MMDBr0013107 | dibenzothiophene 5,5-dioxide | 2'-hydroxybiphenyl-2-sulfinate | Dibenzothiophene desulfurization enzyme A | | RHEA | 34755880 |
MMDBr0013372 | Oxygen | Delta 8,14 -Sterol | Lanosterol 14-alpha demethylase | Demethylation | RHEA | 34755880 |
MMDBr0013373 | Oxygen | Delta 8,14 -Sterol | Lanosterol 14-alpha demethylase | Demethylation | RHEA | 34755880 |
MMDBr0013617 | FMNH2 | (Z)-2-((N-methylformamido)methylene)-5-hydroxybutanolactone | Flavin-dependent trigonelline monooxygenase, oxygenase component | Oxygenation | RHEA | 34755880 |
MMDBr0013618 | FMNH2 | (Z)-2-((N-methylformamido)methylene)-5-hydroxybutanolactone | Flavin-dependent trigonelline monooxygenase, oxygenase component | Oxygenation | RHEA | 34755880 |
MMDBr0013714 | Benzoic acid | 4-Hydroxybenzoic acid | Benzoate 4-monooxygenase bphA | Oxygenation | RHEA | 34755880 |
MMDBr0014122 | FMNH2 | Flavin mononucleotide | NAD(P)H-dependent FMN reductase atnL | Reduction | RHEA | 34755880 |
MMDBr0014123 | Flavin mononucleotide | FMNH2 | Flavin-dependent trigonelline monooxygenase, reductase component | Reduction | RHEA | 34755880 |
MMDBr0014124 | FMNH2 | Flavin mononucleotide | NAD(P)H-dependent FMN reductase atnL | Redox reaction; Reduction | RHEA | 34755880 |
MMDBr0014142 | heme b | biliverdin IXalpha | Heme-degrading monooxygenase | Oxygenation | RHEA | 34755880 |
MMDBr0014538 | Oxygen | (S)-2,3-epoxysqualene | Squalene monooxygenase | Oxygenation | RHEA | 34755880 |
MMDBr0014539 | Oxygen | (S)-2,3-epoxysqualene | Squalene epoxidase ERG1 | Oxidation | RHEA | 34755880 |
MMDBr0014540 | Lanosterin | 4,4-Dimethylcholesta-8,14,24-trienol | Lanosterol 14-alpha demethylase | Demethylation | RHEA | 34755880 |
MMDBr0014541 | Lanosterin | 4,4-Dimethylcholesta-8,14,24-trienol | Lanosterol 14-alpha demethylase | Demethylation | RHEA | 34755880 |
MMDBr0014552 | 2-Amino-2-deoxyisochorismate | 3-(1-carboxyvinyloxy)anthranilate | 2-amino-4-deoxychorismate dehydrogenase | Dehydrogenation | RHEA | 34755880 |
MMDBr0014669 | FMNH2 | 5,6-Dimethylbenzimidazole | 5,6-dimethylbenzimidazole synthase | Synthesis | RHEA | 34755880 |
MMDBr0014927 | monacolin L carboxylic acid | Hydrogen Ion | Dihydromonacolin L monooxygenase LovA | Oxygenation | RHEA | 34755880 |
MMDBr0015040 | FMNH2 | ammoniodiacetic acid | Nitrilotriacetate monooxygenase component A | Oxygenation | RHEA | 34755880 |
MMDBr0015055 | FMNH2 | (Z)-3-Ureidoacrylate | Pyrimidine monooxygenase RutA | Oxygenation | RHEA | 34755880 |
MMDBr0015056 | FMNH2 | (Z)-2-methylureidoacrylic acid | Pyrimidine monooxygenase RutA | Oxygenation | RHEA | 34755880 |
MMDBr0015075 | 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione | 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione | Flavin-dependent monooxygenase, oxygenase subunit HsaA | Oxygenation | RHEA | 34755880 |
