MiMeDB: Showing metabocard for UDP-Glucuronic acid (MMDBc0029638)

Not Available

Record Information

Version

1.0

Status

Detected and Quantified

Creation Date

2021-11-17 23:35:39 UTC

Update Date

2024-10-13 12:41:37 UTC

Metabolite ID

MMDBc0029638

Metabolite Identification

Common Name

UDP-Glucuronic acid

Description

UDP-Glucuronic acid is an intermediate in polymyxin resistance in E. coli. It is a substrate for UDP-GlcA C-4"-decarboxylase (gene name: arnA) which catalyzes the chemical reaction UDP-D-glucuronate + NAD+ -> UDP-beta-L-threo-pentapyranos-4-ulose + CO2 + NADH. In UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose), UDP-glucose 6-dehydrogenase converts UDP-alpha-D-glucose to UDP-Glucuronic acid (EcoCyc compound: UDP-GLUCURONATE).

Structure

MOL SDF PDB SMILES InChI

Synonyms

Value	Source
UDP-alpha-D-Glucuronate	ChEBI
UDP-D-Glucuronate	ChEBI
UDP-Glucuronate	ChEBI
UDPglucuronate	ChEBI
URIDINE-5'-diphosphATE-glucuronIC ACID	ChEBI
UDP-a-D-Glucuronate	Generator
UDP-a-D-Glucuronic acid	Generator
UDP-alpha-D-Glucuronic acid	Generator
UDP-Α-D-glucuronate	Generator
UDP-Α-D-glucuronic acid	Generator
UDP-D-Glucuronic acid	Generator
UDP-Glucuronic acid	Generator
UDPglucuronic acid	Generator
URIDINE-5'-diphosphate-glucuronate	Generator
URIDINE-5'-diphosphoric acid-glucuronic acid	Generator
Uridine diphosphate glucuronate	Generator
Uridine diphosphoric acid glucuronic acid	Generator
a-D-Glucopyranuronic acid 1->5'-ester with uridine 5'-(trihydrogen pyrophosphate)	HMDB
a-D-Glucopyranuronic acid ester with uridine 5'-pyrophosphate	HMDB
alpha-D-Glucopyranuronic acid 1-p'-ester with uridine 5'-(trihydrogen diphosphate)	HMDB
alpha-delta-Glucopyranuronic acid 1->5'-ester with uridine 5'-(trihydrogen pyrophosphate)	HMDB
alpha-delta-Glucopyranuronic acid 1-p'-ester with uridine 5'-(trihydrogen diphosphate)	HMDB
alpha-delta-Glucopyranuronic acid ester with uridine 5'-pyrophosphate	HMDB
Glucopyranuronic acid 1-ester with uridine 5'-pyrophosphate	HMDB
UDP Glucuronate	HMDB
UDP Glucuronic acid	HMDB
UDP-alpha-delta-Glucuronate	HMDB
UDP-delta-Glucuronate	HMDB
UDP-delta-Glucuronic acid	HMDB
UDP-GlcUA	HMDB
UDPGA	HMDB
UGA	HMDB
Uridine 5'-diphospho-a-D-glucuronate	HMDB
Uridine 5'-diphospho-a-D-glucuronic acid	HMDB
Uridine 5'-diphospho-alpha-delta-glucuronate	HMDB
Uridine 5'-diphospho-alpha-delta-glucuronic acid	HMDB
Uridine 5'-diphospho-glucuronic acid	HMDB
Uridine 5'-diphosphoglucuronate	HMDB
Uridine 5'-diphosphoglucuronic acid	HMDB
Uridine 5'-[3-(D-glucopyranosyloxyuronic acid) dihydrogen diphosphate]	HMDB
Uridine diphosphate-glucuronate	HMDB
Uridine diphospho-D-glucuronate	HMDB
Uridine diphospho-D-glucuronic acid	HMDB
Uridine diphospho-delta-glucuronate	HMDB
Uridine diphospho-delta-glucuronic acid	HMDB
Uridine diphosphoglucuronate	HMDB
Uridine diphosphoglucuronic acid	HMDB
Uridine pyrophosphoglucuronate	HMDB
Uridine pyrophosphoglucuronic acid	HMDB
Uridinediphosphoglucuronic acid	HMDB
Acid, UDP glucuronic	HMDB
Acid, uridine diphosphoglucuronic	HMDB
Glucuronic acid, UDP	HMDB
Diphosphoglucuronic acid, uridine	HMDB
Uridine 5'-diphospho-alpha-D-glucuronic acid	HMDB
Uridine 5'-diphospho-α-D-glucuronic acid	HMDB
Uridine 5’-diphospho-α-D-glucuronic acid	HMDB
Uridine 5’-diphosphoglucuronic acid	HMDB
Uridine diphosphate glucuronic acid	HMDB

Molecular Formula

C₁₅H₂₂N₂O₁₈P₂

Average Mass

580.2853

Monoisotopic Mass

580.034284934

IUPAC Name

Not Available

Traditional Name

Not Available

CAS Registry Number

2616-64-0

SMILES

Not Available

InChI Identifier

InChI=1S/C15H22N2O18P2/c18-5-1-2-17(15(26)16-5)12-9(22)6(19)4(32-12)3-31-36(27,28)35-37(29,30)34-14-10(23)7(20)8(21)11(33-14)13(24)25/h1-2,4,6-12,14,19-23H,3H2,(H,24,25)(H,27,28)(H,29,30)(H,16,18,26)/t4-,6-,7+,8+,9-,10-,11+,12-,14-/m1/s1

InChI Key

HDYANYHVCAPMJV-LXQIFKJMSA-N

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as gamma butyrolactones. Gamma butyrolactones are compounds containing a gamma butyrolactone moiety, which consists of an aliphatic five-member ring with four carbon atoms, one oxygen atom, and bears a ketone group on the carbon adjacent to the oxygen atom.

Kingdom

Organic compounds

Super Class

Organoheterocyclic compounds

Class

Lactones

Sub Class

Gamma butyrolactones

Direct Parent

Gamma butyrolactones

Alternative Parents

Substituents

Gamma butyrolactone
Tetrahydrofuran
Secondary alcohol
Carboxylic acid ester
1,2-diol
Oxacycle
Monocarboxylic acid or derivatives
Carboxylic acid derivative
Organic oxygen compound
Organic oxide
Hydrocarbon derivative
Organooxygen compound
Carbonyl group
Alcohol
Aliphatic heteromonocyclic compound

Molecular Framework

Aliphatic heteromonocyclic compounds

External Descriptors

diol (CHEBI:71176 )
butan-4-olide (CHEBI:71176 )

Functional Ontology

Not Available

Physical Properties

State

Expected Solid

Predicted Properties

Not Available

Spectra

Not Available

Biological Properties

Cellular Locations

Endoplasmic reticulum
Golgi apparatus

Biospecimen Locations

Feces
Liver
Placenta

Tissue Locations

Liver
Placenta

Associated OMIM IDs

114500 (Colorectal cancer)
610247 (Eosinophilic esophagitis)

