Hydrolysis

Reaction Identification
Reaction IDMMDBr0012889
Reaction typeHydrolysis
Sub-SystemNot Available
In non-microbes0
In microbes246
Data SourcesRHEA;
Metabolism
PrecursorReactionProduct
Pyroglutamic acid

5-oxoprolinase

Hydrolysis

L-Glutamic acid
Microbe IDOrganismKindgomPhylumOxygen preference
MMDBm0098378Saccharomyces cerevisiaeFungiAscomycota
MMDBm0085327Pestalotiopsis ficiFungiAscomycota
MMDBm0001178Acidovorax citrulliEubacteriaProteobacteriaAerobe
MMDBm0001183Acinetobacter sp. ADP1EubacteriaProteobacteriaAerobe
MMDBm0001189Acinetobacter baumanniiEubacteriaProteobacteriaAerobe
MMDBm0001188Acinetobacter baumanniiEubacteriaProteobacteriaAerobe
MMDBm0001187Acinetobacter baumanniiEubacteriaProteobacteriaAerobe
MMDBm0001184Acinetobacter baumanniiEubacteriaProteobacteriaAerobe
MMDBm0001186Acinetobacter baumanniiEubacteriaProteobacteriaAerobe
MMDBm0000028Bacillus haloduransEubacteriaFirmicutesFacultative aerobe
MMDBm0001213Alkaliphilus metalliredigensEubacteriaFirmicutesAnaerobe
MMDBm0001237Arthrobacter sp. FB24EubacteriaActinobacteriaAerobe
MMDBm0001245Azorhizobium caulinodansEubacteriaProteobacteria
MMDBm0001244Azoarcus sp. BH72EubacteriaProteobacteriaMicroaerophilic
MMDBm0001268Bacillus anthracisEubacteriaFirmicutesFacultative aerobe
MMDBm0001267Bacillus anthracisEubacteriaFirmicutesFacultative aerobe
MMDBm0000460Bacillus anthracisEubacteriaFirmicutes
MMDBm0001263Bacillus cereusEubacteriaFirmicutesAerobe
MMDBm0001249Bacillus cereusEubacteriaFirmicutesAerobe
MMDBm0001266Bacillus cereusEubacteriaFirmicutesAerobe
MMDBm0001262Bacillus cereusEubacteriaFirmicutesAerobe
MMDBm0000026Bacillus cereusEubacteriaFirmicutesAerobe
MMDBm0000027Bacillus cytotoxicusEubacteriaFirmicutesAerobe
MMDBm0001265Bacillus cereusEubacteriaFirmicutesAerobe
MMDBm0001252Bacillus cereusEubacteriaFirmicutesAerobe
MMDBm0001256Bacillus cereusEubacteriaFirmicutesAerobe
MMDBm0001254Bacillus thuringiensisEubacteriaFirmicutesFacultative aerobe
MMDBm0001255Bacillus licheniformisEubacteriaFirmicutesFacultative aerobe
MMDBm0001261Bacillus weihenstephanensisEubacteriaFirmicutesAerobe
MMDBm0001260Bacillus pumilusEubacteriaFirmicutesAerobe
MMDBm0001257Bacillus clausiiEubacteriaFirmicutesFacultative anaerobe
MMDBm0001248Bacillus subtilisEubacteriaFirmicutesFacultative aerobe
MMDBm0001259amyloliquefaciensEubacteriaFirmicutesAerobe
MMDBm0001965Bordetella parapertussisEubacteriaProteobacteriaAerobe
MMDBm0001966Bordetella pertussisEubacteriaProteobacteriaAerobe
MMDBm0000097Brevibacillus brevisEubacteriaFirmicutesAerobe
MMDBm0001346Burkholderia ambifariaEubacteriaProteobacteriaFacultative aerobe
MMDBm0001345Burkholderia cenocepaciaEubacteriaProteobacteriaFacultative aerobe
MMDBm0001336Burkholderia ambifariaEubacteriaProteobacteriaFacultative aerobe
MMDBm0001332Burkholderia sp. 383EubacteriaProteobacteriaFacultative aerobe
MMDBm0001344Burkholderia multivoransEubacteriaProteobacteriaAerobe
