MiMeDB: Showing metabocard for Thiamine monophosphate (MMDBc0029696)

Record Information

Version

1.0

Status

Detected and Quantified

Creation Date

2021-11-17 23:37:56 UTC

Update Date

2024-04-30 19:40:49 UTC

Metabolite ID

MMDBc0029696

Metabolite Identification

Common Name

Thiamine monophosphate

Description

Thiamine dihydrogen phosphate ester. The monophosphate ester of thiamine. Synonyms: monophosphothiamine; vitamin B1 monophosphate. -- Pubchem

Structure

MOL SDF PDB SMILES InChI


  Mrv1652304282021232D          

 22 23  0  0  0  0            999 V2000
10001.364010000.3662    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
 9999.999710001.2799    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
10001.3640 9998.7200    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
 9998.607310000.3662    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
 9997.8929 9999.9530    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
10004.2141 9998.7200    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
 9997.180710000.3662    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
 9996.4682 9999.9530    0.0000 P   0  0  0  0  0  0  0  0  0  0  0  0
 9996.8804 9999.2406    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
 9995.755810000.3662    0.0000 O   0  5  0  0  0  0  0  0  0  0  0  0
 9996.0579 9999.2406    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
 9999.982110000.4478    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
 9999.3147 9999.9628    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
 9999.5696 9999.1782    0.0000 S   0  0  0  0  0  0  0  0  0  0  0  0
10000.3946 9999.1782    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
10000.6495 9999.9628    0.0000 N   0  3  0  0  0  0  0  0  0  0  0  0
10002.790110000.3672    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
10002.0756 9999.9547    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
10002.0756 9999.1296    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
10002.7901 9998.7172    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
10003.5046 9999.1296    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
10003.5046 9999.9547    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
  4  5  1  0  0  0  0
  5  7  1  0  0  0  0
  7  8  1  0  0  0  0
  8  9  2  0  0  0  0
  8 10  1  0  0  0  0
  8 11  1  0  0  0  0
 12 13  2  0  0  0  0
 13 14  1  0  0  0  0
 14 15  1  0  0  0  0
 12 16  1  0  0  0  0
 15 16  2  0  0  0  0
  1 16  1  0  0  0  0
 12  2  1  0  0  0  0
 13  4  1  0  0  0  0
 17 18  2  0  0  0  0
 18 19  1  0  0  0  0
 19 20  2  0  0  0  0
 20 21  1  0  0  0  0
 17 22  1  0  0  0  0
 21 22  2  0  0  0  0
  1 18  1  0  0  0  0
 19  3  1  0  0  0  0
 21  6  1  0  0  0  0
M  CHG  2  10  -1  16   1
M  END
> <DATABASE_ID>
MMDBc0029696

> <DATABASE_NAME>
MIME

> <SMILES>
CC1=C(CCOP(O)([O-])=O)SC=[N+]1CC1=CN=C(C)N=C1N

> <INCHI_IDENTIFIER>
InChI=1S/C12H17N4O4PS/c1-8-11(3-4-20-21(17,18)19)22-7-16(8)6-10-5-14-9(2)15-12(10)13/h5,7H,3-4,6H2,1-2H3,(H3-,13,14,15,17,18,19)

> <INCHI_KEY>
HZSAJDVWZRBGIF-UHFFFAOYSA-N

> <FORMULA>
C12H17N4O4PS

> <MOLECULAR_WEIGHT>
344.327

> <EXACT_MASS>
344.070812254

> <JCHEM_ACCEPTOR_COUNT>
6

> <JCHEM_ATOM_COUNT>
39

> <JCHEM_AVERAGE_POLARIZABILITY>
31.956487685608256

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
2

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-[2-(hydrogen phosphonooxy)ethyl]-4-methyl-1,3-thiazol-3-ium

> <ALOGPS_LOGP>
-1.68

> <JCHEM_LOGP>
-5.696316403219863

> <ALOGPS_LOGS>
-3.65

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
2

> <JCHEM_PHYSIOLOGICAL_CHARGE>
-1

> <JCHEM_PKA>
6.712600648963036

> <JCHEM_PKA_STRONGEST_ACIDIC>
1.6589988406382288

> <JCHEM_PKA_STRONGEST_BASIC>
5.507552519532389

> <JCHEM_POLAR_SURFACE_AREA>
125.27000000000001

> <JCHEM_REFRACTIVITY>
83.15090000000001

> <JCHEM_ROTATABLE_BOND_COUNT>
6

> <JCHEM_RULE_OF_FIVE>
1

> <ALOGPS_SOLUBILITY>
8.90e-02 g/l

> <JCHEM_TRADITIONAL_IUPAC>
3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-[2-(hydrogen phosphonooxy)ethyl]-4-methyl-1,3-thiazol-3-ium