Human Proteins and Enzymes

Protein ID	Protein Name	Protein Type	Uniprot ID	Species
MMDBp0192111	UDP-glucuronosyltransferase 2B28	Enzyme	Q9BY64	Homo sapiens
MMDBp0192118	UDP-glucuronosyltransferase 2B4	Enzyme	P06133	Homo sapiens
MMDBp0192135	UDP-glucuronosyltransferase 1-4	Enzyme	P22310	Homo sapiens
MMDBp0192136	UDP-glucuronosyltransferase 2B10	Enzyme	P36537	Homo sapiens
MMDBp0192137	UDP-glucuronosyltransferase 2B7	Enzyme	P16662	Homo sapiens
MMDBp0192138	UDP-glucuronosyltransferase 2B15	Enzyme	P54855	Homo sapiens
MMDBp0192139	UDP-glucuronosyltransferase 2A1	Enzyme	Q9Y4X1	Homo sapiens
MMDBp0192140	UDP-glucuronosyltransferase 1-1	Enzyme	P22309	Homo sapiens
MMDBp0192141	UDP-glucuronosyltransferase 1-9	Enzyme	O60656	Homo sapiens
MMDBp0192142	UDP-glucuronosyltransferase 1-8	Enzyme	Q9HAW9	Homo sapiens
MMDBp0192143	UDP-glucuronosyltransferase 1-3	Enzyme	P35503	Homo sapiens
MMDBp0192144	UDP-glucuronosyltransferase 1-10	Enzyme	Q9HAW8	Homo sapiens
MMDBp0192145	UDP-glucuronosyltransferase 2B17	Enzyme	O75795	Homo sapiens
MMDBp0192146	UDP-glucuronosyltransferase 1-6	Enzyme	P19224	Homo sapiens
MMDBp0192147	UDP-glucuronosyltransferase 1-5	Enzyme	P35504	Homo sapiens
MMDBp0192148	UDP-glucuronosyltransferase 2B11	Enzyme	O75310	Homo sapiens
MMDBp0192151	UDP-glucuronosyltransferase 1-7	Enzyme	Q9HAW7	Homo sapiens
MMDBp0192525	UDP-glucose 6-dehydrogenase	Unknown	O60701	Homo sapiens
MMDBp0192551	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3	Unknown	O94766	Homo sapiens
MMDBp0192552	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2	Unknown	Q9NPZ5	Homo sapiens
MMDBp0192553	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1	Unknown	Q9P2W7	Homo sapiens
MMDBp0192709	Chondroitin sulfate synthase 3	Unknown	Q70JA7	Homo sapiens
MMDBp0192710	Chondroitin sulfate synthase 2	Unknown	Q8IZ52	Homo sapiens
MMDBp0192711	Chondroitin sulfate synthase 1	Unknown	Q86X52	Homo sapiens
MMDBp0193208	Exostosin-1	Enzyme	Q16394	Homo sapiens
MMDBp0193209	Hyaluronan synthase 1	Unknown	Q92839	Homo sapiens
MMDBp0193211	Exostosin-2	Enzyme	Q93063	Homo sapiens
MMDBp0193216	Hyaluronan synthase 3	Unknown	O00219	Homo sapiens
MMDBp0193308	Hyaluronan synthase 2	Unknown	Q92819	Homo sapiens
MMDBp0193746	Chondroitin sulfate glucuronyltransferase	Enzyme	Q9P2E5	Homo sapiens
MMDBp0193842	UDP-glucuronic acid decarboxylase 1	Unknown	Q8NBZ7	Homo sapiens
MMDBp0194142	UDP-glucuronosyltransferase 2A3	Enzyme	Q6UWM9	Homo sapiens
MMDBp0195932	HCG2039726, isoform CRA_f	Enzyme	Q5DT02	Homo sapiens
MMDBp0195933	HCG2039726, isoform CRA_e	Enzyme	Q5DSZ6	Homo sapiens
MMDBp0195934	UDP glycosyltransferase 1 family polypeptide A7	Enzyme	Q5DSZ7	Homo sapiens
MMDBp0197010	UDP-glucuronosyltransferase 3A1	Unknown	Q6NUS8
MMDBp0197011	UDP-glucuronosyltransferase 3A2	Unknown	Q3SY77

