MiMeDB: Showing metabocard for Farnesyl pyrophosphate (MMDBc0029519)

Not Available

Record Information

Version

1.0

Status

Detected and Quantified

Creation Date

2021-11-17 23:25:38 UTC

Update Date

2024-10-15 16:22:21 UTC

Metabolite ID

MMDBc0029519

Metabolite Identification

Common Name

Farnesyl pyrophosphate

Description

Farnesyl pyrophosphate is an intermediate in the HMG-CoA reductase pathway used by organisms in the biosynthesis of terpenes and terpenoids. -- Wikipedia

Structure

MOL 3D MOL SDF 3D SDF PDB 3D PDB SMILES InChI


  Mrv1652306222023512D          

 26 25  0  0  0  0            999 V2000
   -5.3625   -3.5724    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.3625   -2.1434    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8875   -0.7145    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4125    0.7145    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7125   -2.1434    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2375   -0.7145    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.1250   -2.8579    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8875   -2.1434    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6500   -1.4289    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4125   -0.7145    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.8250    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.2375    0.7145    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.9500   -2.8579    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4750   -1.4289    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.8250    4.2868    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.9520    3.9849    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.5230    3.1599    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.9520    1.7309    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.5230    2.5559    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.8250    1.4289    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.6500    2.8579    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.2375    3.5724    0.0000 P   0  0  0  0  0  0  0  0  0  0  0  0
    1.2375    2.1434    0.0000 P   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2375   -2.1434    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.2375   -0.7145    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
  7  5  1  0  0  0  0
  8  5  1  0  0  0  0
  9  6  1  0  0  0  0
 10  6  1  0  0  0  0
 12 11  1  0  0  0  0
 13  1  1  0  0  0  0
 13  2  1  0  0  0  0
 13  7  2  0  0  0  0
 14  3  1  0  0  0  0
 14  8  1  0  0  0  0
 14  9  2  0  0  0  0
 15  4  1  0  0  0  0
 15 10  1  0  0  0  0
 15 11  2  0  0  0  0
 21 12  1  0  0  0  0
 23 16  1  0  0  0  0
 23 17  1  0  0  0  0
 23 18  2  0  0  0  0
 23 22  1  0  0  0  0
 24 19  1  0  0  0  0
 24 20  2  0  0  0  0
 24 21  1  0  0  0  0
 24 22  1  0  0  0  0
 25  9  1  0  0  0  0
 26 11  1  0  0  0  0
M  END

HMDB0000961
     RDKit          3D
Farnesyl pyrophosphate
 52 51  0  0  0  0  0  0  0  0999 V2000
    6.4230    0.1068    2.1179 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.8021    0.6763    0.8043 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.2477    0.9937    0.5106 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.9122    0.9278   -0.1512 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.4791    0.6271    0.1045 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.0071   -0.3726   -0.9087 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5547   -0.7155   -0.6961 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.8734   -1.6898   -1.5874 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.8503   -0.1638    0.2818 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.4205   -0.5451    0.4377 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3990    0.7068    0.2875 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8424    0.5019    0.4157 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5093   -0.0389    1.6139 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.6084    0.8303   -0.6323 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.0843    0.6507   -0.5778 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.5011   -0.2336   -1.5922 O   0  0  0  0  0  0  0  0  0  0  0  0
   -6.1560   -0.4622   -1.5647 P   0  0  0  0  0  5  0  0  0  0  0  0
   -6.5541   -1.5528   -0.5842 O   0  0  0  0  0  0  0  0  0  0  0  0
   -6.7524   -0.9186   -3.0826 O   0  0  0  0  0  0  0  0  0  0  0  0
   -6.9556    0.9883   -1.1511 O   0  0  0  0  0  0  0  0  0  0  0  0
   -7.9336    0.7780    0.2040 P   0  0  0  0  0  5  0  0  0  0  0  0
   -7.4179   -0.2590    1.1490 O   0  0  0  0  0  0  0  0  0  0  0  0
   -8.0774    2.2827    1.0034 O   0  0  0  0  0  0  0  0  0  0  0  0
   -9.4855    0.2767   -0.3086 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.9058    0.9026    2.7188 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.7913   -0.8053    2.0244 H   0  0  0  0  0  0  0  0  0  0  0  0
    7.3494   -0.2290    2.6404 H   0  0  0  0  0  0  0  0  0  0  0  0
    8.4145    1.0482   -0.5717 H   0  0  0  0  0  0  0  0  0  0  0  0
    8.9067    0.2229    0.9256 H   0  0  0  0  0  0  0  0  0  0  0  0
    8.4674    1.9452    1.0444 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.1898    1.3413   -1.1040 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.3054    0.2569    1.1163 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.9265    1.5870   -0.0927 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.5674   -1.3165   -0.8025 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.1908   -0.0094   -1.9398 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.5095   -2.5829   -1.0295 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.0402   -1.2015   -2.1644 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.6081   -2.0394   -2.3412 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.2926    0.5463    0.9550 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.1125   -1.2625   -0.3500 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.2741   -1.0505    1.4015 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1224    1.1978   -0.6626 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0937    1.4305    1.0934 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7276   -0.2485    2.4004 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2070    0.6783    2.0885 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.0561   -0.9909    1.4217 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1606    1.2385   -1.5515 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.5466    1.6403   -0.7923 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3659    0.2330    0.3944 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.0256   -0.7905   -3.7414 H   0  0  0  0  0  0  0  0  0  0  0  0
   -7.8420    3.0130    0.3519 H   0  0  0  0  0  0  0  0  0  0  0  0
   -9.9975   -0.0772    0.4737 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  1  0
  2  4  2  3
  4  5  1  0
  5  6  1  0
  6  7  1  0
  7  8  1  0
  7  9  2  0
  9 10  1  0
 10 11  1  0
 11 12  1  0
 12 13  1  0
 12 14  2  0
 14 15  1  0
 15 16  1  0
 16 17  1  0
 17 18  2  0
 17 19  1  0
 17 20  1  0
 20 21  1  0
 21 22  2  0
 21 23  1  0
 21 24  1  0
  1 25  1  0
  1 26  1  0
  1 27  1  0
  3 28  1  0
  3 29  1  0
  3 30  1  0
  4 31  1  0
  5 32  1  0
  5 33  1  0
  6 34  1  0
  6 35  1  0
  8 36  1  0
  8 37  1  0
  8 38  1  0
  9 39  1  0
 10 40  1  0
 10 41  1  0
 11 42  1  0
 11 43  1  0
 13 44  1  0
 13 45  1  0
 13 46  1  0
 14 47  1  0
 15 48  1  0
 15 49  1  0
 19 50  1  0
 23 51  1  0
 24 52  1  0
M  END


  Mrv1652306222023512D          

 26 25  0  0  0  0            999 V2000
   -5.3625   -3.5724    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.3625   -2.1434    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8875   -0.7145    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4125    0.7145    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7125   -2.1434    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2375   -0.7145    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.1250   -2.8579    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8875   -2.1434    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6500   -1.4289    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4125   -0.7145    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.8250    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.2375    0.7145    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.9500   -2.8579    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4750   -1.4289    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.8250    4.2868    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.9520    3.9849    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.5230    3.1599    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.9520    1.7309    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.5230    2.5559    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.8250    1.4289    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.6500    2.8579    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.2375    3.5724    0.0000 P   0  0  0  0  0  0  0  0  0  0  0  0
    1.2375    2.1434    0.0000 P   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2375   -2.1434    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.2375   -0.7145    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
  7  5  1  0  0  0  0
  8  5  1  0  0  0  0
  9  6  1  0  0  0  0
 10  6  1  0  0  0  0
 12 11  1  0  0  0  0
 13  1  1  0  0  0  0
 13  2  1  0  0  0  0
 13  7  2  0  0  0  0
 14  3  1  0  0  0  0
 14  8  1  0  0  0  0
 14  9  2  0  0  0  0
 15  4  1  0  0  0  0
 15 10  1  0  0  0  0
 15 11  2  0  0  0  0
 21 12  1  0  0  0  0
 23 16  1  0  0  0  0
 23 17  1  0  0  0  0
 23 18  2  0  0  0  0
 23 22  1  0  0  0  0
 24 19  1  0  0  0  0
 24 20  2  0  0  0  0
 24 21  1  0  0  0  0
 24 22  1  0  0  0  0
 25  9  1  0  0  0  0
 26 11  1  0  0  0  0
M  END
> <DATABASE_ID>
MMDBc0029519

> <DATABASE_NAME>
MIME

> <SMILES>
[H]\C(CC\C(C)=C(/[H])COP(O)(=O)OP(O)(O)=O)=C(\C)CCC=C(C)C

> <INCHI_IDENTIFIER>
InChI=1S/C15H28O7P2/c1-13(2)7-5-8-14(3)9-6-10-15(4)11-12-21-24(19,20)22-23(16,17)18/h7,9,11H,5-6,8,10,12H2,1-4H3,(H,19,20)(H2,16,17,18)/b14-9+,15-11+

> <INCHI_KEY>
VWFJDQUYCIWHTN-YFVJMOTDSA-N

> <FORMULA>
C15H28O7P2

> <MOLECULAR_WEIGHT>
382.33

> <EXACT_MASS>
382.131027238

> <JCHEM_ACCEPTOR_COUNT>
5

> <JCHEM_ATOM_COUNT>
52

> <JCHEM_AVERAGE_POLARIZABILITY>
37.94192720134606

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
3

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
1

> <JCHEM_IUPAC>
{[hydroxy({[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]oxy})phosphoryl]oxy}phosphonic acid

