Showing metabocard for trans-Cinnamic acid (MMDBc0029516)

Record Information
Version1.0
StatusDetected and Quantified
Creation Date2021-11-17 23:25:32 UTC
Update Date2024-09-27 19:40:29 UTC
Metabolite IDMMDBc0029516
Metabolite Identification
Common Nametrans-Cinnamic acid
DescriptionCinnamic acid has the formula C6H5CHCHCOOH and is an odorless white crystalline acid, which is slightly soluble in water. It has a melting point of 133 degrees and a boiling point of 300 degrees. Cinnamic acid has a honey-like odor and its more volatile ethyl ester (ethyl cinnamate) are flavor components in the essential oil of cinnamon. It is involved in E. coli's aromatic compound metabolism and 3-phenylpropanoate degradation. Cinnamic acid is also part of the biosynthetic shikimate and phenylpropanoid pathways. Its biosynthesis is performed by the action of the enzyme phenylalanine ammonia-lyase (PAL) on phenylalanine.
Structure
MOL3D MOLSDF3D SDFPDB3D PDBSMILESInChI

MOL for #<Metabolite:0x00007f46a286e418>


  Mrv1652309272007382D          

 11 11  0  0  0  0            999 V2000
   -0.8703    0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5847    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2993    0.4124    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2993   -0.4124    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5848   -0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8703   -0.4124    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1558    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5586    0.4124    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.2731    0.8249    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.2731    1.6499    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.9876    0.4124    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  2  0  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
  4  5  1  0  0  0  0
  5  6  2  0  0  0  0
  6  1  1  0  0  0  0
  1  7  1  0  0  0  0
  7  8  2  0  0  0  0
  8  9  1  0  0  0  0
  9 10  2  0  0  0  0
  9 11  1  0  0  0  0
M  END
Download

3D MOL for #<Metabolite:0x00007f46a286e418>

HMDB0000930
     RDKit          3D
trans-Cinnamic acid
 19 19  0  0  0  0  0  0  0  0999 V2000
    4.3195   -1.0333    0.2016 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.4291   -0.2120   -0.1108 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.8206    0.9754   -0.6940 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.0091   -0.5317    0.1493 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0684    0.3242   -0.1752 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3506    0.1041    0.0385 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7977   -1.0648    0.6175 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1615   -1.2113    0.7926 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.0620   -0.2449    0.4136 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.6247    0.9256   -0.1654 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2701    1.0695   -0.3386 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.4091    1.8639   -0.5399 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.7489   -1.4660    0.6045 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.3700    1.2833   -0.6451 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1159   -1.8739    0.9406 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4935   -2.1519    1.2564 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.1224   -0.4403    0.5876 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3136    1.6979   -0.4708 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8626    1.9862   -0.7971 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  2  0
  2  3  1  0
  2  4  1  0
  4  5  2  0
  5  6  1  0
  6  7  2  0
  7  8  1  0
  8  9  2  0
  9 10  1  0
 10 11  2  0
 11  6  1  0
  3 12  1  0
  4 13  1  0
  5 14  1  0
  7 15  1  0
  8 16  1  0
  9 17  1  0
 10 18  1  0
 11 19  1  0
M  END
Download

3D SDF for #<Metabolite:0x00007f46a286e418>


  Mrv1652309272007382D          

 11 11  0  0  0  0            999 V2000
   -0.8703    0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5847    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2993    0.4124    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2993   -0.4124    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5848   -0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8703   -0.4124    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1558    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5586    0.4124    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.2731    0.8249    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.2731    1.6499    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.9876    0.4124    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  2  0  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
  4  5  1  0  0  0  0
  5  6  2  0  0  0  0
  6  1  1  0  0  0  0
  1  7  1  0  0  0  0
  7  8  2  0  0  0  0
  8  9  1  0  0  0  0
  9 10  2  0  0  0  0
  9 11  1  0  0  0  0
M  END
> <DATABASE_ID>
MMDBc0029516

> <DATABASE_NAME>
MIME

> <SMILES>
OC(=O)\C=C\C1=CC=CC=C1

> <INCHI_IDENTIFIER>
InChI=1S/C9H8O2/c10-9(11)7-6-8-4-2-1-3-5-8/h1-7H,(H,10,11)/b7-6+

> <INCHI_KEY>
WBYWAXJHAXSJNI-VOTSOKGWSA-N

> <FORMULA>
C9H8O2

> <MOLECULAR_WEIGHT>
148.1586

> <EXACT_MASS>
148.0524295

> <JCHEM_ACCEPTOR_COUNT>
2

> <JCHEM_ATOM_COUNT>
19

> <JCHEM_AVERAGE_POLARIZABILITY>
15.428464888087186

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
1

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
(2E)-3-phenylprop-2-enoic acid

