MiMeDB: Showing metabocard for (N(omega)-L-arginino)succinic acid (MMDBc0033045)

Record Information

Version

1.0

Status

Detected and Quantified

Creation Date

2021-11-19 04:32:22 UTC

Update Date

2024-04-20 06:09:17 UTC

Metabolite ID

MMDBc0033045

Metabolite Identification

Common Name

(N(omega)-L-arginino)succinic acid

Description

Structure

MOL SDF PDB SMILES InChI


  Mrv0541 02241222272D          

 20 19  0  0  1  0            999 V2000
    7.0206   -1.5339    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.3025   -1.9463    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    7.7318   -1.9463    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.0206   -0.7093    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.5878   -1.5339    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.4464   -1.5339    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.3025   -0.2935    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    7.7318   -0.2935    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.8697   -1.9463    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    5.5878   -0.7093    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    9.1644   -1.9463    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    8.4464   -0.7093    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.1551   -1.5339    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.4404   -1.9463    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7224   -1.5339    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0112   -1.9463    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    1.2966   -1.5339    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0112   -2.7708    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    0.5786   -1.9463    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.2966   -0.7093    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  1  3  1  0  0  0  0
  1  4  1  0  0  0  0
  2  5  1  0  0  0  0
  3  6  1  0  0  0  0
  4  7  1  0  0  0  0
  4  8  2  0  0  0  0
  5  9  1  0  0  0  0
  5 10  2  0  0  0  0
  6 11  1  0  0  0  0
  6 12  2  0  0  0  0
  9 13  1  0  0  0  0
 13 14  1  0  0  0  0
 14 15  1  0  0  0  0
 15 16  1  0  0  0  0
 16 17  1  0  0  0  0
 16 18  1  6  0  0  0
 17 19  1  0  0  0  0
 17 20  2  0  0  0  0
M  END
> <DATABASE_ID>
MMDBc0033045

> <DATABASE_NAME>
MIME

> <SMILES>
N[C@@H](CCCNC(=N)NC(CC(O)=O)C(O)=O)C(O)=O

> <INCHI_IDENTIFIER>
InChI=1S/C10H18N4O6/c11-5(8(17)18)2-1-3-13-10(12)14-6(9(19)20)4-7(15)16/h5-6H,1-4,11H2,(H,15,16)(H,17,18)(H,19,20)(H3,12,13,14)/t5-,6?/m0/s1

> <INCHI_KEY>
KDZOASGQNOPSCU-ZBHICJROSA-N

> <FORMULA>
C10H18N4O6

> <MOLECULAR_WEIGHT>
290.2731

> <EXACT_MASS>
290.122634328

> <JCHEM_ACCEPTOR_COUNT>
10

> <JCHEM_AVERAGE_POLARIZABILITY>
27.520676810856518

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
7

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
2-{3-[(4S)-4-amino-4-carboxybutyl]carbamimidamido}butanedioic acid