MMDBr0015076 | 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione | 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione | Flavin-dependent monooxygenase, oxygenase subunit HsaA | Oxygenation | RHEA | 34755880 |
MMDBr0015143 | ent-kaur-16-ene | ent-kaur-16-en-19-oic acid | Ent-kaurene oxidase P450-4 | Oxidation | RHEA | 34755880 |
MMDBr0015165 | 3,7-Dimethyl-1,6-octadien-3-ol | (6E)-8-oxolinalool | Linalool 8-monooxygenase | Oxygenation | RHEA | 34755880 |
MMDBr0015181 | Eucalyptol | 2-endo-hydroxy-1,8-cineole | 1,8-cineole 2-endo-monooxygenase | Oxygenation | RHEA | 34755880 |
MMDBr0015342 | (1R,4R)-bornane-2,5-dione | (1R,4R)-5-oxo-1,2-campholide | 2,5-diketocamphane 1,2-monooxygenase 1 | Oxygenation | RHEA | 34755880 |
MMDBr0015414 | (1'S)-averantin | (1'S,5'S)-5'-hydroxyaverantin | Averantin hydroxylase | Hydroxylation | RHEA | 34755880 |
MMDBr0015415 | (1'S)-averantin | (1'S,5'R)-5'-hydroxyaverantin | Averantin hydroxylase | Hydroxylation | RHEA | 34755880 |
MMDBr0015439 | O-methylsterigmatocystin | Aflatoxin B1 | O-methylsterigmatocystin oxidoreductase | Redox reaction | RHEA | 34755880 |
MMDBr0015440 | 8-O-methyldihydrosterigmatocystin | Aflatoxin b2 | O-methylsterigmatocystin oxidoreductase | Redox reaction | RHEA | 34755880 |
MMDBr0015462 | Oxygen | 6-hydroxytryprostatin | Tryprostatin B 6-hydroxylase | Hydroxylation | RHEA | 34755880 |
MMDBr0015463 | Oxygen | Fumitremorgin C | Fumitremorgin C synthase | Synthesis | RHEA | 34755880 |
MMDBr0015464 | Fumitremorgin C | 12alpha,13alpha-dihydroxyfumitremorgin C | Fumitremorgin C monooxygenase | Oxygenation | RHEA | 34755880 |
MMDBr0015581 | dimethylallyl phosphate | Phosphate | Flavin prenyltransferase LpdB | Synthesis; Reverse C-prenylation of phenalenone | RHEA | 34755880 |
MMDBr0015734 | hexadecanoic acid | 16-Hydroxy hexadecanoic acid | Cytochrome P450 52-E3 | Hydroxylation | RHEA | 34755880 |
MMDBr0015816 | (9Z)-octadecenoic acid | 18-hydroxy-(9Z)-octadecenoic acid | Cytochrome P450 52-E3 | Hydroxylation | RHEA | 34755880 |
MMDBr0015849 | dihydromonacolin L carboxylic acid | Hydrogen Ion | Dihydromonacolin L monooxygenase LovA | Oxygenation | RHEA | 34755880 |
MMDBr0015916 | 1-Hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate | 2-C-Methyl-D-erythritol-2,4-cyclodiphosphate | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin) | Synthesis | RHEA | 34755880 |
MMDBr0016002 | CoA | Acetyl-CoA | Pyruvate-flavodoxin oxidoreductase | Redox reaction | RHEA | 34755880 |
MMDBr0016201 | 24,25-dihydrolanosterol | 4,4-Dimethyl-5Alpha-Cholesta-8,14-Dien-3Beta-Ol | Lanosterol 14-alpha demethylase | Demethylation | RHEA | 34755880 |
MMDBr0016202 | 24,25-dihydrolanosterol | 4,4-Dimethyl-5Alpha-Cholesta-8,14-Dien-3Beta-Ol | Lanosterol 14-alpha demethylase | Demethylation | RHEA | 34755880 |