MMDBm0001342Burkholderia malleiEubacteriaProteobacteriaAerobe
MMDBm0001339Burkholderia malleiEubacteriaProteobacteriaAerobe
MMDBm0001329Burkholderia malleiEubacteriaProteobacteriaAerobe
MMDBm0001338Burkholderia malleiEubacteriaProteobacteriaAerobe
MMDBm0001333Burkholderia thailandensisEubacteriaProteobacteriaAerobe
MMDBm0001343Burkholderia vietnamiensisEubacteriaProteobacteriaFacultative aerobe
MMDBm0001358Thermoanaerobacter tengcongensisEubacteriaFirmicutesAnaerobe
MMDBm0001372Campylobacter jejuniEubacteriaProteobacteriaMicroaerophilic
MMDBm0001369Campylobacter jejuniEubacteriaProteobacteriaMicroaerophilic
MMDBm0001367Campylobacter jejuniEubacteriaProteobacteriaMicroaerophilic
MMDBm0001368Campylobacter jejuniEubacteriaProteobacteriaMicroaerophilic
MMDBm0001971Campylobacter jejuniEubacteriaProteobacteriaMicroaerophilic
MMDBm0001406Carboxydothermus hydrogenoformansEubacteriaFirmicutesAnaerobe
MMDBm0001445Chloroflexus aurantiacusEubacteriaChloroflexiAnaerobe
MMDBm0001446Chloroflexus aggregansEubacteriaChloroflexiFacultative
MMDBm0001447Chloroflexus sp. Y-400-flEubacteriaChloroflexi
MMDBm0001449Chromohalobacter salexigensEubacteriaProteobacteriaAerobe
MMDBm0001980Chromobacterium violaceumEubacteriaProteobacteriaFacultatively anaerobe
MMDBm0001450Citrobacter koseriEubacteriaProteobacteriaFacultatively anaerobe
MMDBm0000116beijerinckiiEubacteriaFirmicutesAnaerobe
MMDBm0000109Clostridioides difficileEubacteriaFirmicutesAnaerobe
MMDBm0001466Clostridium kluyveriEubacteriaFirmicutesAnaerobe
MMDBm0001458Clostridium kluyveriEubacteriaFirmicutesAnaerobe
MMDBm0001482Coprothermobacter proteolyticusEubacteriaFirmicutesAnaerobe
MMDBm0001486Corynebacterium efficiensEubacteriaActinobacteriaFacultative aerobe
MMDBm0001487Corynebacterium glutamicumEubacteriaActinobacteriaFacultative aerobe
MMDBm0001485Corynebacterium glutamicumEubacteriaActinobacteriaFacultative aerobe
MMDBm0001484Corynebacterium jeikeiumEubacteriaActinobacteriaFacultative aerobe
MMDBm0001501Cronobacter sakazakiiEubacteriaProteobacteriaAnaerobe
MMDBm0001506Cupriavidus metalliduransEubacteriaProteobacteriaFacultative
MMDBm0001504Ralstonia eutrophaEubacteriaProteobacteriaFacultative aerobe
MMDBm0001505Ralstonia eutrophaEubacteriaProteobacteriaFacultative aerobe
MMDBm0001507Cupriavidus taiwanensisEubacteriaProteobacteriaFacultative
MMDBm0002383Propionibacterium acnesEubacteriaActinobacteriaAnaerobe
MMDBm0001524Deinococcus radiodurans EubacteriaDeinococcus-thermusAerobe
MMDBm0001588Escherichia coliEubacteriaProteobacteriaFacultative anaerobe
MMDBm0001594Escherichia coliEubacteriaProteobacteriaFacultative anaerobe
MMDBm0001598Escherichia coliEubacteriaProteobacteriaFacultative anaerobe
MMDBm0001600Escherichia coliEubacteriaProteobacteriaFacultative anaerobe
MMDBm0542442Escherichia coliEubacteriaProteobacteriaFacultative anaerobe
MMDBm0001592Escherichia coliEubacteriaProteobacteriaFacultative anaerobe
MMDBm0001601Escherichia coliEubacteriaProteobacteriaFacultative anaerobe