> <ALOGPS_LOGP>
-3.25

> <JCHEM_LOGP>
-5.797998694414509

> <ALOGPS_LOGS>
-2.80

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
0

> <JCHEM_PHYSIOLOGICAL_CHARGE>
-1

> <JCHEM_PKA>
3.234818865861278

> <JCHEM_PKA_STRONGEST_ACIDIC>
2.1364394242772287

> <JCHEM_PKA_STRONGEST_BASIC>
12.386778740975123

> <JCHEM_POLAR_SURFACE_AREA>
185.83

> <JCHEM_REFRACTIVITY>
75.3116

> <JCHEM_ROTATABLE_BOND_COUNT>
9

> <JCHEM_RULE_OF_FIVE>
0

> <ALOGPS_SOLUBILITY>
4.56e-01 g/l

> <JCHEM_TRADITIONAL_IUPAC>
arginosuccinate

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 24-FEB-12   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   24-FEB-12         0                                  
HETATM    1  C   UNK     0      13.105  -2.863   0.000  0.00  0.00           C+0
HETATM    2  N   UNK     0      11.765  -3.633   0.000  0.00  0.00           N+0
HETATM    3  C   UNK     0      14.433  -3.633   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0      13.105  -1.324   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0      10.431  -2.863   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0      15.767  -2.863   0.000  0.00  0.00           C+0
HETATM    7  O   UNK     0      11.765  -0.548   0.000  0.00  0.00           O+0
HETATM    8  O   UNK     0      14.433  -0.548   0.000  0.00  0.00           O+0
HETATM    9  N   UNK     0       9.090  -3.633   0.000  0.00  0.00           N+0
HETATM   10  N   UNK     0      10.431  -1.324   0.000  0.00  0.00           N+0
HETATM   11  O   UNK     0      17.107  -3.633   0.000  0.00  0.00           O+0
HETATM   12  O   UNK     0      15.767  -1.324   0.000  0.00  0.00           O+0
HETATM   13  C   UNK     0       7.756  -2.863   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0       6.422  -3.633   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0       5.082  -2.863   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0       3.754  -3.633   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0       2.420  -2.863   0.000  0.00  0.00           C+0
HETATM   18  N   UNK     0       3.754  -5.172   0.000  0.00  0.00           N+0
HETATM   19  O   UNK     0       1.080  -3.633   0.000  0.00  0.00           O+0
HETATM   20  O   UNK     0       2.420  -1.324   0.000  0.00  0.00           O+0
CONECT    1    2    3    4                                                  
CONECT    2    1    5                                                       
CONECT    3    1    6                                                       
CONECT    4    1    7    8                                                  
CONECT    5    2    9   10                                                  
CONECT    6    3   11   12                                                  
CONECT    7    4                                                            
CONECT    8    4                                                            
CONECT    9    5   13                                                       
CONECT   10    5                                                            
CONECT   11    6                                                            
CONECT   12    6                                                            
CONECT   13    9   14                                                       
CONECT   14   13   15                                                       
CONECT   15   14   16                                                       
CONECT   16   15   17   18                                                  
CONECT   17   16   19   20                                                  
CONECT   18   16                                                            
CONECT   19   17                                                            
CONECT   20   17                                                            
MASTER        0    0    0    0    0    0    0    0   20    0   38    0
END

Synonyms

Value	Source
2-(Nomega-L-arginino)succinate	ChEBI
L-Argininosuccinate	ChEBI
L-Argininosuccinic acid	ChEBI
L-Arginosuccinic acid	ChEBI
N(Omega)-(L-arginino)succinate	ChEBI
N-(L-Arginino) succinate	ChEBI
N-(L-Arginino)succinate	ChEBI
2-(Nomega-L-arginino)succinic acid	Generator
L-Arginosuccinate	Generator
N(Omega)-(L-arginino)succinic acid	Generator
N-(L-Arginino) succinic acid	Generator
N-(L-Arginino)succinic acid	Generator
(N(Omega)-L-arginino)succinate	Generator
2-(N(Omega)-L-arginino)succinic acid	ChEBI
Arginosuccinic acid	Generator
2-(N(Omega)-L-arginino)succinate	Generator

Molecular Formula

C₁₀H₁₈N₄O₆

Average Mass

290.2731

Monoisotopic Mass

290.122634328

IUPAC Name

2-{3-[(4S)-4-amino-4-carboxybutyl]carbamimidamido}butanedioic acid

Traditional Name

arginosuccinate

CAS Registry Number

2387-71-5

SMILES

N[C@@H](CCCNC(=N)NC(CC(O)=O)C(O)=O)C(O)=O

InChI Identifier

InChI=1S/C10H18N4O6/c11-5(8(17)18)2-1-3-13-10(12)14-6(9(19)20)4-7(15)16/h5-6H,1-4,11H2,(H,15,16)(H,17,18)(H,19,20)(H3,12,13,14)/t5-,6?/m0/s1

InChI Key

KDZOASGQNOPSCU-ZBHICJROSA-N

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as aspartic acid and derivatives. Aspartic acid and derivatives are compounds containing an aspartic acid or a derivative thereof resulting from reaction of aspartic acid at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom.