MMDBr0016212 | 3,17-dihydroxy-9,10-secoandrost-1,3,5(10)-triene-9-one | 3,4,17-trihydroxy-9,10-secoandrost-1,3,5(10)-triene-9-one | Flavin-dependent monooxygenase, oxygenase subunit HsaA | Oxygenation | RHEA | 34755880 |
MMDBr0016213 | 3,17-dihydroxy-9,10-secoandrost-1,3,5(10)-triene-9-one | 3,4,17-trihydroxy-9,10-secoandrost-1,3,5(10)-triene-9-one | Flavin-dependent monooxygenase, oxygenase subunit HsaA | Oxygenation | RHEA | 34755880 |
MMDBr0016247 | Oxygen | 18-hydroxyoctadecanoic acid | Cytochrome P450 52-M1 | Hydroxylation | RHEA | 34755880 |
MMDBr0016421 | dibenzothiophene | dibenzothiophene 5,5-dioxide | Dibenzothiophene desulfurization enzyme C | | RHEA | 34755880 |
MMDBr0016422 | dibenzothiophene | dibenzothiophene 5-oxide | Dibenzothiophene desulfurization enzyme C | | RHEA | 34755880 |
MMDBr0016423 | dibenzothiophene 5-oxide | dibenzothiophene 5,5-dioxide | Dibenzothiophene desulfurization enzyme C | | RHEA | 34755880 |
MMDBr0016481 | Isobutylamine | Flavin mononucleotide | Isobutylamine N-hydroxylase | Hydroxylation | RHEA | 34755880 |
MMDBr0016521 | Dimethyl sulfone | Flavin mononucleotide | FMNH(2)-dependent dimethylsulfone monooxygenase | Oxygenation | RHEA | 34755880 |
MMDBr0016522 | NADP(+) | Hydrogen Ion | Flavodoxin/ferredoxin--NADP reductase | Reduction | RHEA | 34755880 |
MMDBr0016586 | L-Arginine | Hydrogen Ion | Nitric oxide synthase oxygenase | Oxygenation | RHEA | 34755880 |
MMDBr0016654 | 2-phenylacetic acid | (2-hydroxyphenyl)acetic acid | Phenylacetate 2-hydroxylase | Hydroxylation | RHEA | 34755880 |
MMDBr0016832 | (1S,4S)-bornane-2,5-dione | (1S,4S)-5-oxo-1,2-campholide | 3,6-diketocamphane 1,6-monooxygenase | Oxygenation | RHEA | 34755880 |
MMDBr0016902 | dihydro-ML-236C carboxylic acid | Hydrogen Ion | Dihydro-ML-236C monooxygenase mlcC | Oxygenation | RHEA | 34755880 |
MMDBr0016903 | ML-236C carboxylic acid | Hydrogen Ion | Dihydro-ML-236C monooxygenase mlcC | Oxygenation | RHEA | 34755880 |
MMDBr0017025 | p-Hydroxyphenylacetic acid | 3,4-Dihydroxybenzeneacetic acid | p-hydroxyphenylacetate 3-hydroxylase, oxygenase component | Hydroxylation | RHEA | 34755880 |
MMDBr0017057 | Flavin mononucleotide | dehydro coenzyme F420-0 | Bifunctional F420 biosynthesis protein FbiB | Synthesis | RHEA | 34755880 |
MMDBr0017088 | (9Z,12Z)-octadecadienoic acid | 18-hydroxy-(9Z,12Z)-octadecadienoic acid | Cytochrome P450 52-M1 | Hydroxylation | RHEA | 34755880 |
MMDBr0017091 | (9Z)-octadecenoic acid | 17-hydroxy-(9Z)-octadecenoic acid | Cytochrome P450 52-M1 | Hydroxylation | RHEA | 34755880 |
MMDBr0017092 | (9Z,12Z)-octadecadienoic acid | 17-hydroxy-(9Z,12Z)-octadecadienoic acid | Cytochrome P450 52-M1 | Hydroxylation | RHEA | 34755880 |
MMDBr0017093 | (9Z)-hexadecenoic acid | (9Z)-16-hydroxyhexadec-9-enoic acid | Cytochrome P450 52-E3 | Hydroxylation | RHEA | 34755880 |
