MiMeDB: Showing metabocard for PG(14:0/14:0) (MMDBc0030227)

Record Information

Version

1.0

Status

Detected and Quantified

Creation Date

2021-11-17 23:59:09 UTC

Update Date

2022-08-31 17:41:32 UTC

Metabolite ID

MMDBc0030227

Metabolite Identification

Common Name

PG(14:0/14:0)

Description

PG(14:0/14:0) is a phosphatidylglycerol. Phosphatidylglycerols consist of a glycerol 3-phosphate backbone esterified to either saturated or unsaturated fatty acids on carbons 1 and 2. As is the case with diacylglycerols, phosphatidylglycerols can have many different combinations of fatty acids of varying lengths and saturation attached to the C-1 and C-2 positions. PG(14:0/14:0), in particular, consists of two tetradecanoyl chains at positions C-1 and C-2. In E. coli glycerophospholipid metabolism, phosphatidylglycerol is formed from phosphatidic acid (1,2-diacyl-sn-glycerol 3-phosphate) by a sequence of enzymatic reactions that proceeds via two intermediates, cytidine diphosphate diacylglycerol (CDP-diacylglycerol) and phosphatidylglycerophosphate (PGP, a phosphorylated phosphatidylglycerol). Phosphatidylglycerols, along with CDP-diacylglycerol, also serve as precursor molecules for the synthesis of cardiolipin, a phospholipid found in membranes.

Structure

MOL SDF PDB SMILES InChI

PG(14:0/14:0)
  Mrv1652308101905202D          

 47 46  0  0  1  0            999 V2000
   14.0374  -24.1595    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   13.3624  -24.5493    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   12.6871  -24.1595    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   14.7126  -24.5493    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   12.0120  -24.5493    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   12.8354  -25.3289    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   15.3878  -24.1595    0.0000 P   0  0  0  0  0  0  0  0  0  0  0  0
   14.9979  -23.4844    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   15.7775  -24.8347    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   16.0628  -23.7697    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   16.7379  -24.1595    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   17.4131  -23.7697    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   18.0883  -24.1595    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   13.9501  -25.3586    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
   18.7261  -23.7330    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   17.9894  -23.0847    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
   16.8011  -23.0847    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   11.2975  -24.1369    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   11.2975  -23.3654    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   10.5834  -24.5500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    9.8693  -24.1369    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    9.1551  -24.5500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.4410  -24.1369    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.7268  -24.5500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.0127  -24.1369    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.2985  -24.5500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.5844  -24.1369    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.8703  -24.5500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.1561  -24.1369    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.4420  -24.5500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7279  -24.1369    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0137  -24.5500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   12.1210  -25.7414    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   12.1210  -26.5128    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   11.4069  -25.3283    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   10.6928  -25.7414    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    9.9786  -25.3283    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    9.2645  -25.7414    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.5504  -25.3283    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.8362  -25.7414    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.1221  -25.3283    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.4079  -25.7414    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.6938  -25.3283    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.9796  -25.7414    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2655  -25.3283    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5514  -25.7414    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8373  -25.3283    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  2  1  1  0  0  0  0
  2  6  1  0  0  0  0
  2 14  1  1  0  0  0
  3  2  1  0  0  0  0
  4  1  1  0  0  0  0
  5  3  1  0  0  0  0
  5 18  1  0  0  0  0
  7  4  1  0  0  0  0
  8  7  2  0  0  0  0
  9  7  1  0  0  0  0
 10  7  1  0  0  0  0
 11 10  1  0  0  0  0
 12 11  1  0  0  0  0
 12 16  1  6  0  0  0
 12 17  1  0  0  0  0
 13 12  1  0  0  0  0
 13 15  1  0  0  0  0
 18 19  2  0  0  0  0
 18 20  1  0  0  0  0
 20 21  1  0  0  0  0
 21 22  1  0  0  0  0
 22 23  1  0  0  0  0
 23 24  1  0  0  0  0
 24 25  1  0  0  0  0
 25 26  1  0  0  0  0
 26 27  1  0  0  0  0
 27 28  1  0  0  0  0
 28 29  1  0  0  0  0
 29 30  1  0  0  0  0
 30 31  1  0  0  0  0
 31 32  1  0  0  0  0
 33  6  1  0  0  0  0
 33 34  2  0  0  0  0
 33 35  1  0  0  0  0
 35 36  1  0  0  0  0
 36 37  1  0  0  0  0
 37 38  1  0  0  0  0
 38 39  1  0  0  0  0
 39 40  1  0  0  0  0
 40 41  1  0  0  0  0
 41 42  1  0  0  0  0
 42 43  1  0  0  0  0
 43 44  1  0  0  0  0
 44 45  1  0  0  0  0
 45 46  1  0  0  0  0
 46 47  1  0  0  0  0
M  END