> <ALOGPS_LOGP>
2.40

> <JCHEM_LOGP>
3.6167330606666663

> <ALOGPS_LOGS>
-3.68

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
0

> <JCHEM_PHYSIOLOGICAL_CHARGE>
-2

> <JCHEM_PKA>
3.2043406094078315

> <JCHEM_PKA_STRONGEST_ACIDIC>
1.7672186885241006

> <JCHEM_POLAR_SURFACE_AREA>
113.28999999999999

> <JCHEM_REFRACTIVITY>
96.73049999999999

> <JCHEM_ROTATABLE_BOND_COUNT>
11

> <JCHEM_RULE_OF_FIVE>
1

> <ALOGPS_SOLUBILITY>
8.07e-02 g/l

> <JCHEM_TRADITIONAL_IUPAC>
farnesyl diphosphate

> <JCHEM_VEBER_RULE>
0

$$$$

HMDB0000961
     RDKit          3D
Farnesyl pyrophosphate
 52 51  0  0  0  0  0  0  0  0999 V2000
    6.4230    0.1068    2.1179 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.8021    0.6763    0.8043 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.2477    0.9937    0.5106 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.9122    0.9278   -0.1512 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.4791    0.6271    0.1045 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.0071   -0.3726   -0.9087 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5547   -0.7155   -0.6961 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.8734   -1.6898   -1.5874 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.8503   -0.1638    0.2818 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.4205   -0.5451    0.4377 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3990    0.7068    0.2875 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8424    0.5019    0.4157 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5093   -0.0389    1.6139 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.6084    0.8303   -0.6323 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.0843    0.6507   -0.5778 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.5011   -0.2336   -1.5922 O   0  0  0  0  0  0  0  0  0  0  0  0
   -6.1560   -0.4622   -1.5647 P   0  0  0  0  0  5  0  0  0  0  0  0
   -6.5541   -1.5528   -0.5842 O   0  0  0  0  0  0  0  0  0  0  0  0
   -6.7524   -0.9186   -3.0826 O   0  0  0  0  0  0  0  0  0  0  0  0
   -6.9556    0.9883   -1.1511 O   0  0  0  0  0  0  0  0  0  0  0  0
   -7.9336    0.7780    0.2040 P   0  0  0  0  0  5  0  0  0  0  0  0
   -7.4179   -0.2590    1.1490 O   0  0  0  0  0  0  0  0  0  0  0  0
   -8.0774    2.2827    1.0034 O   0  0  0  0  0  0  0  0  0  0  0  0
   -9.4855    0.2767   -0.3086 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.9058    0.9026    2.7188 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.7913   -0.8053    2.0244 H   0  0  0  0  0  0  0  0  0  0  0  0
    7.3494   -0.2290    2.6404 H   0  0  0  0  0  0  0  0  0  0  0  0
    8.4145    1.0482   -0.5717 H   0  0  0  0  0  0  0  0  0  0  0  0
    8.9067    0.2229    0.9256 H   0  0  0  0  0  0  0  0  0  0  0  0
    8.4674    1.9452    1.0444 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.1898    1.3413   -1.1040 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.3054    0.2569    1.1163 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.9265    1.5870   -0.0927 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.5674   -1.3165   -0.8025 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.1908   -0.0094   -1.9398 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.5095   -2.5829   -1.0295 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.0402   -1.2015   -2.1644 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.6081   -2.0394   -2.3412 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.2926    0.5463    0.9550 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.1125   -1.2625   -0.3500 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.2741   -1.0505    1.4015 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1224    1.1978   -0.6626 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0937    1.4305    1.0934 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7276   -0.2485    2.4004 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2070    0.6783    2.0885 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.0561   -0.9909    1.4217 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1606    1.2385   -1.5515 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.5466    1.6403   -0.7923 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3659    0.2330    0.3944 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.0256   -0.7905   -3.7414 H   0  0  0  0  0  0  0  0  0  0  0  0
   -7.8420    3.0130    0.3519 H   0  0  0  0  0  0  0  0  0  0  0  0
   -9.9975   -0.0772    0.4737 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  1  0
  2  4  2  3
  4  5  1  0
  5  6  1  0
  6  7  1  0
  7  8  1  0
  7  9  2  0
  9 10  1  0
 10 11  1  0
 11 12  1  0
 12 13  1  0
 12 14  2  0
 14 15  1  0
 15 16  1  0
 16 17  1  0
 17 18  2  0
 17 19  1  0
 17 20  1  0
 20 21  1  0
 21 22  2  0
 21 23  1  0
 21 24  1  0
  1 25  1  0
  1 26  1  0
  1 27  1  0
  3 28  1  0
  3 29  1  0
  3 30  1  0
  4 31  1  0
  5 32  1  0
  5 33  1  0
  6 34  1  0
  6 35  1  0
  8 36  1  0
  8 37  1  0
  8 38  1  0
  9 39  1  0
 10 40  1  0
 10 41  1  0
 11 42  1  0
 11 43  1  0
 13 44  1  0
 13 45  1  0
 13 46  1  0
 14 47  1  0
 15 48  1  0
 15 49  1  0
 19 50  1  0
 23 51  1  0
 24 52  1  0
M  END

HEADER    PROTEIN                                 22-JUN-20   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   22-JUN-20         0                                  
HETATM    1  C   UNK     0     -10.010  -6.668   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0     -10.010  -4.001   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0      -5.390  -1.334   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0      -0.770   1.334   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0      -6.930  -4.001   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0      -2.310  -1.334   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0      -7.700  -5.335   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0      -5.390  -4.001   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0      -3.080  -2.667   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0      -0.770  -1.334   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0       1.540   0.000   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0       2.310   1.334   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0      -9.240  -5.335   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0      -4.620  -2.667   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0       0.000   0.000   0.000  0.00  0.00           C+0
HETATM   16  O   UNK     0       1.540   8.002   0.000  0.00  0.00           O+0
HETATM   17  O   UNK     0       3.644   7.438   0.000  0.00  0.00           O+0
HETATM   18  O   UNK     0       0.976   5.898   0.000  0.00  0.00           O+0
HETATM   19  O   UNK     0       3.644   3.231   0.000  0.00  0.00           O+0
HETATM   20  O   UNK     0       0.976   4.771   0.000  0.00  0.00           O+0
HETATM   21  O   UNK     0       1.540   2.667   0.000  0.00  0.00           O+0
HETATM   22  O   UNK     0       3.080   5.335   0.000  0.00  0.00           O+0
HETATM   23  P   UNK     0       2.310   6.668   0.000  0.00  0.00           P+0
HETATM   24  P   UNK     0       2.310   4.001   0.000  0.00  0.00           P+0
HETATM   25  H   UNK     0      -2.310  -4.001   0.000  0.00  0.00           H+0
HETATM   26  H   UNK     0       2.310  -1.334   0.000  0.00  0.00           H+0
CONECT    1   13                                                            
CONECT    2   13                                                            
CONECT    3   14                                                            
CONECT    4   15                                                            
CONECT    5    7    8                                                       
CONECT    6    9   10                                                       
CONECT    7    5   13                                                       
CONECT    8    5   14                                                       
CONECT    9    6   14   25                                                  
CONECT   10    6   15                                                       
CONECT   11   12   15   26                                                  
CONECT   12   11   21                                                       
CONECT   13    1    2    7                                                  
CONECT   14    3    8    9                                                  
CONECT   15    4   10   11                                                  
CONECT   16   23                                                            
CONECT   17   23                                                            
CONECT   18   23                                                            
CONECT   19   24                                                            
CONECT   20   24                                                            
CONECT   21   12   24                                                       
CONECT   22   23   24                                                       
CONECT   23   16   17   18   22                                             
CONECT   24   19   20   21   22                                             
CONECT   25    9                                                            
CONECT   26   11                                                            
MASTER        0    0    0    0    0    0    0    0   26    0   50    0
END

