MiMeDB: Showing metabocard for dehydroprobetaenone I (MMDBc0055893)

Record Information

Version

1.0

Status

Detected and Quantified

Creation Date

2022-06-17 20:09:57 UTC

Update Date

2022-08-12 20:09:28 UTC

Metabolite ID

MMDBc0055893

Metabolite Identification

Common Name

dehydroprobetaenone I

Description

Dehydroprobetaenone I belongs to the class of organic compounds known as enones. Enones are compounds containing the enone functional group, with the structure RC(=O)CR'. Based on a literature review very few articles have been published on Dehydroprobetaenone I.

Structure

MOL SDF PDB SMILES InChI


  Mrv1652306172222092D          

 31 32  0  0  1  0            999 V2000
    3.5724    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    3.3000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000    3.3000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.8986    3.1070    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724    2.0625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.6771    3.8822    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2074    4.5142    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145    2.0625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0000    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145    1.2375    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    2.8579    2.4750    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   -0.0000    2.4750    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    2.1434    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145    1.2375    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    1.9592    3.1070    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434    2.0625    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.7145    2.0625    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    1.4289    2.4750    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    3.0198    4.3710    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.5527    3.6801    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.8646    4.0255    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.9252    5.2895    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145    0.4125    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724    2.8875    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145    2.8875    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145    0.4125    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    1.6500    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    1.6500    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
  7  1  1  0  0  0  0
  9  8  2  0  0  0  0
 13  2  1  1  0  0  0
 13 10  1  0  0  0  0
 13 11  1  0  0  0  0
 14  3  1  6  0  0  0
 14  7  1  0  0  0  0
 15  4  1  1  0  0  0
 15 10  1  0  0  0  0
 16  5  1  0  0  0  0
 16 12  2  0  0  0  0
 17 11  1  0  0  0  0
 17 12  1  0  0  0  0
 18  8  1  0  0  0  0
 19 14  1  1  0  0  0
 19 16  1  0  0  0  0
 20 15  1  0  0  0  0
 20 17  1  0  0  0  0
 21  6  1  6  0  0  0
 21 18  1  1  0  0  0
 21 19  1  0  0  0  0
 21 20  1  0  0  0  0
 22  9  1  0  0  0  0
 23 18  2  0  0  0  0
 24  8  1  0  0  0  0
 25  9  1  0  0  0  0
 13 26  1  6  0  0  0
 14 27  1  1  0  0  0
 15 28  1  6  0  0  0
 17 29  1  6  0  0  0
 19 30  1  6  0  0  0
 20 31  1  1  0  0  0
M  END


  Mrv1652306172222092D          

 31 32  0  0  1  0            999 V2000
    3.5724    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    3.3000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000    3.3000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.8986    3.1070    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724    2.0625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.6771    3.8822    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2074    4.5142    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145    2.0625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0000    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145    1.2375    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    2.8579    2.4750    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   -0.0000    2.4750    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    2.1434    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145    1.2375    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    1.9592    3.1070    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434    2.0625    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.7145    2.0625    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    1.4289    2.4750    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    3.0198    4.3710    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.5527    3.6801    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.8646    4.0255    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.9252    5.2895    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145    0.4125    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724    2.8875    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145    2.8875    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145    0.4125    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    1.6500    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    1.6500    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
  7  1  1  0  0  0  0
  9  8  2  0  0  0  0
 13  2  1  1  0  0  0
 13 10  1  0  0  0  0
 13 11  1  0  0  0  0
 14  3  1  6  0  0  0
 14  7  1  0  0  0  0
 15  4  1  1  0  0  0
 15 10  1  0  0  0  0
 16  5  1  0  0  0  0
 16 12  2  0  0  0  0
 17 11  1  0  0  0  0
 17 12  1  0  0  0  0
 18  8  1  0  0  0  0
 19 14  1  1  0  0  0
 19 16  1  0  0  0  0
 20 15  1  0  0  0  0
 20 17  1  0  0  0  0
 21  6  1  6  0  0  0
 21 18  1  1  0  0  0
 21 19  1  0  0  0  0
 21 20  1  0  0  0  0
 22  9  1  0  0  0  0
 23 18  2  0  0  0  0
 24  8  1  0  0  0  0
 25  9  1  0  0  0  0
 13 26  1  6  0  0  0
 14 27  1  1  0  0  0
 15 28  1  6  0  0  0
 17 29  1  6  0  0  0
 19 30  1  6  0  0  0
 20 31  1  1  0  0  0
M  END
> <DATABASE_ID>
MMDBc0055893

