Record Information
Version1.0
StatusDetected and Quantified
Creation Date2021-11-17 23:52:36 UTC
Update Date2024-10-13 07:16:25 UTC
Metabolite IDMMDBc0030065
Metabolite Identification
Common NameGlutathionylspermidine
DescriptionGlutathionylspermidine is a member of the chemical class known as Alpha Amino Acids and Derivatives. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon). Glutathionylspermidine (Gsp) is a metabolite common to Escherichia coli and protozoal parasites of the Trypanosoma family. (PMID 9398217 ) Glutathionylspermidine is an intermediate formed in the biosynthesis of trypanothione, an essential metabolite in defence against chemical and oxidative stress in the Kinetoplastida. (PMID 18959765 ) Glutathionylspermidine is formed as end product and the enzyme lacks TryS activity. (PMID 12049631 )
Structure
Synonyms
ValueSource
N1-(gamma-L-Glutamyl-L-cysteinyl-glycyl)-spermidineChEBI
N1-(g-L-Glutamyl-L-cysteinyl-glycyl)-spermidineGenerator
N1-(Γ-L-glutamyl-L-cysteinyl-glycyl)-spermidineGenerator
N'-glutathionylspermidine disulfideMeSH
Molecular FormulaC17H34N6O5S
Average Mass434.554
Monoisotopic Mass434.231138918
IUPAC NameNot Available
Traditional NameNot Available
CAS Registry Number33932-35-3
SMILESNot Available
InChI Identifier
InChI=1S/C17H34N6O5S/c18-6-1-2-7-20-8-3-9-21-15(25)10-22-16(26)13(11-29)23-14(24)5-4-12(19)17(27)28/h12-13,20,29H,1-11,18-19H2,(H,21,25)(H,22,26)(H,23,24)(H,27,28)/t12-,13-/m0/s1
InChI KeyNEDQLXHBVHSKNV-STQMWFEESA-N