MMDBm0001599Escherichia coliEubacteriaProteobacteriaFacultative anaerobe
MMDBm0001597Escherichia coliEubacteriaProteobacteriaFacultative anaerobe
MMDBm0001602Escherichia coliEubacteriaProteobacteriaFacultative anaerobe
MMDBm0001591Escherichia coliEubacteriaProteobacteriaFacultative anaerobe
MMDBm0001589Escherichia coliEubacteriaProteobacteriaFacultative anaerobe
MMDBm0001587Escherichia coliEubacteriaProteobacteriaFacultative anaerobe
MMDBm0001586Escherichia coliEubacteriaProteobacteriaFacultative anaerobe
MMDBm0000162Escherichia coliEubacteriaProteobacteriaFacultative anaerobe
MMDBm0001590Escherichia coliEubacteriaProteobacteriaFacultative anaerobe
MMDBm0541555Escherichia coliEubacteriaProteobacteriaFacultative anaerobe
MMDBm0001595Escherichia coliEubacteriaProteobacteriaFacultative anaerobe
MMDBm0001593Escherichia coliEubacteriaProteobacteriaFacultative anaerobe
MMDBm0000167Escherichia coliEubacteriaProteobacteriaFacultative anaerobe
MMDBm0000169Escherichia coliEubacteriaProteobacteriaFacultative anaerobe
MMDBm0001576tasmaniensisEubacteriaProteobacteriaFacultative anaerobe
MMDBm0001596Escherichia fergusoniiEubacteriaProteobacteriaAerobe
MMDBm0000185Fusobacterium nucleatumEubacteriaFusobacteriaAnaerobe
MMDBm0001636Geobacillus kaustophilusEubacteriaFirmicutesAerobe
MMDBm0001637thermodenitrificansEubacteriaFirmicutesFacultative aerobe
MMDBm0001654Gluconobacter oxydansEubacteriaProteobacteriaAerobe
MMDBm0001659Haemophilus influenzaeEubacteriaProteobacteriaAerobe; facultative anaerobe
MMDBm0001660Haemophilus influenzaeEubacteriaProteobacteriaAerobe; facultative anaerobe
MMDBm0001661Haemophilus influenzaeEubacteriaProteobacteriaAerobe; facultative anaerobe
MMDBm0001658Haemophilus influenzaeEubacteriaProteobacteriaAerobe; facultative anaerobe
MMDBm0001705Haemophilus somnusEubacteriaProteobacteriaAerobe; facultative anaerobe
MMDBm0001699Heliobacterium modesticaldumEubacteriaFirmicutesAnaerobe
MMDBm0001706Haemophilus somnusEubacteriaProteobacteriaAerobe; facultative anaerobe
MMDBm0001725Kineococcus radiotoleransEubacteriaActinobacteriaAerobe
MMDBm0001728Klebsiella pneumoniaeEubacteriaProteobacteriaFacultative anaerobe
MMDBm0001727Klebsiella pneumoniaeEubacteriaProteobacteriaFacultative anaerobe
MMDBm0001729Kocuria rhizophilaEubacteriaActinobacteriaAerobe
MMDBm0001747Limosilactobacillus fermentumEubacteriaFirmicutesFacultative anaerobe; microaerophile
MMDBm0001795Macrococcus caseolyticusEubacteriaFirmicutesAerobe
MMDBm0001865Methylococcus capsulatusEubacteriaProteobacteriaAerobe
MMDBm0001887Mycobacterium aviumEubacteriaActinobacteriaAerobe
MMDBm0001893Mycobacterium gilvumEubacteriaActinobacteriaAerobe
MMDBm0001898Mycobacterium lepraeEubacteriaActinobacteriaAerobe
MMDBm0001881Mycobacterium lepraeEubacteriaActinobacteriaAerobe
MMDBm0001897Mycobacterium marinumEubacteriaActinobacteriaAerobe
MMDBm0001883Mycobacterium aviumEubacteriaActinobacteriaAerobe
