MiMeDB: Showing metabocard for Fredericamycin C (MMDBc0012092)

Record Information

Version

1.0

Status

Detected and Quantified

Creation Date

2021-05-15 03:43:56 UTC

Update Date

2022-08-31 06:33:58 UTC

Metabolite ID

MMDBc0012092

Metabolite Identification

Common Name

Fredericamycin C

Description

Fredericamycin C belongs to the class of organic compounds known as tetracenequinones. These are polyaromatic hydrocarbon derivatives containing a tetracyclic cycle made up of four linearly fused benzene rings, one of which bears two ketone groups at position 1 and 4. Based on a literature review very few articles have been published on Fredericamycin C.

Structure

MOL SDF PDB SMILES InChI


  Mrv1652305152105432D          

 46 50  0  0  0  0            999 V2000
   10.8987   -1.3970    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7834   -2.0835    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   10.1061   -1.6258    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    9.5116   -1.0538    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.7190   -1.2826    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.1245   -0.7106    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7558   -2.4267    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9632   -2.6555    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7466   -1.3970    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.7374   -0.3674    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5945   -0.2530    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.9540   -1.6258    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.9448   -0.5962    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.3319   -0.9394    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3687   -2.0835    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.1982   -0.0242    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7926   -1.0538    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3595   -1.0538    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.3503   -0.0242    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5669   -1.2826    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7926   -0.5962    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5945   -1.3970    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.9816   -1.7403    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1797   -0.9394    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5761   -2.3123    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1982   -1.6258    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.5576   -0.2530    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.9724   -0.7106    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5853   -0.3674    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1890   -1.9691    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.5484    0.7767    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.1337   -1.7403    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.3963    0.7767    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.3779   -3.1131    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3963   -2.4267    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.9632    0.3191    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.1705    0.0903    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.7834    0.4335    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.9908   -2.7699    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.9540    1.3487    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.3411    1.0055    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5853   -1.2826    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    9.9079   -2.4267    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    9.7098   -0.2530    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    8.5208   -2.0835    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    8.3227    0.0903    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
  3  1  1  0  0  0  0
  4  3  2  0  0  0  0
  5  4  1  0  0  0  0
  6  5  2  0  0  0  0
  8  7  1  0  0  0  0
 12  7  1  0  0  0  0
 12  9  2  0  0  0  0
 13  9  1  0  0  0  0
 13 10  1  0  0  0  0
 14  6  1  0  0  0  0
 14 10  1  0  0  0  0
 15  8  1  0  0  0  0
 16 11  2  0  0  0  0
 17 11  1  0  0  0  0
 18 12  1  0  0  0  0
 19 13  2  0  0  0  0
 20 15  1  0  0  0  0
 20 18  1  0  0  0  0
 21 16  1  0  0  0  0
 22 21  2  0  0  0  0
 24 23  2  0  0  0  0
 25 15  2  0  0  0  0
 25 23  1  0  0  0  0
 26 17  2  0  0  0  0
 26 22  1  0  0  0  0
 27 18  2  0  0  0  0
 27 19  1  0  0  0  0
 28 20  2  0  0  0  0
 28 24  1  0  0  0  0
 29 21  1  0  0  0  0
 29 24  1  0  0  0  0
 30 22  1  0  0  0  0
 30 23  1  0  0  0  0
 31 19  1  0  0  0  0
 32 14  2  0  0  0  0
 33 16  1  0  0  0  0
 34 25  1  0  0  0  0
 35 26  1  0  0  0  0
 36 27  1  0  0  0  0
 37 28  1  0  0  0  0
 38 29  2  0  0  0  0
 39 30  2  0  0  0  0
 40 31  2  0  0  0  0
 41 31  1  0  0  0  0
 42  2  1  0  0  0  0
 42 17  1  0  0  0  0
 43  3  1  0  0  0  0
 44  4  1  0  0  0  0
 45  5  1  0  0  0  0
 46  6  1  0  0  0  0
M  END


