MiMeDB: Coprothermobacter proteolyticus DSM 5265 (MMDBm0001482)

Microbe Identification

Microbe name

Coprothermobacter proteolyticus DSM 5265

NCBI Taxonomy ID

309798

Microbe Taxonomy

Superkingdom

Bacteria

Kingdom

Eubacteria

Phylum

Firmicutes

Class

Clostridia

Order

Thermoanaerobacterales

Family

Thermodesulfobiaceae

Genus

Coprothermobacter

Species

proteolyticus

Strain

Microbe Properties

Gram staining properties

Positive

Shape

Bacilli

Mobility

Flagellar presence

Yes

Number of membranes

Oxygen preference

Anaerobe

Optimal temperature

Temperature range

Thermophilic

Habitat

Specialized

Biotic relationship

Free living

Cell arrangement

Pairs - Singles

Sporulation

Pairs - Singles

Metabolism

Acetogen

Energy source

Not Available

Host and Biospecimens

Host	Body site	Biospecimen	Details	Data Source	Reference
Human	Gut	Feces	Expected but not quantified

Health Effects

Host	Related Health Condition	Biospecimen	Microbal response/effect	Data Source	Reference

Related Metabolites

Metabolic Reactions

Reactions

Reaction ID	Precursor	Product	Enzyme	Reaction Type	Data Source	Reference
MMDBr0012889	Pyroglutamic acid	L-Glutamic acid	5-oxoprolinase	Hydrolysis	RHEA	34755880
MMDBr0012953	(R)-Pantoate	Pantothenic acid	Pantothenate synthetase	Ligation; Phosphorylation; Synthesis	RHEA	34755880
MMDBr0012989	D-Alanine	D-Alanyl-D-alanine	D-alanine--D-alanine ligase	Ligation	RHEA	34755880
MMDBr0013001	Acetic acid	Acetyl phosphate	Acetate kinase	Transfer of a formyl group	RHEA	34755880
MMDBr0013226	5-Thymidylic acid	dTDP	Putative thymidylate kinase	Phosphorylation	RHEA	34755880
MMDBr0013234	butanoic acid	Butanoyl phosphate	Probable butyrate kinase	Phosphorylation	RHEA	34755880
MMDBr0013357	(2R)-3-phosphoglyceric acid	(2R)-3-phospho-glyceroyl phosphate	Phosphoglycerate kinase	Phosphorylation	RHEA	34755880
MMDBr0013470	(2R)-2-phosphoglyceric acid	(2R)-3-phosphoglyceric acid	2,3-bisphosphoglycerate-independent phosphoglycerate mutase	Intramolecular transfer of functional group	RHEA	34755880
MMDBr0013547	Uridine triphosphate	Cytidine triphosphate	CTP synthase	Synthesis	RHEA	34755880
MMDBr0013611	D-Glyceraldehyde 3-phosphate	beta-D-Fructose 6-phosphate	Transaldolase	Transfer of aldol group	RHEA	34755880
MMDBr0013659	Guanosine triphosphate	7,8-dihydroneopterin 3'-triphosphate	Bifunctional protein FolKE	Hydrolysis	RHEA	34755880
MMDBr0013755	D-Ribose-5-phosphate	Pseudouridine 5'-phosphate	Pseudouridine-5'-phosphate glycosidase	Transfer of a glycosyl group	RHEA	34755880
MMDBr0013801	Phosphoenolpyruvic acid	UDP-N-Acetyl-3-(1-carboxyvinyl)-D-glucosamine	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	Synthesis	RHEA	34755880
MMDBr0013843	Thymidine	5-Thymidylic acid	Thymidine kinase	Phosphorylation	RHEA	34755880
MMDBr0013848	dCTP	dUMP	dCTP deaminase, dUMP-forming	Deamination	RHEA	34755880
MMDBr0013884	L-Aspartic acid	beta-Alanine	L-aspartate decarboxylase dtxS4	Decarboxylation	RHEA	34755880
MMDBr0013921	(R)-4'-phosphopantetheine	3'-dephospho-CoA	Phosphopantetheine adenylyltransferase	Dephosphorylation	RHEA	34755880
MMDBr0013946	Carbamoylphosphate	N-carbamoyl-L-aspartate	Protein pyrABCN	Transfer of a carbamoyl group	RHEA	34755880
MMDBr0013970	L-Alanine	D-Alanine	L-alanine/L-glutamate racemase	Racemization	RHEA	34755880
MMDBr0014193	2-Methyl-4-amino-5-hydroxymethylpyrimidine diphosphate	thiamine phosphate	Probable thiamine biosynthetic bifunctional enzyme	Synthesis	RHEA	34755880
MMDBr0014229	5-Amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate	(2S)-2-[5-Amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinic acid	Phosphoribosylaminoimidazole-succinocarboxamide synthase	Synthesis	RHEA	34755880
MMDBr0014251	(6R)-5,10-methylene-5,6,7,8-tetrahydrofolic acid	5,10-Methenyltetrahydrofolate	C-1-tetrahydrofolate synthase, cytoplasmic	Synthesis	RHEA	34755880
MMDBr0014257	nicotinate beta-D-ribonucleotide	Nicotinic acid adenine dinucleotide	Probable nicotinate-nucleotide adenylyltransferase	Reversible transfer of an adenylyl group	RHEA	34755880
MMDBr0014369	5,10-Methenyltetrahydrofolate	(6S)-10-formyltetrahydrofolic acid	C-1-tetrahydrofolate synthase, cytoplasmic	Reversible cyclization	RHEA	34755880