COMPND    HMDB0000961
HETATM    1  C1  UNL     1       6.423   0.107   2.118  1.00  0.00           C  
HETATM    2  C2  UNL     1       6.802   0.676   0.804  1.00  0.00           C  
HETATM    3  C3  UNL     1       8.248   0.994   0.511  1.00  0.00           C  
HETATM    4  C4  UNL     1       5.912   0.928  -0.151  1.00  0.00           C  
HETATM    5  C5  UNL     1       4.479   0.627   0.104  1.00  0.00           C  
HETATM    6  C6  UNL     1       4.007  -0.373  -0.909  1.00  0.00           C  
HETATM    7  C7  UNL     1       2.555  -0.716  -0.696  1.00  0.00           C  
HETATM    8  C8  UNL     1       1.873  -1.690  -1.587  1.00  0.00           C  
HETATM    9  C9  UNL     1       1.850  -0.164   0.282  1.00  0.00           C  
HETATM   10  C10 UNL     1       0.420  -0.545   0.438  1.00  0.00           C  
HETATM   11  C11 UNL     1      -0.399   0.707   0.288  1.00  0.00           C  
HETATM   12  C12 UNL     1      -1.842   0.502   0.416  1.00  0.00           C  
HETATM   13  C13 UNL     1      -2.509  -0.039   1.614  1.00  0.00           C  
HETATM   14  C14 UNL     1      -2.608   0.830  -0.632  1.00  0.00           C  
HETATM   15  C15 UNL     1      -4.084   0.651  -0.578  1.00  0.00           C  
HETATM   16  O1  UNL     1      -4.501  -0.234  -1.592  1.00  0.00           O  
HETATM   17  P1  UNL     1      -6.156  -0.462  -1.565  1.00  0.00           P  
HETATM   18  O2  UNL     1      -6.554  -1.553  -0.584  1.00  0.00           O  
HETATM   19  O3  UNL     1      -6.752  -0.919  -3.083  1.00  0.00           O  
HETATM   20  O4  UNL     1      -6.956   0.988  -1.151  1.00  0.00           O  
HETATM   21  P2  UNL     1      -7.934   0.778   0.204  1.00  0.00           P  
HETATM   22  O5  UNL     1      -7.418  -0.259   1.149  1.00  0.00           O  
HETATM   23  O6  UNL     1      -8.077   2.283   1.003  1.00  0.00           O  
HETATM   24  O7  UNL     1      -9.485   0.277  -0.309  1.00  0.00           O  
HETATM   25  H1  UNL     1       5.906   0.903   2.719  1.00  0.00           H  
HETATM   26  H2  UNL     1       5.791  -0.805   2.024  1.00  0.00           H  
HETATM   27  H3  UNL     1       7.349  -0.229   2.640  1.00  0.00           H  
HETATM   28  H4  UNL     1       8.414   1.048  -0.572  1.00  0.00           H  
HETATM   29  H5  UNL     1       8.907   0.223   0.926  1.00  0.00           H  
HETATM   30  H6  UNL     1       8.467   1.945   1.044  1.00  0.00           H  
HETATM   31  H7  UNL     1       6.190   1.341  -1.104  1.00  0.00           H  
HETATM   32  H8  UNL     1       4.305   0.257   1.116  1.00  0.00           H  
HETATM   33  H9  UNL     1       3.926   1.587  -0.093  1.00  0.00           H  
HETATM   34  H10 UNL     1       4.567  -1.316  -0.803  1.00  0.00           H  
HETATM   35  H11 UNL     1       4.191  -0.009  -1.940  1.00  0.00           H  
HETATM   36  H12 UNL     1       1.510  -2.583  -1.029  1.00  0.00           H  
HETATM   37  H13 UNL     1       1.040  -1.201  -2.164  1.00  0.00           H  
HETATM   38  H14 UNL     1       2.608  -2.039  -2.341  1.00  0.00           H  
HETATM   39  H15 UNL     1       2.293   0.546   0.955  1.00  0.00           H  
HETATM   40  H16 UNL     1       0.113  -1.263  -0.350  1.00  0.00           H  
HETATM   41  H17 UNL     1       0.274  -1.050   1.401  1.00  0.00           H  
HETATM   42  H18 UNL     1      -0.122   1.198  -0.663  1.00  0.00           H  
HETATM   43  H19 UNL     1      -0.094   1.430   1.093  1.00  0.00           H  
HETATM   44  H20 UNL     1      -1.728  -0.249   2.400  1.00  0.00           H  
HETATM   45  H21 UNL     1      -3.207   0.678   2.088  1.00  0.00           H  
HETATM   46  H22 UNL     1      -3.056  -0.991   1.422  1.00  0.00           H  
HETATM   47  H23 UNL     1      -2.161   1.238  -1.552  1.00  0.00           H  
HETATM   48  H24 UNL     1      -4.547   1.640  -0.792  1.00  0.00           H  
HETATM   49  H25 UNL     1      -4.366   0.233   0.394  1.00  0.00           H  
HETATM   50  H26 UNL     1      -6.026  -0.790  -3.741  1.00  0.00           H  
HETATM   51  H27 UNL     1      -7.842   3.013   0.352  1.00  0.00           H  
HETATM   52  H28 UNL     1      -9.998  -0.077   0.474  1.00  0.00           H  
CONECT    1    2   25   26   27
CONECT    2    3    4    4
CONECT    3   28   29   30
CONECT    4    5   31
CONECT    5    6   32   33
CONECT    6    7   34   35
CONECT    7    8    9    9
CONECT    8   36   37   38
CONECT    9   10   39
CONECT   10   11   40   41
CONECT   11   12   42   43
CONECT   12   13   14   14
CONECT   13   44   45   46
CONECT   14   15   47
CONECT   15   16   48   49
CONECT   16   17
CONECT   17   18   18   19   20
CONECT   19   50
CONECT   20   21
CONECT   21   22   22   23   24
CONECT   23   51
CONECT   24   52
END

HMDB0000961
     RDKit          3D
Farnesyl pyrophosphate
 52 51  0  0  0  0  0  0  0  0999 V2000
    6.4230    0.1068    2.1179 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.8021    0.6763    0.8043 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.2477    0.9937    0.5106 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.9122    0.9278   -0.1512 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.4791    0.6271    0.1045 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.0071   -0.3726   -0.9087 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5547   -0.7155   -0.6961 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.8734   -1.6898   -1.5874 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.8503   -0.1638    0.2818 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.4205   -0.5451    0.4377 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3990    0.7068    0.2875 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8424    0.5019    0.4157 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5093   -0.0389    1.6139 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.6084    0.8303   -0.6323 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.0843    0.6507   -0.5778 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.5011   -0.2336   -1.5922 O   0  0  0  0  0  0  0  0  0  0  0  0
   -6.1560   -0.4622   -1.5647 P   0  0  0  0  0  5  0  0  0  0  0  0
   -6.5541   -1.5528   -0.5842 O   0  0  0  0  0  0  0  0  0  0  0  0
   -6.7524   -0.9186   -3.0826 O   0  0  0  0  0  0  0  0  0  0  0  0
   -6.9556    0.9883   -1.1511 O   0  0  0  0  0  0  0  0  0  0  0  0
   -7.9336    0.7780    0.2040 P   0  0  0  0  0  5  0  0  0  0  0  0
   -7.4179   -0.2590    1.1490 O   0  0  0  0  0  0  0  0  0  0  0  0
   -8.0774    2.2827    1.0034 O   0  0  0  0  0  0  0  0  0  0  0  0
   -9.4855    0.2767   -0.3086 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.9058    0.9026    2.7188 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.7913   -0.8053    2.0244 H   0  0  0  0  0  0  0  0  0  0  0  0
    7.3494   -0.2290    2.6404 H   0  0  0  0  0  0  0  0  0  0  0  0
    8.4145    1.0482   -0.5717 H   0  0  0  0  0  0  0  0  0  0  0  0
    8.9067    0.2229    0.9256 H   0  0  0  0  0  0  0  0  0  0  0  0
    8.4674    1.9452    1.0444 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.1898    1.3413   -1.1040 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.3054    0.2569    1.1163 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.9265    1.5870   -0.0927 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.5674   -1.3165   -0.8025 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.1908   -0.0094   -1.9398 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.5095   -2.5829   -1.0295 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.0402   -1.2015   -2.1644 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.6081   -2.0394   -2.3412 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.2926    0.5463    0.9550 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.1125   -1.2625   -0.3500 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.2741   -1.0505    1.4015 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1224    1.1978   -0.6626 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0937    1.4305    1.0934 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7276   -0.2485    2.4004 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2070    0.6783    2.0885 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.0561   -0.9909    1.4217 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1606    1.2385   -1.5515 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.5466    1.6403   -0.7923 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3659    0.2330    0.3944 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.0256   -0.7905   -3.7414 H   0  0  0  0  0  0  0  0  0  0  0  0
   -7.8420    3.0130    0.3519 H   0  0  0  0  0  0  0  0  0  0  0  0
   -9.9975   -0.0772    0.4737 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  1  0
  2  4  2  3
  4  5  1  0
  5  6  1  0
  6  7  1  0
  7  8  1  0
  7  9  2  0
  9 10  1  0
 10 11  1  0
 11 12  1  0
 12 13  1  0
 12 14  2  0
 14 15  1  0
 15 16  1  0
 16 17  1  0
 17 18  2  0
 17 19  1  0
 17 20  1  0
 20 21  1  0
 21 22  2  0
 21 23  1  0
 21 24  1  0
  1 25  1  0
  1 26  1  0
  1 27  1  0
  3 28  1  0
  3 29  1  0
  3 30  1  0
  4 31  1  0
  5 32  1  0
  5 33  1  0
  6 34  1  0
  6 35  1  0
  8 36  1  0
  8 37  1  0
  8 38  1  0
  9 39  1  0
 10 40  1  0
 10 41  1  0
 11 42  1  0
 11 43  1  0
 13 44  1  0
 13 45  1  0
 13 46  1  0
 14 47  1  0
 15 48  1  0
 15 49  1  0
 19 50  1  0
 23 51  1  0
 24 52  1  0
M  END