Kingdom

Organic compounds

Super Class

Organic acids and derivatives

Class

Carboxylic acids and derivatives

Sub Class

Amino acids, peptides, and analogues

Direct Parent

Aspartic acid and derivatives

Alternative Parents

Substituents

Aspartic acid or derivatives
Alpha-amino acid
L-alpha-amino acid
Tricarboxylic acid or derivatives
Guanidine
Amino acid
Organic 1,3-dipolar compound
Propargyl-type 1,3-dipolar organic compound
Carboximidamide
Carboxylic acid
Hydrocarbon derivative
Organopnictogen compound
Organic oxygen compound
Primary amine
Organooxygen compound
Organonitrogen compound
Primary aliphatic amine
Carbonyl group
Amine
Organic nitrogen compound
Organic oxide
Aliphatic acyclic compound

Molecular Framework

Aliphatic acyclic compounds

External Descriptors

guanidines (CHEBI:15682 )
non-proteinogenic L-alpha-amino acid (CHEBI:15682 )
L-arginine derivative (CHEBI:15682 )

Functional Ontology

Not Available

Physical Properties

State

Solid

Predicted Properties

Property	Value	Source
Water Solubility	0.46 g/L	ALOGPS
logP	-3.2	ALOGPS
logP	-5.8	ChemAxon
logS	-2.8	ALOGPS
pKa (Strongest Acidic)	2.14	ChemAxon
pKa (Strongest Basic)	12.39	ChemAxon
Physiological Charge	-1	ChemAxon
Hydrogen Acceptor Count	10	ChemAxon
Hydrogen Donor Count	7	ChemAxon
Polar Surface Area	185.83 Å²	ChemAxon
Rotatable Bond Count	9	ChemAxon
Refractivity	75.31 m³·mol⁻¹	ChemAxon
Polarizability	27.52 Å³	ChemAxon
Number of Rings	0	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

Spectra

Spectrum Type	Description	Splash Key	Deposition Date	View
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive	splash10-0007-7790000000-40bab13512c678a1bb92	2016-09-22	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 10V, Positive	splash10-0095-0290000000-ac08029bb2345ad10c07	2016-09-12	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 20V, Positive	splash10-004j-2980000000-3d79a8a83a98542f1490	2016-09-12	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 40V, Positive	splash10-00b9-4900000000-4a29cbcb04d32f3fd5be	2016-09-12	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 10V, Negative	splash10-000j-0490000000-78e51d9cfd4f53a300c7	2016-09-12	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 20V, Negative	splash10-0089-1930000000-2476b45b736db7be9592	2016-09-12	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 40V, Negative	splash10-05al-9700000000-a224ba3ad58c86883a36	2016-09-12	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 100 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 1000 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 200 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 300 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 400 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 500 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 600 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 700 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 800 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 900 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)		2022-08-20	View Spectrum

Biological Properties

Cellular Locations

Cytoplasm

Biospecimen Locations

Blood
Kidney
Placenta
Prostate
Urine

Tissue Locations

Not Available

Associated OMIM IDs

114500 (Colorectal cancer)
610247 (Eosinophilic esophagitis)

Human Proteins and Enzymes

Protein ID	Protein Name	Protein Type	Uniprot ID	Species

Human Pathways

Pathways

Name	SMPDB/PathBank

Metabolic Reactions

Not Available

Health Effects and Bioactivity

Health Outcome/Bioactivity	Metabolite Response/Effect	Evidence Type	Host and Biospecimen	Data Source	Reference
Argininosuccinic aciduria	Increased	Association	Human Urine	HMDB	12408190
Argininosuccinic aciduria	Increased	Association	Human Blood	HMDB	12408190
Argininosuccinic aciduria	Increased	Association	Human Urine	HMDB	5075233
Argininemia		Association	Human Urine	HMDB	MetaGene: Metabolic & Genetic Information Center (MIC: http://www.metagene.de)

Microbial Sources

Superkingdom/Kingdom	Phylum	Total species	Hosts and Body Sites	Microbial Links
Eukaryota/Fungi	Ascomycota	1	Human feces; Human saliva	Unknown

