Record Information
Version1.0
StatusDetected and Quantified
Creation Date2021-11-23 23:18:36 UTC
Update Date2024-04-30 20:33:39 UTC
Metabolite IDMMDBc0047953
Metabolite Identification
Common NameD-Xylulose 1-phosphate
DescriptionD-Xylulose 1-phosphate is produced in the hepatocytes and is the product of fructokinase (ketohexokinase, EC 2.7.1.3) phosphorylation of D-xylulose. The cleavage of D-xylulose-1-phosphate glycolaldehyde by aldolase (fructose-bisphosphate aldolase, EC 4.1.2.13) produces glycolaldehyde which is an oxalate precursor. The distribution of both enzymes in human tissues indicates that this reaction sequence occurs mainly in the liver, to a lesser extent in the kidney, and very little in heart, brain and muscle. The kinetic properties of fructokinase show that this enzyme can phosphorylate D-xylulose as readily as D-fructose (PMID: 6458298 , 13898172 , 6284103 , 2996495 ).
Structure
Synonyms
ValueSource
D-Xylulose 1-phosphoric acidGenerator
L-Threo-pentulose 1-phosphateHMDB
Xylulose-1-phosphateHMDB
D-Xylulose-1-phosphateHMDB
D-Xylulose 1-phosphateHMDB
Molecular FormulaC5H11O8P
Average Mass230.109
Monoisotopic Mass230.019154312
IUPAC Name{[(3S,4R)-3,4,5-trihydroxy-2-oxopentyl]oxy}phosphonic acid
Traditional Name[(3S,4R)-3,4,5-trihydroxy-2-oxopentyl]oxyphosphonic acid
CAS Registry Number63323-91-1
SMILES
OC[C@@H](O)[C@H](O)C(=O)COP(O)(O)=O
InChI Identifier
InChI=1S/C5H11O8P/c6-1-3(7)5(9)4(8)2-13-14(10,11)12/h3,5-7,9H,1-2H2,(H2,10,11,12)/t3-,5+/m1/s1
InChI KeyNBOCCPQHBPGYCX-WUJLRWPWSA-N