Synonyms

Value	Source
(2E,6E)-Farnesol diphosphate	ChEBI
(2E,6E)-Farnesyl diphosphate	ChEBI
(2E,6E)-Farnesyl pyrophosphate	ChEBI
(all-e)-Farnesyl diphosphate	ChEBI
(e,e)-Farnesyl pyrophosphate	ChEBI
2-trans,6-trans-Farnesyl pyrophosphate	ChEBI
all-trans-Farnesyl pyrophosphate	ChEBI
Farnesyl diphosphate	ChEBI
trans,trans-Farnesyl diphosphate	ChEBI
trans-trans-Farnesyl diphosphate	ChEBI
2-trans,6-trans-Farnesyl diphosphate	Kegg
(2E,6E)-Farnesol diphosphoric acid	Generator
(2E,6E)-Farnesyl diphosphoric acid	Generator
(2E,6E)-Farnesyl pyrophosphoric acid	Generator
(all-e)-Farnesyl diphosphoric acid	Generator
(e,e)-Farnesyl pyrophosphoric acid	Generator
2-trans,6-trans-Farnesyl pyrophosphoric acid	Generator
all-trans-Farnesyl pyrophosphoric acid	Generator
Farnesyl diphosphoric acid	Generator
trans,trans-Farnesyl diphosphoric acid	Generator
trans-trans-Farnesyl diphosphoric acid	Generator
2-trans,6-trans-Farnesyl diphosphoric acid	Generator
Farnesyl pyrophosphoric acid	Generator
(e,e)-Farnesyl diphosphate	HMDB
Farnesyl-PP	HMDB
trans-Farnesyl pyrophosphate	HMDB
trans-trans-Farnesyl pyrophosphate	HMDB
Farnesyl pyrophosphate, (e,e)-isomer	HMDB
Farnesyl pyrophosphate, (e,Z)-isomer	HMDB
Farnesyl pyrophosphate, (Z,e)-isomer	HMDB
Farnesyl pyrophosphate, (Z,Z)-isomer	HMDB
Farnesylpyrophosphate	HMDB

Molecular Formula

C₁₅H₂₈O₇P₂

Average Mass

382.33

Monoisotopic Mass

382.131027238

IUPAC Name

{[hydroxy({[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]oxy})phosphoryl]oxy}phosphonic acid

Traditional Name

farnesyl diphosphate

CAS Registry Number

13058-04-3

SMILES

[H]\C(CC\C(C)=C(/[H])COP(O)(=O)OP(O)(O)=O)=C(\C)CCC=C(C)C

InChI Identifier

InChI=1S/C15H28O7P2/c1-13(2)7-5-8-14(3)9-6-10-15(4)11-12-21-24(19,20)22-23(16,17)18/h7,9,11H,5-6,8,10,12H2,1-4H3,(H,19,20)(H2,16,17,18)/b14-9+,15-11+

InChI Key

VWFJDQUYCIWHTN-YFVJMOTDSA-N

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as sesquiterpenoids. These are terpenes with three consecutive isoprene units.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Prenol lipids

Sub Class

Sesquiterpenoids

Direct Parent

Sesquiterpenoids

Alternative Parents

Substituents

Farsesane sesquiterpenoid
Sesquiterpenoid
Organic pyrophosphate
Isoprenoid phosphate
Monoalkyl phosphate
Alkyl phosphate
Phosphoric acid ester
Organic phosphoric acid derivative
Organic oxygen compound
Organic oxide
Hydrocarbon derivative
Organooxygen compound
Aliphatic acyclic compound

Molecular Framework

Aliphatic acyclic compounds

External Descriptors

farnesyl diphosphate (CHEBI:17407 )
Acyclic farnesane sesquiterpenoids (C00448 )
Farnesenes (C00448 )
Acyclic farnesane sesquiterpenoids (LMPR0103010002 )

Functional Ontology

Not Available

Physical Properties

State

Solid

Predicted Properties

Property	Value	Source
Water Solubility	0.081 g/L	ALOGPS
logP	2.4	ALOGPS
logP	3.62	ChemAxon
logS	-3.7	ALOGPS
pKa (Strongest Acidic)	1.77	ChemAxon
Physiological Charge	-2	ChemAxon
Hydrogen Acceptor Count	5	ChemAxon
Hydrogen Donor Count	3	ChemAxon
Polar Surface Area	113.29 Å²	ChemAxon
Rotatable Bond Count	11	ChemAxon
Refractivity	96.73 m³·mol⁻¹	ChemAxon
Polarizability	37.94 Å³	ChemAxon
Number of Rings	0	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	Yes	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

Spectra

Spectrum Type	Description	Splash Key	Deposition Date	View
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive	splash10-004j-7943000000-ab6d749700f510a94133	2016-09-22	View Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive	Not Available	2021-10-12	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - n/a 26V, negative	splash10-014i-0090000000-09efa5f4e481376eae3d	2020-07-21	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - Orbitrap 11V, negative	splash10-001i-2009000000-b2358e50ee86b2ebccb5	2020-07-22	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - Orbitrap 14V, negative	splash10-004i-9004000000-b255d40b3beef0ddd16f	2020-07-22	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - Orbitrap 16V, negative	splash10-004i-9001000000-64cd48aa93040d775977	2020-07-22	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - Orbitrap 19V, negative	splash10-004i-9000000000-84a4e8d938e03661128e	2020-07-22	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - Orbitrap 25V, negative	splash10-004i-9000000000-eb2e768f7c19af669f74	2020-07-22	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - n/a 26V, negative	splash10-03di-0209000000-651c59dc3e732ea880d7	2020-07-22	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - n/a 26V, negative	splash10-0a4i-0900000000-ae4be9bde4ed56cfa99b	2020-07-22	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - n/a 26V, positive	splash10-0002-0294000000-7019f71a6e4f542dddae	2020-07-22	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 10V, Positive	splash10-0pc0-1469000000-e3fd27c0418d0977f84e	2015-09-15	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 20V, Positive	splash10-0a4i-6791000000-1ca128d2b96287a5b2f1	2015-09-15	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 40V, Positive	splash10-0q29-9820000000-3277fbdf16e288ab1142	2015-09-15	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 10V, Negative	splash10-001i-0409000000-f8bbf786ee9d33cb48d4	2015-09-15	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 20V, Negative	splash10-004i-9501000000-8d060d3ceac94de45b8d	2015-09-15	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 40V, Negative	splash10-004i-9000000000-a265a369e6802359a7df	2015-09-15	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 10V, Negative	splash10-001i-0009000000-ea5bda9906940e9694b2	2021-09-23	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 20V, Negative	splash10-001i-2409000000-4b044bb59695723b85bd	2021-09-23	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 40V, Negative	splash10-056r-9600000000-a090357e0efeb6192936	2021-09-23	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 10V, Positive	splash10-001i-0019000000-66a0a5510c1d34aea230	2021-09-24	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 20V, Positive	splash10-114i-0394000000-89ab3170c9695823fb2f	2021-09-24	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 40V, Positive	splash10-05rs-6900000000-7b5163a81d3cbdf1feb4	2021-09-24	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 100 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 1000 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 200 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 300 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 400 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 500 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 600 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 700 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 800 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 900 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)		2022-08-20	View Spectrum

Biological Properties

Cellular Locations

Cytoplasm
Endoplasmic reticulum
Extracellular
Membrane
Peroxisome

Biospecimen Locations

Blood
Feces
Neuron
Testis

Tissue Locations

Neuron
Testis

Associated OMIM IDs

114500 (Colorectal cancer)
610247 (Eosinophilic esophagitis)

Human Proteins and Enzymes

Protein ID	Protein Name	Protein Type	Uniprot ID	Species
MMDBp0191930	Squalene synthase	Unknown	P37268	Homo sapiens
MMDBp0192549	Geranylgeranyl pyrophosphate synthase	Enzyme	O95749	Homo sapiens
MMDBp0192550	Farnesyl pyrophosphate synthase	Enzyme	P14324	Homo sapiens
MMDBp0193174	Protoheme IX farnesyltransferase, mitochondrial	Unknown	Q12887	Homo sapiens
MMDBp0193286	Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha	Enzyme	P49354	Homo sapiens
MMDBp0195924	Dehydrodolichyl diphosphate synthase	Enzyme	Q86SQ9	Homo sapiens
MMDBp0196226	Protein farnesyltransferase subunit beta	Enzyme	P49356	Homo sapiens
MMDBp0196783	Decaprenyl-diphosphate synthase subunit 2	Unknown	Q86YH6
MMDBp0196789	Decaprenyl-diphosphate synthase subunit 1	Unknown	Q5T2R2