Human Pathways

Pathways

Name	SMPDB/PathBank

Metabolic Reactions

Reactions

Reaction ID	Precursor	Product	Enzyme	Data Source	Reference
MMDBr0001416	Uridine diphosphate-N-acetylglucosamine	Hyaluronan biosynthesis, precursor 1	hyaluronan synthase 1	VMH	12512858 8651928 8798477 8798544 9083017
MMDBr0001417	Hyaluronan biosynthesis, precursor 1	Hyaluronic acid	hyaluronan synthase 1	VMH	12512858 8651928 8798477 8798544 9083017
MMDBr0002309	UDP-Glucuronic acid	D-Glucuronate 1-phosphate	Not Available	VMH	30371894
MMDBr0002312	Uridine diphosphate glucose	UDP-Glucuronic acid	UDP-glucose 6-dehydrogenase	VMH; KEGG	30371894
MMDBr0002317	UDP-Glucuronic acid	UDP-D-Xylose	UDP-glucuronate decarboxylase 1	VMH; KEGG	30371894
MMDBr0002318	UDP-Glucuronic acid	D-Glucuronic acid	Not Available	VMH; KEGG	30371894
MMDBr0002327	Bilirubin	Mono(Glucosyluronic Acid)Bilirubin	UDP glucuronosyltransferase 1 family, polypeptide A1	VMH	7945246
MMDBr0002328	Estrone	Estrone glucuronide	UDP glucuronosyltransferase 1 family, polypeptide A1	VMH	15117964 9295054
MMDBr0002329	Bilirubin	Bilirubin diglucuronide	UDP glucuronosyltransferase 1 family, polypeptide A1	VMH	15117964 9295054
MMDBr0002330	Androsterone	Androsterone glucuronide	UDP glucuronosyltransferase 1 family, polypeptide A1	VMH	11300766 14643063 15117964 9295054
MMDBr0002331	Testosterone	Testosterone glucuronide	UDP glucuronosyltransferase 1 family, polypeptide A1	VMH	11300766 15117964 9295054
MMDBr0002332	all-trans-Retinoic acid	Retinoyl b-glucuronide	UDP glucuronosyltransferase 1 family, polypeptide A1	VMH	15117964 9295054
MMDBr0002333	13-cis-Retinoic acid	13-Cis-Retinoyl Glucuronide	UDP glucuronosyltransferase 1 family, polypeptide A1	VMH	14704335 1503811
MMDBr0002334	Estradiol	17-beta-Estradiol-3-glucuronide	UDP glucuronosyltransferase 1 family, polypeptide A1	VMH	15117964 9295054
MMDBr0002335	Etiocholanolone	Etiocholanolone glucuronide	UDP glucuronosyltransferase 1 family, polypeptide A1	VMH	15117964 9295054
MMDBr0002336	Estriol	Estriol-16-Glucuronide	UDP glucuronosyltransferase 1 family, polypeptide A1	VMH	11300766 15117964 8333863 9295054
MMDBr0002337	Dihydrotestosterone	5-alpha-Dihydrotestosterone glucuronide	UDP glucuronosyltransferase 2 family, polypeptide B28	VMH	11300766
MMDBr0003908	3,5-Diiodo-L-Thyronine	3,5-Diiodo-L-Thyronine-Beta-D-Glucuronoside	UDP glucuronosyltransferase 1 family, polypeptide A8	VMH	3988241 7263841 8333863
MMDBr0003909	3,5-Diiodo-L-Thyronine	3,5-Diiodo-L-Thyronine-Beta-D-Glucuronoside	UDP glucuronosyltransferase 1 family, polypeptide A10	VMH	3988241 7263841 8333863
MMDBr0003910	Thyroxine	3,5,3,5-Tetraiodo-L-Thyronine-Beta-D-Glucuronoside	UDP glucuronosyltransferase 1 family, polypeptide A8	VMH	7263841 8405382
MMDBr0003911	Thyroxine	3,5,3,5-Tetraiodo-L-Thyronine-Beta-D-Glucuronoside	UDP glucuronosyltransferase 1 family, polypeptide A10	VMH	7263841 8405382
MMDBr0003912	3,3,5 - Triiodothyronine	3,3,5-Triiodo-L-Thyronine-Beta-D-Glucuronoside	UDP glucuronosyltransferase 1 family, polypeptide A8	VMH	1339448 7263841 8405382
MMDBr0003913	3,3,5 - Triiodothyronine	3,3,5-Triiodo-L-Thyronine-Beta-D-Glucuronoside	UDP glucuronosyltransferase 1 family, polypeptide A10	VMH	1339448 7263841 8405382
MMDBr0003914	Liothyronine	3,5,3-Triiodo-L-Thyronine-Beta-D-Glucuronoside	UDP glucuronosyltransferase 1 family, polypeptide A8	VMH	7263841 8405382
MMDBr0003915	Liothyronine	3,5,3-Triiodo-L-Thyronine-Beta-D-Glucuronoside	UDP glucuronosyltransferase 1 family, polypeptide A10	VMH	7263841 8405382
MMDBr0003916	3,3-Diiodo-L-Thyronine	3,3-Diiodo-L-Thyronine-Beta-D-Glucuronoside	UDP glucuronosyltransferase 1 family, polypeptide A8	VMH	7263841
MMDBr0003917	3,3-Diiodo-L-Thyronine	3,3-Diiodo-L-Thyronine-Beta-D-Glucuronoside	UDP glucuronosyltransferase 1 family, polypeptide A10	VMH	7263841
MMDBr0003918	3,5,3,5-Tetraiodothyroacetate	3,5,3,5-Tetraiodothyroacetate-Beta-D-Glucuronoside	UDP glucuronosyltransferase 1 family, polypeptide A8	VMH	3090812 7364927 8070342 9633995
MMDBr0003919	3,5,3,5-Tetraiodothyroacetate	3,5,3,5-Tetraiodothyroacetate-Beta-D-Glucuronoside	UDP glucuronosyltransferase 1 family, polypeptide A10	VMH	3090812 7364927 8070342 9633995
MMDBr0003920	3,3,5-Triiodothyroacetate	3,3,5-Triiodothyroacetate-Beta-D-Glucuronoside	UDP glucuronosyltransferase 1 family, polypeptide A8	VMH	2229315 8070342 9633995
MMDBr0003921	3,3,5-Triiodothyroacetate	3,3,5-Triiodothyroacetate-Beta-D-Glucuronoside	UDP glucuronosyltransferase 1 family, polypeptide A10	VMH	2229315 8070342 9633995
MMDBr0003924	3,5,3-Triiodothyroacetate	3,5,3-Triiodothyroacetate-Beta-D-Glucuronoside	UDP glucuronosyltransferase 1 family, polypeptide A8	VMH	2229315 8070342 9633995
MMDBr0003925	3,5,3-Triiodothyroacetate	3,5,3-Triiodothyroacetate-Beta-D-Glucuronoside	UDP glucuronosyltransferase 1 family, polypeptide A10	VMH	2229315 8070342 9633995
MMDBr0003926	3,5-Diiodothyroacetate	3,5-Diiodothyroacetate-Beta-D-Glucuronoside	UDP glucuronosyltransferase 1 family, polypeptide A8	VMH	2627761 7410532 8070342 9633995
MMDBr0003927	3,5-Diiodothyroacetate	3,5-Diiodothyroacetate-Beta-D-Glucuronoside	UDP glucuronosyltransferase 1 family, polypeptide A10	VMH	2627761 7410532 8070342 9633995
MMDBr0004187	13-cis-Retinoic acid	13-Cis-Retinoyl Glucuronide	UDP glucuronosyltransferase 1 family, polypeptide A8	VMH	10702251
MMDBr0004188	4-Hydroxy-All-Trans-Retinyl Acetate	Rac-4-Hydroxy-4-O-(Beta-D-Glucuronide)-All-Trans-Retinyl Acetate	UDP glucuronosyltransferase 1 family, polypeptide A8	VMH	10702251
MMDBr0004189	4-Hydroxy-All-Trans-Retinyl Acetate	Rac-4-Hydroxy-4-O-(Beta-D-Glucuronide)-All-Trans-Retinyl Acetate	UDP glucuronosyltransferase 1 family, polypeptide A10	VMH	10702251
MMDBr0004190	4-Oxo-9-Cis-Retinoate	4-Oxo-9-Cis-Retinoyl-Beta-Glucuronide	UDP glucuronosyltransferase 1 family, polypeptide A8	VMH	8295481
MMDBr0004191	4-Oxo-9-Cis-Retinoate	4-Oxo-9-Cis-Retinoyl-Beta-Glucuronide	UDP glucuronosyltransferase 1 family, polypeptide A10	VMH	8295481
MMDBr0004254	Alpha-CEHC	Alpha-Cehc-Glucuronide	UDP glucuronosyltransferase 1 family, polypeptide A8	VMH	10191290
MMDBr0004255	Alpha-CEHC	Alpha-Cehc-Glucuronide	UDP glucuronosyltransferase 1 family, polypeptide A10	VMH	10191290
MMDBr0004256	gamma-CEHC	Gama-Cehc-Glucuronide	UDP glucuronosyltransferase 1 family, polypeptide A8	VMH	10191290
MMDBr0004257	gamma-CEHC	Gama-Cehc-Glucuronide	UDP glucuronosyltransferase 1 family, polypeptide A10	VMH	10191290
MMDBr0004310	2-Hydroxyamino-3,8-Dimethylimidazo[4,5-F]Quinoxaline	2-Hydroxyamino-Meiqx-N2-(Beta-1-Glucosiduronyl)-2-Hydroxyamino-3,8-Dimethylimidazo[4,5-F]Quinoxaline	UDP glucuronosyltransferase 1 family, polypeptide A8	VMH	10537291
MMDBr0004311	2-Hydroxyamino-3,8-Dimethylimidazo[4,5-F]Quinoxaline	2-Hydroxyamino-Meiqx-N2-(Beta-1-Glucosiduronyl)-2-Hydroxyamino-3,8-Dimethylimidazo[4,5-F]Quinoxaline	UDP glucuronosyltransferase 1 family, polypeptide A10	VMH	10537291
MMDBr0004671	12,13-DHOME	12-Hydroxy-13-O-D-Glucuronoside-Octadec-9Z-Enoate	UDP glucuronosyltransferase 1 family, polypeptide A8	VMH	10933884
MMDBr0004672	12,13-DHOME	12-Hydroxy-13-O-D-Glucuronoside-Octadec-9Z-Enoate	UDP glucuronosyltransferase 1 family, polypeptide A10	VMH	10933884
MMDBr0004673	9,10-DHOME	9-Hydroxy-10-O-D-Glucuronoside-12Z-Octadecenoate	UDP glucuronosyltransferase 1 family, polypeptide A8	VMH	10933884
MMDBr0004674	9,10-DHOME	9-Hydroxy-10-O-D-Glucuronoside-12Z-Octadecenoate	UDP glucuronosyltransferase 1 family, polypeptide A10	VMH	10933884
MMDBr0004676	12,13-DHOME	12-O-D-Glucuronoside-13-Hydroxyoctadec-9Z-Enoate	UDP glucuronosyltransferase 1 family, polypeptide A8	VMH	10933884
MMDBr0004677	12,13-DHOME	12-O-D-Glucuronoside-13-Hydroxyoctadec-9Z-Enoate	UDP glucuronosyltransferase 1 family, polypeptide A10	VMH	10933884
MMDBr0004678	9,10-DHOME	10-Hydroxy-Octadec-12Z-Enoate-9-Beta-D-Glucuronide	UDP glucuronosyltransferase 1 family, polypeptide A8	VMH	10933884
MMDBr0004679	9,10-DHOME	10-Hydroxy-Octadec-12Z-Enoate-9-Beta-D-Glucuronide	UDP glucuronosyltransferase 1 family, polypeptide A10	VMH	10933884
MMDBr0005431	Mono(Glucosyluronic Acid)Bilirubin	Bilirubin diglucuronide	UDP glucuronosyltransferase 1 family, polypeptide A1	VMH	30371894
MMDBr0006784	Bilirubin	Mono(Glucosyluronic Acid)Bilirubin	Not Available	VMH	30371894
MMDBr0007990	Uridine diphosphate glucose	UDP-Glucuronic acid	Not Available	VMH	30371894
MMDBr0009063	Dopamine	Dopamine glucuronide	chondroitin polymerizing factor	VMH	30371894
MMDBr0009064	Dopamine	Dopamine-3-O-Glucuronide	chondroitin polymerizing factor	VMH	30371894
MMDBr0010273	UDP-Glucuronic acid	UDP-D-Xylose	UDP-glucuronate decarboxylase 1	VMH; KEGG	30371894
MMDBr0010405	L-Kynurenine	3-Hydroxykynurenine-O-Beta-D-Glucoside	Not Available	VMH	30371894
MMDBr0010492	2,2,2-Trichloroethanol	Trichloroethanol glucuronide	UDP glucuronosyltransferase 1 family, polypeptide A1	VMH; KEGG	30371894
MMDBr0010516	4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanol	4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol glucuronide	UDP glucuronosyltransferase 1 family, polypeptide A1	VMH; KEGG	30371894
MMDBr0010517	4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanol	Nnal-N-Glucuronide	UDP glucuronosyltransferase 1 family, polypeptide A1	VMH; KEGG	30371894
MMDBr0010822	5,6-Epoxy-13-Cis-Retinoate	Rac-5,6-Epoxy-Retinoyl-Beta-D-Glucuronide	UDP glucuronosyltransferase 1 family, polypeptide A1	VMH	30371894
MMDBr0012380	Deoxycholic acid	Deoxycholic acid 3-glucuronide	UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus	VMH	30371894
MMDBr0012381	Deoxycholic acid	Deoxycholic acid 3-glucuronide	UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus	VMH	30371894
MMDBr0012423	Acetaminophen	Acetaminophen Glucuronide	UDP glucuronosyltransferase 1 family, polypeptide A6	VMH	30371894

