Showing metabocard for β-D-glucose 6-phosphate (MMDBc0032129)
Record Information | |||||
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Version | 1.0 | ||||
Status | Detected and Quantified | ||||
Creation Date | 2021-11-18 02:03:36 UTC | ||||
Update Date | 2022-08-31 18:30:45 UTC | ||||
Metabolite ID | MMDBc0032129 | ||||
Metabolite Identification | |||||
Common Name | β-D-glucose 6-phosphate | ||||
Description | beta-D-Glucose 6 phosphate (b-G6P) is the beta-anomer of glucose-6-phosphate. There are two anomers of glucose 6 phosphate, the alpha anomer and the beta anomer. Specifically, beta-D-Glucose 6-phosphate is glucose sugar phosphorylated on carbon 6. It is a very common metabolite in cells as the vast majority of glucose entering a cell will become phosphorylated in this way. The primary reason for the immediate phosphorylation of glucose is to prevent diffusion out of the cell. The phosphorylation adds a charged phosphate group so the glucose 6-phosphate cannot easily cross the cell membrane. b-G6P is involved in the glycolysis, gluconeogenesis, pentose phosphate, and glycogen and sucrose metabolic pathways [Kegg ID: C01172]. Beta-D-Glucose 6 phosphate can be generated through beta-D-fructose phosphate or alpha-D-glucose 6 phosphate (via glucose-6-phosphate isomerase) or beta-D glucose (via hexokinase). It can then be sent off to the pentose phosphate pathway which generates the useful cofactor NADPH as well as ribulose 5-phosphate, a carbon source for the synthesis of other molecules. Alternately if the cell needs energy or carbon skeletons for synthesis then glucose 6-phosphate is targeted for glycolysis. A third route is to have glucose 6 phosphate stored or converted to glycogen. | ||||
Structure | |||||
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Molecular Formula | C7H13O8P | ||||
Average Mass | 256.148 | ||||
Monoisotopic Mass | 256.035901536 | ||||
IUPAC Name | methylidene[(3,4,5,6-tetrahydroxyoxan-2-yl)methoxy]phosphonite | ||||
Traditional Name | methylidene(3,4,5,6-tetrahydroxyoxan-2-yl)methoxyphosphonite | ||||
CAS Registry Number | Not Available | ||||
SMILES | OC1OC(COP([O-])([O-])=C)C(O)C(O)C1O | ||||
InChI Identifier | InChI=1S/C7H13O8P/c1-16(12,13)14-2-3-4(8)5(9)6(10)7(11)15-3/h3-11H,1-2H2/q-2 | ||||
InChI Key | LCUFYJQRCBMIBL-UHFFFAOYSA-N | ||||
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