Human Pathways

Pathways

Name	SMPDB/PathBank
Mevalonate Pathway

Metabolic Reactions

Reactions

Reaction ID	Precursor	Product	Enzyme	Data Source	Reference
MMDBr0000825	Farnesyl pyrophosphate	All trans decaprenyl diphosphate	Not Available	VMH; KEGG	16262699
MMDBr0001375	Geranyl-PP	Farnesyl pyrophosphate	farnesyl diphosphate synthase	VMH; KEGG	30371894
MMDBr0002165	Farnesyl pyrophosphate	squalene	farnesyl-diphosphate farnesyltransferase 1	VMH; KEGG	30371894
MMDBr0002475	Farnesyl pyrophosphate	presqualene diphosphate	farnesyl-diphosphate farnesyltransferase 1	VMH	11108725 1527001 17180682 7864626 8509416
MMDBr0004747	Dimethylallylpyrophosphate	2-trans,6-trans,10-trans-Geranylgeranyl diphosphate	Not Available	VMH	9054372 9741684
MMDBr0007409	Farnesyl pyrophosphate	2-trans,6-trans,10-trans-Geranylgeranyl diphosphate	Not Available	VMH	30371894
MMDBr0007410	Farnesyl pyrophosphate	Trans,Trans,Cis-Geranylgeranyl Diphosphate	Not Available	VMH	30371894
MMDBr0007458	Geranyl-PP	Farnesyl pyrophosphate	Not Available	VMH; KEGG	30371894
MMDBr0007863	Farnesyl pyrophosphate	Heme O	Not Available	VMH	30371894
MMDBr0007880	Farnesyl pyrophosphate	all-trans-Hexaprenyl diphosphate	Not Available	VMH	30371894
MMDBr0007989	Farnesyl pyrophosphate	Undecaprenyl diphosphate	Not Available	VMH	30371894
MMDBr0008390	squalene	Farnesyl pyrophosphate	Not Available	VMH	30371894
MMDBr0009527	presqualene diphosphate	Farnesyl pyrophosphate	farnesyl-diphosphate farnesyltransferase 1	VMH; KEGG	30371894
MMDBr0009538	Trans,Trans,Cis-Geranylgeranyl Diphosphate	Dimethylallylpyrophosphate	farnesyl diphosphate synthase	VMH	30371894

Health Effects and Bioactivity

Health Outcome/Bioactivity	Metabolite Response/Effect	Evidence Type	Host and Biospecimen	Data Source	Reference

Microbial Sources

Superkingdom/Kingdom	Phylum	Total species	Hosts and Body Sites	Microbial Links
Bacteria	Proteobacteria	468	Human feces; Human sputum; Human ; Human unknown; Pig ; Human pleural fluid plaque; Human dental plaque; Human nasal swab; Human stool; Human feces; pleural fluid plaque; bal; Chicken ; Cattle ; Rat ; Turkey ; Sheep ; Dog ; American dog tick ; River trout	Unknown; Metabolic reconstruction
Bacteria	Firmicutes	438	Human feces; Human pleural fluid plaque; Pig ; Human sputum; Human ; Human subgingival plaque; Human saliva; Human urine; Human mucosa; Human supragingival plaque; Cattle ; Human stool; Catfish	Metabolic reconstruction
Bacteria	Actinobacteria	186	Human feces; Human sputum; Human bronchial brush; Human nasopharyngeal swab; Human pleural fluid plaque; Human dental plaque; Human ; Human supragingival plaque; Human mucosa; Human subgingival plaque; Human saliva; Cattle	Metabolic reconstruction
Bacteria	Verrucomicrobia	2	Human ; Human feces	Metabolic reconstruction
Bacteria	Bacteroidetes	131	Human feces; Human appendix biopsy; Human ; Human stool; Human saliva; Human supragingival plaque; Human subgingival plaque; Human gastric fluid; Human urine	Metabolic reconstruction
Bacteria	Synergistetes	4	Human feces	Metabolic reconstruction
Bacteria	Spirochaetes	7	Human feces; Human	Metabolic reconstruction
Archaea	Thaumarchaeota	1		Metabolic reconstruction
Bacteria	Fusobacteria	20	Human feces; Human	Metabolic reconstruction
Archaea	Euryarchaeota	5		Metabolic reconstruction
Bacteria	Candidatus melainabacteria	1	Human feces	Metabolic reconstruction
Bacteria	Planctomycetes	2	Human feces	Metabolic reconstruction
Archaea	Crenarchaeota	1		Metabolic reconstruction
Bacteria	Tenericutes	2	Human feces	Metabolic reconstruction
Eukaryota/Fungi	Ascomycota	89	Human feces; Human saliva; Human supragingival plaque	Unknown
Eukaryota/Fungi	Basidiomycota	16
Bacteria	Cyanobacteria	33	Human
Archaea/Archaea	Euryarchaeota	11		Metabolic reconstruction
Eukaryota/Fungi	Mucoromycota	1
Archaea/Archaea	Crenarchaeota	18		Metabolic reconstruction
Viruses/Bamfordvirae	Nucleocytoviricota	5
Bacteria	Aquificae	1
Bacteria	Chloroflexi	3
Bacteria	Deinococcus-thermus	4
Archaea/Archaea	Korarchaeota	1
Bacteria	Acidobacteria	2
Bacteria	Chlamydiae	1	Human
Bacteria	nah	1
Archaea/Archaea	Thaumarchaeota	1		Metabolic reconstruction

