MiMeDB: Showing metabocard for Brevione H (MMDBc0012787)

Record Information

Version

1.0

Status

Detected and Quantified

Creation Date

2021-05-15 04:14:49 UTC

Update Date

2022-08-31 06:35:02 UTC

Metabolite ID

MMDBc0012787

Metabolite Identification

Common Name

Brevione H

Description

Brevione H belongs to the class of organic compounds known as pyranones and derivatives. Pyranones and derivatives are compounds containing a pyran ring which bears a ketone. Based on a literature review very few articles have been published on Brevione H.

Structure

MOL SDF PDB SMILES InChI


  Mrv1652305152106142D          

 40 46  0  0  1  0            999 V2000
    4.8756   -5.0696    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.4271   -2.3191    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5724   -1.6839    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0381   -2.4417    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3834   -3.3301    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3434   -4.7291    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5278   -4.6049    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.3587   -3.7587    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.8371   -2.0871    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7359   -2.4089    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7053   -4.2624    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1990   -2.6101    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6107   -2.5080    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3435   -2.8869    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.3724   -2.9338    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9042   -4.0656    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    2.6090   -2.3782    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    3.9287   -2.5792    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.0456   -3.7774    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0839   -2.9532    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7429   -3.1923    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.8176   -4.0684    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   -0.6872   -4.1563    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0666   -4.5394    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.5585   -3.3165    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    2.2276   -3.8365    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    1.3329   -3.4242    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    6.1215   -2.5882    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7255   -4.9804    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.6623   -5.1102    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3818   -3.7111    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.3419   -1.9993    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.2710   -4.7576    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.8795   -2.7350    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.1591   -4.8502    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.9710   -2.9012    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.1612   -1.7876    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.0432   -3.9607    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.3022   -4.7126    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.8640   -5.3391    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
  7  6  1  0  0  0  0
 11  1  1  0  0  0  0
 11  8  2  0  0  0  0
 12  2  1  0  0  0  0
 12  9  2  0  0  0  0
 13  3  1  0  0  0  0
 14  4  1  0  0  0  0
 14 13  2  0  0  0  0
 15  8  1  0  0  0  0
 15 10  1  0  0  0  0
 16  6  1  0  0  0  0
 16 11  1  0  0  0  0
 17  9  1  0  0  0  0
 18 10  1  0  0  0  0
 20 13  1  0  0  0  0
 20 19  2  0  0  0  0
 21 17  1  0  0  0  0
 22 19  1  0  0  0  0
 23 19  1  0  0  0  0
 25  5  1  6  0  0  0
 25 16  1  0  0  0  0
 25 18  1  0  0  0  0
 25 21  1  0  0  0  0
 26  7  1  1  0  0  0
 26 21  1  0  0  0  0
 26 24  1  0  0  0  0
 27 12  1  0  0  0  0
 27 22  1  0  0  0  0
 27 26  1  0  0  0  0
 28 15  2  0  0  0  0
 29 23  2  0  0  0  0
 24 30  1  1  0  0  0
 31 14  1  0  0  0  0
 31 23  1  0  0  0  0
 32 17  1  0  0  0  0
 32 18  1  0  0  0  0
 33 22  1  0  0  0  0
 33 24  1  0  0  0  0
 34 20  1  0  0  0  0
 27 34  1  1  0  0  0
 16 35  1  1  0  0  0
 17 36  1  6  0  0  0
 18 37  1  6  0  0  0
 21 38  1  1  0  0  0
 22 39  1  6  0  0  0
 24 40  1  6  0  0  0
M  END


