS_SOLUBILITY>
4.30e-04 g/l
> <JCHEM_TRADITIONAL_IUPAC>
lynamicin B
> <JCHEM_VEBER_RULE>
0
$$$$