> <DATABASE_NAME>
MIME

> <SMILES>
[H]\C(O)=C(/[H])C(=O)[C@@]1(C)[C@]([H])(C(C)=C[C@@]2([H])C[C@@]([H])(C)C[C@@]([H])(C)[C@]12[H])[C@]([H])(C)CC

> <INCHI_IDENTIFIER>
InChI=1S/C21H34O2/c1-7-14(3)19-16(5)12-17-11-13(2)10-15(4)20(17)21(19,6)18(23)8-9-22/h8-9,12-15,17,19-20,22H,7,10-11H2,1-6H3/b9-8-/t13-,14+,15+,17+,19-,20-,21-/m0/s1

> <INCHI_KEY>
BINVZINZKJFBTL-QQJLSPJJSA-N

> <FORMULA>
C21H34O2

> <MOLECULAR_WEIGHT>
318.501

> <EXACT_MASS>
318.255880335

> <JCHEM_ACCEPTOR_COUNT>
2

> <JCHEM_ATOM_COUNT>
57

> <JCHEM_AVERAGE_POLARIZABILITY>
38.142265447916365

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
1

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
(2Z)-1-[(1R,2S,4aR,6S,8R,8aS)-2-[(2R)-butan-2-yl]-1,3,6,8-tetramethyl-1,2,4a,5,6,7,8,8a-octahydronaphthalen-1-yl]-3-hydroxyprop-2-en-1-one

> <JCHEM_LOGP>
5.859779814333335

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
2

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA_STRONGEST_ACIDIC>
9.333452760509887

> <JCHEM_PKA_STRONGEST_BASIC>
-5.2773477625529805

> <JCHEM_POLAR_SURFACE_AREA>
37.3

> <JCHEM_REFRACTIVITY>
97.81539999999995

> <JCHEM_ROTATABLE_BOND_COUNT>
4

> <JCHEM_RULE_OF_FIVE>
0

> <JCHEM_TRADITIONAL_IUPAC>
(2Z)-1-[(1R,2S,4aR,6S,8R,8aS)-2-[(2R)-butan-2-yl]-1,3,6,8-tetramethyl-4a,5,6,7,8,8a-hexahydro-2H-naphthalen-1-yl]-3-hydroxyprop-2-en-1-one

> <JCHEM_VEBER_RULE>
1

$$$$

HEADER    PROTEIN                                 17-JUN-22   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   17-JUN-22         0                                  
HETATM    1  C   UNK     0       6.668   2.310   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0      -2.667   1.540   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0       5.335   6.160   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0       0.000   6.160   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0       5.335   1.540   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0       1.677   5.800   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0       6.668   3.850   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0       3.131   7.247   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0       4.120   8.427   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0      -1.334   3.850   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0      -0.000   1.540   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0       2.667   1.540   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0      -1.334   2.310   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0       5.335   4.620   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0      -0.000   4.620   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0       4.001   2.310   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0       1.334   2.310   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0       3.657   5.800   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0       4.001   3.850   0.000  0.00  0.00           C+0
HETATM   20  C   UNK     0       1.334   3.850   0.000  0.00  0.00           C+0
HETATM   21  C   UNK     0       2.667   4.620   0.000  0.00  0.00           C+0
HETATM   22  O   UNK     0       5.637   8.159   0.000  0.00  0.00           O+0
HETATM   23  O   UNK     0       4.765   6.869   0.000  0.00  0.00           O+0
HETATM   24  H   UNK     0       1.614   7.514   0.000  0.00  0.00           H+0
HETATM   25  H   UNK     0       3.594   9.874   0.000  0.00  0.00           H+0
HETATM   26  H   UNK     0      -1.334   0.770   0.000  0.00  0.00           H+0
HETATM   27  H   UNK     0       6.668   5.390   0.000  0.00  0.00           H+0
HETATM   28  H   UNK     0       1.334   5.390   0.000  0.00  0.00           H+0
HETATM   29  H   UNK     0       1.334   0.770   0.000  0.00  0.00           H+0
HETATM   30  H   UNK     0       5.335   3.080   0.000  0.00  0.00           H+0
HETATM   31  H   UNK     0       2.667   3.080   0.000  0.00  0.00           H+0
CONECT    1    7                                                            
CONECT    2   13                                                            
CONECT    3   14                                                            
CONECT    4   15                                                            
CONECT    5   16                                                            
CONECT    6   21                                                            
CONECT    7    1   14                                                       
CONECT    8    9   18   24                                                  
CONECT    9    8   22   25                                                  
CONECT   10   13   15                                                       
CONECT   11   13   17                                                       
CONECT   12   16   17                                                       
CONECT   13    2   10   11   26                                             
CONECT   14    3    7   19   27                                             
CONECT   15    4   10   20   28                                             
CONECT   16    5   12   19                                                  
CONECT   17   11   12   20   29                                             
CONECT   18    8   21   23                                                  
CONECT   19   14   16   21   30                                             
CONECT   20   15   17   21   31                                             
CONECT   21    6   18   19   20                                             
CONECT   22    9                                                            
CONECT   23   18                                                            
CONECT   24    8                                                            
CONECT   25    9                                                            
CONECT   26   13                                                            
CONECT   27   14                                                            
CONECT   28   15                                                            
CONECT   29   17                                                            
CONECT   30   19                                                            
CONECT   31   20                                                            
MASTER        0    0    0    0    0    0    0    0   31    0   64    0
END