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 28-APR-20   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   28-APR-20         0                                  
HETATM    1  C   UNK     0    8669.2138667.350   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0    8666.6668669.056   0.000  0.00  0.00           C+0
HETATM    3  N   UNK     0    8669.2138664.277   0.000  0.00  0.00           N+0
HETATM    4  C   UNK     0    8664.0678667.350   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0    8662.7338666.579   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0    8674.5338664.277   0.000  0.00  0.00           C+0
HETATM    7  O   UNK     0    8661.4048667.350   0.000  0.00  0.00           O+0
HETATM    8  P   UNK     0    8660.0748666.579   0.000  0.00  0.00           P+0
HETATM    9  O   UNK     0    8660.8438665.249   0.000  0.00  0.00           O+0
HETATM   10  O   UNK     0    8658.7448667.350   0.000  0.00  0.00           O-1
HETATM   11  O   UNK     0    8659.3088665.249   0.000  0.00  0.00           O+0
HETATM   12  C   UNK     0    8666.6338667.503   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0    8665.3878666.597   0.000  0.00  0.00           C+0
HETATM   14  S   UNK     0    8665.8638665.133   0.000  0.00  0.00           S+0
HETATM   15  C   UNK     0    8667.4038665.133   0.000  0.00  0.00           C+0
HETATM   16  N   UNK     0    8667.8798666.597   0.000  0.00  0.00           N+1
HETATM   17  C   UNK     0    8671.8758667.352   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0    8670.5418666.582   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0    8670.5418665.042   0.000  0.00  0.00           C+0
HETATM   20  N   UNK     0    8671.8758664.272   0.000  0.00  0.00           N+0
HETATM   21  C   UNK     0    8673.2098665.042   0.000  0.00  0.00           C+0
HETATM   22  N   UNK     0    8673.2098666.582   0.000  0.00  0.00           N+0
CONECT    1   16   18                                                       
CONECT    2   12                                                            
CONECT    3   19                                                            
CONECT    4    5   13                                                       
CONECT    5    4    7                                                       
CONECT    6   21                                                            
CONECT    7    5    8                                                       
CONECT    8    7    9   10   11                                             
CONECT    9    8                                                            
CONECT   10    8                                                            
CONECT   11    8                                                            
CONECT   12   13   16    2                                                  
CONECT   13   12   14    4                                                  
CONECT   14   13   15                                                       
CONECT   15   14   16                                                       
CONECT   16   12   15    1                                                  
CONECT   17   18   22                                                       
CONECT   18   17   19    1                                                  
CONECT   19   18   20    3                                                  
CONECT   20   19   21                                                       
CONECT   21   20   22    6                                                  
CONECT   22   17   21                                                       
MASTER        0    0    0    0    0    0    0    0   22    0   46    0
END

Synonyms

Value	Source
THIAMIN phosphATE	ChEBI
THIAMIN phosphoric acid	Generator
Thiamine monophosphoric acid	Generator
Aneurin-monophosphorsaeureester	HMDB
Aneurine monophosphate	HMDB
Monofosfotiamina	HMDB
monoPhosphoric ester OF thiamine	HMDB
Monophosphothiamine	HMDB
Monophosphothiaminum	HMDB
Phosphothiaminum	HMDB
Thiamin dihydrogenphosphate	HMDB
Thiamin monophosphate	HMDB
Thiamine monophosphate dihydrate	HMDB
Thiamine phosphate	HMDB
Tiamina monofosfato	HMDB
TMP	HMDB
monoPhosphate, thiamine	HMDB
Phosphoester, thiamine	HMDB
Thiamine phosphoester	HMDB

Molecular Formula

C₁₂H₁₇N₄O₄PS

Average Mass

344.327

Monoisotopic Mass

344.070812254

IUPAC Name

3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-[2-(hydrogen phosphonooxy)ethyl]-4-methyl-1,3-thiazol-3-ium

