Mrv0541 08131209022D
45 47 0 0 0 0 999 V2000
1.8111 3.8205 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
2.2960 4.4879 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
10.5139 5.2082 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
4.3099 6.9486 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
9.9008 5.7602 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0
3.5253 6.6937 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0
0.9906 3.9067 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
10.0723 6.5672 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0
2.8579 7.1786 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0
9.4592 7.1192 0.0000 C 0 0 1 0 0 0 0 0 0 0 0 0
2.1904 6.6937 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0
8.6746 6.8643 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0
2.4454 5.9090 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0
8.5031 6.0573 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0
1.1400 5.3278 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
0.5057 3.2393 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0
0.6551 4.6604 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0
1.9605 5.2416 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0
11.2985 5.4631 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
10.8570 6.8221 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
2.8579 8.0036 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
9.6308 7.9262 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
1.4058 6.9486 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
8.0615 7.4163 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
0.8044 6.0815 0.0000 O 0 5 0 0 0 0 0 0 0 0 0 0
5.9626 5.8669 0.0000 O 0 5 0 0 0 0 0 0 0 0 0 0
5.4527 7.4361 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
6.5533 5.7413 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
7.6574 6.9675 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
4.9230 6.3966 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
3.2704 5.9090 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
9.1162 5.5053 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
7.7185 5.8024 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
6.4923 6.9064 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
5.7077 6.6515 0.0000 P 0 0 0 0 0 0 0 0 0 0 0 0
7.1054 6.3544 0.0000 P 0 0 0 0 0 0 0 0 0 0 0 0
10.5509 6.2681 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0
3.3679 7.5035 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0
10.8373 6.2581 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0
3.4205 7.7819 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0
10.2439 7.3742 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0
2.0614 7.5085 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0
8.8461 7.6713 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0
1.6305 6.0381 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0
7.8900 6.6093 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0
2 1 2 0 0 0 0
5 3 1 1 0 0 0
6 4 1 1 0 0 0
7 1 1 0 0 0 0
8 5 1 0 0 0 0
9 6 1 0 0 0 0
10 8 1 0 0 0 0
11 9 1 0 0 0 0
12 10 1 0 0 0 0
13 11 1 0 0 0 0
14 12 1 0 0 0 0
16 7 2 0 0 0 0
17 7 1 0 0 0 0
17 15 2 0 0 0 0
18 2 1 0 0 0 0
13 18 1 1 0 0 0
18 15 1 0 0 0 0
19 3 1 0 0 0 0
8 20 1 6 0 0 0
9 21 1 6 0 0 0
10 22 1 1 0 0 0
11 23 1 6 0 0 0
12 24 1 6 0 0 0
25 15 1 0 0 0 0
30 4 1 0 0 0 0
31 6 1 0 0 0 0
31 13 1 0 0 0 0
32 5 1 0 0 0 0
32 14 1 0 0 0 0
14 33 1 6 0 0 0
35 26 1 0 0 0 0
35 27 2 0 0 0 0
35 30 1 0 0 0 0
35 34 1 0 0 0 0
36 28 1 0 0 0 0
36 29 2 0 0 0 0
36 33 1 0 0 0 0
36 34 1 0 0 0 0
5 37 1 6 0 0 0
6 38 1 6 0 0 0
8 39 1 1 0 0 0
9 40 1 1 0 0 0
10 41 1 6 0 0 0
11 42 1 1 0 0 0
12 43 1 1 0 0 0
13 44 1 6 0 0 0
14 45 1 1 0 0 0
M CHG 2 25 -1 26 -1
M END
> <DATABASE_ID>
MMDBc0029762
> <DATABASE_NAME>
MIME
> <SMILES>
[H][C@]1(COP([O-])(=O)OP(O)(=O)O[C@@]2([H])O[C@]([H])(CO)[C@@]([H])(O)[C@]([H])(O)[C@@]2([H])O)O[C@@]([H])(N2C=CC(=N)N=C2[O-])[C@]([H])(O)[C@]1([H])O
> <INCHI_IDENTIFIER>
InChI=1S/C15H25N3O16P2/c16-7-1-2-18(15(25)17-7)13-11(23)9(21)6(31-13)4-30-35(26,27)34-36(28,29)33-14-12(24)10(22)8(20)5(3-19)32-14/h1-2,5-6,8-14,19-24H,3-4H2,(H,26,27)(H,28,29)(H2,16,17,25)/p-2/t5-,6-,8-,9-,10+,11-,12-,13-,14-/m1/s1
> <INCHI_KEY>
CGPHZDRCVSLMCF-JZMIEXBBSA-L
> <FORMULA>
C15H23N3O16P2
> <MOLECULAR_WEIGHT>
563.3011
> <EXACT_MASS>
563.055354727
> <JCHEM_ACCEPTOR_COUNT>
16
> <JCHEM_AVERAGE_POLARIZABILITY>
46.148680521874766
> <JCHEM_BIOAVAILABILITY>
0
> <JCHEM_DONOR_COUNT>
8
> <JCHEM_FORMAL_CHARGE>
-2
> <JCHEM_GHOSE_FILTER>
0
> <JCHEM_IUPAC>
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-({[hydroxy({[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy})phosphoryl phosphonato]oxy}methyl)oxolan-2-yl]-4-imino-1,4-dihydropyrimidin-2-olate
> <ALOGPS_LOGP>
-1.80
> <JCHEM_LOGP>
-5.985842775894131
> <ALOGPS_LOGS>
-1.28
> <JCHEM_MDDR_LIKE_RULE>
1
> <JCHEM_NUMBER_OF_RINGS>
3
> <JCHEM_PHYSIOLOGICAL_CHARGE>
-2
> <JCHEM_PKA>
3.150749871656981
> <JCHEM_PKA_STRONGEST_ACIDIC>
1.6682640339236743
> <JCHEM_PKA_STRONGEST_BASIC>
3.264618244679447
> <JCHEM_POLAR_SURFACE_AREA>
307.4700000000001
> <JCHEM_REFRACTIVITY>
129.27609999999999
> <JCHEM_ROTATABLE_BOND_COUNT>
9
> <JCHEM_RULE_OF_FIVE>
0
> <ALOGPS_SOLUBILITY>
3.16e+01 g/l
> <JCHEM_TRADITIONAL_IUPAC>
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[({hydroxy[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphosphoryl phosphonato}oxy)methyl]oxolan-2-yl]-4-iminopyrimidin-2-olate
> <JCHEM_VEBER_RULE>
0
$$$$