PG(14:0/14:0)
  Mrv1652308101905202D          

 47 46  0  0  1  0            999 V2000
   14.0374  -24.1595    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   13.3624  -24.5493    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   12.6871  -24.1595    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   14.7126  -24.5493    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   12.0120  -24.5493    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   12.8354  -25.3289    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   15.3878  -24.1595    0.0000 P   0  0  0  0  0  0  0  0  0  0  0  0
   14.9979  -23.4844    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   15.7775  -24.8347    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   16.0628  -23.7697    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   16.7379  -24.1595    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   17.4131  -23.7697    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   18.0883  -24.1595    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   13.9501  -25.3586    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
   18.7261  -23.7330    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   17.9894  -23.0847    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
   16.8011  -23.0847    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   11.2975  -24.1369    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   11.2975  -23.3654    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   10.5834  -24.5500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    9.8693  -24.1369    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    9.1551  -24.5500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.4410  -24.1369    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.7268  -24.5500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.0127  -24.1369    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.2985  -24.5500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.5844  -24.1369    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.8703  -24.5500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.1561  -24.1369    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.4420  -24.5500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7279  -24.1369    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0137  -24.5500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   12.1210  -25.7414    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   12.1210  -26.5128    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   11.4069  -25.3283    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   10.6928  -25.7414    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    9.9786  -25.3283    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    9.2645  -25.7414    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.5504  -25.3283    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.8362  -25.7414    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.1221  -25.3283    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.4079  -25.7414    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.6938  -25.3283    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.9796  -25.7414    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2655  -25.3283    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5514  -25.7414    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8373  -25.3283    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  2  1  1  0  0  0  0
  2  6  1  0  0  0  0
  2 14  1  1  0  0  0
  3  2  1  0  0  0  0
  4  1  1  0  0  0  0
  5  3  1  0  0  0  0
  5 18  1  0  0  0  0
  7  4  1  0  0  0  0
  8  7  2  0  0  0  0
  9  7  1  0  0  0  0
 10  7  1  0  0  0  0
 11 10  1  0  0  0  0
 12 11  1  0  0  0  0
 12 16  1  6  0  0  0
 12 17  1  0  0  0  0
 13 12  1  0  0  0  0
 13 15  1  0  0  0  0
 18 19  2  0  0  0  0
 18 20  1  0  0  0  0
 20 21  1  0  0  0  0
 21 22  1  0  0  0  0
 22 23  1  0  0  0  0
 23 24  1  0  0  0  0
 24 25  1  0  0  0  0
 25 26  1  0  0  0  0
 26 27  1  0  0  0  0
 27 28  1  0  0  0  0
 28 29  1  0  0  0  0
 29 30  1  0  0  0  0
 30 31  1  0  0  0  0
 31 32  1  0  0  0  0
 33  6  1  0  0  0  0
 33 34  2  0  0  0  0
 33 35  1  0  0  0  0
 35 36  1  0  0  0  0
 36 37  1  0  0  0  0
 37 38  1  0  0  0  0
 38 39  1  0  0  0  0
 39 40  1  0  0  0  0
 40 41  1  0  0  0  0
 41 42  1  0  0  0  0
 42 43  1  0  0  0  0
 43 44  1  0  0  0  0
 44 45  1  0  0  0  0
 45 46  1  0  0  0  0
 46 47  1  0  0  0  0
M  END
> <DATABASE_ID>
MMDBc0030227

> <DATABASE_NAME>
MIME

> <SMILES>
[H][C@](O)(CO)COP(O)(=O)OC[C@@]([H])(COC(=O)CCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCC

> <INCHI_IDENTIFIER>
InChI=1S/C34H67O10P/c1-3-5-7-9-11-13-15-17-19-21-23-25-33(37)41-29-32(30-43-45(39,40)42-28-31(36)27-35)44-34(38)26-24-22-20-18-16-14-12-10-8-6-4-2/h31-32,35-36H,3-30H2,1-2H3,(H,39,40)/t31-,32+/m0/s1

> <INCHI_KEY>
BPHQZTVXXXJVHI-AJQTZOPKSA-N

> <FORMULA>
C34H67O10P

> <MOLECULAR_WEIGHT>
666.874

> <EXACT_MASS>
666.447185355

> <JCHEM_ACCEPTOR_COUNT>
6

> <JCHEM_ATOM_COUNT>
112

> <JCHEM_AVERAGE_POLARIZABILITY>
78.99783513479566

> <JCHEM_BIOAVAILABILITY>
0

> <JCHEM_DONOR_COUNT>
3

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
[(2R)-2,3-bis(tetradecanoyloxy)propoxy][(2S)-2,3-dihydroxypropoxy]phosphinic acid