Traditional Name

3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-[2-(hydrogen phosphonooxy)ethyl]-4-methyl-1,3-thiazol-3-ium

CAS Registry Number

495-23-8

SMILES

CC1=C(CCOP(O)([O-])=O)SC=[N+]1CC1=CN=C(C)N=C1N

InChI Identifier

InChI=1S/C12H17N4O4PS/c1-8-11(3-4-20-21(17,18)19)22-7-16(8)6-10-5-14-9(2)15-12(10)13/h5,7H,3-4,6H2,1-2H3,(H3-,13,14,15,17,18,19)

InChI Key

HZSAJDVWZRBGIF-UHFFFAOYSA-N

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as thiamine phosphates. These are thiamine derivatives in which the hydroxyl group of the ethanol moiety is substituted by a phosphate group.

Kingdom

Organic compounds

Super Class

Organoheterocyclic compounds

Class

Diazines

Sub Class

Pyrimidines and pyrimidine derivatives

Direct Parent

Thiamine phosphates

Alternative Parents

Substituents

Thiamine-phosphate
4,5-disubstituted 1,3-thiazole
Aminopyrimidine
Organic phosphoric acid derivative
Phosphoric acid ester
Alkyl phosphate
Imidolactam
Azole
Thiazole
Heteroaromatic compound
Azacycle
Amine
Hydrocarbon derivative
Primary amine
Organic oxide
Organooxygen compound
Organonitrogen compound
Organopnictogen compound
Organic nitrogen compound
Organic oxygen compound
Organic zwitterion
Aromatic heteromonocyclic compound

Molecular Framework

Aromatic heteromonocyclic compounds

External Descriptors

thiamine phosphate (CHEBI:37574 )

Functional Ontology

Not Available

Physical Properties

State

Solid

Predicted Properties

Property	Value	Source
Water Solubility	0.089 g/L	ALOGPS
logP	-1.7	ALOGPS
logP	-5.7	ChemAxon
logS	-3.6	ALOGPS
pKa (Strongest Acidic)	1.66	ChemAxon
pKa (Strongest Basic)	5.51	ChemAxon
Physiological Charge	-1	ChemAxon
Hydrogen Acceptor Count	6	ChemAxon
Hydrogen Donor Count	2	ChemAxon
Polar Surface Area	125.27 Å²	ChemAxon
Rotatable Bond Count	6	ChemAxon
Refractivity	83.15 m³·mol⁻¹	ChemAxon
Polarizability	31.96 Å³	ChemAxon
Number of Rings	2	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

Spectra

Spectrum Type	Description	Splash Key	Deposition Date	View
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive	splash10-0002-9231000000-81e5c080b3d74143f747	2016-09-22	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - , positive	splash10-00di-0910000000-91bfc26c8bd1479b1d71	2017-09-14	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 10V, Positive	splash10-0002-1109000000-5f9aae260ebb3a926a1e	2016-09-12	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 20V, Positive	splash10-0002-8149000000-ee028761e2cc2fbcf3a7	2016-09-12	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 40V, Positive	splash10-0a6s-2900000000-1aea69164d97d9b339bb	2016-09-12	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 10V, Negative	splash10-0006-2109000000-677b83e983efd6a9ef6d	2016-09-12	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 20V, Negative	splash10-001m-9001000000-3303a6492894e799e8b6	2016-09-12	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 40V, Negative	splash10-000t-9000000000-fc6ccde31ede591e6d54	2016-09-12	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 100 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 1000 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 200 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 300 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 400 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 500 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 600 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 700 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 800 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 900 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)		2022-08-20	View Spectrum

Biological Properties

Cellular Locations

Cytoplasm
Extracellular
Membrane
Mitochondria

Biospecimen Locations

Cerebrospinal Fluid (CSF)
Feces

Tissue Locations

Not Available

Associated OMIM IDs

114500 (Colorectal cancer)
610247 (Eosinophilic esophagitis)