> <ALOGPS_LOGP>
2.38

> <JCHEM_LOGP>
2.13608626

> <ALOGPS_LOGS>
-2.38

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
1

> <JCHEM_PHYSIOLOGICAL_CHARGE>
-1

> <JCHEM_PKA_STRONGEST_ACIDIC>
4.509231934706283

> <JCHEM_POLAR_SURFACE_AREA>
37.3

> <JCHEM_REFRACTIVITY>
43.0599

> <JCHEM_ROTATABLE_BOND_COUNT>
2

> <JCHEM_RULE_OF_FIVE>
1

> <ALOGPS_SOLUBILITY>
6.18e-01 g/l

> <JCHEM_TRADITIONAL_IUPAC>
cinnamic acid

> <JCHEM_VEBER_RULE>
1

$$$$
Download

3D-SDF for #<Metabolite:0x00007f46a286e418>

HMDB0000930
     RDKit          3D
trans-Cinnamic acid
 19 19  0  0  0  0  0  0  0  0999 V2000
    4.3195   -1.0333    0.2016 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.4291   -0.2120   -0.1108 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.8206    0.9754   -0.6940 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.0091   -0.5317    0.1493 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0684    0.3242   -0.1752 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3506    0.1041    0.0385 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7977   -1.0648    0.6175 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1615   -1.2113    0.7926 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.0620   -0.2449    0.4136 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.6247    0.9256   -0.1654 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2701    1.0695   -0.3386 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.4091    1.8639   -0.5399 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.7489   -1.4660    0.6045 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.3700    1.2833   -0.6451 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1159   -1.8739    0.9406 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4935   -2.1519    1.2564 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.1224   -0.4403    0.5876 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3136    1.6979   -0.4708 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8626    1.9862   -0.7971 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  2  0
  2  3  1  0
  2  4  1  0
  4  5  2  0
  5  6  1  0
  6  7  2  0
  7  8  1  0
  8  9  2  0
  9 10  1  0
 10 11  2  0
 11  6  1  0
  3 12  1  0
  4 13  1  0
  5 14  1  0
  7 15  1  0
  8 16  1  0
  9 17  1  0
 10 18  1  0
 11 19  1  0
M  END
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PDB for #<Metabolite:0x00007f46a286e418>

HEADER    PROTEIN                                 27-SEP-20   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   27-SEP-20         0                                  
HETATM    1  C   UNK     0      -1.625   0.770   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0      -2.958   1.540   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0      -4.292   0.770   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0      -4.292  -0.770   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0      -2.958  -1.540   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0      -1.625  -0.770   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0      -0.291   1.540   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0       1.043   0.770   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0       2.376   1.540   0.000  0.00  0.00           C+0
HETATM   10  O   UNK     0       2.376   3.080   0.000  0.00  0.00           O+0
HETATM   11  O   UNK     0       3.710   0.770   0.000  0.00  0.00           O+0
CONECT    1    2    6    7                                                  
CONECT    2    1    3                                                       
CONECT    3    2    4                                                       
CONECT    4    3    5                                                       
CONECT    5    4    6                                                       
CONECT    6    5    1                                                       
CONECT    7    1    8                                                       
CONECT    8    7    9                                                       
CONECT    9    8   10   11                                                  
CONECT   10    9                                                            
CONECT   11    9                                                            
MASTER        0    0    0    0    0    0    0    0   11    0   22    0
END
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3D PDB for #<Metabolite:0x00007f46a286e418>

COMPND    HMDB0000930
HETATM    1  O1  UNL     1       4.319  -1.033   0.202  1.00  0.00           O  
HETATM    2  C1  UNL     1       3.429  -0.212  -0.111  1.00  0.00           C  
HETATM    3  O2  UNL     1       3.821   0.975  -0.694  1.00  0.00           O  
HETATM    4  C2  UNL     1       2.009  -0.532   0.149  1.00  0.00           C  
HETATM    5  C3  UNL     1       1.068   0.324  -0.175  1.00  0.00           C  
HETATM    6  C4  UNL     1      -0.351   0.104   0.039  1.00  0.00           C  
HETATM    7  C5  UNL     1      -0.798  -1.065   0.617  1.00  0.00           C  
HETATM    8  C6  UNL     1      -2.161  -1.211   0.793  1.00  0.00           C  
HETATM    9  C7  UNL     1      -3.062  -0.245   0.414  1.00  0.00           C  
HETATM   10  C8  UNL     1      -2.625   0.926  -0.165  1.00  0.00           C  
HETATM   11  C9  UNL     1      -1.270   1.070  -0.339  1.00  0.00           C  
HETATM   12  H1  UNL     1       3.409   1.864  -0.540  1.00  0.00           H  
HETATM   13  H2  UNL     1       1.749  -1.466   0.605  1.00  0.00           H  
HETATM   14  H3  UNL     1       1.370   1.283  -0.645  1.00  0.00           H  
HETATM   15  H4  UNL     1      -0.116  -1.874   0.941  1.00  0.00           H  
HETATM   16  H5  UNL     1      -2.494  -2.152   1.256  1.00  0.00           H  
HETATM   17  H6  UNL     1      -4.122  -0.440   0.588  1.00  0.00           H  
HETATM   18  H7  UNL     1      -3.314   1.698  -0.471  1.00  0.00           H  
HETATM   19  H8  UNL     1      -0.863   1.986  -0.797  1.00  0.00           H  
CONECT    1    2    2
CONECT    2    3    4
CONECT    3   12
CONECT    4    5    5   13
CONECT    5    6   14
CONECT    6    7    7   11
CONECT    7    8   15
CONECT    8    9    9   16
CONECT    9   10   17
CONECT   10   11   11   18
CONECT   11   19
END
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SMILES for #<Metabolite:0x00007f46a286e418>