  Mrv1652305152105432D          

 46 50  0  0  0  0            999 V2000
   10.8987   -1.3970    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7834   -2.0835    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   10.1061   -1.6258    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    9.5116   -1.0538    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.7190   -1.2826    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.1245   -0.7106    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7558   -2.4267    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9632   -2.6555    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7466   -1.3970    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.7374   -0.3674    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5945   -0.2530    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.9540   -1.6258    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.9448   -0.5962    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.3319   -0.9394    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3687   -2.0835    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.1982   -0.0242    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7926   -1.0538    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3595   -1.0538    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.3503   -0.0242    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5669   -1.2826    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7926   -0.5962    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5945   -1.3970    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.9816   -1.7403    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1797   -0.9394    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5761   -2.3123    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1982   -1.6258    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.5576   -0.2530    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.9724   -0.7106    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5853   -0.3674    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1890   -1.9691    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.5484    0.7767    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.1337   -1.7403    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.3963    0.7767    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.3779   -3.1131    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3963   -2.4267    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.9632    0.3191    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.1705    0.0903    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.7834    0.4335    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.9908   -2.7699    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.9540    1.3487    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.3411    1.0055    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5853   -1.2826    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    9.9079   -2.4267    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    9.7098   -0.2530    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    8.5208   -2.0835    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    8.3227    0.0903    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
  3  1  1  0  0  0  0
  4  3  2  0  0  0  0
  5  4  1  0  0  0  0
  6  5  2  0  0  0  0
  8  7  1  0  0  0  0
 12  7  1  0  0  0  0
 12  9  2  0  0  0  0
 13  9  1  0  0  0  0
 13 10  1  0  0  0  0
 14  6  1  0  0  0  0
 14 10  1  0  0  0  0
 15  8  1  0  0  0  0
 16 11  2  0  0  0  0
 17 11  1  0  0  0  0
 18 12  1  0  0  0  0
 19 13  2  0  0  0  0
 20 15  1  0  0  0  0
 20 18  1  0  0  0  0
 21 16  1  0  0  0  0
 22 21  2  0  0  0  0
 24 23  2  0  0  0  0
 25 15  2  0  0  0  0
 25 23  1  0  0  0  0
 26 17  2  0  0  0  0
 26 22  1  0  0  0  0
 27 18  2  0  0  0  0
 27 19  1  0  0  0  0
 28 20  2  0  0  0  0
 28 24  1  0  0  0  0
 29 21  1  0  0  0  0
 29 24  1  0  0  0  0
 30 22  1  0  0  0  0
 30 23  1  0  0  0  0
 31 19  1  0  0  0  0
 32 14  2  0  0  0  0
 33 16  1  0  0  0  0
 34 25  1  0  0  0  0
 35 26  1  0  0  0  0
 36 27  1  0  0  0  0
 37 28  1  0  0  0  0
 38 29  2  0  0  0  0
 39 30  2  0  0  0  0
 40 31  2  0  0  0  0
 41 31  1  0  0  0  0
 42  2  1  0  0  0  0
 42 17  1  0  0  0  0
 43  3  1  0  0  0  0
 44  4  1  0  0  0  0
 45  5  1  0  0  0  0
 46  6  1  0  0  0  0
M  END
> <DATABASE_ID>
MMDBc0012092

> <DATABASE_NAME>
MIME

> <SMILES>
[H]\C(C)=C(\[H])/C(/[H])=C(\[H])C(=O)CC1=C(C(O)=O)C(O)=C2C(CCC3=C(O)C4=C(C(O)=C23)C(=O)C2=C(C(O)=C(OC)C=C2O)C4=O)=C1

> <INCHI_IDENTIFIER>
InChI=1S/C31H24O11/c1-3-4-5-6-14(32)10-13-9-12-7-8-15-20(18(12)27(36)19(13)31(40)41)28(37)24-23(25(15)34)30(39)22-21(29(24)38)16(33)11-17(42-2)26(22)35/h3-6,9,11,33-37H,7-8,10H2,1-2H3,(H,40,41)/b4-3+,6-5+

> <INCHI_KEY>
LKUAAWSFMBXAPQ-VNKDHWASSA-N

> <FORMULA>
C31H24O11

> <MOLECULAR_WEIGHT>
572.522

> <EXACT_MASS>
572.131861593

> <JCHEM_ACCEPTOR_COUNT>
11

> <JCHEM_ATOM_COUNT>
66

> <JCHEM_AVERAGE_POLARIZABILITY>
58.38365923936974

> <JCHEM_BIOAVAILABILITY>
0

> <JCHEM_DONOR_COUNT>
6

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
2,5,13,17,20-pentahydroxy-18-methoxy-15,22-dioxo-7-[(3E,5E)-2-oxohepta-3,5-dien-1-yl]pentacyclo[12.8.0.0^{3,12}.0^{4,9}.0^{16,21}]docosa-1,3(12),4,6,8,13,16(21),17,19-nonaene-6-carboxylic acid