MMDBm0001885Mycobacterium ulceransEubacteriaActinobacteriaAerobe
MMDBm0001924Natranaerobius thermophilusEubacteriaFirmicutesObligate anaerobe
MMDBm0001932Neisseria meningitidisEubacteriaProteobacteriaAerobe
MMDBm0001930Neisseria meningitidisEubacteriaProteobacteriaAerobe
MMDBm0001929Neisseria meningitidisEubacteriaProteobacteriaAerobe
MMDBm0001931Neisseria meningitidisEubacteriaProteobacteriaAerobe
MMDBm0001941Nitrobacter hamburgensisEubacteriaProteobacteriaAerobe
MMDBm0001940Nitrobacter winogradskyiEubacteriaProteobacteriaAerobe; anaerobe
MMDBm0001950Nocardia farcinicaEubacteriaActinobacteriaAerobe
MMDBm0001973Oceanobacillus iheyensisEubacteriaFirmicutesAerobe
MMDBm0001347Burkholderia phymatumEubacteriaProteobacteriaFacultative aerobe
MMDBm0001348Burkholderia phytofirmansEubacteriaProteobacteriaAerobe
MMDBm0001334Burkholderia xenovoransEubacteriaProteobacteriaAerobe
MMDBm0002346Pectobacterium atrosepticumEubacteriaProteobacteriaAnaerobe
MMDBm0002347Pectobacterium carotovorumEubacteriaProteobacteriaFacultative anaerobe
MMDBm0002361Photorhabdus luminescensEubacteriaProteobacteriaFacultative
MMDBm0002393Pseudomonas fluorescensEubacteriaProteobacteriaAerobe
MMDBm0002397Pseudomonas fluorescensEubacteriaProteobacteriaAerobe
MMDBm0002423Pyrococcus abyssiArchaeaEuryarchaeotaAnaerobe
MMDBm0002425Pyrococcus furiosusArchaeaEuryarchaeotaAnaerobe
MMDBm0002424Pyrococcus horikoshiiArchaeaEuryarchaeotaAnaerobe
MMDBm0002430Ralstonia pickettiiEubacteriaProteobacteriaAerobe
MMDBm0001204Rhodoferax ferrireducensEubacteriaProteobacteriaFacultative anaerobe
MMDBm0002450Rhodopseudomonas palustrisEubacteriaProteobacteriaAerobe; anaerobe
MMDBm0002453Rhodopseudomonas palustrisEubacteriaProteobacteriaAerobe; anaerobe
MMDBm0002449Rhodopseudomonas palustrisEubacteriaProteobacteriaAerobe; anaerobe
MMDBm0002451Rhodopseudomonas palustrisEubacteriaProteobacteriaAerobe; anaerobe
MMDBm0002452Rhodopseudomonas palustrisEubacteriaProteobacteriaAerobe; anaerobe
MMDBm0002454Rhodopseudomonas palustrisEubacteriaProteobacteriaAerobe; anaerobe
MMDBm0002482Ruegeria pomeroyiEubacteriaProteobacteriaAerobe
MMDBm0002498Salmonella entericaEubacteriaProteobacteriaFacultative anaerobe
MMDBm0547793Salmonella entericaEubacteriaProteobacteriaFacultative anaerobe
MMDBm0548594Salmonella entericaEubacteriaProteobacteriaFacultative anaerobe
MMDBm0002499Salmonella entericaEubacteriaProteobacteriaFacultative anaerobe
MMDBm0549171Salmonella entericaEubacteriaProteobacteriaFacultative anaerobe
MMDBm0002500Salmonella entericaEubacteriaProteobacteriaFacultative anaerobe
MMDBm0002496Salmonella entericaEubacteriaProteobacteriaFacultative anaerobe
MMDBm0002495Salmonella entericaEubacteriaProteobacteriaFacultative anaerobe
MMDBm0550379Salmonella entericaEubacteriaProteobacteriaFacultative anaerobe
MMDBm0550426Salmonella entericaEubacteriaProteobacteriaFacultative anaerobe
MMDBm0550377Salmonella entericaEubacteriaProteobacteriaFacultative anaerobe