MMDBr0017182 | m-Cresol | 3-hydroxybenzyl alcohol | Cytochrome P450 monooxygenase acuC | Oxygenation | RHEA | 34755880 |
MMDBr0017183 | m-Cresol | 3-hydroxybenzyl alcohol | Cytochrome P450 monooxygenase acuC | Oxygenation | RHEA | 34755880 |
MMDBr0017184 | 3-hydroxybenzyl alcohol | gentisyl alcohol | Cytochrome P450 monooxygenase acuD | Oxygenation | RHEA | 34755880 |
MMDBr0017185 | 3-hydroxybenzyl alcohol | gentisyl alcohol | Cytochrome P450 monooxygenase acuD | Oxygenation | RHEA | 34755880 |
MMDBr0017391 | nataloe emodin | Cladofulvin | Cytochrome P450 monooxygenase claM | Oxygenation | RHEA | 34755880 |
MMDBr0017392 | nataloe emodin | Cladofulvin | Cytochrome P450 monooxygenase claM | Oxygenation | RHEA | 34755880 |
MMDBr0017422 | (3E,5S)-3-[(2E,4E,8S,10E,12Z)-1-hydroxy-4,8-dimethyltetradeca-2,4,10,12-tetraen-1-ylidene]-5-[(4-hydroxyphenyl)methyl]pyrrolidine-2,4-dione | 3-[(2E,4E,8S,10E,12Z)-4,8-dimethyltetradeca-2,4,10,12-tetraenoyl]-4-hydroxy-5-(4-hydroxyphenyl)-1,2-dihydropyridin-2-one | Cytochrome P450 monooxygenase iccC | Oxygenation | RHEA | 34755880 |
MMDBr0017423 | (3E,5S)-3-[(2E,4E,8S,10E,12Z)-1-hydroxy-4,8-dimethyltetradeca-2,4,10,12-tetraen-1-ylidene]-5-[(4-hydroxyphenyl)methyl]pyrrolidine-2,4-dione | 3-[(2E,4E,8S,10E,12Z)-4,8-dimethyltetradeca-2,4,10,12-tetraenoyl]-4-hydroxy-5-(4-hydroxyphenyl)-1,2-dihydropyridin-2-one | Cytochrome P450 monooxygenase iccC | Oxygenation | RHEA | 34755880 |
MMDBr0017462 | dauca-4,7-diene | asperaculane D | Cytochrome P450 monooxygenase aneF | Oxygenation | RHEA | 34755880 |
MMDBr0017463 | dauca-4,7-diene | asperaculane D | Cytochrome P450 monooxygenase aneF | Oxygenation | RHEA | 34755880 |
MMDBr0017464 | asperaculane D | asperaculane E | Cytochrome P450 monooxygenase aneD | Oxygenation | RHEA | 34755880 |
MMDBr0017465 | asperaculane D | asperaculane E | Cytochrome P450 monooxygenase aneD | Oxygenation | RHEA | 34755880 |
MMDBr0017466 | asperaculane E | aculene D | Cytochrome P450 monooxygenase aneG | Oxygenation | RHEA | 34755880 |
MMDBr0017467 | asperaculane E | aculene D | Cytochrome P450 monooxygenase aneG | Oxygenation | RHEA | 34755880 |
MMDBr0017468 | asperaculane E | asperaculane G | Cytochrome P450 monooxygenase aneG | Oxygenation | RHEA | 34755880 |
MMDBr0017469 | asperaculane E | asperaculane G | Cytochrome P450 monooxygenase aneG | Oxygenation | RHEA | 34755880 |
MMDBr0017470 | asperaculane G | aculene D | Cytochrome P450 monooxygenase aneG | Oxygenation | RHEA | 34755880 |
MMDBr0017471 | asperaculane G | aculene D | Cytochrome P450 monooxygenase aneG | Oxygenation | RHEA | 34755880 |
MMDBr0017584 | 5-methylorsellinate | 4,6-dihydroxy-2-(hydroxymethyl)-3-methylbenzoic acid | Cytochrome P450 monooxygenase mpaDE | Oxygenation | RHEA | 34755880 |