Health Effects and Bioactivity

Health Outcome/Bioactivity	Metabolite Response/Effect	Evidence Type	Host and Biospecimen	Data Source	Reference

Microbial Sources

Superkingdom/Kingdom	Phylum	Total species	Hosts and Body Sites	Microbial Links
Bacteria	Proteobacteria	237	Human feces; Human sputum; Human ; Human unknown; Pig ; Human pleural fluid plaque; Human dental plaque; Human nasal swab; Human stool; Human feces; pleural fluid plaque; bal; River trout	Unknown; Metabolic reconstruction
Bacteria	Firmicutes	230	Pig ; Human feces; Human sputum; Human ; Human subgingival plaque; Human saliva; Human urine; Human mucosa; Cattle ; Human stool	Metabolic reconstruction
Bacteria	Actinobacteria	79	Human feces; Human pleural fluid plaque; Human dental plaque; Human sputum; Human ; Human mucosa; Human supragingival plaque; Human subgingival plaque	Metabolic reconstruction
Bacteria	Verrucomicrobia	1	Human ; Human feces	Metabolic reconstruction
Bacteria	Bacteroidetes	126	Human feces; Human appendix biopsy; Human ; Human stool; Human saliva; Human gastric fluid; Human urine; Human subgingival plaque; Human supragingival plaque	Metabolic reconstruction
Bacteria	Synergistetes	3	Human feces	Metabolic reconstruction
Bacteria	Spirochaetes	1	Human feces	Metabolic reconstruction
Bacteria	Fusobacteria	12	Human feces; Human	Metabolic reconstruction
Archaea	Euryarchaeota	5		Metabolic reconstruction
Bacteria	Candidatus melainabacteria	1	Human feces	Metabolic reconstruction
Bacteria	Planctomycetes	1	Human feces	Metabolic reconstruction
Archaea	Crenarchaeota	1		Metabolic reconstruction
Bacteria	Thermodesulfobacteria	1
Archaea/Archaea	Euryarchaeota	1		Metabolic reconstruction
Eukaryota/Fungi	Ascomycota	1	Human feces; Human saliva	Unknown