  Mrv1652305152106142D          

 40 46  0  0  1  0            999 V2000
    4.8756   -5.0696    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.4271   -2.3191    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5724   -1.6839    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0381   -2.4417    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3834   -3.3301    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3434   -4.7291    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5278   -4.6049    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.3587   -3.7587    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.8371   -2.0871    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7359   -2.4089    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7053   -4.2624    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1990   -2.6101    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6107   -2.5080    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3435   -2.8869    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.3724   -2.9338    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9042   -4.0656    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    2.6090   -2.3782    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    3.9287   -2.5792    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.0456   -3.7774    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0839   -2.9532    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7429   -3.1923    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.8176   -4.0684    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   -0.6872   -4.1563    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0666   -4.5394    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.5585   -3.3165    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    2.2276   -3.8365    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    1.3329   -3.4242    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    6.1215   -2.5882    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7255   -4.9804    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.6623   -5.1102    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3818   -3.7111    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.3419   -1.9993    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.2710   -4.7576    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.8795   -2.7350    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.1591   -4.8502    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.9710   -2.9012    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.1612   -1.7876    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.0432   -3.9607    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.3022   -4.7126    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.8640   -5.3391    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
  7  6  1  0  0  0  0
 11  1  1  0  0  0  0
 11  8  2  0  0  0  0
 12  2  1  0  0  0  0
 12  9  2  0  0  0  0
 13  3  1  0  0  0  0
 14  4  1  0  0  0  0
 14 13  2  0  0  0  0
 15  8  1  0  0  0  0
 15 10  1  0  0  0  0
 16  6  1  0  0  0  0
 16 11  1  0  0  0  0
 17  9  1  0  0  0  0
 18 10  1  0  0  0  0
 20 13  1  0  0  0  0
 20 19  2  0  0  0  0
 21 17  1  0  0  0  0
 22 19  1  0  0  0  0
 23 19  1  0  0  0  0
 25  5  1  6  0  0  0
 25 16  1  0  0  0  0
 25 18  1  0  0  0  0
 25 21  1  0  0  0  0
 26  7  1  1  0  0  0
 26 21  1  0  0  0  0
 26 24  1  0  0  0  0
 27 12  1  0  0  0  0
 27 22  1  0  0  0  0
 27 26  1  0  0  0  0
 28 15  2  0  0  0  0
 29 23  2  0  0  0  0
 24 30  1  1  0  0  0
 31 14  1  0  0  0  0
 31 23  1  0  0  0  0
 32 17  1  0  0  0  0
 32 18  1  0  0  0  0
 33 22  1  0  0  0  0
 33 24  1  0  0  0  0
 34 20  1  0  0  0  0
 27 34  1  1  0  0  0
 16 35  1  1  0  0  0
 17 36  1  6  0  0  0
 18 37  1  6  0  0  0
 21 38  1  1  0  0  0
 22 39  1  6  0  0  0
 24 40  1  6  0  0  0
M  END
> <DATABASE_ID>
MMDBc0012787

> <DATABASE_NAME>
MIME

> <SMILES>
[H][C@]1(O)O[C@@]2([H])C3=C(O[C@]22C(C)=C[C@@]4([H])O[C@@]5([H])CC(=O)C=C(C)[C@]6([H])CC[C@@]12[C@@]4([H])[C@@]56C)C(C)=C(C)OC3=O

> <INCHI_IDENTIFIER>
InChI=1S/C27H30O7/c1-11-8-15(28)10-18-25(5)16(11)6-7-26-21(25)17(32-18)9-12(2)27(26)22(33-24(26)30)19-20(34-27)13(3)14(4)31-23(19)29/h8-9,16-18,21-22,24,30H,6-7,10H2,1-5H3/t16-,17+,18-,21+,22-,24-,25+,26+,27+/m0/s1

> <INCHI_KEY>
JPXZJDMFVHWBKF-JPHWDXFPSA-N

> <FORMULA>
C27H30O7

> <MOLECULAR_WEIGHT>
466.53

> <EXACT_MASS>
466.199153306

> <JCHEM_ACCEPTOR_COUNT>
6

> <JCHEM_ATOM_COUNT>
64

> <JCHEM_AVERAGE_POLARIZABILITY>
49.26114297289725

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
1

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
1

> <JCHEM_IUPAC>
(1R,4S,12S,14S,15S,18S,23S,24S,25R)-14-hydroxy-3,7,8,19,24-pentamethyl-5,9,13,26-tetraoxaheptacyclo[21.2.1.0^{4,12}.0^{4,15}.0^{6,11}.0^{15,25}.0^{18,24}]hexacosa-2,6(11),7,19-tetraene-10,21-dione