MMDBm0550587Salmonella entericaEubacteriaProteobacteriaFacultative anaerobe
MMDBm0550758Salmonella entericaEubacteriaProteobacteriaFacultative anaerobe
MMDBm0002492Salmonella entericaEubacteriaProteobacteriaFacultative anaerobe
MMDBm0002506Serratia proteamaculansEubacteriaProteobacteriaFacultative
MMDBm0002535Shigella boydiiEubacteriaProteobacteriaFacultative anaerobe
MMDBm0002533Shigella boydiiEubacteriaProteobacteriaFacultative anaerobe
MMDBm0002532Shigella dysenteriaeEubacteriaProteobacteriaFacultative anaerobe
MMDBm0002534Shigella flexneriEubacteriaProteobacteriaFacultative anaerobe
MMDBm0000368Shigella flexneriEubacteriaProteobacteriaFacultative anaerobe
MMDBm0002531Shigella sonneiEubacteriaProteobacteriaFacultative anaerobe
MMDBm0002571Staphylococcus aureusEubacteriaFirmicutesFacultative anaerobe
MMDBm0002569Staphylococcus aureusEubacteriaFirmicutesFacultative anaerobe
MMDBm0778392Staphylococcus aureusEubacteriaFirmicutesFacultative anaerobe
MMDBm0002567Staphylococcus aureusEubacteriaFirmicutesFacultative anaerobe
MMDBm0002568Staphylococcus aureusEubacteriaFirmicutesFacultative anaerobe
MMDBm0002565Staphylococcus aureusEubacteriaFirmicutesFacultative anaerobe
MMDBm0002557Staphylococcus aureusEubacteriaFirmicutesFacultative anaerobe
MMDBm0002570Staphylococcus aureusEubacteriaFirmicutesFacultative anaerobe
MMDBm0002556Staphylococcus aureusEubacteriaFirmicutesFacultative anaerobe
MMDBm0002555Staphylococcus aureusEubacteriaFirmicutesFacultative anaerobe
MMDBm0002558Staphylococcus aureusEubacteriaFirmicutesFacultative anaerobe
MMDBm0002559Staphylococcus aureusEubacteriaFirmicutesFacultative anaerobe
MMDBm0002572Staphylococcus aureusEubacteriaFirmicutesFacultative anaerobe
MMDBm0002561Staphylococcus aureusEubacteriaFirmicutesFacultative anaerobe
MMDBm0002573Staphylococcus carnosusEubacteriaFirmicutesFacultative anaerobe
MMDBm0002560Staphylococcus epidermidisEubacteriaFirmicutesFacultative anaerobe
MMDBm0002562Staphylococcus epidermidisEubacteriaFirmicutesFacultative anaerobe
MMDBm0002563Staphylococcus haemolyticusEubacteriaFirmicutesFacultative anaerobe
MMDBm0002564Staphylococcus saprophyticusEubacteriaFirmicutesAerobe
MMDBm0002634Streptomyces avermitilisEubacteriaActinobacteriaAerobe
MMDBm0002635Streptomyces coelicolorEubacteriaActinobacteriaAerobe
MMDBm0002636Streptomyces griseusEubacteriaActinobacteriaAerobe
MMDBm0002658Symbiobacterium thermophilumEubacteriaFirmicutesMicroaerophilic
MMDBm0002670Syntrophobacter fumaroxidansEubacteriaProteobacteriaAnaerobe
MMDBm0002690Thermococcus kodakarensisArchaeaEuryarchaeotaAnaerobe
MMDBm0002691Thermococcus onnurineusArchaeaEuryarchaeotaAnaerobe
MMDBm0002693Thermococcus sibiricusArchaeaEuryarchaeotaAnaerobic
MMDBm0001983Thermus thermophilusEubacteriaDeinococcus-thermusAerobe
MMDBm0001985Thermus thermophilusEubacteriaDeinococcus-thermusAerobe
MMDBm0002722Tolumonas auensisEubacteriaProteobacteriaFacultative