> <ALOGPS_LOGP>
3.95

> <JCHEM_LOGP>
7.998650833666666

> <ALOGPS_LOGS>
-4.14

> <JCHEM_MDDR_LIKE_RULE>
1

> <JCHEM_NUMBER_OF_RINGS>
5

> <JCHEM_PHYSIOLOGICAL_CHARGE>
-1

> <JCHEM_PKA>
8.12900399793921

> <JCHEM_PKA_STRONGEST_ACIDIC>
2.672058568553839

> <JCHEM_PKA_STRONGEST_BASIC>
-4.67480936186004

> <JCHEM_POLAR_SURFACE_AREA>
198.89

> <JCHEM_REFRACTIVITY>
153.6898

> <JCHEM_ROTATABLE_BOND_COUNT>
6

> <JCHEM_RULE_OF_FIVE>
0

> <ALOGPS_SOLUBILITY>
4.18e-02 g/l

> <JCHEM_TRADITIONAL_IUPAC>
2,5,13,17,20-pentahydroxy-18-methoxy-15,22-dioxo-7-[(3E,5E)-2-oxohepta-3,5-dien-1-yl]pentacyclo[12.8.0.0^{3,12}.0^{4,9}.0^{16,21}]docosa-1,3(12),4,6,8,13,16(21),17,19-nonaene-6-carboxylic acid

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 15-MAY-21   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   15-MAY-21         0                                  
HETATM    1  C   UNK     0      20.344  -2.608   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0      -3.329  -3.889   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0      18.865  -3.035   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0      17.755  -1.967   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0      16.275  -2.394   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0      15.166  -1.326   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0       8.878  -4.530   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0       7.398  -4.957   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0      10.727  -2.608   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0      12.576  -0.686   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0      -1.110  -0.472   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0       9.247  -3.035   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0      11.097  -1.113   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0      13.686  -1.754   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0       6.288  -3.889   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0       0.370  -0.045   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0      -1.480  -1.967   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0       8.138  -1.967   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0       9.987  -0.045   0.000  0.00  0.00           C+0
HETATM   20  C   UNK     0       6.658  -2.394   0.000  0.00  0.00           C+0
HETATM   21  C   UNK     0       1.480  -1.113   0.000  0.00  0.00           C+0
HETATM   22  C   UNK     0       1.110  -2.608   0.000  0.00  0.00           C+0
HETATM   23  C   UNK     0       3.699  -3.248   0.000  0.00  0.00           C+0
HETATM   24  C   UNK     0       4.069  -1.754   0.000  0.00  0.00           C+0
HETATM   25  C   UNK     0       4.809  -4.316   0.000  0.00  0.00           C+0
HETATM   26  C   UNK     0      -0.370  -3.035   0.000  0.00  0.00           C+0
HETATM   27  C   UNK     0       8.508  -0.472   0.000  0.00  0.00           C+0
HETATM   28  C   UNK     0       5.548  -1.326   0.000  0.00  0.00           C+0
HETATM   29  C   UNK     0       2.959  -0.686   0.000  0.00  0.00           C+0
HETATM   30  C   UNK     0       2.219  -3.676   0.000  0.00  0.00           C+0
HETATM   31  C   UNK     0      10.357   1.450   0.000  0.00  0.00           C+0
HETATM   32  O   UNK     0      13.316  -3.248   0.000  0.00  0.00           O+0
HETATM   33  O   UNK     0       0.740   1.450   0.000  0.00  0.00           O+0
HETATM   34  O   UNK     0       4.439  -5.811   0.000  0.00  0.00           O+0
HETATM   35  O   UNK     0      -0.740  -4.530   0.000  0.00  0.00           O+0
HETATM   36  O   UNK     0       7.398   0.596   0.000  0.00  0.00           O+0
HETATM   37  O   UNK     0       5.918   0.168   0.000  0.00  0.00           O+0
HETATM   38  O   UNK     0       3.329   0.809   0.000  0.00  0.00           O+0
HETATM   39  O   UNK     0       1.849  -5.171   0.000  0.00  0.00           O+0
HETATM   40  O   UNK     0       9.247   2.518   0.000  0.00  0.00           O+0
HETATM   41  O   UNK     0      11.837   1.877   0.000  0.00  0.00           O+0
HETATM   42  O   UNK     0      -2.959  -2.394   0.000  0.00  0.00           O+0
HETATM   43  H   UNK     0      18.495  -4.530   0.000  0.00  0.00           H+0
HETATM   44  H   UNK     0      18.125  -0.472   0.000  0.00  0.00           H+0
HETATM   45  H   UNK     0      15.906  -3.889   0.000  0.00  0.00           H+0
HETATM   46  H   UNK     0      15.536   0.168   0.000  0.00  0.00           H+0
CONECT    1    3                                                            
CONECT    2   42                                                            
CONECT    3    1    4   43                                                  
CONECT    4    3    5   44                                                  
CONECT    5    4    6   45                                                  
CONECT    6    5   14   46                                                  
CONECT    7    8   12                                                       
CONECT    8    7   15                                                       
CONECT    9   12   13                                                       
CONECT   10   13   14                                                       
CONECT   11   16   17                                                       
CONECT   12    7    9   18                                                  
CONECT   13    9   10   19                                                  
CONECT   14    6   10   32                                                  
CONECT   15    8   20   25                                                  
CONECT   16   11   21   33                                                  
CONECT   17   11   26   42                                                  
CONECT   18   12   20   27                                                  
CONECT   19   13   27   31                                                  
CONECT   20   15   18   28                                                  
CONECT   21   16   22   29                                                  
CONECT   22   21   26   30                                                  
CONECT   23   24   25   30                                                  
CONECT   24   23   28   29                                                  
CONECT   25   15   23   34                                                  
CONECT   26   17   22   35                                                  
CONECT   27   18   19   36                                                  
CONECT   28   20   24   37                                                  
CONECT   29   21   24   38                                                  
CONECT   30   22   23   39                                                  
CONECT   31   19   40   41                                                  
CONECT   32   14                                                            
CONECT   33   16                                                            
CONECT   34   25                                                            
CONECT   35   26                                                            
CONECT   36   27                                                            
CONECT   37   28                                                            
CONECT   38   29                                                            
CONECT   39   30                                                            
CONECT   40   31                                                            
CONECT   41   31                                                            
CONECT   42    2   17                                                       
CONECT   43    3                                                            
CONECT   44    4                                                            
CONECT   45    5                                                            
CONECT   46    6                                                            
MASTER        0    0    0    0    0    0    0    0   46    0  100    0
END