Synonyms

Not Available

Molecular Formula

C₂₁H₃₄O₂

Average Mass

318.501

Monoisotopic Mass

318.255880335

IUPAC Name

(2Z)-1-[(1R,2S,4aR,6S,8R,8aS)-2-[(2R)-butan-2-yl]-1,3,6,8-tetramethyl-1,2,4a,5,6,7,8,8a-octahydronaphthalen-1-yl]-3-hydroxyprop-2-en-1-one

Traditional Name

(2Z)-1-[(1R,2S,4aR,6S,8R,8aS)-2-[(2R)-butan-2-yl]-1,3,6,8-tetramethyl-4a,5,6,7,8,8a-hexahydro-2H-naphthalen-1-yl]-3-hydroxyprop-2-en-1-one

CAS Registry Number

Not Available

SMILES

[H]\C(O)=C(/[H])C(=O)[C@@]1(C)[C@]([H])(C(C)=C[C@@]2([H])C[C@@]([H])(C)C[C@@]([H])(C)[C@]12[H])[C@]([H])(C)CC

InChI Identifier

InChI=1S/C21H34O2/c1-7-14(3)19-16(5)12-17-11-13(2)10-15(4)20(17)21(19,6)18(23)8-9-22/h8-9,12-15,17,19-20,22H,7,10-11H2,1-6H3/b9-8-/t13-,14+,15+,17+,19-,20-,21-/m0/s1

InChI Key

BINVZINZKJFBTL-QQJLSPJJSA-N

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as enones. Enones are compounds containing the enone functional group, with the structure RC(=O)CR'.

Kingdom

Organic compounds

Super Class

Organic oxygen compounds

Class

Organooxygen compounds

Sub Class

Carbonyl compounds

Direct Parent

Enones

Alternative Parents

Substituents

Vinylogous acid
Enone
Acryloyl-group
Ketone
Enol
Organic oxide
Hydrocarbon derivative
Aliphatic homopolycyclic compound

Molecular Framework

Aliphatic homopolycyclic compounds

External Descriptors

Not Available

Functional Ontology

Not Available

Physical Properties

State

Expected Solid

Predicted Properties

Property	Value	Source
logP	5.86	ChemAxon
pKa (Strongest Acidic)	9.33	ChemAxon
pKa (Strongest Basic)	-5.3	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	2	ChemAxon
Hydrogen Donor Count	1	ChemAxon
Polar Surface Area	37.3 Å²	ChemAxon
Rotatable Bond Count	4	ChemAxon
Refractivity	97.82 m³·mol⁻¹	ChemAxon
Polarizability	38.14 Å³	ChemAxon
Number of Rings	2	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	Yes	ChemAxon
MDDR-like Rule	No	ChemAxon

