Record Information
Version1.0
StatusDetected and Quantified
Creation Date2021-11-18 02:02:48 UTC
Update Date2022-08-31 18:30:37 UTC
Metabolite IDMMDBc0032110
Metabolite Identification
Common Name(S)-2,3,4,5-tetrahydrodipicolinate
Description(S)-2,3,4,5-tetrahydrodipicolinate is an intermediate in L-lysine biosynthesis I pathway in E.coli. It is a substrate for the enzyme tetrahydrodipicolinate succinylase which catalyzes the reaction (S)-2,3,4,5-tetrahydrodipicolinate + succinyl-CoA + H2O -> N-succinyl-2-amino-6-ketopimelate + coenzyme A. It is also a product for enzyme 4-hydroxy-tetrahydrodipicolinate reductase which catalyzes reaction (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NADPH + H+ -> (S)-2,3,4,5-tetrahydrodipicolinate + NADP+ + H2O (BioCyc compound: DELTA1-PIPERIDEINE-2-6-DICARBOXYLATE).
Structure
Synonyms
ValueSource
2,3,4,5-TetrahydrodipicolinateChEBI
2,3,4,5-Tetrahydrodipicolinic acidGenerator
(S)-2,3,4,5-Tetrahydrodipicolinic acidGenerator
2,3,4,5-Tetrahydrodipicolinic acid(2-)Generator
Molecular FormulaC7H7NO4
Average Mass169.137
Monoisotopic Mass169.038604869
IUPAC Name2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
Traditional Name2,3,4,5-tetrahydrodipicolinate
CAS Registry NumberNot Available
SMILES
[O-]C(=O)C1CCCC(=N1)C([O-])=O
InChI Identifier
InChI=1S/C7H9NO4/c9-6(10)4-2-1-3-5(8-4)7(11)12/h4H,1-3H2,(H,9,10)(H,11,12)/p-2
InChI KeyCXMBCXQHOXUCEO-UHFFFAOYSA-L