> <ALOGPS_LOGP>
6.79

> <JCHEM_LOGP>
9.158776859333333

> <ALOGPS_LOGS>
-6.38

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
0

> <JCHEM_PHYSIOLOGICAL_CHARGE>
-1

> <JCHEM_PKA>
13.641245576372423

> <JCHEM_PKA_STRONGEST_ACIDIC>
1.8907737771908404

> <JCHEM_PKA_STRONGEST_BASIC>
-2.9689647678483633

> <JCHEM_POLAR_SURFACE_AREA>
148.82000000000002

> <JCHEM_REFRACTIVITY>
176.9049

> <JCHEM_ROTATABLE_BOND_COUNT>
36

> <JCHEM_RULE_OF_FIVE>
0

> <ALOGPS_SOLUBILITY>
2.81e-04 g/l

> <JCHEM_TRADITIONAL_IUPAC>
(2R)-2,3-bis(tetradecanoyloxy)propoxy((2S)-2,3-dihydroxypropoxy)phosphinic acid

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 10-AUG-19   NONE
TITLE     NULL                                                        
COMPND    MOLECULE: PG(14:0/14:0)                                     
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   10-AUG-19         0                                  
HETATM    1  C   UNK     0      26.203 -45.098   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0      24.943 -45.825   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0      23.683 -45.098   0.000  0.00  0.00           C+0
HETATM    4  O   UNK     0      27.464 -45.825   0.000  0.00  0.00           O+0
HETATM    5  O   UNK     0      22.422 -45.825   0.000  0.00  0.00           O+0
HETATM    6  O   UNK     0      23.959 -47.281   0.000  0.00  0.00           O+0
HETATM    7  P   UNK     0      28.724 -45.098   0.000  0.00  0.00           P+0
HETATM    8  O   UNK     0      27.996 -43.837   0.000  0.00  0.00           O+0
HETATM    9  O   UNK     0      29.451 -46.358   0.000  0.00  0.00           O+0
HETATM   10  O   UNK     0      29.984 -44.370   0.000  0.00  0.00           O+0
HETATM   11  C   UNK     0      31.244 -45.098   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0      32.504 -44.370   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0      33.765 -45.098   0.000  0.00  0.00           C+0
HETATM   14  H   UNK     0      26.040 -47.336   0.000  0.00  0.00           H+0
HETATM   15  O   UNK     0      34.955 -44.302   0.000  0.00  0.00           O+0
HETATM   16  H   UNK     0      33.580 -43.091   0.000  0.00  0.00           H+0
HETATM   17  O   UNK     0      31.362 -43.091   0.000  0.00  0.00           O+0
HETATM   18  C   UNK     0      21.089 -45.055   0.000  0.00  0.00           C+0
HETATM   19  O   UNK     0      21.089 -43.615   0.000  0.00  0.00           O+0
HETATM   20  C   UNK     0      19.756 -45.827   0.000  0.00  0.00           C+0
HETATM   21  C   UNK     0      18.423 -45.055   0.000  0.00  0.00           C+0
HETATM   22  C   UNK     0      17.090 -45.827   0.000  0.00  0.00           C+0
HETATM   23  C   UNK     0      15.756 -45.055   0.000  0.00  0.00           C+0
HETATM   24  C   UNK     0      14.423 -45.827   0.000  0.00  0.00           C+0
HETATM   25  C   UNK     0      13.090 -45.055   0.000  0.00  0.00           C+0
HETATM   26  C   UNK     0      11.757 -45.827   0.000  0.00  0.00           C+0
HETATM   27  C   UNK     0      10.424 -45.055   0.000  0.00  0.00           C+0
HETATM   28  C   UNK     0       9.091 -45.827   0.000  0.00  0.00           C+0
HETATM   29  C   UNK     0       7.758 -45.055   0.000  0.00  0.00           C+0
HETATM   30  C   UNK     0       6.425 -45.827   0.000  0.00  0.00           C+0
HETATM   31  C   UNK     0       5.092 -45.055   0.000  0.00  0.00           C+0
HETATM   32  C   UNK     0       3.759 -45.827   0.000  0.00  0.00           C+0
HETATM   33  C   UNK     0      22.626 -48.051   0.000  0.00  0.00           C+0
HETATM   34  O   UNK     0      22.626 -49.491   0.000  0.00  0.00           O+0
HETATM   35  C   UNK     0      21.293 -47.279   0.000  0.00  0.00           C+0
HETATM   36  C   UNK     0      19.960 -48.051   0.000  0.00  0.00           C+0
HETATM   37  C   UNK     0      18.627 -47.279   0.000  0.00  0.00           C+0
HETATM   38  C   UNK     0      17.294 -48.051   0.000  0.00  0.00           C+0
HETATM   39  C   UNK     0      15.961 -47.279   0.000  0.00  0.00           C+0
HETATM   40  C   UNK     0      14.628 -48.051   0.000  0.00  0.00           C+0
HETATM   41  C   UNK     0      13.295 -47.279   0.000  0.00  0.00           C+0
HETATM   42  C   UNK     0      11.961 -48.051   0.000  0.00  0.00           C+0
HETATM   43  C   UNK     0      10.628 -47.279   0.000  0.00  0.00           C+0
HETATM   44  C   UNK     0       9.295 -48.051   0.000  0.00  0.00           C+0
HETATM   45  C   UNK     0       7.962 -47.279   0.000  0.00  0.00           C+0
HETATM   46  C   UNK     0       6.629 -48.051   0.000  0.00  0.00           C+0
HETATM   47  C   UNK     0       5.296 -47.279   0.000  0.00  0.00           C+0
CONECT    1    2    4                                                       
CONECT    2    1    6   14    3                                             
CONECT    3    2    5                                                       
CONECT    4    1    7                                                       
CONECT    5    3   18                                                       
CONECT    6    2   33                                                       
CONECT    7    4    8    9   10                                             
CONECT    8    7                                                            
CONECT    9    7                                                            
CONECT   10    7   11                                                       
CONECT   11   10   12                                                       
CONECT   12   11   16   17   13                                             
CONECT   13   12   15                                                       
CONECT   14    2                                                            
CONECT   15   13                                                            
CONECT   16   12                                                            
CONECT   17   12                                                            
CONECT   18    5   19   20                                                  
CONECT   19   18                                                            
CONECT   20   18   21                                                       
CONECT   21   20   22                                                       
CONECT   22   21   23                                                       
CONECT   23   22   24                                                       
CONECT   24   23   25                                                       
CONECT   25   24   26                                                       
CONECT   26   25   27                                                       
CONECT   27   26   28                                                       
CONECT   28   27   29                                                       
CONECT   29   28   30                                                       
CONECT   30   29   31                                                       
CONECT   31   30   32                                                       
CONECT   32   31                                                            
CONECT   33    6   34   35                                                  
CONECT   34   33                                                            
CONECT   35   33   36                                                       
CONECT   36   35   37                                                       
CONECT   37   36   38                                                       
CONECT   38   37   39                                                       
CONECT   39   38   40                                                       
CONECT   40   39   41                                                       
CONECT   41   40   42                                                       
CONECT   42   41   43                                                       
CONECT   43   42   44                                                       
CONECT   44   43   45                                                       
CONECT   45   44   46                                                       
CONECT   46   45   47                                                       
CONECT   47   46                                                            
MASTER        0    0    0    0    0    0    0    0   47    0   92    0
END