Exposure Sources

Source Type	Species	Data Source	Reference
Animal	Chondrus crispus	FooDB	Manually Annotated
Animal	Laminaria	FooDB	Manually Annotated
Animal	Haliotis	FooDB	Manually Annotated
Animal	Strombidae	FooDB	Manually Annotated
Animal	Clupea harengus harengus	FooDB	Manually Annotated
Animal	Undaria pinnatifida	FooDB	Manually Annotated
Animal	Peprilus triacanthus	FooDB	Manually Annotated
Animal	Rhodophyta	FooDB	Manually Annotated
Animal	Myoxocephalus	FooDB	Manually Annotated
Animal	Eucheuma	FooDB	Manually Annotated
Animal	Saccharina japonica	FooDB	Manually Annotated
Animal	Spirulina	FooDB	Manually Annotated
Animal	Lota lota	FooDB	Manually Annotated
Animal	Porphyra umbilicalis	FooDB	Manually Annotated
Plant	Opuntia cochenillifera	FooDB	Manually Annotated
Plant	Vaccinium ovatum	FooDB	Manually Annotated
Plant	Cocos nucifera	FooDB	Manually Annotated
Plant	Phaseolus coccineus	FooDB	Manually Annotated
Plant	Thymus pulegioides	FooDB	Manually Annotated
Plant	Tamarindus indica	FooDB	Manually Annotated
Plant	Mespilus germanica	FooDB	Manually Annotated
Plant	Brassica rapa var. perviridis	FooDB	Manually Annotated
Plant	Cucurbita pepo var. cylindrica	FooDB	Manually Annotated
Plant	Mentha aquatica	FooDB	Manually Annotated
Plant	Salvia elegans	FooDB	Manually Annotated
Plant	Mentha	FooDB	Manually Annotated
Plant	Sagittaria latifolia	FooDB	Manually Annotated
Plant	Solanum tuberosum	FooDB	Manually Annotated
Plant	Olea europaea	FooDB	Manually Annotated
Plant	Sambucus	FooDB	Manually Annotated
Plant	Pinus	FooDB	Manually Annotated
Plant	Psidium guajava	FooDB	Manually Annotated
Plant	Syzygium cumini	FooDB	Manually Annotated
Plant	Tilia tomentosa	FooDB	Manually Annotated
Plant	Typha angustifolia	FooDB	Manually Annotated
Plant	Daucus carota	FooDB	Manually Annotated
Plant	Empetrum nigrum	FooDB	Manually Annotated
Plant	Valerianella locusta	FooDB	Manually Annotated
Plant	Myrica rubra	FooDB	Manually Annotated
Plant	Vaccinium vitis-idaea	FooDB	Manually Annotated
Plant	Vaccinium angustifolium x vaccinium corymbosum	FooDB	Manually Annotated
Plant	Sisymbrium	FooDB	Manually Annotated
Plant	Vanilla	FooDB	Manually Annotated
Plant	Carya	FooDB	Manually Annotated
Plant	Brassica oleracea l. var. capitata l. f. alba dc.	FooDB	Manually Annotated
Plant	Physalis philadelphica var. immaculata	FooDB	Manually Annotated
Plant	Vigna radiata	FooDB	Manually Annotated
Plant	Borago officinalis	FooDB	Manually Annotated
Plant	Raphanus sativus	FooDB	Manually Annotated
Plant	Prunus dulcis	FooDB	Manually Annotated
Plant	Hyssopus officinalis	FooDB	Manually Annotated
Plant	Manihot esculenta	FooDB	Manually Annotated
Plant	Beta vulgaris ssp. cicla	FooDB	Manually Annotated
Plant	Scorzonera hispanica	FooDB	Manually Annotated
Plant	Vigna unguiculata ssp. sesquipedalis	FooDB	Manually Annotated
Plant	Angelica keiskei	FooDB	Manually Annotated
Plant	Ipomoea aquatica	FooDB	Manually Annotated
Plant	Musa x paradisiaca	FooDB	Manually Annotated
Plant	Cuminum cyminum	FooDB	Manually Annotated
Plant	Rubus spectabilis	FooDB	Manually Annotated
Plant	Allium sativum	FooDB	Manually Annotated
Plant	Arachis hypogaea	FooDB	Manually Annotated
Plant	Rubus idaeus	FooDB	Manually Annotated
Plant	Cantharellus cibarius	FooDB	Manually Annotated
Plant	Sinapis alba	FooDB	Manually Annotated
Plant	Fragaria x ananassa	FooDB	Manually Annotated
Plant	Pyrus communis	FooDB	Manually Annotated
Plant	Brassica ruvo	FooDB	Manually Annotated
Plant	Apium graveolens var. secalinum	FooDB	Manually Annotated
Plant	Morus nigra	FooDB	Manually Annotated
Plant	Solanum lycopersicum	FooDB	Manually Annotated
Plant	Abelmoschus esculentus	FooDB	Manually Annotated
Plant	Moringa oleifera	FooDB	Manually Annotated
Plant	Pinus edulis	FooDB	Manually Annotated
Plant	Passiflora edulis	FooDB	Manually Annotated
Plant	Opuntia macrorhiza	FooDB	Manually Annotated
Plant	Vigna angularis	FooDB	Manually Annotated
Plant	Manilkara zapota	FooDB	Manually Annotated
Plant	Cucurbita pepo var. clypeata	FooDB	Manually Annotated
Plant	Helianthus annuus	FooDB	Manually Annotated
Plant	Mentha spicata	FooDB	Manually Annotated
Plant	Corylus	FooDB	Manually Annotated
Plant	Malus	FooDB	Manually Annotated
Plant	Pisum sativum	FooDB	Manually Annotated
Plant	Sambucus nigra	FooDB	Manually Annotated
Plant	Allium cepa	FooDB	Manually Annotated
Plant	Juglans	FooDB	Manually Annotated
Plant	Mangifera indica	FooDB	Manually Annotated
Plant	Petroselinum crispum	FooDB	Manually Annotated
Plant	Ribes nigrum	FooDB	Manually Annotated
Plant	Zingiber officinale	FooDB	Manually Annotated
Plant	Chamaemelum nobile	FooDB	Manually Annotated
Plant	Illicium verum	FooDB	Manually Annotated
Plant		FooDB	Manually Annotated
Plant	Laurus nobilis	FooDB	Manually Annotated
Plant	Auricularia auricula-judae	FooDB	Manually Annotated
Plant	Attalea speciosa	FooDB	Manually Annotated
Plant	Juglans ailanthifolia	FooDB	Manually Annotated
Plant	Melissa officinalis	FooDB	Manually Annotated
Plant	Hippophae rhamnoides	FooDB	Manually Annotated
Plant	Polygonum alpinum	FooDB	Manually Annotated
Plant	Brassica juncea	FooDB	Manually Annotated
Plant	Pediomelum esculentum	FooDB	Manually Annotated
Plant	Spinacia oleracea	FooDB	Manually Annotated
Plant	Auricularia polytricha	FooDB	Manually Annotated
Plant	Camellia oleifera	FooDB	Manually Annotated
Plant	Vaccinium corymbosum	FooDB	Manually Annotated
Plant	Chrysanthemum coronarium	FooDB	Manually Annotated
Plant	Eleocharis dulcis	FooDB	Manually Annotated
Plant	Thymus vulgaris	FooDB	Manually Annotated
Plant	Actinidia chinensis	FooDB	Manually Annotated
Plant	Carica papaya	FooDB	Manually Annotated
Plant	Pimenta dioica	FooDB	Manually Annotated
Plant	Medicago sativa	FooDB	Manually Annotated
Plant	Vigna mungo	FooDB	Manually Annotated
Plant	Rubus arcticus	FooDB	Manually Annotated
Plant	Agaricus bisporus	FooDB	Manually Annotated
Plant	Cajanus cajan	FooDB	Manually Annotated
Plant	Rumex articus	FooDB	Manually Annotated
Plant	Origanum majorana	FooDB	Manually Annotated
Plant	Armoracia rusticana	FooDB	Manually Annotated
Plant	Hibiscus sabdariffa	FooDB	Manually Annotated
Plant	Benincasa hispida	FooDB	Manually Annotated
Plant	Prunus persica	FooDB	Manually Annotated
Plant	Canarium ovatum	FooDB	Manually Annotated
Plant	Ribes aureum var. villosum	FooDB	Manually Annotated
Plant	Cucurbita pepo var. cylindrica	FooDB	Manually Annotated
Plant	Brassica oleracea var. gemmifera	FooDB	Manually Annotated
Plant	Foeniculum vulgare	FooDB	Manually Annotated
Plant	Phoenix dactylifera	FooDB	Manually Annotated
Plant	Vaccinium macrocarpon	FooDB	Manually Annotated
Plant		FooDB	Manually Annotated
Plant	Arctium lappa	FooDB	Manually Annotated
Plant	Brassica oleracea var. gongylodes	FooDB	Manually Annotated
Plant	Juglans cinerea	FooDB	Manually Annotated
Plant	Prunus cerasus	FooDB	Manually Annotated
Plant	Eruca vesicaria ssp. sativa	FooDB	Manually Annotated
Plant	Rosmarinus officinalis	FooDB	Manually Annotated
Plant	Artocarpus altilis	FooDB	Manually Annotated