Human Proteins and Enzymes

Protein ID	Protein Name	Protein Type	Uniprot ID	Species

Human Pathways

Pathways

Name	SMPDB/PathBank

Metabolic Reactions

Reaction ID	Precursor	Product	Enzyme	Reaction Type	Data Source	Reference
MMDBr0002205	Water	Hydrogen Ion	Not Available	Thiamin Pyrophosphatase	VMH; KEGG	30371894
MMDBr0002207	Water	Hydrogen Ion	Not Available	Thiamin Pyrophosphatase, Mitochondrial	VMH; KEGG	30371894
MMDBr0002232	Water	Water	Solute carrier family 19 (folate transporter), member 1	Thiamine Monophosphate Transport in via Anion Antiport	VMH	10542220 14770311
MMDBr0002233	Water	Water	Not Available	Thiamine Monophosphate Transport, Mitochondrial	VMH	12014993 9755848
MMDBr0002234	Water	Phosphate	Not Available	Thiamin Phosphatase	VMH; KEGG	30371894
MMDBr0006782	Thiamine monophosphate	Thiamine monophosphate	Not Available	Thiamine Monophosphate Transport (Passive - Red Blood Cell)	VMH	30371894
MMDBr0007583	2-Methyl-4-amino-5-hydroxymethylpyrimidine diphosphate	Pyrophosphate	Not Available	Thiamine-phosphate diphosphorylase	VMH	30371894
MMDBr0008424	Hydrogen Ion	Hydrogen Ion	Not Available	Thiamin monophosphate transport in via proton symport, irreversible	VMH	30371894
MMDBr0012619	Adenosine triphosphate	ADP	Not Available	thiamine kinase	VMH	30371894
MMDBr0012620	Adenosine triphosphate	ADP	Not Available	thiamine-phosphate kinase	VMH	30371894
MMDBr0018459	Hydrogen Ion	Carbon dioxide	Thiamine-phosphate synthase	Synthesis	PathBank	31602464
MMDBr0018460	Adenosine triphosphate	Thiamine pyrophosphate	Thiamine-monophosphate kinase	Phosphorylation	PathBank	31602464
MMDBr0019201	Hydrogen Ion	Carbon dioxide	Thiamine-phosphate synthase	Synthesis	PathBank	31602464
MMDBr0019202	Adenosine triphosphate	Thiamine pyrophosphate	Thiamine-monophosphate kinase	Phosphorylation	PathBank	31602464
MMDBr0019945	Hydrogen Ion	Thiamine monophosphate	Thiamine biosynthetic bifunctional enzyme	Thiamine biosynthesis	PathBank	31602464
MMDBr0019948	Water	Thiamine	Repressible acid phosphatase	Dephosphorylation	PathBank	31602464

Health Effects and Bioactivity

Health Outcome/Bioactivity	Metabolite Response/Effect	Evidence Type	Host and Biospecimen	Data Source	Reference
Alzheimer's disease		Association	Human Cerebrospinal Fluid (CSF)	HMDB	12111441

Microbial Sources

Superkingdom/Kingdom	Phylum	Total species	Hosts and Body Sites	Microbial Links
Bacteria	Proteobacteria	182	Human feces; Human sputum; Human ; Human unknown; Pig ; Human pleural fluid plaque; Human dental plaque; Human nasal swab; Human stool; Human feces; pleural fluid plaque; bal	Unknown; Metabolic reconstruction
Bacteria	Firmicutes	353	Human feces; Human pleural fluid plaque; Pig ; Human sputum; Human ; Human subgingival plaque; Human saliva; Human urine; Human mucosa; Human supragingival plaque; Cattle ; Human stool	Metabolic reconstruction
Bacteria	Actinobacteria	107	Human feces; Human sputum; Human bronchial brush; Human nasopharyngeal swab; Human pleural fluid plaque; Human dental plaque; Human ; Human supragingival plaque; Human mucosa; Human subgingival plaque; Human saliva	Metabolic reconstruction
Bacteria	Verrucomicrobia	1	Human ; Human feces	Metabolic reconstruction
Bacteria	Bacteroidetes	126	Human feces; Human appendix biopsy; Human ; Human stool; Human saliva; Human gastric fluid; Human urine; Human subgingival plaque; Human supragingival plaque	Metabolic reconstruction
Bacteria	Synergistetes	4	Human feces	Metabolic reconstruction
Bacteria	Spirochaetes	1	Human feces	Metabolic reconstruction
Archaea	Thaumarchaeota	2		Metabolic reconstruction
Bacteria	Fusobacteria	20	Human feces; Human	Metabolic reconstruction
Archaea	Euryarchaeota	5		Metabolic reconstruction
Bacteria	Candidatus melainabacteria	1	Human feces	Metabolic reconstruction
Bacteria	Tenericutes	1	Human feces	Metabolic reconstruction
Bacteria	Planctomycetes	1	Human feces	Metabolic reconstruction
Archaea	Crenarchaeota	1		Metabolic reconstruction
Eukaryota/Fungi	Ascomycota	1	Human feces; Human saliva	Unknown