Exposure Sources

Source Type	Source Sub-type	Species	Data Source	Reference

Host Biospecimen and Location

Host and Biospecimen	Status	Mean	Min	Max	Units	Age	Sex	Health Condition	Data Source	Reference
Human Urine	Detected and Quantified	667			umol/mmol creatinine	Infant (0-1 year old)	Male	Argininosuccinic aciduria (ASL)	HMDB	12408190
Human Blood	Detected and Quantified	1515			uM	Infant (0-1 year old)	Male	Argininosuccinic aciduria (ASL)	HMDB	12408190
Human Urine	Detected and Quantified	1542			umol/mmol creatinine	Adult (>18 years old)	Both	Argininosuccinic aciduria (ASL)	HMDB	5075233
Human Blood	Detected and Quantified	300.0	270.0	458.0	uM	Children (1-13 years old)	Female	Argininosuccinyl-CoA lyase deficiency	HMDB	8582405
Human Urine	Detected and Quantified	0			umol/mmol creatinine	Adult (>18 years old)	Both	Normal	HMDB	21312326
Human Blood	Detected and Quantified	<2			uM	Infant (0-1 year old)	Male	Normal	HMDB	12408190
Human Urine	Detected and Quantified	<4			umol/mmol creatinine	Infant (0-1 year old)	Male	Normal	HMDB	12408190
Human Urine	Detected and Quantified		0	99	umol/mmol creatinine	Newborn (0-30 days old)	Both	Normal	HMDB	31506554
Human Urine	Detected and Quantified	0.65	0.0	1.3	umol/mmol creatinine	Children (1-13 years old)	Both	Argininemia	HMDB	MetaGene: Metabolic & Genetic Information Center (MIC: http://www.metagene.de)
Human Blood	Detected and Quantified		0	1	uM	Children (1 - 13 years old)	Both	Normal	HMDB	Argininosuccinate Lyase Deficiency. 2011 Feb 3 [Updated 2012 Feb 2]. In: Adam MP, Ardinger HH, Pagon RA, et al., editors. Available from: https://www.ncbi.nlm.nih.gov/books/NBK51784/GeneReviews®. Seattle (WA).
Human Blood	Detected and Quantified		0	5	uM	Newborn (0-30 days old)	Both	Normal	HMDB	BC Children's Hospital Biochemical Genetics Lab
Human Blood	Detected and Quantified		0	5	uM	Infant (1 - 3 months old)	Both	Normal	HMDB	BC Children's Hospital Biochemical Genetics Lab
Human Blood	Detected and Quantified		0	5	uM	Children (3 months - 6 years old)	Both	Normal	HMDB	BC Children's Hospital Biochemical Genetics Lab
Human Blood	Detected and Quantified		0	5	uM	Children (6 - 18 years old)	Both	Normal	HMDB	BC Children's Hospital Biochemical Genetics Lab
Human Urine	Detected and Quantified	<0.433			umol/mmol creatinine	Not Specified	Not Specified	Normal	HMDB	Geigy Scientific Tables, 8th Rev edition, pp. 130. Edited by C. Lentner, West Cadwell, N.J.: Medical education Div., Ciba-Geigy Corp. Basel, Switzerland c1981-1992.
Human Urine	Detected and Quantified	<1.70			umol/mmol creatinine	Adult (>18 years old)	Not Specified	Normal	HMDB	Mayo Clinic (https://neurology.testcatalog.org/show/AAPD)
Human Urine	Detected and Quantified	<2.71			umol/mmol creatinine	Children (1-13 years old)	Not Specified	Normal	HMDB	Mayo Clinic (https://neurology.testcatalog.org/show/AAPD)
Human Urine	Detected and Quantified	<4.19			umol/mmol creatinine	Children (1-13 years old)	Not Specified	Normal	HMDB	Mayo Clinic (https://neurology.testcatalog.org/show/AAPD)
Human Urine	Detected and Quantified	<5.43			umol/mmol creatinine	Children (1-13 years old)	Not Specified	Normal	HMDB	Mayo Clinic (https://neurology.testcatalog.org/show/AAPD)
Human Urine	Detected and Quantified	<7.81			umol/mmol creatinine	Adolescent (13-18 years old)	Not Specified	Normal	HMDB	Mayo Clinic (https://neurology.testcatalog.org/show/AAPD)
Human Urine	Detected and Quantified	<8.71			umol/mmol creatinine	Infant (0-1 year old)	Not Specified	Normal	HMDB	Mayo Clinic (https://neurology.testcatalog.org/show/AAPD)
Human Kidney	Detected but not Quantified					Not Specified	Not Specified	Normal	HMDB	34986597
Human Placenta	Detected but not Quantified					Not Specified	Not Specified	Normal	HMDB	34986597
Human Prostate	Detected but not Quantified					Not Specified	Not Specified	Normal	HMDB	34986597