> <ALOGPS_LOGP>
2.55

> <JCHEM_LOGP>
2.3807658336666657

> <ALOGPS_LOGS>
-3.79

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
7

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA>
18.375483816541063

> <JCHEM_PKA_STRONGEST_ACIDIC>
11.82296916030845

> <JCHEM_PKA_STRONGEST_BASIC>
-3.87435041335887

> <JCHEM_POLAR_SURFACE_AREA>
91.29000000000002

> <JCHEM_REFRACTIVITY>
123.81379999999994

> <JCHEM_ROTATABLE_BOND_COUNT>
0

> <JCHEM_RULE_OF_FIVE>
1

> <ALOGPS_SOLUBILITY>
7.63e-02 g/l

> <JCHEM_TRADITIONAL_IUPAC>
(1R,4S,12S,14S,15S,18S,23S,24S,25R)-14-hydroxy-3,7,8,19,24-pentamethyl-5,9,13,26-tetraoxaheptacyclo[21.2.1.0^{4,12}.0^{4,15}.0^{6,11}.0^{15,25}.0^{18,24}]hexacosa-2,6(11),7,19-tetraene-10,21-dione

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 15-MAY-21   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   15-MAY-21         0                                  
HETATM    1  C   UNK     0       9.101  -9.463   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0       0.797  -4.329   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0      -1.068  -3.143   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0      -3.804  -4.558   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0       8.182  -6.216   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0       6.241  -8.828   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0       4.719  -8.596   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0      10.003  -7.016   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0       3.429  -3.896   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0       8.840  -4.497   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0       8.783  -7.956   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0       2.238  -4.872   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0      -1.140  -4.682   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0      -2.508  -5.389   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0      10.028  -5.476   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0       7.288  -7.589   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0       4.870  -4.439   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0       7.334  -4.814   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0       0.085  -7.051   0.000  0.00  0.00           C+0
HETATM   20  C   UNK     0       0.157  -5.513   0.000  0.00  0.00           C+0
HETATM   21  C   UNK     0       5.120  -5.959   0.000  0.00  0.00           C+0
HETATM   22  C   UNK     0       1.526  -7.594   0.000  0.00  0.00           C+0
HETATM   23  C   UNK     0      -1.283  -7.758   0.000  0.00  0.00           C+0
HETATM   24  C   UNK     0       3.858  -8.473   0.000  0.00  0.00           C+0
HETATM   25  C   UNK     0       6.643  -6.191   0.000  0.00  0.00           C+0
HETATM   26  C   UNK     0       4.158  -7.161   0.000  0.00  0.00           C+0
HETATM   27  C   UNK     0       2.488  -6.392   0.000  0.00  0.00           C+0
HETATM   28  O   UNK     0      11.427  -4.831   0.000  0.00  0.00           O+0
HETATM   29  O   UNK     0      -1.354  -9.297   0.000  0.00  0.00           O+0
HETATM   30  O   UNK     0       4.970  -9.539   0.000  0.00  0.00           O+0
HETATM   31  O   UNK     0      -2.579  -6.927   0.000  0.00  0.00           O+0
HETATM   32  O   UNK     0       6.238  -3.732   0.000  0.00  0.00           O+0
HETATM   33  O   UNK     0       2.373  -8.881   0.000  0.00  0.00           O+0
HETATM   34  O   UNK     0       1.642  -5.105   0.000  0.00  0.00           O+0
HETATM   35  H   UNK     0       7.764  -9.054   0.000  0.00  0.00           H+0
HETATM   36  H   UNK     0       3.679  -5.416   0.000  0.00  0.00           H+0
HETATM   37  H   UNK     0       7.768  -3.337   0.000  0.00  0.00           H+0
HETATM   38  H   UNK     0       5.681  -7.393   0.000  0.00  0.00           H+0
HETATM   39  H   UNK     0       0.564  -8.797   0.000  0.00  0.00           H+0
HETATM   40  H   UNK     0       3.479  -9.966   0.000  0.00  0.00           H+0
CONECT    1   11                                                            
CONECT    2   12                                                            
CONECT    3   13                                                            
CONECT    4   14                                                            
CONECT    5   25                                                            
CONECT    6    7   16                                                       
CONECT    7    6   26                                                       
CONECT    8   11   15                                                       
CONECT    9   12   17                                                       
CONECT   10   15   18                                                       
CONECT   11    1    8   16                                                  
CONECT   12    2    9   27                                                  
CONECT   13    3   14   20                                                  
CONECT   14    4   13   31                                                  
CONECT   15    8   10   28                                                  
CONECT   16    6   11   25   35                                             
CONECT   17    9   21   32   36                                             
CONECT   18   10   25   32   37                                             
CONECT   19   20   22   23                                                  
CONECT   20   13   19   34                                                  
CONECT   21   17   25   26   38                                             
CONECT   22   19   27   33   39                                             
CONECT   23   19   29   31                                                  
CONECT   24   26   30   33   40                                             
CONECT   25    5   16   18   21                                             
CONECT   26    7   21   24   27                                             
CONECT   27   12   22   26   34                                             
CONECT   28   15                                                            
CONECT   29   23                                                            
CONECT   30   24                                                            
CONECT   31   14   23                                                       
CONECT   32   17   18                                                       
CONECT   33   22   24                                                       
CONECT   34   20   27                                                       
CONECT   35   16                                                            
CONECT   36   17                                                            
CONECT   37   18                                                            
CONECT   38   21                                                            
CONECT   39   22                                                            
CONECT   40   24                                                            
MASTER        0    0    0    0    0    0    0    0   40    0   92    0
END

