Record Information
Version1.0
StatusDetected and Quantified
Creation Date2021-11-17 23:53:48 UTC
Update Date2024-10-13 14:32:50 UTC
Metabolite IDMMDBc0030097
Metabolite Identification
Common NameSiroheme
DescriptionSiroheme belongs to the class of Precorrins. These are intermediates formed by methylation at one or more of the four rings prior to the formation of the macrocyclic corrin ring. (inferred from compound structure)Siroheme (or sirohaem) is a heme-like prosthetic group used by some enzymes to accomplish the six-electron reduction of sulfur and nitrogen. Siroheme is synthesized from uroporphyrinogen III, a heme and vitamin B12 precursor. It plays a major role in the sulfur assimilation pathway: converting sulfite to a biologically useful sulfide, which can be incorporated into the organic compound homocysteine. (WikiPedia)
Structure
Synonyms
ValueSource
SirohaemChEBI
Octacarboxylate iron-tetrahydroporphyrinMeSH
Molecular FormulaC42H44FeN4O16
Average Mass916.661
Monoisotopic Mass916.210173513
IUPAC NameNot Available
Traditional NameNot Available
CAS Registry Number52553-42-1
SMILESNot Available
InChI Identifier
InChI=1S/C42H46N4O16.Fe/c1-41(17-39(59)60)23(5-9-35(51)52)29-14-27-21(11-37(55)56)19(3-7-33(47)48)25(43-27)13-26-20(4-8-34(49)50)22(12-38(57)58)28(44-26)15-31-42(2,18-40(61)62)24(6-10-36(53)54)30(46-31)16-32(41)45-29;/h13-16,23-24H,3-12,17-18H2,1-2H3,(H10,43,44,45,46,47,48,49,50,51,52,53,54,55,56,57,58,59,60,61,62);/q;+2/p-2/t23-,24-,41+,42+;/m1./s1
InChI KeyDLKSSIHHLYNIKN-QIISWYHFSA-L