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FooDB ID

Not Available

KNApSAcK ID

C00019688

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

439998

PDB ID

Not Available

ChEBI ID

15682

Food Biomarker Ontology

Not Available

References

Synthesis Reference

Not Available

General References

Glick NR, Snodgrass PJ, Schafer IA: Neonatal argininosuccinic aciduria with normal brain and kidney but absent liver argininosuccinate lyase activity. Am J Hum Genet. 1976 Jan;28(1):22-30. [PubMed:174426 ]
Fleisher LD, Rassin DK, Desnick RJ, Salwen HR, Rogers P, Bean M, Gaull GE: Argininosuccinic aciduria: prenatal studies in a family at risk. Am J Hum Genet. 1979 Jul;31(4):439-45. [PubMed:484552 ]
Michels VV, Beaudet AL: Arginase deficiency in multiple tissues in argininemia. Clin Genet. 1978 Jan;13(1):61-7. doi: 10.1111/j.1399-0004.1978.tb04128.x. [PubMed:624188 ]
Pelli N, Fensom AH, Slade C, Boa F, Mieli-Vergani G, Vergani D: Argininosuccinate lyase: a new autoantigen in liver disease. Clin Exp Immunol. 1998 Dec;114(3):455-61. doi: 10.1046/j.1365-2249.1998.00754.x. [PubMed:9844057 ]
Wasant P, Srisomsap C, Liammongkolkul S, Svasti J: Urea cycle disorders in Thai infants: a report of 5 cases. J Med Assoc Thai. 2002 Aug;85 Suppl 2:S720-31. [PubMed:12403252 ]
Kleijer WJ, Garritsen VH, Linnebank M, Mooyer P, Huijmans JG, Mustonen A, Simola KO, Arslan-Kirchner M, Battini R, Briones P, Cardo E, Mandel H, Tschiedel E, Wanders RJ, Koch HG: Clinical, enzymatic, and molecular genetic characterization of a biochemical variant type of argininosuccinic aciduria: prenatal and postnatal diagnosis in five unrelated families. J Inherit Metab Dis. 2002 Sep;25(5):399-410. doi: 10.1023/a:1020108002877. [PubMed:12408190 ]
Reid Sutton V, Pan Y, Davis EC, Craigen WJ: A mouse model of argininosuccinic aciduria: biochemical characterization. Mol Genet Metab. 2003 Jan;78(1):11-6. doi: 10.1016/s1096-7192(02)00206-8. [PubMed:12559843 ]
Au WL, Lim TC, Seow DC, Koh PL, Loh NK, Lim MS, Tan IK, Yee WC: Serial diffusion-weighted magnetic resonance imaging in adult-onset citrullinaemia. J Neurol Sci. 2003 May 15;209(1-2):101-4. doi: 10.1016/s0022-510x(02)00439-2. [PubMed:12686410 ]
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Showing metabocard for (N(omega)-L-arginino)succinic acid (MMDBc0033045)

MOL for #<Metabolite:0x00007fd0bc3d2b08>

3D MOL for #<Metabolite:0x00007fd0bc3d2b08>

3D SDF for #<Metabolite:0x00007fd0bc3d2b08>

3D-SDF for #<Metabolite:0x00007fd0bc3d2b08>

PDB for #<Metabolite:0x00007fd0bc3d2b08>

3D PDB for #<Metabolite:0x00007fd0bc3d2b08>

SMILES for #<Metabolite:0x00007fd0bc3d2b08>

INCHI for #<Metabolite:0x00007fd0bc3d2b08>

Structure for #<Metabolite:0x00007fd0bc3d2b08>

3D Structure for #<Metabolite:0x00007fd0bc3d2b08>