Exposure Sources

Source Type	Species	Data Source	Reference
Animal	Laminaria	FooDB	Manually Annotated
Animal	Haliotis	FooDB	Manually Annotated
Animal	Strombidae	FooDB	Manually Annotated
Animal	Clupea harengus harengus	FooDB	Manually Annotated
Animal	Undaria pinnatifida	FooDB	Manually Annotated
Animal	Peprilus triacanthus	FooDB	Manually Annotated
Animal	Rhodophyta	FooDB	Manually Annotated
Animal	Myoxocephalus	FooDB	Manually Annotated
Animal	Eucheuma	FooDB	Manually Annotated
Animal	Saccharina japonica	FooDB	Manually Annotated
Animal	Spirulina	FooDB	Manually Annotated
Animal	Lota lota	FooDB	Manually Annotated
Animal	Porphyra umbilicalis	FooDB	Manually Annotated
Animal	Chondrus crispus	FooDB	Manually Annotated
Plant		FooDB	Manually Annotated
Plant	Laurus nobilis	FooDB	Manually Annotated
Plant	Auricularia auricula-judae	FooDB	Manually Annotated
Plant	Attalea speciosa	FooDB	Manually Annotated
Plant	Juglans ailanthifolia	FooDB	Manually Annotated
Plant	Melissa officinalis	FooDB	Manually Annotated
Plant	Hippophae rhamnoides	FooDB	Manually Annotated
Plant	Polygonum alpinum	FooDB	Manually Annotated
Plant	Brassica juncea	FooDB	Manually Annotated
Plant	Pediomelum esculentum	FooDB	Manually Annotated
Plant	Spinacia oleracea	FooDB	Manually Annotated
Plant	Auricularia polytricha	FooDB	Manually Annotated
Plant	Camellia oleifera	FooDB	Manually Annotated
Plant	Vaccinium corymbosum	FooDB	Manually Annotated
Plant	Chrysanthemum coronarium	FooDB	Manually Annotated
Plant	Eleocharis dulcis	FooDB	Manually Annotated
Plant	Thymus vulgaris	FooDB	Manually Annotated
Plant	Actinidia chinensis	FooDB	Manually Annotated
Plant	Carica papaya	FooDB	Manually Annotated
Plant	Pimenta dioica	FooDB	Manually Annotated
Plant	Medicago sativa	FooDB	Manually Annotated
Plant	Vigna mungo	FooDB	Manually Annotated
Plant	Rubus arcticus	FooDB	Manually Annotated
Plant	Agaricus bisporus	FooDB	Manually Annotated
Plant	Cajanus cajan	FooDB	Manually Annotated
Plant	Rumex articus	FooDB	Manually Annotated
Plant	Origanum majorana	FooDB	Manually Annotated
Plant	Armoracia rusticana	FooDB	Manually Annotated
Plant	Hibiscus sabdariffa	FooDB	Manually Annotated
Plant	Benincasa hispida	FooDB	Manually Annotated
Plant	Prunus persica	FooDB	Manually Annotated
Plant	Canarium ovatum	FooDB	Manually Annotated
Plant	Ribes aureum var. villosum	FooDB	Manually Annotated
Plant	Cucurbita pepo var. cylindrica	FooDB	Manually Annotated
Plant	Brassica oleracea var. gemmifera	FooDB	Manually Annotated
Plant	Foeniculum vulgare	FooDB	Manually Annotated
Plant	Phoenix dactylifera	FooDB	Manually Annotated
Plant	Vaccinium macrocarpon	FooDB	Manually Annotated
Plant	Arctium lappa	FooDB	Manually Annotated
Plant	Brassica oleracea var. gongylodes	FooDB	Manually Annotated
Plant		FooDB	Manually Annotated
Plant	Juglans cinerea	FooDB	Manually Annotated
Plant	Prunus cerasus	FooDB	Manually Annotated
Plant	Eruca vesicaria ssp. sativa	FooDB	Manually Annotated
Plant	Rosmarinus officinalis	FooDB	Manually Annotated
Plant	Artocarpus altilis	FooDB	Manually Annotated
Plant	Citrus x paradisi	FooDB	Manually Annotated
Plant	Vigna unguiculata	FooDB	Manually Annotated
Plant	Cynara scolymus	FooDB	Manually Annotated
Plant	Cyathea	FooDB	Manually Annotated
Plant	Metroxylon sagu	FooDB	Manually Annotated
Plant	Vitis rotundifolia	FooDB	Manually Annotated
Plant	Brosimum alicastrum	FooDB	Manually Annotated
Plant	Ficus carica	FooDB	Manually Annotated
Plant	Lentinus edodes	FooDB	Manually Annotated
Plant	Psidium cattleianum	FooDB	Manually Annotated
Plant	Beta vulgaris var. rubra	FooDB	Manually Annotated
Plant	Castanea mollissima	FooDB	Manually Annotated
Plant	Lepidium sativum	FooDB	Manually Annotated
Plant	Morus	FooDB	Manually Annotated
Plant	Helianthus tuberosus	FooDB	Manually Annotated
Plant	Phytolacca americana	FooDB	Manually Annotated
Plant	Grifola frondosa	FooDB	Manually Annotated
Plant	Vitis labrusca	FooDB	Manually Annotated
Plant	Tetragonia tetragonioides	FooDB	Manually Annotated
Plant	Artemisia vulgaris	FooDB	Manually Annotated
Plant	Cucumis metuliferus	FooDB	Manually Annotated
Plant	Nephelium lappaceum	FooDB	Manually Annotated
Plant	Myrica	FooDB	Manually Annotated
Plant	Castanea crenata	FooDB	Manually Annotated
Plant		FooDB	Manually Annotated
Plant	Corylus avellana	FooDB	Manually Annotated
Plant	Litchi chinensis	FooDB	Manually Annotated
Plant	Juglans regia	FooDB	Manually Annotated
Plant	Quercus	FooDB	Manually Annotated
Plant	Trigonella foenum-graecum	FooDB	Manually Annotated
Plant	Vaccinium angustifolium	FooDB	Manually Annotated
Plant	Malpighia emarginata	FooDB	Manually Annotated
Plant	Physalis	FooDB	Manually Annotated
Plant	Brassica oleracea var. sabauda	FooDB	Manually Annotated
Plant	Thelesperma	FooDB	Manually Annotated
Plant	Brassica napus	FooDB	Manually Annotated
Plant	Asparagus officinalis	FooDB	Manually Annotated
Plant	Chamerion angustifolium	FooDB	Manually Annotated
Plant	Levisticum officinale	FooDB	Manually Annotated
Plant	Pimpinella anisum	FooDB	Manually Annotated
Plant	Vaccinium elliottii	FooDB	Manually Annotated
Plant	Artemisia dracunculus	FooDB	Manually Annotated
Plant	Matricaria recutita	FooDB	Manually Annotated
Plant	Citrus aurantiifolia	FooDB	Manually Annotated
Plant	Ziziphus zizyphus	FooDB	Manually Annotated
Plant	Lactuca sativa	FooDB	Manually Annotated
Plant	Dimocarpus longan	FooDB	Manually Annotated
Plant	Eragrostis tef	FooDB	Manually Annotated
Plant	Salvia hispanica	FooDB	Manually Annotated
Plant	Pistacia vera	FooDB	Manually Annotated
Plant	Cynara cardunculus	FooDB	Manually Annotated
Plant	Vitellaria paradoxa	FooDB	Manually Annotated
Plant	Pangium edule	FooDB	Manually Annotated
Plant	Malus pumila	FooDB	Manually Annotated
Plant	Allium	FooDB	Manually Annotated
Plant	Brassica oleracea var. viridis	FooDB	Manually Annotated
Plant	Punica granatum	FooDB	Manually Annotated
Plant	Agave	FooDB	Manually Annotated
Plant	Hedysarum alpinum	FooDB	Manually Annotated
Plant	Diospyros	FooDB	Manually Annotated
Plant	Vigna aconitifolia	FooDB	Manually Annotated
Plant	Amaranthus	FooDB	Manually Annotated
Plant	Gossypium	FooDB	Manually Annotated
Plant		FooDB	Manually Annotated
Plant	Beta vulgaris	FooDB	Manually Annotated
Plant	Mammea americana	FooDB	Manually Annotated
Plant	Brassica alboglabra	FooDB	Manually Annotated
Plant	Annona squamosa	FooDB	Manually Annotated
Plant	Apium graveolens var. dulce	FooDB	Manually Annotated
Plant	Vitis	FooDB	Manually Annotated
Plant	Xanthosoma sagittifolium	FooDB	Manually Annotated
Plant	Basella alba	FooDB	Manually Annotated
Plant	Cucumis sativus	FooDB	Manually Annotated
Plant	Citrus latifolia	FooDB	Manually Annotated
Plant	Carya illinoinensis	FooDB	Manually Annotated
Plant	Capsicum baccatum var. baccatum	FooDB	Manually Annotated
Plant	Byrsonima crassifolia	FooDB	Manually Annotated
Plant	Capsicum pubescens	FooDB	Manually Annotated
Plant	Cinnamomum aromaticum	FooDB	Manually Annotated
Plant	Ribes rubrum	FooDB	Manually Annotated
Plant	Crateva religiosa	FooDB	Manually Annotated
Plant		FooDB	Manually Annotated
Plant	Vitis aestivalis	FooDB	Manually Annotated
Plant	Brassica rapa var. chinensis	FooDB	Manually Annotated
Plant	Eugenia javanica	FooDB	Manually Annotated
Plant	Portulaca oleracea	FooDB	Manually Annotated
Plant	Ipomoea batatas	FooDB	Manually Annotated
Plant	Mentha arvensis	FooDB	Manually Annotated
Plant	Pastinaca sativa	FooDB	Manually Annotated
Plant	Cucurbita maxima	FooDB	Manually Annotated
Plant	Vaccinium stamineum	FooDB	Manually Annotated
Plant	Solanum lycopersicum var. cerasiforme	FooDB	Manually Annotated
Plant	Chenopodium album	FooDB	Manually Annotated
Plant	Psophocarpus tetragonolobus	FooDB	Manually Annotated
Plant	Allium ampeloprasum	FooDB	Manually Annotated
Plant	Brassica oleracea	FooDB	Manually Annotated
Plant	Sechium edule	FooDB	Manually Annotated
Plant	Lactuca sativa l. var. longifolia	FooDB	Manually Annotated
Plant	Grataegosorbus mitschurinii	FooDB	Manually Annotated
Plant	Diospyros virginiana	FooDB	Manually Annotated
Plant	Origanum x majoricum	FooDB	Manually Annotated
Plant	Rubus x loganobaccus	FooDB	Manually Annotated
Plant	Tragopogon porrifolius	FooDB	Manually Annotated
Plant	Taraxacum officinale	FooDB	Manually Annotated
Plant	Rumex	FooDB	Manually Annotated
Plant	Allium ascalonicum	FooDB	Manually Annotated
Plant	Curcuma longa	FooDB	Manually Annotated
Plant	Rubus chamaemorus	FooDB	Manually Annotated
Plant	Elettaria cardamomum	FooDB	Manually Annotated
Plant	Citrullus lanatus var. fistulosus	FooDB	Manually Annotated
Plant	Ananas comosus	FooDB	Manually Annotated
Plant	Persea americana	FooDB	Manually Annotated
Plant	Amelanchier alnifolia	FooDB	Manually Annotated
Plant	Eugenia uniflora	FooDB	Manually Annotated
Plant	Annona reticulata	FooDB	Manually Annotated
Plant	Cichorium intybus	FooDB	Manually Annotated
Plant	Sesbania bispinosa	FooDB	Manually Annotated
Plant	Chenopodium quinoa	FooDB	Manually Annotated
Plant	Brassica oleracea var. botrytis	FooDB	Manually Annotated
Plant	Ribes x nidigrolaria	FooDB	Manually Annotated
Plant	Garcinia mangostana	FooDB	Manually Annotated
Plant	Cucumis melo	FooDB	Manually Annotated
Plant	Dioscorea pentaphylla	FooDB	Manually Annotated
Plant	Corchorus olitorius	FooDB	Manually Annotated
Plant	Juglans nigra	FooDB	Manually Annotated
Plant	Lathyrus sativus	FooDB	Manually Annotated
Plant	Allium tuberosum	FooDB	Manually Annotated
Plant	Cinnamomum verum	FooDB	Manually Annotated
Plant	Glycine max	FooDB	Manually Annotated
Plant	Gaylussacia baccata	FooDB	Manually Annotated
Plant	Petasites japonicus	FooDB	Manually Annotated
Plant	Prunus tomentosa	FooDB	Manually Annotated
Plant	Ocimum basilicum	FooDB	Manually Annotated
Plant	Mentha x piperita	FooDB	Manually Annotated
Plant	Maranta arundinacea	FooDB	Manually Annotated
Plant	Matteuccia struthiopteris	FooDB	Manually Annotated
Plant	Cucurbita moschata	FooDB	Manually Annotated
Plant	Macadamia	FooDB	Manually Annotated
Plant	Tilia	FooDB	Manually Annotated
Plant	Citrus limon	FooDB	Manually Annotated
Plant	Vaccinium myrtilloides	FooDB	Manually Annotated
Plant	Capsicum annuum var. annuum	FooDB	Manually Annotated
Plant	Apium graveolens var. rapaceum	FooDB	Manually Annotated
Plant	Papaver	FooDB	Manually Annotated
Plant	Rosa	FooDB	Manually Annotated
Plant	Nelumbo	FooDB	Manually Annotated
Plant	Brassica oleracea var. conica	FooDB	Manually Annotated
Plant	Sesamum orientale	FooDB	Manually Annotated
Plant	Annona cherimola	FooDB	Manually Annotated