Synonyms

Not Available

Molecular Formula

C₂₇H₃₀O₇

Average Mass

466.53

Monoisotopic Mass

466.199153306

IUPAC Name

(1R,4S,12S,14S,15S,18S,23S,24S,25R)-14-hydroxy-3,7,8,19,24-pentamethyl-5,9,13,26-tetraoxaheptacyclo[21.2.1.0^{4,12}.0^{4,15}.0^{6,11}.0^{15,25}.0^{18,24}]hexacosa-2,6(11),7,19-tetraene-10,21-dione

Traditional Name

(1R,4S,12S,14S,15S,18S,23S,24S,25R)-14-hydroxy-3,7,8,19,24-pentamethyl-5,9,13,26-tetraoxaheptacyclo[21.2.1.0^{4,12}.0^{4,15}.0^{6,11}.0^{15,25}.0^{18,24}]hexacosa-2,6(11),7,19-tetraene-10,21-dione

CAS Registry Number

Not Available

SMILES

[H][C@]1(O)O[C@@]2([H])C3=C(O[C@]22C(C)=C[C@@]4([H])O[C@@]5([H])CC(=O)C=C(C)[C@]6([H])CC[C@@]12[C@@]4([H])[C@@]56C)C(C)=C(C)OC3=O

InChI Identifier

InChI=1S/C27H30O7/c1-11-8-15(28)10-18-25(5)16(11)6-7-26-21(25)17(32-18)9-12(2)27(26)22(33-24(26)30)19-20(34-27)13(3)14(4)31-23(19)29/h8-9,16-18,21-22,24,30H,6-7,10H2,1-5H3/t16-,17+,18-,21+,22-,24-,25+,26+,27+/m0/s1

InChI Key

JPXZJDMFVHWBKF-JPHWDXFPSA-N

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as pyranones and derivatives. Pyranones and derivatives are compounds containing a pyran ring which bears a ketone.