MMDBr0017585 | 5-methylorsellinate | 4,6-dihydroxy-2-(hydroxymethyl)-3-methylbenzoic acid | Cytochrome P450 monooxygenase mpaDE | Oxygenation | RHEA | 34755880 |
MMDBr0017596 | Oxygen | Hydrogen Ion | Stellatic acid synthase | Synthesis | RHEA | 34755880 |
MMDBr0017597 | Oxygen | Hydrogen Ion | Stellatic acid synthase | Synthesis | RHEA | 34755880 |
MMDBr0017612 | Oxygen | Asperterpenoid A | Cytochrome P450 monooxygenase astB | Oxygenation | RHEA | 34755880 |
MMDBr0017613 | Oxygen | Asperterpenoid A | Cytochrome P450 monooxygenase astB | Oxygenation | RHEA | 34755880 |
MMDBr0017614 | Asperterpenoid A | Asperterpenoid B | Cytochrome P450 monooxygenase astB | Oxygenation | RHEA | 34755880 |
MMDBr0017615 | Asperterpenoid A | Asperterpenoid B | Cytochrome P450 monooxygenase astB | Oxygenation | RHEA | 34755880 |
MMDBr0017616 | Asperterpenoid A | Asperterpenoid C | Cytochrome P450 monooxygenase astA | Oxygenation | RHEA | 34755880 |
MMDBr0017617 | Asperterpenoid A | Asperterpenoid C | Cytochrome P450 monooxygenase astA | Oxygenation | RHEA | 34755880 |
MMDBr0017624 | Oxygen | Hydrogen Ion | Quiannulatic acid synthase | Synthesis | RHEA | 34755880 |
MMDBr0017625 | Oxygen | Hydrogen Ion | Quiannulatic acid synthase | Synthesis | RHEA | 34755880 |
MMDBr0017630 | Oxygen | Hydrogen Ion | Cytochrome P450 monooxygenase pspC | Oxygenation | RHEA | 34755880 |
MMDBr0017631 | Oxygen | Hydrogen Ion | Cytochrome P450 monooxygenase pspC | Oxygenation | RHEA | 34755880 |
MMDBr0017757 | Lanosterin | 26-hydroxylanosterol | Ganoderic acid synthetase CYP5150L8 | Synthesis | RHEA | 34755880 |
MMDBr0017758 | Lanosterin | 26-hydroxylanosterol | Ganoderic acid synthetase CYP5150L8 | Synthesis | RHEA | 34755880 |
MMDBr0017759 | 26-hydroxylanosterol | 26-oxolanosterol | Ganoderic acid synthetase CYP5150L8 | Synthesis | RHEA | 34755880 |
MMDBr0017760 | 26-hydroxylanosterol | 26-oxolanosterol | Ganoderic acid synthetase CYP5150L8 | Synthesis | RHEA | 34755880 |
MMDBr0017761 | 26-oxolanosterol | 3beta-hydroxy-lanosta-8, 24-dien-26-oic acid | Ganoderic acid synthetase CYP5150L8 | Synthesis | RHEA | 34755880 |
MMDBr0017762 | 26-oxolanosterol | 3beta-hydroxy-lanosta-8, 24-dien-26-oic acid | Ganoderic acid synthetase CYP5150L8 | Synthesis | RHEA | 34755880 |
MMDBr0017763 | ganoderate DM | Hydrogen Ion | Cytochrome P450 monooxygenase CYP512U6 | Oxygenation | RHEA | 34755880 |
MMDBr0017764 | ganoderate DM | Hydrogen Ion | Cytochrome P450 monooxygenase CYP512U6 | Oxygenation | RHEA | 34755880 |
MMDBr0017765 | ganoderate TR | ganoderate Jc | Cytochrome P450 monooxygenase CYP512U6 | Oxygenation | RHEA | 34755880 |
MMDBr0017766 | ganoderate TR | ganoderate Jc | Cytochrome P450 monooxygenase CYP512U6 | Oxygenation | RHEA | 34755880 |
MMDBr0017870 | heme b | 5'-Deoxyadenosine | Anaerobilin synthase | Synthesis | RHEA | 34755880 |