Synonyms

Value	Source
C14:0 PG	ChEBI
C14:0 Phosphatidylglycerol	ChEBI
Dimyristoyl phosphatidylglycerol	ChEBI
Dimyristoylphosphatidylglycerol	ChEBI
1,2-Dimyristoyl-sn-glycerol-3-phosphoglycerol	MeSH
1,2-Dimyristoyl-sn-glycero-3-(phospho-rac-(1-glycerol))	MeSH
DMPG	MeSH

Molecular Formula

C₃₄H₆₇O₁₀P

Average Mass

666.874

Monoisotopic Mass

666.447185355

IUPAC Name

[(2R)-2,3-bis(tetradecanoyloxy)propoxy][(2S)-2,3-dihydroxypropoxy]phosphinic acid

Traditional Name

(2R)-2,3-bis(tetradecanoyloxy)propoxy((2S)-2,3-dihydroxypropoxy)phosphinic acid

CAS Registry Number

Not Available

SMILES

[H][C@](O)(CO)COP(O)(=O)OC[C@@]([H])(COC(=O)CCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCC

InChI Identifier

InChI=1S/C34H67O10P/c1-3-5-7-9-11-13-15-17-19-21-23-25-33(37)41-29-32(30-43-45(39,40)42-28-31(36)27-35)44-34(38)26-24-22-20-18-16-14-12-10-8-6-4-2/h31-32,35-36H,3-30H2,1-2H3,(H,39,40)/t31-,32+/m0/s1

InChI Key

BPHQZTVXXXJVHI-AJQTZOPKSA-N

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as phosphatidylglycerols. These are glycerophosphoglycerols in which two fatty acids are bonded to the 1-glycerol moiety through ester linkages. As is the case with diacylglycerols, phosphatidylglycerols can have many different combinations of fatty acids of varying lengths and saturation attached to the C-1 and C-2 positions.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Glycerophospholipids

