Record Information
Version1.0
StatusDetected and Quantified
Creation Date2021-11-23 23:16:52 UTC
Update Date2024-04-30 20:33:01 UTC
Metabolite IDMMDBc0047937
Metabolite Identification
Common NameMaleylacetoacetic acid
DescriptionMaleylacetoacetic acid, also known as 4-maleylacetoacetate, is an intermediate in the metabolism of tyrosine. Homogentisate 1,2-dioxygenase (HGD) is the enzyme which catalyzes the conversion of homogentisate into 4-maleylacetoacetate. HGD is involved in the catabolism of aromatic rings, more specifically in the breakdown of the amino acids tyrosine and phenylalanine.
Structure
Synonyms
ValueSource
4-MaleylacetoacetateChEBI
4-Maleylacetoacetic acidKegg
MaleylacetoacetateGenerator
(2Z)-4,6-Dioxo-2-octenedioic acidHMDB
Maleylacetoacetic acidHMDB
Molecular FormulaC8H8O6
Average Mass200.1455
Monoisotopic Mass200.032087988
IUPAC Name(2Z)-4,6-dioxooct-2-enedioic acid
Traditional Namemaleylacetoacetic acid
CAS Registry Number5698-52-2
SMILES
OC(=O)CC(=O)CC(=O)\C=C/C(O)=O
InChI Identifier
InChI=1S/C8H8O6/c9-5(1-2-7(11)12)3-6(10)4-8(13)14/h1-2H,3-4H2,(H,11,12)(H,13,14)/b2-1-
InChI KeyGACSIVHAIFQKTC-UPHRSURJSA-N