Spectra

Spectrum Type	Description	Splash Key	Deposition Date	View
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (TMS_1_1) - 70eV, Positive	Not Available	2022-08-08	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 10V, Positive	Not Available	2022-08-10	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 20V, Positive	Not Available	2022-08-10	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 40V, Positive	Not Available	2022-08-10	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 10V, Negative	Not Available	2022-08-10	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 20V, Negative	Not Available	2022-08-10	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 40V, Negative	Not Available	2022-08-10	View Spectrum
MS	Mass Spectrum (Electron Ionization)	Not Available	2022-08-06	View Spectrum

Biological Properties

Cellular Locations

Not Available

Biospecimen Locations

Not Available

Tissue Locations

Not Available

Associated OMIM IDs

114500 (Colorectal cancer)
610247 (Eosinophilic esophagitis)

Human Proteins and Enzymes

Protein ID	Protein Name	Protein Type	Uniprot ID	Species

Human Pathways

Pathways

Name	SMPDB/PathBank

Metabolic Reactions

Reaction ID	Precursor	Product	Enzyme	Reaction Type	Data Source	Reference
MMDBr0017144	dehydroprobetaenone I	Betaenone C	Cytochrome P450 monooxygenase bet2	Oxygenation	RHEA	34755880
MMDBr0017145	dehydroprobetaenone I	Betaenone C	Cytochrome P450 monooxygenase bet2	Oxygenation	RHEA	34755880
MMDBr0017146	dehydroprobetaenone I	epoxybetaenone	Cytochrome P450 monooxygenase bet2	Oxygenation	RHEA	34755880
MMDBr0017147	dehydroprobetaenone I	epoxybetaenone	Cytochrome P450 monooxygenase bet2	Oxygenation	RHEA	34755880
MMDBr0025390	Hydrogen Ion	Water	Trans-enoyl reductase bet3	Reduction; Synthesis	RHEA	34755880
MMDBr0025391	Hydrogen Ion	Water	Trans-enoyl reductase bet3	Reduction; Synthesis	RHEA	34755880
MMDBr0025761	dehydroprobetaenone I	probetaenone I	Short-chain dehydrogenase/reductase bet4	Dehydrogenation; Reduction	RHEA	34755880
MMDBr0025762	dehydroprobetaenone I	probetaenone I	Short-chain dehydrogenase/reductase bet4	Dehydrogenation; Reduction	RHEA	34755880

Health Effects and Bioactivity

Health Outcome/Bioactivity	Metabolite Response/Effect	Evidence Type	Host and Biospecimen	Data Source	Reference

Microbial Sources

Superkingdom/Kingdom	Phylum	Total species	Hosts and Body Sites	Microbial Links
Eukaryota/Fungi	Ascomycota	2

Exposure Sources

Source Type	Source Sub-type	Species	Data Source	Reference

Host Biospecimen and Location

Host and Biospecimen	Status	Mean	Std	Min	Max	Units	Age	Sex	Health Condition	Data Source	Reference

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FooDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

139291715

PDB ID

Not Available

ChEBI ID

Not Available

Food Biomarker Ontology

Not Available

References

Synthesis Reference

Not Available

General References

Bansal P, Morgat A, Axelsen KB, Muthukrishnan V, Coudert E, Aimo L, Hyka-Nouspikel N, Gasteiger E, Kerhornou A, Neto TB, Pozzato M, Blatter MC, Ignatchenko A, Redaschi N, Bridge A: Rhea, the reaction knowledgebase in 2022. Nucleic Acids Res. 2022 Jan 7;50(D1):D693-D700. doi: 10.1093/nar/gkab1016. [PubMed:34755880 ]

Showing metabocard for dehydroprobetaenone I (MMDBc0055893)

MOL for #<Metabolite:0x00007fd0c41c3008>

3D MOL for #<Metabolite:0x00007fd0c41c3008>

3D SDF for #<Metabolite:0x00007fd0c41c3008>

3D-SDF for #<Metabolite:0x00007fd0c41c3008>

PDB for #<Metabolite:0x00007fd0c41c3008>

3D PDB for #<Metabolite:0x00007fd0c41c3008>

SMILES for #<Metabolite:0x00007fd0c41c3008>

INCHI for #<Metabolite:0x00007fd0c41c3008>

Structure for #<Metabolite:0x00007fd0c41c3008>

3D Structure for #<Metabolite:0x00007fd0c41c3008>