Sub Class

Glycerophosphoglycerols

Direct Parent

Phosphatidylglycerols

Alternative Parents

Substituents

1,2-diacylglycerophosphoglycerol
Fatty acid ester
Dialkyl phosphate
Dicarboxylic acid or derivatives
Organic phosphoric acid derivative
Phosphoric acid ester
Alkyl phosphate
Fatty acyl
1,2-diol
Carboxylic acid ester
Secondary alcohol
Carboxylic acid derivative
Organic oxide
Organooxygen compound
Alcohol
Organic oxygen compound
Primary alcohol
Carbonyl group
Hydrocarbon derivative
Aliphatic acyclic compound

Molecular Framework

Aliphatic acyclic compounds

External Descriptors

Diacylglycerophosphoglycerols (LMGP04010005 )

Functional Ontology

Not Available

Physical Properties

State

Expected Solid

Predicted Properties

Property	Value	Source
Water Solubility	0.00028 g/L	ALOGPS
logP	6.79	ALOGPS
logP	9.16	ChemAxon
logS	-6.4	ALOGPS
pKa (Strongest Acidic)	1.89	ChemAxon
pKa (Strongest Basic)	-3	ChemAxon
Physiological Charge	-1	ChemAxon
Hydrogen Acceptor Count	6	ChemAxon
Hydrogen Donor Count	3	ChemAxon
Polar Surface Area	148.82 Å²	ChemAxon
Rotatable Bond Count	36	ChemAxon
Refractivity	176.9 m³·mol⁻¹	ChemAxon
Polarizability	79 Å³	ChemAxon
Number of Rings	0	ChemAxon
Bioavailability	No	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

Spectra

Spectrum Type	Description	Splash Key	Deposition Date	View
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (TMS_2_3) - 70eV, Positive	Not Available	2022-08-08	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 10V, Positive	splash10-02bk-4260906000-117e3343dd030813de29	2019-02-22	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 20V, Positive	splash10-07dt-8581912000-328635d3b4fa818512a6	2019-02-22	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 40V, Positive	splash10-0ara-9370631000-7e6beb124384e9c30762	2019-02-22	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 10V, Negative	splash10-0ar0-1290414000-f87b6bff58d62d266b70	2019-02-23	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 20V, Negative	splash10-004i-6391210000-0d720d25c0561490884d	2019-02-23	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 40V, Negative	splash10-004i-9010000000-207d46a708551efbeb40	2019-02-23	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 100 MHz, H₂O, predicted)		2022-08-17	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)		2022-08-17	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 1000 MHz, H₂O, predicted)		2022-08-17	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)		2022-08-17	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 200 MHz, H₂O, predicted)		2022-08-17	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)		2022-08-17	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 300 MHz, H₂O, predicted)		2022-08-17	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)		2022-08-17	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 400 MHz, H₂O, predicted)		2022-08-17	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)		2022-08-17	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 500 MHz, H₂O, predicted)		2022-08-17	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)		2022-08-17	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 600 MHz, H₂O, predicted)		2022-08-17	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)		2022-08-17	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 700 MHz, H₂O, predicted)		2022-08-17	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)		2022-08-17	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 800 MHz, H₂O, predicted)		2022-08-17	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)		2022-08-17	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 900 MHz, H₂O, predicted)		2022-08-17	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)		2022-08-17	View Spectrum

Biological Properties

Cellular Locations

Not Available

Biospecimen Locations

Not Available

Tissue Locations

Not Available

Associated OMIM IDs

114500 (Colorectal cancer)
610247 (Eosinophilic esophagitis)