MMDBr0014426	4-Methyl-5-(2-hydroxyethyl)-thiazole	4-methyl-5-(2-phosphooxyethyl)-thiazole	Probable thiamine biosynthetic bifunctional enzyme	Phosphorylation	RHEA	34755880
MMDBr0014559	beta-D-Ribopyranose	beta-D-ribofuranose	L-fucose mutarotase	Mutarotation	RHEA	34755880
MMDBr0017926	L-Glutamine	Cytidine triphosphate	CTP synthase	Synthesis	RHEA	34755880
MMDBr0016358	2-[(2R,5Z)-2-Carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate	thiamine phosphate	Probable thiamine biosynthetic bifunctional enzyme	Synthesis	RHEA	34755880
MMDBr0016359	2-(2-Carboxy-4-methylthiazol-5-yl)ethyl phosphate	thiamine phosphate	Probable thiamine biosynthetic bifunctional enzyme	Synthesis	RHEA	34755880
MMDBr0016813	2-Aminobenzoic acid	2-(4-dimethylaminophenyl)diazenylbenzoic acid	FMN-dependent NADPH-azoreductase	Reduction	RHEA	34755880
MMDBr0017871	(6R)-5,10-methylene-5,6,7,8-tetrahydrofolic acid	(6S)-5,6,7,8-tetrahydrofolic acid	Serine hydroxymethyltransferase	Methylation	RHEA	34755880
MMDBr0017874	L-Glutamine	L-Glutamic acid	Thermolabile glutaminase	Synthesis	RHEA	34755880
MMDBr0024401	L-Serine	Adenosine 3',5'-diphosphate	Holo-[acyl-carrier-protein] synthase	Dehydrogenation; Synthesis	RHEA	34755880
MMDBr0024411	L-Serine	Hydrogen Ion	Type-2 serine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024435	Deoxyribose 5-phosphate	Acetaldehyde	Deoxyribose-phosphate aldolase	Aldol addition (or reverse)	RHEA	34755880
MMDBr0024474	L-Proline	diphosphate	Proline--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024483	L-Glutamine	L-Glutamic acid	Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C	Amide group addition	RHEA	34755880
MMDBr0024522	Glycine	diphosphate	Glycine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024546	(6R)-5,10-methylene-5,6,7,8-tetrahydrofolic acid	(6S)-5,6,7,8-tetrahydrofolic acid	Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO	Methylation	RHEA	34755880
MMDBr0024568	L-Glutamine	L-Glutamic acid	Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C	Amide group addition	RHEA	34755880
MMDBr0024745	L-Glutamic acid	diphosphate	Glutamate--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024774	Glycine	Carbon dioxide	Probable glycine dehydrogenase (decarboxylating) subunit 1	Dehydrogenation	RHEA	34755880
MMDBr0024778	(6S)-10-formyltetrahydrofolic acid	(6S)-5,6,7,8-tetrahydrofolic acid	Methionyl-tRNA formyltransferase	Transfer of a formyl group	RHEA	34755880
MMDBr0024813	Dimethylallylpyrophosphate	diphosphate	tRNA dimethylallyltransferase	Transfer of a dimethylallyl group	RHEA	34755880
MMDBr0024967	S-Adenosylmethionine	S-Adenosylhomocysteine	tRNA (guanine(37)-N1)-methyltransferase Trm5b	Methylation	RHEA	34755880
MMDBr0024974	S-Adenosylmethionine	5'-Deoxyadenosine	tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase	Synthesis	RHEA	34755880
MMDBr0025050	L-Alanine	(S)-8-amino-7-oxononanoic acid	Putative 8-amino-7-oxononanoate synthase	Ligation; Synthesis	RHEA	34755880
MMDBr0025060	L-Serine	Hydrogen Ion	Type-2 serine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0025071	S-Adenosylmethionine	S-Adenosylhomocysteine	tRNA (guanine-N(7)-)-methyltransferase	Methylation	RHEA	34755880
MMDBr0025085	S-Adenosylmethionine	S-Adenosylhomocysteine	Putative ribosomal RNA large subunit methyltransferase H	Methylation	RHEA	34755880
MMDBr0025104	S-Adenosylmethionine	S-Adenosylhomocysteine	Ribosomal RNA small subunit methyltransferase I	Methylation	RHEA	34755880
MMDBr0025105	S-Adenosylmethionine	S-Adenosylhomocysteine	Ribosomal RNA small subunit methyltransferase H	Methylation	RHEA	34755880
MMDBr0025777	(6R)-5,10-methylene-5,6,7,8-tetrahydrofolic acid	(6S)-5,6,7,8-tetrahydrofolic acid	Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO	Methylation	RHEA	34755880
MMDBr0025921	Hydrogen Ion	NAD	FMN-dependent NADH:quinone oxidoreductase	Redox reaction	RHEA	34755880

Genome Data

Genome Link

Not Available

Genome Length

Not Available

# Predicted Proteins

GenBank Sequence Modification Date

17-FEB-2022

MiMeDB Deposition Date

Reference

PMID: 17704766

Source Links

GenBank