Plant	Citrus x paradisi	FooDB	Manually Annotated
Plant	Vigna unguiculata	FooDB	Manually Annotated
Plant	Cynara scolymus	FooDB	Manually Annotated
Plant	Cyathea	FooDB	Manually Annotated
Plant	Metroxylon sagu	FooDB	Manually Annotated
Plant	Vitis rotundifolia	FooDB	Manually Annotated
Plant	Brosimum alicastrum	FooDB	Manually Annotated
Plant	Ficus carica	FooDB	Manually Annotated
Plant	Lentinus edodes	FooDB	Manually Annotated
Plant	Psidium cattleianum	FooDB	Manually Annotated
Plant	Beta vulgaris var. rubra	FooDB	Manually Annotated
Plant	Castanea mollissima	FooDB	Manually Annotated
Plant	Lepidium sativum	FooDB	Manually Annotated
Plant	Morus	FooDB	Manually Annotated
Plant	Helianthus tuberosus	FooDB	Manually Annotated
Plant	Phytolacca americana	FooDB	Manually Annotated
Plant	Grifola frondosa	FooDB	Manually Annotated
Plant	Vitis labrusca	FooDB	Manually Annotated
Plant	Tetragonia tetragonioides	FooDB	Manually Annotated
Plant	Artemisia vulgaris	FooDB	Manually Annotated
Plant	Cucumis metuliferus	FooDB	Manually Annotated
Plant	Nephelium lappaceum	FooDB	Manually Annotated
Plant	Myrica	FooDB	Manually Annotated
Plant		FooDB	Manually Annotated
Plant	Corylus avellana	FooDB	Manually Annotated
Plant	Castanea crenata	FooDB	Manually Annotated
Plant	Litchi chinensis	FooDB	Manually Annotated
Plant	Juglans regia	FooDB	Manually Annotated
Plant	Quercus	FooDB	Manually Annotated
Plant	Trigonella foenum-graecum	FooDB	Manually Annotated
Plant	Vaccinium angustifolium	FooDB	Manually Annotated
Plant	Malpighia emarginata	FooDB	Manually Annotated
Plant	Physalis	FooDB	Manually Annotated
Plant	Brassica oleracea var. sabauda	FooDB	Manually Annotated
Plant	Thelesperma	FooDB	Manually Annotated
Plant	Brassica napus	FooDB	Manually Annotated
Plant	Asparagus officinalis	FooDB	Manually Annotated
Plant	Chamerion angustifolium	FooDB	Manually Annotated
Plant	Levisticum officinale	FooDB	Manually Annotated
Plant	Pimpinella anisum	FooDB	Manually Annotated
Plant	Vaccinium elliottii	FooDB	Manually Annotated
Plant	Artemisia dracunculus	FooDB	Manually Annotated
Plant	Matricaria recutita	FooDB	Manually Annotated
Plant	Citrus aurantiifolia	FooDB	Manually Annotated
Plant	Ziziphus zizyphus	FooDB	Manually Annotated
Plant	Lactuca sativa	FooDB	Manually Annotated
Plant	Dimocarpus longan	FooDB	Manually Annotated
Plant	Eragrostis tef	FooDB	Manually Annotated
Plant	Salvia hispanica	FooDB	Manually Annotated
Plant	Pistacia vera	FooDB	Manually Annotated
Plant	Cynara cardunculus	FooDB	Manually Annotated
Plant	Vitellaria paradoxa	FooDB	Manually Annotated
Plant	Pangium edule	FooDB	Manually Annotated
Plant	Malus pumila	FooDB	Manually Annotated
Plant	Allium	FooDB	Manually Annotated
Plant	Brassica oleracea var. viridis	FooDB	Manually Annotated
Plant	Punica granatum	FooDB	Manually Annotated
Plant	Agave	FooDB	Manually Annotated
Plant	Hedysarum alpinum	FooDB	Manually Annotated
Plant	Diospyros	FooDB	Manually Annotated
Plant		FooDB	Manually Annotated
Plant	Vigna aconitifolia	FooDB	Manually Annotated
Plant	Amaranthus	FooDB	Manually Annotated
Plant	Gossypium	FooDB	Manually Annotated
Plant	Beta vulgaris	FooDB	Manually Annotated
Plant	Mammea americana	FooDB	Manually Annotated
Plant	Brassica alboglabra	FooDB	Manually Annotated
Plant	Annona squamosa	FooDB	Manually Annotated
Plant	Apium graveolens var. dulce	FooDB	Manually Annotated
Plant	Vitis	FooDB	Manually Annotated
Plant	Xanthosoma sagittifolium	FooDB	Manually Annotated
Plant	Basella alba	FooDB	Manually Annotated
Plant	Cucumis sativus	FooDB	Manually Annotated
Plant	Citrus latifolia	FooDB	Manually Annotated
Plant	Carya illinoinensis	FooDB	Manually Annotated
Plant	Capsicum baccatum var. baccatum	FooDB	Manually Annotated
Plant	Byrsonima crassifolia	FooDB	Manually Annotated
Plant	Capsicum pubescens	FooDB	Manually Annotated
Plant	Cinnamomum aromaticum	FooDB	Manually Annotated
Plant	Ribes rubrum	FooDB	Manually Annotated
Plant	Crateva religiosa	FooDB	Manually Annotated
Plant		FooDB	Manually Annotated
Plant	Vitis aestivalis	FooDB	Manually Annotated
Plant	Brassica rapa var. chinensis	FooDB	Manually Annotated
Plant	Eugenia javanica	FooDB	Manually Annotated
Plant	Portulaca oleracea	FooDB	Manually Annotated
Plant	Ipomoea batatas	FooDB	Manually Annotated
Plant	Mentha arvensis	FooDB	Manually Annotated
Plant	Pastinaca sativa	FooDB	Manually Annotated
Plant	Cucurbita maxima	FooDB	Manually Annotated
Plant	Vaccinium stamineum	FooDB	Manually Annotated
Plant	Solanum lycopersicum var. cerasiforme	FooDB	Manually Annotated
Plant	Chenopodium album	FooDB	Manually Annotated
Plant	Psophocarpus tetragonolobus	FooDB	Manually Annotated
Plant	Allium ampeloprasum	FooDB	Manually Annotated
Plant	Brassica oleracea	FooDB	Manually Annotated
Plant	Sechium edule	FooDB	Manually Annotated
Plant	Lactuca sativa l. var. longifolia	FooDB	Manually Annotated
Plant	Grataegosorbus mitschurinii	FooDB	Manually Annotated
Plant	Diospyros virginiana	FooDB	Manually Annotated
Plant	Origanum x majoricum	FooDB	Manually Annotated
Plant	Rubus x loganobaccus	FooDB	Manually Annotated
Plant	Tragopogon porrifolius	FooDB	Manually Annotated
Plant	Taraxacum officinale	FooDB	Manually Annotated
Plant	Rumex	FooDB	Manually Annotated
Plant	Allium ascalonicum	FooDB	Manually Annotated
Plant	Curcuma longa	FooDB	Manually Annotated
Plant	Rubus chamaemorus	FooDB	Manually Annotated
Plant	Elettaria cardamomum	FooDB	Manually Annotated
Plant	Citrullus lanatus var. fistulosus	FooDB	Manually Annotated
Plant	Ananas comosus	FooDB	Manually Annotated
Plant	Persea americana	FooDB	Manually Annotated
Plant	Amelanchier alnifolia	FooDB	Manually Annotated
Plant	Eugenia uniflora	FooDB	Manually Annotated
Plant	Annona reticulata	FooDB	Manually Annotated
Plant	Cichorium intybus	FooDB	Manually Annotated
Plant	Sesbania bispinosa	FooDB	Manually Annotated
Plant	Chenopodium quinoa	FooDB	Manually Annotated
Plant	Brassica oleracea var. botrytis	FooDB	Manually Annotated
Plant	Ribes x nidigrolaria	FooDB	Manually Annotated
Plant	Garcinia mangostana	FooDB	Manually Annotated
Plant	Cucumis melo	FooDB	Manually Annotated
Plant	Dioscorea pentaphylla	FooDB	Manually Annotated
Plant	Corchorus olitorius	FooDB	Manually Annotated
Plant	Juglans nigra	FooDB	Manually Annotated
Plant	Lathyrus sativus	FooDB	Manually Annotated
Plant	Allium tuberosum	FooDB	Manually Annotated
Plant	Cinnamomum verum	FooDB	Manually Annotated
Plant	Glycine max	FooDB	Manually Annotated
Plant	Gaylussacia baccata	FooDB	Manually Annotated
Plant	Petasites japonicus	FooDB	Manually Annotated
Plant	Prunus tomentosa	FooDB	Manually Annotated
Plant	Ocimum basilicum	FooDB	Manually Annotated
Plant	Mentha x piperita	FooDB	Manually Annotated
Plant	Maranta arundinacea	FooDB	Manually Annotated
Plant	Matteuccia struthiopteris	FooDB	Manually Annotated
Plant	Cucurbita moschata	FooDB	Manually Annotated
Plant	Macadamia	FooDB	Manually Annotated
Plant	Tilia	FooDB	Manually Annotated
Plant	Citrus limon	FooDB	Manually Annotated