Human Proteins and Enzymes

Protein ID	Protein Name	Protein Type	Uniprot ID	Species

Human Pathways

Pathways

Name	SMPDB/PathBank

Metabolic Reactions

Reaction ID	Precursor	Product	Enzyme	Reaction Type	Data Source	Reference
MMDBr0018728	Water	Phosphate	Phosphatidylglycerophosphatase B	Dephosphorylation	PathBank	31602464
MMDBr0018729	PE(14:0/16:0)	Ethanolamine	Cardiolipin synthase C	Synthesis	PathBank	31602464
MMDBr0018733	PG(14:0/14:0)	Ethanolamine	Cardiolipin synthase C	Synthesis	PathBank	31602464
MMDBr0018743	PE(16:0/18:1(9Z))	Ethanolamine	Cardiolipin synthase C	Synthesis	PathBank	31602464
MMDBr0018747	PE(16:1(9Z)/16:1(9Z))	Ethanolamine	Cardiolipin synthase C	Synthesis	PathBank	31602464
MMDBr0018748	PG(14:0/14:0)	Ethanolamine	Cardiolipin synthase C	Synthesis	PathBank	31602464
MMDBr0018810	PG(14:0/14:0)	Ethanolamine	Cardiolipin synthase C	Synthesis	PathBank	31602464
MMDBr0018937	PG(14:0/14:0)	Ethanolamine	Cardiolipin synthase C	Synthesis	PathBank	31602464
MMDBr0018981	PG(14:0/14:0)	Ethanolamine	Cardiolipin synthase C	Synthesis	PathBank	31602464
MMDBr0018984	PG(14:0/14:0)	Ethanolamine	Cardiolipin synthase C	Synthesis	PathBank	31602464
MMDBr0018991	PG(14:0/14:0)	Ethanolamine	Cardiolipin synthase C	Synthesis	PathBank	31602464
MMDBr0018996	PG(14:0/14:0)	Ethanolamine	Cardiolipin synthase C	Synthesis	PathBank	31602464
MMDBr0019001	PG(14:0/14:0)	Ethanolamine	Cardiolipin synthase C	Synthesis	PathBank	31602464
MMDBr0019009	PG(14:0/14:0)	Ethanolamine	Cardiolipin synthase C	Synthesis	PathBank	31602464
MMDBr0019014	PG(14:0/14:0)	Ethanolamine	Cardiolipin synthase C	Synthesis	PathBank	31602464
MMDBr0019025	PG(14:0/14:0)	Ethanolamine	Cardiolipin synthase C	Synthesis	PathBank	31602464
MMDBr0019032	PG(14:0/14:0)	Ethanolamine	Cardiolipin synthase C	Synthesis	PathBank	31602464
MMDBr0019038	PG(14:0/14:0)	Ethanolamine	Cardiolipin synthase C	Synthesis	PathBank	31602464
MMDBr0019068	PG(14:0/14:0)	Ethanolamine	Cardiolipin synthase C	Synthesis	PathBank	31602464
MMDBr0019071	PG(14:0/14:0)	Ethanolamine	Cardiolipin synthase C	Synthesis	PathBank	31602464
MMDBr0020690	PG(14:0/14:0)	Glycerol	Cardiolipin synthase A	Synthesis	PathBank	31602464
MMDBr0020707	PG(14:0/14:0)	Glycerol	Cardiolipin synthase A	Synthesis	PathBank	31602464
MMDBr0020713	PE(16:0/14:0)	Ethanolamine	Cardiolipin synthase C	Synthesis	PathBank	31602464
MMDBr0020716	PG(14:0/14:0)	Glycerol	Cardiolipin synthase A	Synthesis	PathBank	31602464
MMDBr0020740	PE(16:0/16:0)	Ethanolamine	Cardiolipin synthase C	Synthesis	PathBank	31602464
MMDBr0020742	PG(16:0/16:0)	Glycerol	Cardiolipin synthase A	Synthesis	PathBank	31602464
MMDBr0020774	PE(16:0/16:1(9Z))	Ethanolamine	Cardiolipin synthase C	Synthesis	PathBank	31602464
MMDBr0020776	PG(16:1(9Z)/16:0)	Glycerol	Cardiolipin synthase A	Synthesis	PathBank	31602464
MMDBr0020803	PG(14:0/14:0)	Glycerol	Cardiolipin synthase A	Synthesis	PathBank	31602464
MMDBr0020838	PE(16:1(9Z)/16:0)	Ethanolamine	Cardiolipin synthase C	Synthesis	PathBank	31602464
MMDBr0020840	PG(16:0/16:1(9Z))	Glycerol	Cardiolipin synthase A	Synthesis	PathBank	31602464
MMDBr0020870	PG(16:1(9Z)/16:1(9Z))	Glycerol	Cardiolipin synthase A	Synthesis	PathBank	31602464
MMDBr0020892	PG(14:0/14:0)	Glycerol	Cardiolipin synthase A	Synthesis	PathBank	31602464
MMDBr0020900	PG(14:0/14:0)	Ethanolamine	Cardiolipin synthase C	Synthesis	PathBank	31602464
MMDBr0020902	PG(14:0/14:0)	Glycerol	Cardiolipin synthase A	Synthesis	PathBank	31602464
MMDBr0020917	PG(14:0/14:0)	Ethanolamine	Cardiolipin synthase C	Synthesis	PathBank	31602464
MMDBr0020919	PG(14:0/14:0)	Glycerol	Cardiolipin synthase A	Synthesis	PathBank	31602464
MMDBr0020936	PG(14:0/14:0)	Ethanolamine	Cardiolipin synthase C	Synthesis	PathBank	31602464
MMDBr0020938	PG(14:0/14:0)	Glycerol	Cardiolipin synthase A	Synthesis	PathBank	31602464
MMDBr0020958	PG(14:0/14:0)	Glycerol	Cardiolipin synthase A	Synthesis	PathBank	31602464
MMDBr0020966	PG(14:0/14:0)	Glycerol	Cardiolipin synthase A	Synthesis	PathBank	31602464
MMDBr0020971	PG(14:0/14:0)	Glycerol	Cardiolipin synthase A	Synthesis	PathBank	31602464
MMDBr0020996	PG(14:0/14:0)	Glycerol	Cardiolipin synthase A	Synthesis	PathBank	31602464
MMDBr0021000	PG(14:0/14:0)	Glycerol	Cardiolipin synthase A	Synthesis	PathBank	31602464
MMDBr0021008	PG(14:0/14:0)	Ethanolamine	Cardiolipin synthase C	Synthesis	PathBank	31602464
