Record Information
Version1.0
StatusDetected and Quantified
Creation Date2021-11-17 23:53:28 UTC
Update Date2022-08-31 17:39:37 UTC
Metabolite IDMMDBc0030088
Metabolite Identification
Common NamePropanoyl phosphate
DescriptionPropanoyl phosphate is an alkylphosphate. It is generated during the course of threonine degradation via propanoyl-CoA. The first reaction in the anaerobic threonine dehydratase pathway is catalyzed by catabolic threonine dehydratase which degrades threonine to 2-oxobutanoate (alpha-ketobutyrate) and ammonia. The 2-oxobutanoate then undergoes lyase cleavage with the addition of coenzyme A to form propanoyl-CoA and formate. Once propanoyl-CoA is formed, it is processed via propionyl-phosphate to propionate in a reaction sequence that produces ATP. Acetate kinase AckA can also utilize propionate as a substrate in the final reaction. The enzymes in this pathway are also able to process L-serine, with pyruvate as the final product [EcoCyc].
Structure
Synonyms
ValueSource
(Propanoyloxy)phosphonate(2-)ChEBI
Propanoyl phosphate dianionChEBI
(Propanoyloxy)phosphonic acid(2-)Generator
Propanoyl phosphoric acid dianionGenerator
Propanoyl phosphoric acidGenerator
Molecular FormulaC3H5O5P
Average Mass152.043
Monoisotopic Mass151.988557419
IUPAC Name(propanoyloxy)phosphonate
Traditional Namepropanoyl phosphate
CAS Registry Number121-69-7
SMILES
CCC(=O)OP([O-])([O-])=O
InChI Identifier
InChI=1S/C3H7O5P/c1-2-3(4)8-9(5,6)7/h2H2,1H3,(H2,5,6,7)/p-2
InChI KeyFMNMEQSRDWIBFO-UHFFFAOYSA-L