Synonyms

Not Available

Molecular Formula

C₃₁H₂₄O₁₁

Average Mass

572.522

Monoisotopic Mass

572.131861593

IUPAC Name

2,5,13,17,20-pentahydroxy-18-methoxy-15,22-dioxo-7-[(3E,5E)-2-oxohepta-3,5-dien-1-yl]pentacyclo[12.8.0.0^{3,12}.0^{4,9}.0^{16,21}]docosa-1,3(12),4,6,8,13,16(21),17,19-nonaene-6-carboxylic acid

Traditional Name

2,5,13,17,20-pentahydroxy-18-methoxy-15,22-dioxo-7-[(3E,5E)-2-oxohepta-3,5-dien-1-yl]pentacyclo[12.8.0.0^{3,12}.0^{4,9}.0^{16,21}]docosa-1,3(12),4,6,8,13,16(21),17,19-nonaene-6-carboxylic acid

CAS Registry Number

Not Available

SMILES

[H]\C(C)=C(\[H])/C(/[H])=C(\[H])C(=O)CC1=C(C(O)=O)C(O)=C2C(CCC3=C(O)C4=C(C(O)=C23)C(=O)C2=C(C(O)=C(OC)C=C2O)C4=O)=C1

InChI Identifier

InChI=1S/C31H24O11/c1-3-4-5-6-14(32)10-13-9-12-7-8-15-20(18(12)27(36)19(13)31(40)41)28(37)24-23(25(15)34)30(39)22-21(29(24)38)16(33)11-17(42-2)26(22)35/h3-6,9,11,33-37H,7-8,10H2,1-2H3,(H,40,41)/b4-3+,6-5+

InChI Key

LKUAAWSFMBXAPQ-VNKDHWASSA-N

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as tetracenequinones. These are polyaromatic hydrocarbon derivatives containing a tetracyclic cycle made up of four linearly fused benzene rings, one of which bears two ketone groups at position 1 and 4.