MMDBr0021011	PG(14:0/14:0)	Glycerol	Cardiolipin synthase A	Synthesis	PathBank	31602464
MMDBr0021017	PG(14:0/14:0)	Ethanolamine	Cardiolipin synthase C	Synthesis	PathBank	31602464
MMDBr0021019	PG(14:0/14:0)	Glycerol	Cardiolipin synthase A	Synthesis	PathBank	31602464
MMDBr0022307	PG(14:0/14:0)	Ethanolamine	Cardiolipin synthase C	Synthesis	PathBank	31602464
MMDBr0022308	PG(14:0/14:0)	Glycerol	Cardiolipin synthase A	Synthesis	PathBank	31602464
MMDBr0022430	PG(14:0/14:0)	Ethanolamine	Cardiolipin synthase C	Synthesis	PathBank	31602464
MMDBr0022431	PG(14:0/14:0)	Glycerol	Cardiolipin synthase A	Synthesis	PathBank	31602464
MMDBr0022598	PG(14:0/14:0)	Ethanolamine	Cardiolipin synthase C	Synthesis	PathBank	31602464
MMDBr0022599	PG(14:0/14:0)	Glycerol	Cardiolipin synthase A	Synthesis	PathBank	31602464
MMDBr0022674	PG(14:0/14:0)	Ethanolamine	Cardiolipin synthase C	Synthesis	PathBank	31602464
MMDBr0022675	PG(14:0/14:0)	Glycerol	Cardiolipin synthase A	Synthesis	PathBank	31602464
MMDBr0022693	PG(14:0/14:0)	Ethanolamine	Cardiolipin synthase C	Synthesis	PathBank	31602464
MMDBr0022694	PG(14:0/14:0)	Glycerol	Cardiolipin synthase A	Synthesis	PathBank	31602464
MMDBr0022721	PG(14:0/14:0)	Ethanolamine	Cardiolipin synthase C	Synthesis	PathBank	31602464
MMDBr0022722	PG(14:0/14:0)	Glycerol	Cardiolipin synthase A	Synthesis	PathBank	31602464
MMDBr0022755	PG(14:0/14:0)	Ethanolamine	Cardiolipin synthase C	Synthesis	PathBank	31602464
MMDBr0022756	PG(14:0/14:0)	Glycerol	Cardiolipin synthase A	Synthesis	PathBank	31602464
MMDBr0022783	PG(14:0/14:0)	Ethanolamine	Cardiolipin synthase C	Synthesis	PathBank	31602464
MMDBr0022784	PG(14:0/14:0)	Glycerol	Cardiolipin synthase A	Synthesis	PathBank	31602464
MMDBr0022853	PG(14:0/14:0)	Ethanolamine	Cardiolipin synthase C	Synthesis	PathBank	31602464
MMDBr0022854	PG(14:0/14:0)	Glycerol	Cardiolipin synthase A	Synthesis	PathBank	31602464
MMDBr0023044	PG(14:0/14:0)	Ethanolamine	Cardiolipin synthase C	Synthesis	PathBank	31602464
MMDBr0023045	PG(14:0/14:0)	Glycerol	Cardiolipin synthase A	Synthesis	PathBank	31602464
MMDBr0023072	PG(14:0/14:0)	Ethanolamine	Cardiolipin synthase C	Synthesis	PathBank	31602464
MMDBr0023073	PG(14:0/14:0)	Glycerol	Cardiolipin synthase A	Synthesis	PathBank	31602464
MMDBr0023102	PG(14:0/14:0)	Ethanolamine	Cardiolipin synthase C	Synthesis	PathBank	31602464
MMDBr0023103	PG(14:0/14:0)	Glycerol	Cardiolipin synthase A	Synthesis	PathBank	31602464
MMDBr0023204	PG(14:0/14:0)	Ethanolamine	Cardiolipin synthase C	Synthesis	PathBank	31602464
MMDBr0023205	PG(14:0/14:0)	Glycerol	Cardiolipin synthase A	Synthesis	PathBank	31602464
MMDBr0023214	PG(14:0/14:0)	Ethanolamine	Cardiolipin synthase C	Synthesis	PathBank	31602464
MMDBr0023215	PG(14:0/14:0)	Glycerol	Cardiolipin synthase A	Synthesis	PathBank	31602464
MMDBr0023218	PG(14:0/14:0)	Glycerol	Cardiolipin synthase A	Synthesis	PathBank	31602464
MMDBr0023234	PG(14:0/14:0)	Glycerol	Cardiolipin synthase A	Synthesis	PathBank	31602464
MMDBr0023237	PG(14:0/14:0)	Glycerol	Cardiolipin synthase A	Synthesis	PathBank	31602464
MMDBr0023242	PG(14:0/14:0)	Glycerol	Cardiolipin synthase A	Synthesis	PathBank	31602464
MMDBr0023243	PG(14:0/14:0)	Ethanolamine	Cardiolipin synthase C	Synthesis	PathBank	31602464
MMDBr0023244	PG(14:0/14:0)	Glycerol	Cardiolipin synthase A	Synthesis	PathBank	31602464
MMDBr0023247	PG(14:0/14:0)	Glycerol	Cardiolipin synthase A	Synthesis	PathBank	31602464
MMDBr0023250	PG(14:0/14:0)	Glycerol	Cardiolipin synthase A	Synthesis	PathBank	31602464
MMDBr0023251	PG(14:0/14:0)	Glycerol	Cardiolipin synthase A	Synthesis	PathBank	31602464
MMDBr0023253	PG(14:0/14:0)	Glycerol	Cardiolipin synthase A	Synthesis	PathBank	31602464
MMDBr0023258	PG(14:0/14:0)	Ethanolamine	Cardiolipin synthase C	Synthesis	PathBank	31602464
MMDBr0023259	PG(14:0/14:0)	Glycerol	Cardiolipin synthase A	Synthesis	PathBank	31602464
MMDBr0023277	PG(14:0/14:0)	Ethanolamine	Cardiolipin synthase C	Synthesis	PathBank	31602464
MMDBr0023278	PG(14:0/14:0)	Glycerol	Cardiolipin synthase A	Synthesis	PathBank	31602464
MMDBr0023279	PG(14:0/14:0)	Ethanolamine	Cardiolipin synthase C	Synthesis	PathBank	31602464
MMDBr0023280	PG(14:0/14:0)	Glycerol	Cardiolipin synthase A	Synthesis	PathBank	31602464
MMDBr0037582	PG(14:0/14:0)	2-Acyl-sn-glycero-3-phosphoglycerol (N-C14:0)	Not Available		RHEA	34755880