Kingdom

Organic compounds

Super Class

Organoheterocyclic compounds

Class

Pyrans

Sub Class

Pyranones and derivatives

Direct Parent

Pyranones and derivatives

Alternative Parents

Substituents

Alkyl aryl ether
Pyranone
Monosaccharide
Heteroaromatic compound
Vinylogous ester
Oxolane
Hemiacetal
Ketone
Lactone
Cyclic ketone
Dialkyl ether
Ether
Oxacycle
Organic oxide
Organic oxygen compound
Hydrocarbon derivative
Carbonyl group
Organooxygen compound
Aromatic heteropolycyclic compound

Molecular Framework

Aromatic heteropolycyclic compounds

External Descriptors

Not Available

Functional Ontology

Not Available

Physical Properties

State

Expected Solid

Predicted Properties

Property	Value	Source
Water Solubility	0.076 g/L	ALOGPS
logP	2.55	ALOGPS
logP	2.38	ChemAxon
logS	-3.8	ALOGPS
pKa (Strongest Acidic)	11.82	ChemAxon
pKa (Strongest Basic)	-3.9	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	6	ChemAxon
Hydrogen Donor Count	1	ChemAxon
Polar Surface Area	91.29 Å²	ChemAxon
Rotatable Bond Count	0	ChemAxon
Refractivity	123.81 m³·mol⁻¹	ChemAxon
Polarizability	49.26 Å³	ChemAxon
Number of Rings	7	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	Yes	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

Spectra

Not Available

Biological Properties

Cellular Locations

Not Available

Biospecimen Locations

Not Available

Tissue Locations

Not Available

Associated OMIM IDs

114500 (Colorectal cancer)
610247 (Eosinophilic esophagitis)

Human Proteins and Enzymes

Protein ID	Protein Name	Protein Type	Uniprot ID	Species

Human Pathways

Pathways

Name	SMPDB/PathBank

Metabolic Reactions

Not Available

Health Effects and Bioactivity

Health Outcome/Bioactivity	Metabolite Response/Effect	Evidence Type	Host and Biospecimen	Data Source	Reference

Microbial Sources

Superkingdom/Kingdom	Phylum	Total species	Hosts and Body Sites	Microbial Links
Eukaryota/Fungi	Ascomycota	1	Human feces	Metabolic reconstruction

Exposure Sources

Source Type	Source Sub-type	Species	Data Source	Reference

Host Biospecimen and Location

Host and Biospecimen	Status	Mean	Std	Min	Max	Units	Age	Sex	Health Condition	Data Source	Reference

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FooDB ID

Not Available

KNApSAcK ID

C00047767

Chemspider ID

24629094

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

44139746

PDB ID

Not Available

ChEBI ID

Not Available

Food Biomarker Ontology

Not Available

References

Synthesis Reference

Not Available

General References

van Santen JA, Poynton EF, Iskakova D, McMann E, Alsup TA, Clark TN, Fergusson CH, Fewer DP, Hughes AH, McCadden CA, Parra J, Soldatou S, Rudolf JD, Janssen EM, Duncan KR, Linington RG: The Natural Products Atlas 2.0: a database of microbially-derived natural products. Nucleic Acids Res. 2022 Jan 7;50(D1):D1317-D1323. doi: 10.1093/nar/gkab941. [PubMed:34718710 ]

Showing metabocard for Brevione H (MMDBc0012787)

MOL for #<Metabolite:0x00007fecfc8e2d80>

3D MOL for #<Metabolite:0x00007fecfc8e2d80>

3D SDF for #<Metabolite:0x00007fecfc8e2d80>

3D-SDF for #<Metabolite:0x00007fecfc8e2d80>

PDB for #<Metabolite:0x00007fecfc8e2d80>

3D PDB for #<Metabolite:0x00007fecfc8e2d80>

SMILES for #<Metabolite:0x00007fecfc8e2d80>

INCHI for #<Metabolite:0x00007fecfc8e2d80>

Structure for #<Metabolite:0x00007fecfc8e2d80>

3D Structure for #<Metabolite:0x00007fecfc8e2d80>