Plant	Vaccinium myrtilloides	FooDB	Manually Annotated
Plant	Capsicum annuum var. annuum	FooDB	Manually Annotated
Plant	Apium graveolens var. rapaceum	FooDB	Manually Annotated
Plant	Papaver	FooDB	Manually Annotated
Plant	Rosa	FooDB	Manually Annotated
Plant	Nelumbo	FooDB	Manually Annotated
Plant	Brassica oleracea var. conica	FooDB	Manually Annotated
Plant	Sesamum orientale	FooDB	Manually Annotated
Plant	Annona cherimola	FooDB	Manually Annotated
Plant	Brassica rapa var. pekinensis	FooDB	Manually Annotated
Plant	Brassica rapa	FooDB	Manually Annotated
Plant	Lippia graveolens	FooDB	Manually Annotated
Plant	Prunus	FooDB	Manually Annotated
Plant	Capparis spinosa	FooDB	Manually Annotated
Plant	Citrus sinensis	FooDB	Manually Annotated
Plant	Lens culinaris	FooDB	Manually Annotated
Plant	Vaccinium deliciosum	FooDB	Manually Annotated
Plant	Phaseolus lunatus	FooDB	Manually Annotated
Plant	Artocarpus heterophyllus	FooDB	Manually Annotated
Plant	Prunus virginiana	FooDB	Manually Annotated
Plant	Musa acuminata	FooDB	Manually Annotated
Plant	Citrullus lanatus	FooDB	Manually Annotated
Plant	Linum usitatissimum	FooDB	Manually Annotated
Plant	Vigna unguiculata ssp. unguiculata	FooDB	Manually Annotated
Plant	Macadamia tetraphylla	FooDB	Manually Annotated
Plant	Phyllostachys edulis	FooDB	Manually Annotated
Plant	Lagenaria siceraria	FooDB	Manually Annotated
Plant	Prunus domestica	FooDB	Manually Annotated
Plant	Prunus armeniaca	FooDB	Manually Annotated
Plant	Carum carvi	FooDB	Manually Annotated
Plant	Allium schoenoprasum	FooDB	Manually Annotated
Plant	Carissa macrocarpa	FooDB	Manually Annotated
Plant	Citrus reticulata	FooDB	Manually Annotated
Plant	Satureja hortensis	FooDB	Manually Annotated
Plant	Averrhoa carambola	FooDB	Manually Annotated
Plant	Brassica rapa var. rapa	FooDB	Manually Annotated
Plant	Sorbus aucuparia	FooDB	Manually Annotated
Plant	Anethum graveolens	FooDB	Manually Annotated
Plant	Nelumbo nucifera	FooDB	Manually Annotated
Plant	Coriandrum sativum	FooDB	Manually Annotated
Plant	Bertholletia excelsa	FooDB	Manually Annotated
Plant	Brassica oleracea var. costata	FooDB	Manually Annotated
Plant	Panax	FooDB	Manually Annotated
Plant	Ceratonia siliqua	FooDB	Manually Annotated
Plant	Cymbopogon citratus	FooDB	Manually Annotated
Plant	Luffa aegyptiaca	FooDB	Manually Annotated
Plant	Anacardium occidentale	FooDB	Manually Annotated
Plant	Carthamus tinctorius	FooDB	Manually Annotated
Plant	Rubus occidentalis	FooDB	Manually Annotated
Plant	Vigna umbellata	FooDB	Manually Annotated
Plant	Cicer arietinum	FooDB	Manually Annotated
Plant	Allium fistulosum	FooDB	Manually Annotated
Plant	Capsicum	FooDB	Manually Annotated
Plant	Vaccinium alaskaense	FooDB	Manually Annotated
Plant	Lupinus	FooDB	Manually Annotated
Plant	Tilia cordata	FooDB	Manually Annotated
Plant	Camellia sinensis	FooDB	Manually Annotated
Plant	Prunus persica var. nucipersica	FooDB	Manually Annotated
Plant	Durio zibethinus	FooDB	Manually Annotated
Plant	Eriobotrya japonica	FooDB	Manually Annotated
Plant	Solanum lycopersicum var. lycopersicum	FooDB	Manually Annotated
Plant	Brassica napus var. pabularia	FooDB	Manually Annotated
Plant	Oenothera biennis	FooDB	Manually Annotated
Plant	Diospyros kaki	FooDB	Manually Annotated
Plant	Ribes glandulosum	FooDB	Manually Annotated
Plant	Phaseolus vulgaris	FooDB	Manually Annotated
Plant	Theobroma cacao	FooDB	Manually Annotated
Plant	Virola surinamensis	FooDB	Manually Annotated
Plant	Verbena officinalis	FooDB	Manually Annotated
Plant	Daucus carota ssp. sativus	FooDB	Manually Annotated
Plant	Vaccinium oxycoccos	FooDB	Manually Annotated
Plant	Rumex acetosa	FooDB	Manually Annotated
Plant	Syzygium aromaticum	FooDB	Manually Annotated
Plant	Pyrus pyrifolia	FooDB	Manually Annotated
Plant	Vaccinium myrtillus	FooDB	Manually Annotated
Plant	Vaccinium parvifolium	FooDB	Manually Annotated
Plant	Aloysia triphylla	FooDB	Manually Annotated
Plant	Brassica oleracea var. capitata	FooDB	Manually Annotated
Plant	Capsicum chinense	FooDB	Manually Annotated
Plant	Vicia faba	FooDB	Manually Annotated
Plant	Vaccinium reticulatum	FooDB	Manually Annotated
Plant	Solanum quitoense	FooDB	Manually Annotated
Plant	Ginkgo biloba	FooDB	Manually Annotated
Plant	Theobroma grandiflorum	FooDB	Manually Annotated
Plant	Vigna unguiculata ssp. cylindrica	FooDB	Manually Annotated
Plant	Flammulina velutipes	FooDB	Manually Annotated
Plant	Satureja montana	FooDB	Manually Annotated
Plant		FooDB	Manually Annotated
Plant	Vitis vinifera	FooDB	Manually Annotated
Plant	Citrus japonica	FooDB	Manually Annotated
Plant	Prunus avium	FooDB	Manually Annotated
Plant	Perideridia oregana	FooDB	Manually Annotated
Plant	Vaccinium arboreum	FooDB	Manually Annotated
Plant	Pouteria sapota	FooDB	Manually Annotated
Plant	Wasabia japonica	FooDB	Manually Annotated
Plant	Piper nigrum	FooDB	Manually Annotated
Plant	Origanum onites	FooDB	Manually Annotated
Plant	Capsicum annuum	FooDB	Manually Annotated
Plant	Origanum vulgare	FooDB	Manually Annotated
Plant	Viburnum edule	FooDB	Manually Annotated
Plant	Dioscorea	FooDB	Manually Annotated
Plant	Brassica oleracea var. italica	FooDB	Manually Annotated
Plant	Momordica charantia	FooDB	Manually Annotated
Plant	Vaccinium uliginosum	FooDB	Manually Annotated
Plant	Castanea	FooDB	Manually Annotated
Plant	Rubus ursinus x idaeus	FooDB	Manually Annotated
Plant	Pleurotus ostreatus	FooDB	Manually Annotated
Plant	Cirsium	FooDB	Manually Annotated
Plant	Solanum melongena	FooDB	Manually Annotated
Plant	Opuntia	FooDB	Manually Annotated
Plant	Raphanus sativus var. sativus	FooDB	Manually Annotated
Plant	Colocasia esculenta	FooDB	Manually Annotated
Plant	Prunus persica var. persica	FooDB	Manually Annotated
Plant	Anthriscus cerefolium	FooDB	Manually Annotated
Plant	Nuphar lutea	FooDB	Manually Annotated
Plant	Lupinus albus	FooDB	Manually Annotated
Plant	Myristica fragrans	FooDB	Manually Annotated
Plant	Pachyrhizus erosus	FooDB	Manually Annotated
Plant	Cichorium endivia	FooDB	Manually Annotated
Plant	Apium graveolens	FooDB	Manually Annotated
Plant	Elaeis	FooDB	Manually Annotated
Plant	Cinnamomum	FooDB	Manually Annotated
Plant	Ribes uva-crispa	FooDB	Manually Annotated
Plant	Feijoa sellowiana	FooDB	Manually Annotated
Plant	Dysphania ambrosioides	FooDB	Manually Annotated
Plant	Raphanus sativus var. niger	FooDB	Manually Annotated
Plant	Photinia melanocarpa	FooDB	Manually Annotated
Plant	Salvia officinalis	FooDB	Manually Annotated
Plant	Rheum rhabarbarum	FooDB	Manually Annotated
Plant	Vaccinium	FooDB	Manually Annotated
Plant	Lablab purpureus	FooDB	Manually Annotated
Plant	Crocus sativus	FooDB	Manually Annotated
Plant	Citrus maxima	FooDB	Manually Annotated
Plant	Syzygium jambos	FooDB	Manually Annotated
Plant	Salix pulchra	FooDB	Manually Annotated
Plant	Castanea sativa	FooDB	Manually Annotated
Plant	Cydonia oblonga	FooDB	Manually Annotated
Plant	Annona muricata	FooDB	Manually Annotated
Plant	Fagus	FooDB	Manually Annotated
Plant	Cucurbita	FooDB	Manually Annotated