OC(=O)\C=C\C1=CC=CC=C1
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INCHI for #<Metabolite:0x00007f46a286e418>

InChI=1S/C9H8O2/c10-9(11)7-6-8-4-2-1-3-5-8/h1-7H,(H,10,11)/b7-6+
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Synonyms
ValueSource
(2E)-3-Phenyl-2-propenoic acidChEBI
(2E)-3-Phenylacrylic acidChEBI
(e)-3-Phenyl-2-propenoic acidChEBI
(e)-CinnamateChEBI
(e)-Cinnamic acidChEBI
Benzeneacrylic acidChEBI
PHENYLETHYLENECARBOXYLIC ACIDChEBI
trans-3-Phenylacrylic acidChEBI
trans-beta-CarboxystyreneChEBI
trans-CinnamateChEBI
trans-ZimtsaeureChEBI
(2E)-3-Phenyl-2-propenoateGenerator
(2E)-3-PhenylacrylateGenerator
(e)-3-Phenyl-2-propenoateGenerator
BenzeneacrylateGenerator
PHENYLETHYLENECARBOXYLateGenerator
trans-3-PhenylacrylateGenerator
trans-b-CarboxystyreneGenerator
trans-Β-carboxystyreneGenerator
(2E)-2-Phenyl-2-propenoateHMDB
(2E)-2-Phenyl-2-propenoic acidHMDB
(e)-3-PhenylacrylateHMDB
(e)-3-Phenylacrylic acidHMDB
(e)-3-Phenylprop-2-enoateHMDB
(e)-3-Phenylprop-2-enoic acidHMDB
trans-3-Phenyl-2-propenoateHMDB
trans-3-Phenyl-2-propenoic acidHMDB
Cinnamic acid, 14C-labeled CPDHMDB
Cinnamic acid, 2-(14)C-labeled CPDHMDB
Cinnamic acid, 3-(14)C-labeled CPDHMDB
Cinnamic acid, (Z)-isomerHMDB
Cinnamic acid, 2-(13)C-labeled CPDHMDB
Cinnamic acid, 3H-labeled CPD (e)-isomerHMDB
Cinnamic acid, 3H-labeled CPD (Z)-isomerHMDB
Cinnamic acid, ion(1-)-(e)-isomerHMDB
Cinnamic acid, sodium saltHMDB
Cinnamic acid, sodium salt(e)-isomerHMDB
Cinnamic acid, sodium salt(Z)-isomerHMDB
Cinnamic acid, (trans)-(e)-isomerHMDB
Cinnamic acid, 14C-labeled CPD (e)-isomerHMDB
Cinnamic acid, ion(1-)HMDB
Cinnamic acid, nickel (+2) saltHMDB
Cinnamic acid, potassium saltHMDB
Cinnamic acid, zinc salt(e)-isomerHMDB
Cinnamic acid, 13C-labeled CPDHMDB
Cinnamic acidHMDB
(2E)-3-Phenylprop-2-enoic acidHMDB
(2E)-Cinnamic acidHMDB
3-Phenyl-(e)-2-propenoic acidHMDB
3-Phenyl-2-propenoic acidHMDB
3-Phenylacrylic acidHMDB
Phenylacrylic acidHMDB
beta-Phenylacrylic acidHMDB
Β-phenylacrylic acidHMDB
trans-Cinnamic acidHMDB
Molecular FormulaC9H8O2
Average Mass148.1586
Monoisotopic Mass148.0524295
IUPAC Name(2E)-3-phenylprop-2-enoic acid
Traditional Namecinnamic acid
CAS Registry Number140-10-3
SMILES
OC(=O)\C=C\C1=CC=CC=C1
InChI Identifier
InChI=1S/C9H8O2/c10-9(11)7-6-8-4-2-1-3-5-8/h1-7H,(H,10,11)/b7-6+
InChI KeyWBYWAXJHAXSJNI-VOTSOKGWSA-N