Plant	Brassica rapa var. pekinensis	FooDB	Manually Annotated
Plant	Brassica rapa	FooDB	Manually Annotated
Plant	Lippia graveolens	FooDB	Manually Annotated
Plant	Prunus	FooDB	Manually Annotated
Plant	Capparis spinosa	FooDB	Manually Annotated
Plant	Citrus sinensis	FooDB	Manually Annotated
Plant	Lens culinaris	FooDB	Manually Annotated
Plant	Vaccinium deliciosum	FooDB	Manually Annotated
Plant	Phaseolus lunatus	FooDB	Manually Annotated
Plant	Artocarpus heterophyllus	FooDB	Manually Annotated
Plant	Prunus virginiana	FooDB	Manually Annotated
Plant	Musa acuminata	FooDB	Manually Annotated
Plant	Citrullus lanatus	FooDB	Manually Annotated
Plant	Linum usitatissimum	FooDB	Manually Annotated
Plant	Vigna unguiculata ssp. unguiculata	FooDB	Manually Annotated
Plant	Macadamia tetraphylla	FooDB	Manually Annotated
Plant	Phyllostachys edulis	FooDB	Manually Annotated
Plant	Lagenaria siceraria	FooDB	Manually Annotated
Plant	Prunus domestica	FooDB	Manually Annotated
Plant	Prunus armeniaca	FooDB	Manually Annotated
Plant	Carum carvi	FooDB	Manually Annotated
Plant	Allium schoenoprasum	FooDB	Manually Annotated
Plant	Carissa macrocarpa	FooDB	Manually Annotated
Plant	Citrus reticulata	FooDB	Manually Annotated
Plant	Satureja hortensis	FooDB	Manually Annotated
Plant	Averrhoa carambola	FooDB	Manually Annotated
Plant	Brassica rapa var. rapa	FooDB	Manually Annotated
Plant	Sorbus aucuparia	FooDB	Manually Annotated
Plant	Anethum graveolens	FooDB	Manually Annotated
Plant	Nelumbo nucifera	FooDB	Manually Annotated
Plant	Coriandrum sativum	FooDB	Manually Annotated
Plant	Bertholletia excelsa	FooDB	Manually Annotated
Plant	Brassica oleracea var. costata	FooDB	Manually Annotated
Plant	Panax	FooDB	Manually Annotated
Plant	Ceratonia siliqua	FooDB	Manually Annotated
Plant	Cymbopogon citratus	FooDB	Manually Annotated
Plant	Luffa aegyptiaca	FooDB	Manually Annotated
Plant	Anacardium occidentale	FooDB	Manually Annotated
Plant	Carthamus tinctorius	FooDB	Manually Annotated
Plant	Rubus occidentalis	FooDB	Manually Annotated
Plant	Vigna umbellata	FooDB	Manually Annotated
Plant	Cicer arietinum	FooDB	Manually Annotated
Plant	Allium fistulosum	FooDB	Manually Annotated
Plant	Capsicum	FooDB	Manually Annotated
Plant	Vaccinium alaskaense	FooDB	Manually Annotated
Plant	Lupinus	FooDB	Manually Annotated
Plant	Tilia cordata	FooDB	Manually Annotated
Plant	Prunus persica var. nucipersica	FooDB	Manually Annotated
Plant	Camellia sinensis	FooDB	Manually Annotated
Plant	Durio zibethinus	FooDB	Manually Annotated
Plant	Eriobotrya japonica	FooDB	Manually Annotated
Plant	Solanum lycopersicum var. lycopersicum	FooDB	Manually Annotated
Plant	Brassica napus var. pabularia	FooDB	Manually Annotated
Plant	Oenothera biennis	FooDB	Manually Annotated
Plant	Diospyros kaki	FooDB	Manually Annotated
Plant	Ribes glandulosum	FooDB	Manually Annotated
Plant	Virola surinamensis	FooDB	Manually Annotated
Plant	Verbena officinalis	FooDB	Manually Annotated
Plant	Phaseolus vulgaris	FooDB	Manually Annotated
Plant	Theobroma cacao	FooDB	Manually Annotated
Plant	Daucus carota ssp. sativus	FooDB	Manually Annotated
Plant	Vaccinium oxycoccos	FooDB	Manually Annotated
Plant	Rumex acetosa	FooDB	Manually Annotated
Plant	Syzygium aromaticum	FooDB	Manually Annotated
Plant	Pyrus pyrifolia	FooDB	Manually Annotated
Plant	Vaccinium myrtillus	FooDB	Manually Annotated
Plant	Vaccinium parvifolium	FooDB	Manually Annotated
Plant	Aloysia triphylla	FooDB	Manually Annotated
Plant	Brassica oleracea var. capitata	FooDB	Manually Annotated
Plant	Capsicum chinense	FooDB	Manually Annotated
Plant	Vicia faba	FooDB	Manually Annotated
Plant	Vaccinium reticulatum	FooDB	Manually Annotated
Plant	Solanum quitoense	FooDB	Manually Annotated
Plant	Ginkgo biloba	FooDB	Manually Annotated
Plant	Theobroma grandiflorum	FooDB	Manually Annotated
Plant	Vigna unguiculata ssp. cylindrica	FooDB	Manually Annotated
Plant	Flammulina velutipes	FooDB	Manually Annotated
Plant	Satureja montana	FooDB	Manually Annotated
Plant		FooDB	Manually Annotated
Plant	Vitis vinifera	FooDB	Manually Annotated
Plant	Citrus japonica	FooDB	Manually Annotated
Plant	Prunus avium	FooDB	Manually Annotated
Plant	Perideridia oregana	FooDB	Manually Annotated
Plant	Vaccinium arboreum	FooDB	Manually Annotated
Plant	Pouteria sapota	FooDB	Manually Annotated
Plant	Wasabia japonica	FooDB	Manually Annotated
Plant	Piper nigrum	FooDB	Manually Annotated
Plant	Origanum onites	FooDB	Manually Annotated
Plant	Capsicum annuum	FooDB	Manually Annotated
Plant	Origanum vulgare	FooDB	Manually Annotated
Plant	Viburnum edule	FooDB	Manually Annotated
Plant	Dioscorea	FooDB	Manually Annotated
Plant	Brassica oleracea var. italica	FooDB	Manually Annotated
Plant	Momordica charantia	FooDB	Manually Annotated
Plant	Vaccinium uliginosum	FooDB	Manually Annotated
Plant	Castanea	FooDB	Manually Annotated
Plant	Rubus ursinus x idaeus	FooDB	Manually Annotated
Plant	Pleurotus ostreatus	FooDB	Manually Annotated
Plant	Cirsium	FooDB	Manually Annotated
Plant	Solanum melongena	FooDB	Manually Annotated
Plant	Opuntia	FooDB	Manually Annotated
Plant	Raphanus sativus var. sativus	FooDB	Manually Annotated
Plant	Colocasia esculenta	FooDB	Manually Annotated
Plant	Prunus persica var. persica	FooDB	Manually Annotated
Plant	Anthriscus cerefolium	FooDB	Manually Annotated
Plant	Nuphar lutea	FooDB	Manually Annotated
Plant	Myristica fragrans	FooDB	Manually Annotated
Plant	Pachyrhizus erosus	FooDB	Manually Annotated
Plant	Lupinus albus	FooDB	Manually Annotated
Plant	Cichorium endivia	FooDB	Manually Annotated
Plant	Apium graveolens	FooDB	Manually Annotated
Plant	Elaeis	FooDB	Manually Annotated
Plant	Cinnamomum	FooDB	Manually Annotated
Plant	Ribes uva-crispa	FooDB	Manually Annotated
Plant	Feijoa sellowiana	FooDB	Manually Annotated
Plant	Dysphania ambrosioides	FooDB	Manually Annotated
Plant	Raphanus sativus var. niger	FooDB	Manually Annotated
Plant	Photinia melanocarpa	FooDB	Manually Annotated
Plant	Salvia officinalis	FooDB	Manually Annotated
Plant	Rheum rhabarbarum	FooDB	Manually Annotated
Plant	Vaccinium	FooDB	Manually Annotated
Plant	Lablab purpureus	FooDB	Manually Annotated
Plant	Crocus sativus	FooDB	Manually Annotated
Plant	Citrus maxima	FooDB	Manually Annotated
Plant	Syzygium jambos	FooDB	Manually Annotated
Plant	Salix pulchra	FooDB	Manually Annotated
Plant	Castanea sativa	FooDB	Manually Annotated
Plant	Cydonia oblonga	FooDB	Manually Annotated
Plant	Annona muricata	FooDB	Manually Annotated
Plant	Fagus	FooDB	Manually Annotated
Plant	Cucurbita	FooDB	Manually Annotated
Plant	Opuntia cochenillifera	FooDB	Manually Annotated
Plant	Vaccinium ovatum	FooDB	Manually Annotated
Plant	Cocos nucifera	FooDB	Manually Annotated
Plant	Phaseolus coccineus	FooDB	Manually Annotated
Plant	Thymus pulegioides	FooDB	Manually Annotated
Plant	Tamarindus indica	FooDB	Manually Annotated
Plant	Mespilus germanica	FooDB	Manually Annotated
Plant	Brassica rapa var. perviridis	FooDB	Manually Annotated
Plant	Cucurbita pepo var. cylindrica	FooDB	Manually Annotated
Plant	Mentha aquatica	FooDB	Manually Annotated
Plant	Salvia elegans	FooDB	Manually Annotated
Plant	Mentha	FooDB	Manually Annotated
Plant	Sagittaria latifolia	FooDB	Manually Annotated
Plant	Solanum tuberosum	FooDB	Manually Annotated
Plant	Olea europaea	FooDB	Manually Annotated
Plant	Sambucus	FooDB	Manually Annotated
Plant	Pinus	FooDB	Manually Annotated
Plant	Psidium guajava	FooDB	Manually Annotated
Plant	Syzygium cumini	FooDB	Manually Annotated
Plant	Tilia tomentosa	FooDB	Manually Annotated
Plant	Typha angustifolia	FooDB	Manually Annotated
Plant	Daucus carota	FooDB	Manually Annotated
Plant	Empetrum nigrum	FooDB	Manually Annotated
Plant	Valerianella locusta	FooDB	Manually Annotated
Plant	Myrica rubra	FooDB	Manually Annotated
Plant	Vaccinium vitis-idaea	FooDB	Manually Annotated
Plant	Vaccinium angustifolium x vaccinium corymbosum	FooDB	Manually Annotated
Plant	Sisymbrium	FooDB	Manually Annotated
Plant	Vanilla	FooDB	Manually Annotated
Plant	Carya	FooDB	Manually Annotated
Plant	Brassica oleracea l. var. capitata l. f. alba dc.	FooDB	Manually Annotated
Plant	Physalis philadelphica var. immaculata	FooDB	Manually Annotated
Plant	Vigna radiata	FooDB	Manually Annotated
Plant	Borago officinalis	FooDB	Manually Annotated
Plant	Raphanus sativus	FooDB	Manually Annotated
Plant	Prunus dulcis	FooDB	Manually Annotated
Plant	Hyssopus officinalis	FooDB	Manually Annotated
Plant	Manihot esculenta	FooDB	Manually Annotated
Plant	Beta vulgaris ssp. cicla	FooDB	Manually Annotated
Plant	Scorzonera hispanica	FooDB	Manually Annotated
Plant	Vigna unguiculata ssp. sesquipedalis	FooDB	Manually Annotated
Plant	Angelica keiskei	FooDB	Manually Annotated
Plant	Ipomoea aquatica	FooDB	Manually Annotated
Plant	Musa x paradisiaca	FooDB	Manually Annotated
Plant	Cuminum cyminum	FooDB	Manually Annotated
Plant	Rubus spectabilis	FooDB	Manually Annotated
Plant	Allium sativum	FooDB	Manually Annotated
Plant	Arachis hypogaea	FooDB	Manually Annotated
Plant	Rubus idaeus	FooDB	Manually Annotated
Plant	Cantharellus cibarius	FooDB	Manually Annotated
Plant	Sinapis alba	FooDB	Manually Annotated
Plant	Fragaria x ananassa	FooDB	Manually Annotated
Plant	Pyrus communis	FooDB	Manually Annotated
Plant	Brassica ruvo	FooDB	Manually Annotated
Plant	Apium graveolens var. secalinum	FooDB	Manually Annotated
Plant	Morus nigra	FooDB	Manually Annotated
Plant	Solanum lycopersicum	FooDB	Manually Annotated
Plant	Abelmoschus esculentus	FooDB	Manually Annotated
Plant	Moringa oleifera	FooDB	Manually Annotated
Plant	Pinus edulis	FooDB	Manually Annotated
Plant	Passiflora edulis	FooDB	Manually Annotated
Plant	Opuntia macrorhiza	FooDB	Manually Annotated
Plant	Vigna angularis	FooDB	Manually Annotated
Plant	Manilkara zapota	FooDB	Manually Annotated
Plant	Cucurbita pepo var. clypeata	FooDB	Manually Annotated
Plant	Helianthus annuus	FooDB	Manually Annotated
Plant	Mentha spicata	FooDB	Manually Annotated
Plant	Corylus	FooDB	Manually Annotated
Plant	Malus	FooDB	Manually Annotated
Plant	Pisum sativum	FooDB	Manually Annotated
Plant	Sambucus nigra	FooDB	Manually Annotated
Plant	Allium cepa	FooDB	Manually Annotated
Plant	Juglans	FooDB	Manually Annotated
Plant	Mangifera indica	FooDB	Manually Annotated
Plant	Petroselinum crispum	FooDB	Manually Annotated
Plant	Ribes nigrum	FooDB	Manually Annotated
Plant	Zingiber officinale	FooDB	Manually Annotated
Plant	Chamaemelum nobile	FooDB	Manually Annotated
Plant	Illicium verum	FooDB	Manually Annotated

