Mrv1652305152103012D
47 51 0 0 1 0 999 V2000
0.1002 -0.7763 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-0.1126 1.4941 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
5.5583 -1.7800 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
4.2081 2.1177 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
2.3049 0.2015 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
5.0182 -0.2209 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
9.6090 1.8059 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
8.7989 1.9618 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
2.5878 2.4296 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
3.3980 2.2736 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
9.8790 1.0264 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
6.9086 0.8704 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
3.3980 0.0909 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
8.5288 0.5586 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
1.5032 0.8958 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
0.3944 -0.0055 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
0.6975 1.3382 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
5.2883 -1.0005 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
8.2588 1.3382 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
7.4486 1.4941 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
6.0984 1.0264 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
3.1279 0.8704 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0
2.0477 1.8059 0.0000 C 0 0 1 0 0 0 0 0 0 0 0 0
4.2081 -0.0650 0.0000 C 0 0 1 0 0 0 0 0 0 0 0 0
5.8284 1.8059 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
5.0182 1.9618 0.0000 C 0 0 1 0 0 0 0 0 0 0 0 0
4.4782 1.3382 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0
6.3685 2.4296 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
3.6680 1.4941 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0
2.3178 1.0264 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0
4.7482 0.5586 0.0000 C 0 0 1 0 0 0 0 0 0 0 0 0
9.3390 0.4027 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0
-0.1260 0.6346 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
0.9676 0.5586 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
5.8284 -0.3768 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
4.7482 2.7414 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
6.0984 3.2091 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
1.2090 0.1250 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
1.2376 1.9618 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
4.4782 -0.8446 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
7.1786 2.2736 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
5.5583 0.4027 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
3.9381 0.7145 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0
1.5077 1.1823 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0
3.6680 -0.6887 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0
5.5583 2.5855 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0
5.2883 1.1823 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0
8 7 2 0 0 0 0
10 9 1 0 0 0 0
11 7 1 0 0 0 0
16 1 1 0 0 0 0
17 2 1 0 0 0 0
18 3 1 0 0 0 0
19 8 1 0 0 0 0
19 14 2 0 0 0 0
20 12 2 0 0 0 0
20 19 1 0 0 0 0
21 12 1 0 0 0 0
22 13 1 0 0 0 0
23 9 1 0 0 0 0
24 13 1 0 0 0 0
25 21 2 0 0 0 0
26 25 1 0 0 0 0
27 26 1 0 0 0 0
28 25 1 0 0 0 0
29 4 1 1 0 0 0
29 10 1 0 0 0 0
29 22 1 0 0 0 0
29 27 1 0 0 0 0
30 5 1 1 0 0 0
30 15 1 6 0 0 0
30 22 1 0 0 0 0
30 23 1 0 0 0 0
31 6 1 1 0 0 0
31 24 1 0 0 0 0
31 27 1 0 0 0 0
32 11 2 0 0 0 0
32 14 1 0 0 0 0
33 16 2 0 0 0 0
34 17 2 0 0 0 0
35 18 2 0 0 0 0
26 36 1 1 0 0 0
37 28 2 0 0 0 0
38 15 1 0 0 0 0
38 16 1 0 0 0 0
39 17 1 0 0 0 0
23 39 1 1 0 0 0
40 18 1 0 0 0 0
24 40 1 1 0 0 0
41 20 1 0 0 0 0
41 28 1 0 0 0 0
42 21 1 0 0 0 0
42 31 1 0 0 0 0
22 43 1 6 0 0 0
23 44 1 6 0 0 0
24 45 1 6 0 0 0
26 46 1 6 0 0 0
27 47 1 6 0 0 0
M END
> <DATABASE_ID>
MMDBc0008042
> <DATABASE_NAME>
MIME
> <SMILES>
[H][C@@]1(CC[C@@]2(C)[C@@]([H])(C[C@]([H])(OC(C)=O)[C@@]3(C)OC4=C(C(=O)OC(=C4)C4=CN=CC=C4)[C@]([H])(O)[C@]23[H])[C@]1(C)COC(C)=O)OC(C)=O
> <INCHI_IDENTIFIER>
InChI=1S/C31H37NO10/c1-16(33)38-15-30(5)22-13-24(40-18(3)35)31(6)27(29(22,4)10-9-23(30)39-17(2)34)26(36)25-21(42-31)12-20(41-28(25)37)19-8-7-11-32-14-19/h7-8,11-12,14,22-24,26-27,36H,9-10,13,15H2,1-6H3/t22-,23+,24+,26+,27-,29+,30+,31-/m1/s1
> <INCHI_KEY>
PMMQOFWSZRQWEV-RVTXXDJVSA-N
> <FORMULA>
C31H37NO10
> <MOLECULAR_WEIGHT>
583.634
> <EXACT_MASS>
583.241746395
> <JCHEM_ACCEPTOR_COUNT>
7
> <JCHEM_ATOM_COUNT>
79
> <JCHEM_AVERAGE_POLARIZABILITY>
61.36128760154838
> <JCHEM_BIOAVAILABILITY>
1
> <JCHEM_DONOR_COUNT>
1
> <JCHEM_FORMAL_CHARGE>
0
> <JCHEM_GHOSE_FILTER>
0
> <JCHEM_IUPAC>
[(5aS,6S,7aR,8R,9S,11aS,11bS,12R)-6,9-bis(acetyloxy)-12-hydroxy-5a,8,11a-trimethyl-1-oxo-3-(pyridin-3-yl)-1,5a,6,7,7a,8,9,10,11,11a,11b,12-dodecahydro-2,5-dioxatetraphen-8-yl]methyl acetate
> <ALOGPS_LOGP>
3.14
> <JCHEM_LOGP>
0.9063434059999995
> <ALOGPS_LOGS>
-4.38
> <JCHEM_MDDR_LIKE_RULE>
1
> <JCHEM_NUMBER_OF_RINGS>
5
> <JCHEM_PHYSIOLOGICAL_CHARGE>
0
> <JCHEM_PKA_STRONGEST_ACIDIC>
13.839017422883696
> <JCHEM_PKA_STRONGEST_BASIC>
4.206336732053929
> <JCHEM_POLAR_SURFACE_AREA>
147.54999999999998
> <JCHEM_REFRACTIVITY>
147.8618
> <JCHEM_ROTATABLE_BOND_COUNT>
8
> <JCHEM_RULE_OF_FIVE>
0
> <ALOGPS_SOLUBILITY>
2.44e-02 g/l
> <JCHEM_TRADITIONAL_IUPAC>
[(5aS,6S,7aR,8R,9S,11aS,11bS,12R)-6,9-bis(acetyloxy)-12-hydroxy-5a,8,11a-trimethyl-1-oxo-3-(pyridin-3-yl)-6,7,7a,9,10,11,11b,12-octahydro-2,5-dioxatetraphen-8-yl]methyl acetate
> <JCHEM_VEBER_RULE>
0
$$$$