Record Information
Version1.0
StatusDetected and Quantified
Creation Date2020-09-24 20:43:31 UTC
Update Date2024-04-30 19:30:50 UTC
Metabolite IDMMDBc0057091
Metabolite Identification
Common Name(S)-3-Hydroxyisobutyric acid
DescriptionIndolylacryloylglycine, also known as IAG or indoleacrylic glycine, belongs to the class of organic compounds known as n-acyl-alpha amino acids. N-acyl-alpha amino acids are compounds containing an alpha amino acid which bears an acyl group at its terminal nitrogen atom. Indolylacryloylglycine (IAG) is a compound that is derived, in the same way as many other indole compounds, from tryptophan or indole compounds in the diet. Indolylacryloylglycine is a moderately basic compound (based on its pKa). Outside of the human body, Indolylacryloylglycine has been detected, but not quantified in, milk (cow). This could make indolylacryloylglycine a potential biomarker for the consumption of these foods. Indolylacryloylglycine is elevated in the urine of autistic children with gastrointestinal disturbances. It is likely a product of gut metabolism although the exact source is still unclear.
Structure
SynonymsNot Available
Molecular FormulaC4H8O3
Average Mass104.105
Monoisotopic Mass104.047344118
IUPAC NameNot Available
Traditional NameNot Available
CAS Registry Number26543-05-5
SMILESNot Available
InChI Identifier
Not Available
InChI KeyDBXBTMSZEOQQDU-YEQUQEJONA-N