MMDBr0018554 | Oxygen | Sulfite | Alkanesulfonate monooxygenase | Oxygenation | PathBank | 31602464 |
MMDBr0018559 | Oxygen | Sulfite | Alkanesulfonate monooxygenase | Oxygenation | PathBank | 31602464 |
MMDBr0018560 | Oxygen | Sulfite | Alkanesulfonate monooxygenase | Oxygenation | PathBank | 31602464 |
MMDBr0018561 | Oxygen | Sulfite | Alkanesulfonate monooxygenase | Oxygenation | PathBank | 31602464 |
MMDBr0018562 | Oxygen | Sulfite | Alkanesulfonate monooxygenase | Oxygenation | PathBank | 31602464 |
MMDBr0018563 | Oxygen | Sulfite | Alkanesulfonate monooxygenase | Oxygenation | PathBank | 31602464 |
MMDBr0019175 | Uracil | Hydrogen Ion | Pyrimidine monooxygenase RutA | Oxygenation | PathBank | 31602464 |
MMDBr0024553 | Oxygen | Water | Bifunctional cytochrome P450/NADPH--P450 reductase 2 | Reduction | RHEA | 34755880 |
MMDBr0024554 | Oxygen | Water | Alkanal monooxygenase beta chain | Oxygenation | RHEA | 34755880 |
MMDBr0024584 | Oxygen | Water | Limonene hydroxylase | Hydroxylation | RHEA | 34755880 |
MMDBr0024621 | Glycine | Hydrogen Ion | Pyruvate formate-lyase-activating enzyme | Non-hydrolytic bond cleavage (or its reversal) | RHEA | 34755880 |
MMDBr0024731 | Oxygen | Water | Alkanesulfonate monooxygenase | Oxygenation | RHEA | 34755880 |
MMDBr0024732 | Oxygen | Water | Alkanesulfonate monooxygenase | Oxygenation | RHEA | 34755880 |
MMDBr0024741 | Oxygen | (4S)-perillyl alcohol | Limonene hydroxylase | Hydroxylation | RHEA | 34755880 |
MMDBr0025311 | Oxygen | Water | Long-chain alkane monooxygenase | Oxygenation | RHEA | 34755880 |
MMDBr0025312 | Oxygen | Water | Long-chain alkane monooxygenase | Oxygenation | RHEA | 34755880 |
MMDBr0025433 | Oxygen | Water | Biotin biosynthesis cytochrome P450 | Synthesis | RHEA | 34755880 |
MMDBr0025474 | Oxygen | Water | 4-(gamma-L-glutamylamino)butanoyl-[BtrI acyl-carrier protein] monooxygenase BtrO | Oxygenation | RHEA | 34755880 |
MMDBr0025476 | Oxygen | Water | Lanosterol 14-alpha demethylase | Demethylation | RHEA | 34755880 |
MMDBr0025477 | Oxygen | Water | Sterol 14-alpha demethylase | Demethylation | RHEA | 34755880 |
MMDBr0025622 | Oxygen | Water | Cytochrome P450 52-M1 | Hydroxylation | RHEA | 34755880 |
MMDBr0025732 | Oxygen | Water | Cytochrome P450 52-M1 | Hydroxylation | RHEA | 34755880 |
MMDBr0025766 | Glycine | Hydrogen Ion | Putative glycyl-radical enzyme activating enzyme MJ1227 | Reduction; Synthesis | RHEA | 34755880 |
MMDBr0025767 | Glycine | Hydrogen Ion | Isethionate sulfite-lyase activating enzyme | Non-hydrolytic bond cleavage (or its reversal) | RHEA | 34755880 |
MMDBr0025943 | Oxygen | Water | Cytochrome P450 monooxygenase oblB | Oxygenation | RHEA | 34755880 |
MMDBr0025944 | Oxygen | Water | Cytochrome P450 monooxygenase oblB | Oxygenation | RHEA | 34755880 |