Kingdom

Super Class

Class

Sub Class

Direct Parent

Alternative Parents

Substituents

Tetracenequinone
9,10-anthraquinone
1,4-anthraquinone
Anthracene
Phenanthrene
2-naphthalenecarboxylic acid
2-naphthalenecarboxylic acid or derivatives
1-naphthol
Hydroxybenzoic acid
Salicylic acid or derivatives
Anisole
Aryl ketone
Phenol ether
Alkyl aryl ether
Phenol
1-hydroxy-4-unsubstituted benzenoid
1-hydroxy-2-unsubstituted benzenoid
Alpha,beta-unsaturated ketone
Vinylogous acid
Acryloyl-group
Enone
Ketone
Carboxylic acid
Carboxylic acid derivative
Polyol
Ether
Carbonyl group
Organic oxygen compound
Organic oxide
Hydrocarbon derivative
Organooxygen compound
Aromatic homopolycyclic compound

Molecular Framework

Aromatic homopolycyclic compounds

External Descriptors

Not Available

Functional Ontology

Not Available

Physical Properties

State

Expected Solid

Predicted Properties

Property	Value	Source
Water Solubility	0.042 g/L	ALOGPS
logP	3.95	ALOGPS
logP	8	ChemAxon
logS	-4.1	ALOGPS
pKa (Strongest Acidic)	2.67	ChemAxon
pKa (Strongest Basic)	-4.7	ChemAxon
Physiological Charge	-1	ChemAxon
Hydrogen Acceptor Count	11	ChemAxon
Hydrogen Donor Count	6	ChemAxon
Polar Surface Area	198.89 Å²	ChemAxon
Rotatable Bond Count	6	ChemAxon
Refractivity	153.69 m³·mol⁻¹	ChemAxon
Polarizability	58.38 Å³	ChemAxon
Number of Rings	5	ChemAxon
Bioavailability	No	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	Yes	ChemAxon

Spectra

Not Available

Biological Properties

Cellular Locations

Not Available

Biospecimen Locations

Not Available

Tissue Locations

Not Available

Associated OMIM IDs

114500 (Colorectal cancer)
610247 (Eosinophilic esophagitis)

Human Proteins and Enzymes

Protein ID	Protein Name	Protein Type	Uniprot ID	Species

Human Pathways

Pathways

Name	SMPDB/PathBank

Metabolic Reactions

Not Available

Health Effects and Bioactivity

Health Outcome/Bioactivity	Metabolite Response/Effect	Evidence Type	Host and Biospecimen	Data Source	Reference

Microbial Sources

Superkingdom/Kingdom	Phylum	Total species	Hosts and Body Sites	Microbial Links
Bacteria	Actinobacteria	1		Metabolic reconstruction

Exposure Sources

Source Type	Source Sub-type	Species	Data Source	Reference

Host Biospecimen and Location

Host and Biospecimen	Status	Mean	Std	Min	Max	Units	Age	Sex	Health Condition	Data Source	Reference

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FooDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

34984823

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

90479008

PDB ID

Not Available

ChEBI ID

Not Available

Food Biomarker Ontology

Not Available

References

Synthesis Reference

Not Available

General References

van Santen JA, Poynton EF, Iskakova D, McMann E, Alsup TA, Clark TN, Fergusson CH, Fewer DP, Hughes AH, McCadden CA, Parra J, Soldatou S, Rudolf JD, Janssen EM, Duncan KR, Linington RG: The Natural Products Atlas 2.0: a database of microbially-derived natural products. Nucleic Acids Res. 2022 Jan 7;50(D1):D1317-D1323. doi: 10.1093/nar/gkab941. [PubMed:34718710 ]

Showing metabocard for Fredericamycin C (MMDBc0012092)

MOL for #<Metabolite:0x00007fed080c2d38>

3D MOL for #<Metabolite:0x00007fed080c2d38>

3D SDF for #<Metabolite:0x00007fed080c2d38>

3D-SDF for #<Metabolite:0x00007fed080c2d38>

PDB for #<Metabolite:0x00007fed080c2d38>

3D PDB for #<Metabolite:0x00007fed080c2d38>

SMILES for #<Metabolite:0x00007fed080c2d38>

INCHI for #<Metabolite:0x00007fed080c2d38>

Structure for #<Metabolite:0x00007fed080c2d38>

3D Structure for #<Metabolite:0x00007fed080c2d38>