Record Information
Version1.0
StatusDetected and Quantified
Creation Date2021-11-18 00:37:51 UTC
Update Date2022-08-31 17:59:01 UTC
Metabolite IDMMDBc0031162
Metabolite Identification
Common Namemolybdenum cofactor
DescriptionMolybdenum cofactor is a cofactor required for the activity of enzymes such as sulfite oxidase, xanthine oxidoreductase, and aldehyde oxidase. It is a coordination complex formed between molybdopterin (which, despite the name, does not contain molybdenum) and an oxide of molybdenum. Molybdenum-containing enzymes catalyze basic metabolic reactions in the nitrogen, sulfur, and carbon cycles. With the exception of the nitrogenase cofactor, molybdenum is incorporated into proteins as the molybdenum cofactor that contains a mononuclear molybdenum atom coordinated to the sulfur atoms of a pterin derivative named molybdopterin. Certain microorganisms can also utilize tungsten in a similar fashion. Molybdenum-cofactor-containing enzymes catalyze the transfer of an oxygen atom, ultimately derived from or incorporated into water, to or from a substrate in a two-electron redox reaction.
Structure
SynonymsNot Available
Molecular FormulaC10H18MoN5O8PS2
Average Mass527.32
Monoisotopic Mass528.938848315
IUPAC Namemolybdenum(2+) ion ({4-hydroxy-2-imino-6,7-disulfanyl-1H,2H,5H,5aH,8H,9aH,10H-pyrano[3,2-g]pteridin-8-yl}methoxy)phosphonic acid dihydrate
Traditional Namemolybdenum(2+) ion molybdopterin cofactor dihydrate
CAS Registry Number73508-07-3
SMILES
O.O.[Mo++].OC1=NC(=N)NC2=C1NC1C(N2)OC(COP(O)(O)=O)C(S)=C1S
InChI Identifier
InChI=1S/C10H14N5O6PS2.Mo.2H2O/c11-10-14-7-4(8(16)15-10)12-3-6(24)5(23)2(21-9(3)13-7)1-20-22(17,18)19;;;/h2-3,9,12,23-24H,1H2,(H2,17,18,19)(H4,11,13,14,15,16);;2*1H2/q;+2;;
InChI KeyVUKICSJFFDCESC-UHFFFAOYSA-N