Exposure Sources

Source Type	Source Sub-type	Species	Data Source	Reference

Host Biospecimen and Location

Host and Biospecimen	Status	Mean	Std	Units	Age	Sex	Health Condition	Data Source	Reference
Human Feces	Detected but not Quantified							HMDB
Human Cerebrospinal fluid (csf)	Detected and Quantified	0.0035	0.0038	uM	Adult (>18 years old)	Both	Alzheimer's disease	HMDB	12111441
Human Cerebrospinal fluid (csf)	Detected and Quantified	0.0043	0.0024	uM	Adult (>18 years old)	Both	Normal	HMDB	12111441

External Links

HMDB ID

Not Available

DrugBank ID

DB03416

Phenol Explorer Compound ID

Not Available

FooDB ID

FDB023043

KNApSAcK ID

Not Available

Chemspider ID

KEGG Compound ID

BioCyc ID

BiGG ID

Wikipedia Link

Thiamine monophosphate

METLIN ID

3488

PubChem Compound

3382778

PDB ID

Not Available

ChEBI ID

37574

Food Biomarker Ontology

Not Available

References

Synthesis Reference

Not Available

General References

Tallaksen CM, Bohmer T, Bell H: Concentrations of the water-soluble vitamins thiamin, ascorbic acid, and folic acid in serum and cerebrospinal fluid of healthy individuals. Am J Clin Nutr. 1992 Sep;56(3):559-64. doi: 10.1093/ajcn/56.3.559. [PubMed:1503069 ]
Tallaksen CM, Bohmer T, Bell H, Karlsen J: Concomitant determination of thiamin and its phosphate esters in human blood and serum by high-performance liquid chromatography. J Chromatogr. 1991 Mar 8;564(1):127-36. doi: 10.1016/0378-4347(91)80075-n. [PubMed:1860908 ]
Kimura M, Itokawa Y: Determination of thiamine and its phosphate esters in human and rat blood by high-performance liquid chromatography with post-column derivatization. J Chromatogr. 1985 Sep 20;332:181-8. doi: 10.1016/s0021-9673(01)83295-7. [PubMed:4055941 ]
Tallaksen CM, Bell H, Bohmer T: Thiamin and thiamin phosphate ester deficiency assessed by high performance liquid chromatography in four clinical cases of Wernicke encephalopathy. Alcohol Clin Exp Res. 1993 Jun;17(3):712-6. doi: 10.1111/j.1530-0277.1993.tb00825.x. [PubMed:8333605 ]
Tallaksen CM, Sande A, Bohmer T, Bell H, Karlsen J: Kinetics of thiamin and thiamin phosphate esters in human blood, plasma and urine after 50 mg intravenously or orally. Eur J Clin Pharmacol. 1993;44(1):73-8. doi: 10.1007/BF00315284. [PubMed:8436160 ]
Lu W, Kimball E, Rabinowitz JD: A high-performance liquid chromatography-tandem mass spectrometry method for quantitation of nitrogen-containing intracellular metabolites. J Am Soc Mass Spectrom. 2006 Jan;17(1):37-50. doi: 10.1016/j.jasms.2005.09.001. Epub 2005 Dec 15. [PubMed:16352439 ]

Showing metabocard for Thiamine monophosphate (MMDBc0029696)

MOL for #<Metabolite:0x00007fa4d9990040>

3D MOL for #<Metabolite:0x00007fa4d9990040>

3D SDF for #<Metabolite:0x00007fa4d9990040>

3D-SDF for #<Metabolite:0x00007fa4d9990040>

PDB for #<Metabolite:0x00007fa4d9990040>

3D PDB for #<Metabolite:0x00007fa4d9990040>

SMILES for #<Metabolite:0x00007fa4d9990040>

INCHI for #<Metabolite:0x00007fa4d9990040>

Structure for #<Metabolite:0x00007fa4d9990040>

3D Structure for #<Metabolite:0x00007fa4d9990040>