Source Type	Activity	Data Source	Reference
Drugs	Antimicrobial	U.S. Environmental Protection Agency	CompTox
Cosmetics	Not Available	U.S. Environmental Protection Agency	CompTox
Domestics	Not Available	U.S. Environmental Protection Agency	CompTox

Host Biospecimen and Location

Host and Biospecimen	Status	Mean	Min	Max	Units	Age	Sex	Health Condition	Data Source	Reference
Human Feces	Detected but not Quantified								HMDB
Human Blood	Detected and Quantified	0.0086	0.0000	0.0170	uM	Adult (>18 years old)	Not Specified	Normal	HMDB	9324945
Human Neuron	Detected but not Quantified					Not Specified	Not Specified	Normal	HMDB	34986597
Human Testis	Detected but not Quantified					Not Specified	Not Specified	Normal	HMDB	34986597

External Links

HMDB ID

HMDB0000961

DrugBank ID

DB07780

Phenol Explorer Compound ID

Not Available

FooDB ID

KNApSAcK ID

Chemspider ID

KEGG Compound ID

BioCyc ID

BiGG ID

Wikipedia Link

Farnesyl pyrophosphate

METLIN ID

403

PubChem Compound

445713

PDB ID

Not Available

ChEBI ID

17407

Food Biomarker Ontology

Not Available

References

Synthesis Reference

Not Available

General References

Saisho Y, Morimoto A, Umeda T: Determination of farnesyl pyrophosphate in dog and human plasma by high-performance liquid chromatography with fluorescence detection. Anal Biochem. 1997 Oct 1;252(1):89-95. doi: 10.1006/abio.1997.2314. [PubMed:9324945 ]
Tacer KF, Haugen TB, Baltsen M, Debeljak N, Rozman D: Tissue-specific transcriptional regulation of the cholesterol biosynthetic pathway leads to accumulation of testis meiosis-activating sterol (T-MAS). J Lipid Res. 2002 Jan;43(1):82-9. [PubMed:11792726 ]
Fukuchi J, Song C, Ko AL, Liao S: Transcriptional regulation of farnesyl pyrophosphate synthase by liver X receptors. Steroids. 2003 Sep;68(7-8):685-91. doi: 10.1016/s0039-128x(03)00100-4. [PubMed:12957674 ]
Notarnicola M, Messa C, Cavallini A, Bifulco M, Tecce MF, Eletto D, Di Leo A, Montemurro S, Laezza C, Caruso MG: Higher farnesyl diphosphate synthase activity in human colorectal cancer inhibition of cellular apoptosis. Oncology. 2004;67(5-6):351-8. doi: 10.1159/000082918. [PubMed:15713990 ]
Argmann CA, Edwards JY, Sawyez CG, O'Neil CH, Hegele RA, Pickering JG, Huff MW: Regulation of macrophage cholesterol efflux through hydroxymethylglutaryl-CoA reductase inhibition: a role for RhoA in ABCA1-mediated cholesterol efflux. J Biol Chem. 2005 Jun 10;280(23):22212-21. doi: 10.1074/jbc.M502761200. Epub 2005 Apr 6. [PubMed:15817453 ]
Sanders JM, Song Y, Chan JM, Zhang Y, Jennings S, Kosztowski T, Odeh S, Flessner R, Schwerdtfeger C, Kotsikorou E, Meints GA, Gomez AO, Gonzalez-Pacanowska D, Raker AM, Wang H, van Beek ER, Papapoulos SE, Morita CT, Oldfield E: Pyridinium-1-yl bisphosphonates are potent inhibitors of farnesyl diphosphate synthase and bone resorption. J Med Chem. 2005 Apr 21;48(8):2957-63. doi: 10.1021/jm040209d. [PubMed:15828834 ]
Shellman YG, Ribble D, Miller L, Gendall J, Vanbuskirk K, Kelly D, Norris DA, Dellavalle RP: Lovastatin-induced apoptosis in human melanoma cell lines. Melanoma Res. 2005 Apr;15(2):83-9. doi: 10.1097/00008390-200504000-00001. [PubMed:15846140 ]
Reigard SA, Zahn TJ, Haworth KB, Hicks KA, Fierke CA, Gibbs RA: Interplay of isoprenoid and peptide substrate specificity in protein farnesyltransferase. Biochemistry. 2005 Aug 23;44(33):11214-23. doi: 10.1021/bi050725l. [PubMed:16101305 ]

Showing metabocard for Farnesyl pyrophosphate (MMDBc0029519)

MOL for #<Metabolite:0x00007fdb58332378>

3D MOL for #<Metabolite:0x00007fdb58332378>

3D SDF for #<Metabolite:0x00007fdb58332378>

3D-SDF for #<Metabolite:0x00007fdb58332378>

PDB for #<Metabolite:0x00007fdb58332378>

3D PDB for #<Metabolite:0x00007fdb58332378>

SMILES for #<Metabolite:0x00007fdb58332378>

INCHI for #<Metabolite:0x00007fdb58332378>

Structure for #<Metabolite:0x00007fdb58332378>

3D Structure for #<Metabolite:0x00007fdb58332378>