MMDBm0002743Vibrio choleraeEubacteriaProteobacteriaFacultative anaerobe
MMDBm0610847Vibrio campbelliiEubacteriaProteobacteria
MMDBm0002739Vibrio choleraeEubacteriaProteobacteriaFacultative anaerobe
MMDBm0002746Vibrio choleraeEubacteriaProteobacteriaFacultative anaerobe
MMDBm0002741Vibrio parahaemolyticusEubacteriaProteobacteriaFacultative anaerobe
MMDBm0002740Vibrio vulnificusEubacteriaProteobacteriaFacultative anaerobe
MMDBm0002742Vibrio vulnificusEubacteriaProteobacteriaFacultative anaerobe
MMDBm0002781Yersinia enterocoliticaEubacteriaProteobacteriaFacultative anaerobe
MMDBm0002783pseudotuberculosisEubacteriaProteobacteriaFacultative anaerobe
MMDBm0002780Yersinia pestisEubacteriaProteobacteriaFacultative anaerobe
MMDBm0002786pseudotuberculosisEubacteriaProteobacteriaFacultative anaerobe
MMDBm0562461Yersinia pestisEubacteriaProteobacteria
MMDBm0002784Yersinia pestisEubacteriaProteobacteriaFacultative anaerobe
MMDBm0002779Yersinia pestisEubacteriaProteobacteriaFacultative anaerobe
MMDBm0002782Yersinia pestisEubacteriaProteobacteriaFacultative anaerobe
MMDBm0002778pseudotuberculosisEubacteriaProteobacteriaFacultative anaerobe
MMDBm0002785pseudotuberculosisEubacteriaProteobacteriaFacultative anaerobe
MMDBm0001200Agrobacterium tumefaciensEubacteriaProteobacteriaAerobe
MMDBm0001964Bordetella bronchisepticaEubacteriaProteobacteriaAerobe
MMDBm0001308Bradyrhizobium japonicumEubacteriaProteobacteriaAerobe
MMDBm0001330Burkholderia pseudomalleiEubacteriaProteobacteriaAerobe
MMDBm0002391Pseudomonas aeruginosaEubacteriaProteobacteriaAerobe
MMDBm0002392Pseudomonas putidaEubacteriaProteobacteriaAerobe
MMDBm0002394Pseudomonas syringaeEubacteriaProteobacteriaAerobe
MMDBm0002429Ralstonia solanacearumEubacteriaProteobacteriaAerobe
MMDBm0001200Agrobacterium tumefaciensEubacteriaProteobacteriaAerobe
MMDBm0001964Bordetella bronchisepticaEubacteriaProteobacteriaAerobe
MMDBm0001308Bradyrhizobium japonicumEubacteriaProteobacteriaAerobe
MMDBm0001330Burkholderia pseudomalleiEubacteriaProteobacteriaAerobe
MMDBm0002391Pseudomonas aeruginosaEubacteriaProteobacteriaAerobe
MMDBm0002392Pseudomonas putidaEubacteriaProteobacteriaAerobe
MMDBm0002394Pseudomonas syringaeEubacteriaProteobacteriaAerobe
MMDBm0002429Ralstonia solanacearumEubacteriaProteobacteriaAerobe
MMDBm0002391Pseudomonas aeruginosaEubacteriaProteobacteriaAerobe
MMDBm0002394Pseudomonas syringaeEubacteriaProteobacteriaAerobe
MMDBm0001248Bacillus subtilisEubacteriaFirmicutesFacultative aerobe
MMDBm0542442Escherichia coliEubacteriaProteobacteriaFacultative anaerobe
MMDBm0541555Escherichia coliEubacteriaProteobacteriaFacultative anaerobe
MMDBm0001658Haemophilus influenzaeEubacteriaProteobacteriaAerobe; facultative anaerobe
MMDBm0001248Bacillus subtilisEubacteriaFirmicutesFacultative aerobe
MMDBm0541555Escherichia coliEubacteriaProteobacteriaFacultative anaerobe
MMDBm0001658Haemophilus influenzaeEubacteriaProteobacteriaAerobe; facultative anaerobe