Health Effects and Bioactivity

Health Outcome/Bioactivity	Metabolite Response/Effect	Evidence Type	Host and Biospecimen	Data Source	Reference

Microbial Sources

Superkingdom/Kingdom	Phylum	Total species	Hosts and Body Sites	Microbial Links
Bacteria	Proteobacteria	1	Human ; Human feces; Human feces; pleural fluid plaque; bal; Human stool	Unknown
Eukaryota/Fungi	Ascomycota	1	Human feces; Human saliva	Unknown

Exposure Sources

Source Type	Source Sub-type	Species	Data Source	Reference

Host Biospecimen and Location

Host and Biospecimen	Status	Mean	Std	Min	Max	Units	Age	Sex	Health Condition	Data Source	Reference

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FooDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

Not Available

PDB ID

Not Available

ChEBI ID

60723

Food Biomarker Ontology

Not Available

References

Synthesis Reference

Not Available

General References

Wishart DS, Li C, Marcu A, Badran H, Pon A, Budinski Z, Patron J, Lipton D, Cao X, Oler E, Li K, Paccoud M, Hong C, Guo AC, Chan C, Wei W, Ramirez-Gaona M: PathBank: a comprehensive pathway database for model organisms. Nucleic Acids Res. 2020 Jan 8;48(D1):D470-D478. doi: 10.1093/nar/gkz861. [PubMed:31602464 ]

Showing metabocard for PG(14:0/14:0) (MMDBc0030227)

MOL for #<Metabolite:0x00007fa4ec42cb18>

3D MOL for #<Metabolite:0x00007fa4ec42cb18>

3D SDF for #<Metabolite:0x00007fa4ec42cb18>

3D-SDF for #<Metabolite:0x00007fa4ec42cb18>

PDB for #<Metabolite:0x00007fa4ec42cb18>

3D PDB for #<Metabolite:0x00007fa4ec42cb18>

SMILES for #<Metabolite:0x00007fa4ec42cb18>

INCHI for #<Metabolite:0x00007fa4ec42cb18>

Structure for #<Metabolite:0x00007fa4ec42cb18>

3D Structure for #<Metabolite:0x00007fa4ec42cb18>