Mrv0541 10181222132D
34 36 0 0 0 0 999 V2000
-2.8579 -4.1250 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-3.5724 -2.8875 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-2.1434 -3.7125 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-2.8579 -2.4750 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-6.4302 -3.7125 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-7.1447 -4.1250 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-1.4289 -1.6500 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-0.0000 -1.6500 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-3.5724 -3.7125 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-2.1434 -2.8875 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-0.7145 -1.2375 0.0000 C 0 0 1 0 0 0 0 0 0 0 0 0
-5.7158 -4.1250 0.0000 C 0 0 1 0 0 0 0 0 0 0 0 0
-7.8592 -3.7125 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-0.0000 0.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
0.7145 -0.4125 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-4.2868 -4.1250 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-0.0000 0.8250 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-5.7158 -4.9500 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
1.4289 0.8250 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
2.1434 1.2375 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0
-1.4289 -2.4750 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0
0.7145 -1.2375 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0
-0.7145 -0.4125 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0
-5.0013 -3.7125 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0
1.4289 0.0000 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0
0.7145 1.2375 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0
-8.5737 -4.1250 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
-7.8592 -2.8875 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
-4.2868 -4.9500 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
-0.7145 1.2375 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
-5.0013 -5.3625 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
-6.4302 -5.3625 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
-0.7145 -2.0625 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0
-6.4302 -4.5375 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0
3 1 1 0 0 0 0
4 2 2 0 0 0 0
6 5 1 0 0 0 0
9 1 2 0 0 0 0
9 2 1 0 0 0 0
10 3 2 0 0 0 0
10 4 1 0 0 0 0
11 7 1 6 0 0 0
11 8 1 0 0 0 0
12 5 1 0 0 0 0
13 6 1 0 0 0 0
15 14 2 0 0 0 0
16 9 1 0 0 0 0
17 14 1 0 0 0 0
18 12 1 0 0 0 0
20 19 2 0 0 0 0
21 7 1 0 0 0 0
21 10 1 0 0 0 0
22 8 1 0 0 0 0
22 15 1 0 0 0 0
23 11 1 0 0 0 0
23 14 1 0 0 0 0
12 24 1 1 0 0 0
24 16 1 0 0 0 0
25 15 1 0 0 0 0
25 19 1 0 0 0 0
26 17 2 0 0 0 0
26 19 1 0 0 0 0
27 13 2 0 0 0 0
28 13 1 0 0 0 0
29 16 2 0 0 0 0
30 17 1 0 0 0 0
31 18 2 0 0 0 0
32 18 1 0 0 0 0
11 33 1 1 0 0 0
12 34 1 1 0 0 0
M END
> <DATABASE_ID>
MMDBc0054075
> <DATABASE_NAME>
MIME
> <SMILES>
[H][C@@](CCC(O)=O)(NC(=O)C1=CC=C(NC[C@@]2([H])CNC3=C(N2)C(O)=NC(=N)N3)C=C1)C(O)=O
> <INCHI_IDENTIFIER>
InChI=1S/C19H23N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,11-12,21,23H,5-8H2,(H,24,29)(H,27,28)(H,31,32)(H4,20,22,25,26,30)/t11-,12-/m0/s1
> <INCHI_KEY>
MSTNYGQPCMXVAQ-RYUDHWBXSA-N
> <FORMULA>
C19H23N7O6
> <MOLECULAR_WEIGHT>
445.4292
> <EXACT_MASS>
445.170981503
> <JCHEM_ACCEPTOR_COUNT>
12
> <JCHEM_AVERAGE_POLARIZABILITY>
44.33079846997619
> <JCHEM_BIOAVAILABILITY>
0
> <JCHEM_DONOR_COUNT>
9
> <JCHEM_FORMAL_CHARGE>
0
> <JCHEM_GHOSE_FILTER>
0
> <JCHEM_IUPAC>
(2S)-2-{[4-({[(6S)-4-hydroxy-2-imino-1,2,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido}pentanedioic acid
> <ALOGPS_LOGP>
-1.43
> <JCHEM_LOGP>
-5.333876874585586
> <ALOGPS_LOGS>
-3.32
> <JCHEM_MDDR_LIKE_RULE>
1
> <JCHEM_NUMBER_OF_RINGS>
3
> <JCHEM_PHYSIOLOGICAL_CHARGE>
-1
> <JCHEM_PKA>
3.2149112395459203
> <JCHEM_PKA_STRONGEST_ACIDIC>
-13.082288776416938
> <JCHEM_PKA_STRONGEST_BASIC>
15.000001098672588
> <JCHEM_POLAR_SURFACE_AREA>
208.25999999999996
> <JCHEM_REFRACTIVITY>
132.4011
> <JCHEM_ROTATABLE_BOND_COUNT>
9
> <JCHEM_RULE_OF_FIVE>
0
> <ALOGPS_SOLUBILITY>
2.15e-01 g/l
> <JCHEM_TRADITIONAL_IUPAC>
(2S)-2-{[4-({[(6S)-4-hydroxy-2-imino-5,6,7,8-tetrahydro-1H-pteridin-6-yl]methyl}amino)phenyl]formamido}pentanedioic acid
> <JCHEM_VEBER_RULE>
0
$$$$