Mrv0541 02241222492D
16 17 0 0 1 0 999 V2000
-0.7145 -2.8875 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
0.0000 -2.4750 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0
0.7145 -2.8875 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
0.0000 -1.6500 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-0.7145 -1.2375 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
0.7145 -1.2375 0.0000 C 0 0 1 0 0 0 0 0 0 0 0 0
0.7145 -0.4125 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
1.4289 0.0000 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0
2.1434 -0.4125 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
2.8579 0.0000 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0
3.5724 -0.4125 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
3.5724 -1.2375 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0
2.8579 -1.6500 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
2.8579 -2.4750 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
2.1434 -1.2375 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
1.4289 -1.6500 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0
1 2 1 0 0 0 0
2 3 1 1 0 0 0
2 4 1 0 0 0 0
4 5 1 0 0 0 0
6 4 1 1 0 0 0
6 7 1 0 0 0 0
7 8 1 0 0 0 0
8 9 1 0 0 0 0
9 10 2 0 0 0 0
10 11 1 0 0 0 0
11 12 2 0 0 0 0
12 13 1 0 0 0 0
13 14 1 0 0 0 0
13 15 2 0 0 0 0
9 15 1 0 0 0 0
15 16 1 0 0 0 0
6 16 1 0 0 0 0
M END
> <DATABASE_ID>
MMDBc0033199
> <DATABASE_NAME>
MIME
> <SMILES>
C[C@H](O)C(O)[C@H]1CNC2=NC=NC(O)=C2N1
> <INCHI_IDENTIFIER>
InChI=1S/C9H14N4O3/c1-4(14)7(15)5-2-10-8-6(13-5)9(16)12-3-11-8/h3-5,7,13-15H,2H2,1H3,(H2,10,11,12,16)/t4-,5+,7?/m0/s1
> <INCHI_KEY>
XHZMOKNFPZDZBZ-YQGMFIQUSA-N
> <FORMULA>
C9H14N4O3
> <MOLECULAR_WEIGHT>
226.2325
> <EXACT_MASS>
226.106590334
> <JCHEM_ACCEPTOR_COUNT>
7
> <JCHEM_AVERAGE_POLARIZABILITY>
22.015641123936096
> <JCHEM_BIOAVAILABILITY>
1
> <JCHEM_DONOR_COUNT>
5
> <JCHEM_FORMAL_CHARGE>
0
> <JCHEM_GHOSE_FILTER>
0
> <JCHEM_IUPAC>
(2S)-1-[(6R)-4-hydroxy-5,6,7,8-tetrahydropteridin-6-yl]propane-1,2-diol
> <ALOGPS_LOGP>
-0.33
> <JCHEM_LOGP>
-1.1349783536666667
> <ALOGPS_LOGS>
-1.42
> <JCHEM_MDDR_LIKE_RULE>
0
> <JCHEM_NUMBER_OF_RINGS>
2
> <JCHEM_PHYSIOLOGICAL_CHARGE>
0
> <JCHEM_PKA>
13.899245874945983
> <JCHEM_PKA_STRONGEST_ACIDIC>
12.867526394034464
> <JCHEM_PKA_STRONGEST_BASIC>
1.276318374987519
> <JCHEM_POLAR_SURFACE_AREA>
110.53
> <JCHEM_REFRACTIVITY>
60.092600000000004
> <JCHEM_ROTATABLE_BOND_COUNT>
2
> <JCHEM_RULE_OF_FIVE>
1
> <ALOGPS_SOLUBILITY>
8.55e+00 g/l
> <JCHEM_TRADITIONAL_IUPAC>
(2S)-1-[(6R)-4-hydroxy-5,6,7,8-tetrahydropteridin-6-yl]propane-1,2-diol
> <JCHEM_VEBER_RULE>
0
$$$$