Record Information
Version1.0
StatusDetected and Quantified
Creation Date2021-11-18 00:37:38 UTC
Update Date2024-10-15 19:49:40 UTC
Metabolite IDMMDBc0031156
Metabolite Identification
Common NameN-Acetyl-alpha-neuraminate
DescriptionN-Acetyl-alpha-neuraminate is a sialic acid. Sialic acids are an important family of related 9-carbon sugars acids, present on the surface of many different cells and functioning in a wide range of different biological processes. They can be utilized by pathogens to evade the host immune response. N-acetylneuraminic acid is the most common sialic acid. A number of bacteria that can colonize humans (such as E. coli) make use of N-acetylneuraminic acid as a nutrient source. Production of the enzymes involved in N-acetylneuraminate degradation is induced by growth on sialic acid as the sole source of carbon, which is due to transcriptional regulation by the repressor NanR.↵
Structure
Synonyms
ValueSource
alpha-Neu5acChEBI
O-SIALIC ACIDChEBI
WURCS=2.0/1,1,0/[aad21122h-2a_2-6_5*ncc/3=o]/1/ChEBI
a-Neu5acGenerator
Α-neu5acGenerator
O-SIALateGenerator
N-Acetyl-a-neuraminateGenerator
5-(Acetylamino)-3,5-dideoxy-D-glycero-a-D-galacto-2-nonulopyranosonateHMDB
5-(Acetylamino)-3,5-dideoxy-D-glycero-a-D-galacto-2-nonulopyranosonic acidHMDB
5-(Acetylamino)-3,5-dideoxy-delta-glycero-alpha-delta-galacto-2-nonulopyranosonateHMDB
5-(Acetylamino)-3,5-dideoxy-delta-glycero-alpha-delta-galacto-2-nonulopyranosonic acidHMDB
5-Acetamido-3,5-dideoxy-a-D-glycero-D-galacto-nonulopyranosonateHMDB
5-Acetamido-3,5-dideoxy-a-D-glycero-D-galacto-nonulopyranosonic acidHMDB
5-Acetamido-3,5-dideoxy-alpha-delta-glycero-delta-galacto-nonulopyranosonateHMDB
5-Acetamido-3,5-dideoxy-alpha-delta-glycero-delta-galacto-nonulopyranosonic acidHMDB
N-Acetyl-a-D-neuraminateHMDB
N-Acetyl-a-D-neuraminic acidHMDB
N-Acetyl-alpha-delta-neuraminateHMDB
N-Acetyl-alpha-delta-neuraminic acidHMDB
N-Acetyl-alpha-neuraminateHMDB
PolySiaHMDB
Polysialic acidHMDB
N-Acetyl-alpha-neuraminic acidHMDB
N-Acetyl-α-neuraminateHMDB
N-Acetyl-α-neuraminic acidHMDB
Acid, N-acetylneuraminicHMDB
Acid, sialicHMDB
N Acetylneuraminic acidHMDB
N-Acetylneuraminic acidHMDB
Sialic acidHMDB
N-Acetyl-a-neuraminic acidGenerator
Molecular FormulaC11H19NO9
Average Mass309.2699
Monoisotopic Mass309.105981211
IUPAC NameNot Available
Traditional NameNot Available
CAS Registry Number21646-00-4
SMILESNot Available
InChI Identifier
InChI=1S/C11H19NO9/c1-4(14)12-7-5(15)2-11(20,10(18)19)21-9(7)8(17)6(16)3-13/h5-9,13,15-17,20H,2-3H2,1H3,(H,12,14)(H,18,19)/t5-,6+,7+,8+,9+,11+/m0/s1
InChI KeySQVRNKJHWKZAKO-YRMXFSIDSA-N