Mrv1652305152110382D
25 27 0 0 1 0 999 V2000
5.0238 0.4866 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
4.0132 0.1646 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
1.7525 0.2234 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
3.3246 0.7244 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
3.5950 -0.4882 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
3.5751 3.2859 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
4.8821 1.5377 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
1.6781 1.8155 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
3.8256 2.4999 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
2.7691 3.4620 0.0000 C 0 0 1 0 0 0 0 0 0 0 0 0
4.6316 2.3238 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
2.2880 1.2600 0.0000 C 0 0 1 0 0 0 0 0 0 0 0 0
2.2136 2.8520 0.0000 C 0 0 1 0 0 0 0 0 0 0 0 0
3.2701 1.8899 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
4.3266 0.9278 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
2.5385 0.4739 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
2.4641 2.0660 0.0000 C 0 0 1 0 0 0 0 0 0 0 0 0
2.5186 4.2480 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
5.1871 2.9337 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
1.4076 3.0281 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
2.7890 -0.3121 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
3.5206 1.1038 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
1.9631 3.6381 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0
3.1121 1.2985 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0
1.6581 2.2421 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0
9 6 1 0 0 0 0
10 6 1 0 0 0 0
11 7 1 0 0 0 0
11 9 1 0 0 0 0
12 8 1 0 0 0 0
13 10 1 0 0 0 0
14 9 2 0 0 0 0
15 1 1 0 0 0 0
15 2 1 0 0 0 0
15 7 1 0 0 0 0
16 3 1 0 0 0 0
16 4 1 0 0 0 0
12 16 1 6 0 0 0
17 8 1 1 0 0 0
17 12 1 0 0 0 0
17 13 1 0 0 0 0
17 14 1 0 0 0 0
10 18 1 1 0 0 0
19 11 2 0 0 0 0
13 20 1 1 0 0 0
21 5 1 0 0 0 0
21 16 1 0 0 0 0
22 14 1 0 0 0 0
22 15 1 0 0 0 0
10 23 1 6 0 0 0
12 24 1 1 0 0 0
13 25 1 6 0 0 0
M END
> <DATABASE_ID>
MMDBc0018451
> <DATABASE_NAME>
MIME
> <SMILES>
[H][C@]1(C[C@@]11C2=C(C[C@]([H])(O)[C@]1([H])O)C(=O)CC(C)(C)O2)C(C)(C)OC
> <INCHI_IDENTIFIER>
InChI=1S/C17H26O5/c1-15(2)7-11(19)9-6-10(18)13(20)17(14(9)22-15)8-12(17)16(3,4)21-5/h10,12-13,18,20H,6-8H2,1-5H3/t10-,12-,13-,17+/m0/s1
> <INCHI_KEY>
PTEAJHVZALZNSN-HTWFXAOOSA-N
> <FORMULA>
C17H26O5
> <MOLECULAR_WEIGHT>
310.39
> <EXACT_MASS>
310.178023937
> <JCHEM_ACCEPTOR_COUNT>
5
> <JCHEM_ATOM_COUNT>
48
> <JCHEM_AVERAGE_POLARIZABILITY>
33.3072692287287
> <JCHEM_BIOAVAILABILITY>
1
> <JCHEM_DONOR_COUNT>
2
> <JCHEM_FORMAL_CHARGE>
0
> <JCHEM_GHOSE_FILTER>
1
> <JCHEM_IUPAC>
(3'R,6S,7R,8R)-6,7-dihydroxy-3'-(2-methoxypropan-2-yl)-2,2-dimethyl-2,3,4,5,6,7-hexahydrospiro[1-benzopyran-8,1'-cyclopropane]-4-one
> <ALOGPS_LOGP>
1.16
> <JCHEM_LOGP>
0.23384171499999906
> <ALOGPS_LOGS>
-2.01
> <JCHEM_MDDR_LIKE_RULE>
0
> <JCHEM_NUMBER_OF_RINGS>
3
> <JCHEM_PHYSIOLOGICAL_CHARGE>
0
> <JCHEM_PKA>
15.043021857536974
> <JCHEM_PKA_STRONGEST_ACIDIC>
13.47709484940263
> <JCHEM_PKA_STRONGEST_BASIC>
-3.1984415306331107
> <JCHEM_POLAR_SURFACE_AREA>
75.99000000000001
> <JCHEM_REFRACTIVITY>
82.4207
> <JCHEM_ROTATABLE_BOND_COUNT>
2
> <JCHEM_RULE_OF_FIVE>
1
> <ALOGPS_SOLUBILITY>
3.03e+00 g/l
> <JCHEM_TRADITIONAL_IUPAC>
(3'R,6S,7R,8R)-6,7-dihydroxy-3'-(2-methoxypropan-2-yl)-2,2-dimethyl-3,5,6,7-tetrahydrospiro[1-benzopyran-8,1'-cyclopropane]-4-one
> <JCHEM_VEBER_RULE>
0
$$$$