Source Type	Activity	Data Source	Reference
Drugs	Antimicrobial	U.S. Environmental Protection Agency	CompTox
Cosmetics	Not Available	U.S. Environmental Protection Agency	CompTox
Domestics	Not Available	U.S. Environmental Protection Agency	CompTox

Host Biospecimen and Location

Host and Biospecimen	Status	Age	Sex	Health Condition	Data Source	Reference
Human Feces	Detected but not Quantified				HMDB
Human Liver	Detected but not Quantified	Not Specified	Not Specified	Normal	HMDB	34986597
Human Placenta	Detected but not Quantified	Not Specified	Not Specified	Normal	HMDB	34986597

External Links

HMDB ID

HMDB0000935

DrugBank ID

DB03041

Phenol Explorer Compound ID

Not Available

FooDB ID

KNApSAcK ID

Chemspider ID

KEGG Compound ID

BioCyc ID

BiGG ID

Wikipedia Link

Uridine_diphosphate_glucuronic_acid

METLIN ID

5884

PubChem Compound

17473

PDB ID

Not Available

ChEBI ID

17200

Food Biomarker Ontology

Not Available

References

Synthesis Reference

Not Available

General References

Cappiello M, Giuliani L, Pacifici GM: Distribution of UDP-glucuronosyltransferase and its endogenous substrate uridine 5'-diphosphoglucuronic acid in human tissues. Eur J Clin Pharmacol. 1991;41(4):345-50. doi: 10.1007/BF00314965. [PubMed:1804651 ]
Huskey SW, Doss GA, Miller RR, Schoen WR, Chiu SH: N-glucuronidation reactions. II. Relative N-glucuronidation reactivity of methylbiphenyl tetrazole, methylbiphenyl triazole, and methylbiphenyl imidazole in rat, monkey, and human hepatic microsomes. Drug Metab Dispos. 1994 Jul-Aug;22(4):651-8. [PubMed:7956743 ]
Hagenauer B, Salamon A, Thalhammer T, Kunert O, Haslinger E, Klingler P, Senderowicz AM, Sausville EA, Jager W: In vitro glucuronidation of the cyclin-dependent kinase inhibitor flavopiridol by rat and human liver microsomes: involvement of UDP-glucuronosyltransferases 1A1 and 1A9. Drug Metab Dispos. 2001 Apr;29(4 Pt 1):407-14. [PubMed:11259324 ]
Alkharfy KM, Frye RF: High-performance liquid chromatographic assay for acetaminophen glucuronide in human liver microsomes. J Chromatogr B Biomed Sci Appl. 2001 Apr 5;753(2):303-8. doi: 10.1016/s0378-4347(00)00566-1. [PubMed:11334344 ]
Cappiello M, Giuliani L, Rane A, Pacifici GM: Uridine 5'-diphosphoglucuronic acid (UDPGLcUA) in the human fetal liver, kidney and placenta. Eur J Drug Metab Pharmacokinet. 2000 Jul-Dec;25(3-4):161-3. doi: 10.1007/BF03192308. [PubMed:11420884 ]
Ghosal A, Hapangama N, Yuan Y, Achanfuo-Yeboah J, Iannucci R, Chowdhury S, Alton K, Patrick JE, Zbaida S: Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of ezetimibe (Zetia). Drug Metab Dispos. 2004 Mar;32(3):314-20. doi: 10.1124/dmd.32.3.314. [PubMed:14977865 ]
Quintus J, Kovar KA, Link P, Hamacher H: Urinary excretion of arbutin metabolites after oral administration of bearberry leaf extracts. Planta Med. 2005 Feb;71(2):147-52. doi: 10.1055/s-2005-837782. [PubMed:15729623 ]
Fondeur-Gelinotte M, Lattard V, Oriol R, Mollicone R, Jacquinet JC, Mulliert G, Gulberti S, Netter P, Magdalou J, Ouzzine M, Fournel-Gigleux S: Phylogenetic and mutational analyses reveal key residues for UDP-glucuronic acid binding and activity of beta1,3-glucuronosyltransferase I (GlcAT-I). Protein Sci. 2006 Jul;15(7):1667-78. doi: 10.1110/ps.062089106. [PubMed:16815917 ]
Elshenawy S, Pinney SE, Stuart T, Doulias PT, Zura G, Parry S, Elovitz MA, Bennett MJ, Bansal A, Strauss JF 3rd, Ischiropoulos H, Simmons RA: The Metabolomic Signature of the Placenta in Spontaneous Preterm Birth. Int J Mol Sci. 2020 Feb 4;21(3). pii: ijms21031043. doi: 10.3390/ijms21031043. [PubMed:32033212 ]
Norbert W. Tietz (1990). Clinical Guide to Laboratory Tests, 2nd Ed. Norbert W. Tietz 1990. W B Saunders Co.

Showing metabocard for UDP-Glucuronic acid (MMDBc0029638)

MOL for #<Metabolite:0x00007fdb4c7da6e8>

3D MOL for #<Metabolite:0x00007fdb4c7da6e8>

3D SDF for #<Metabolite:0x00007fdb4c7da6e8>

3D-SDF for #<Metabolite:0x00007fdb4c7da6e8>

PDB for #<Metabolite:0x00007fdb4c7da6e8>

3D PDB for #<Metabolite:0x00007fdb4c7da6e8>

SMILES for #<Metabolite:0x00007fdb4c7da6e8>

INCHI for #<Metabolite:0x00007fdb4c7da6e8>

Structure for #<Metabolite:0x00007fdb4c7da6e8>

3D Structure for #<Metabolite:0x00007fdb4c7da6e8>