MiMeDB: Chloroflexus aggregans DSM 9485 (MMDBm0001446)

Microbe Identification

Microbe name

Chloroflexus aggregans DSM 9485

NCBI Taxonomy ID

326427

Microbe Taxonomy

Superkingdom

Bacteria

Kingdom

Eubacteria

Phylum

Chloroflexi

Class

Chloroflexi

Order

Chloroflexales

Family

Chloroflexaceae

Genus

Chloroflexus

Species

aggregans

Strain

Microbe Properties

Gram staining properties

Positive

Shape

Filamentous

Mobility

Yes

Flagellar presence

Number of membranes

Oxygen preference

Facultative

Optimal temperature

Not Available

Temperature range

Thermophilic

Habitat

Specialized

Biotic relationship

Free living

Cell arrangement

Filaments

Sporulation

Not Available

Metabolism

Not Available

Energy source

Photosynthetic

Host and Biospecimens

Host	Body site	Biospecimen	Details	Data Source	Reference
Human	Gut	Feces	Expected but not quantified

Health Effects

Host	Related Health Condition	Biospecimen	Microbal response/effect	Data Source	Reference

Related Metabolites

Metabolic Reactions

Reactions

Reaction ID	Precursor	Product	Enzyme	Reaction Type	Data Source	Reference
MMDBr0012860	(2R)-2-phosphoglyceric acid	Water	Enolase	Enolization	RHEA	34755880
MMDBr0012889	Pyroglutamic acid	ADP	5-oxoprolinase	Hydrolysis	RHEA	34755880
MMDBr0012953	(R)-Pantoate	Pantothenic acid	Pantothenate synthetase	Ligation; Phosphorylation; Synthesis	RHEA	34755880
MMDBr0012970	D-erythro-1-(Imidazol-4-yl)glycerol 3-phosphate	3-(Imidazol-4-yl)-2-oxopropyl phosphate	Imidazoleglycerol-phosphate dehydratase	Hydration/dehydration of C-O bond; Synthesis	RHEA	34755880
MMDBr0012988	5,6-Dimethylbenzimidazole	N1-(5-Phospho-a-D-ribosyl)-5,6-dimethylbenzimidazole	Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase	Transfer of a ribosyl group	RHEA	34755880
MMDBr0013027	Adenosine triphosphate	ADP	Cytidylate kinase	Phosphorylation	RHEA	34755880
MMDBr0013038	diphosphate	Phosphoribosyl pyrophosphate	Tryptophan biosynthesis protein TrpCD	Transfer of a ribosyl group	RHEA	34755880
MMDBr0013046	(6R)-5,10-methylene-5,6,7,8-tetrahydrofolic acid	(6S)-5,6,7,8-tetrahydrofolic acid	3-methyl-2-oxobutanoate hydroxymethyltransferase	Methylation	RHEA	34755880
MMDBr0013062	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin	4a-Carbinolamine tetrahydrobiopterin	Putative pterin-4-alpha-carbinolamine dehydratase	Hydration/dehydration of C-O bond	RHEA	34755880
MMDBr0013098	NADP(+)	Hydrogen Ion	UDP-N-acetylenolpyruvoylglucosamine reductase	Reduction	RHEA	34755880
MMDBr0013173	diphosphate	Phosphoribosyl pyrophosphate	Bifunctional protein PyrR	Transfer of phosphoribosyl group	RHEA	34755880
MMDBr0013179	Adenosine triphosphate	ADP	Replicase large subunit	Synthesis of a primer	RHEA	34755880
MMDBr0013221	(R)-2,3-Dihydroxy-3-methylpentanoate	(S)-2-ethyl-2-hydroxy-3-oxobutanoic acid	Ketol-acid reductoisomerase, mitochondrial	Isomerization	RHEA	34755880
MMDBr0013295	(S)-4-Amino-5-oxopentanoate	5-Aminolevulinic acid	Glutamate-1-semialdehyde 2,1-aminomutase	Non-hydrolytic bond cleavage (or its reversal)	RHEA	34755880
MMDBr0013333	Adenosine triphosphate	ADP	Protein ARG5,6, mitochondrial	Phosphorylation	RHEA	34755880
MMDBr0013339	aldehydo-D-ribose 5-phosphate	D-Ribulose 5-phosphate	Bifunctional ribokinase/ribose-5-phosphate isomerase A	Isomerization	RHEA	34755880
MMDBr0013357	(2R)-3-phosphoglyceric acid	(2R)-3-phospho-glyceroyl phosphate	Phosphoglycerate kinase	Phosphorylation	RHEA	34755880
MMDBr0013431	1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide	5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase	Isomerization	RHEA	34755880
MMDBr0013470	(2R)-2-phosphoglyceric acid	(2R)-3-phosphoglyceric acid	2,3-bisphosphoglycerate-independent phosphoglycerate mutase	Intramolecular transfer of functional group	RHEA	34755880
MMDBr0013495	Adenosine triphosphate	ADP	ATP-dependent 6-phosphofructokinase	Phosphorylation	RHEA	34755880
MMDBr0013547	Adenosine triphosphate	ADP	CTP synthase	Synthesis	RHEA	34755880
MMDBr0013571	Adenosine triphosphate	ADP	Putative uridine kinase DAS2	Phosphorylation	RHEA	34755880
MMDBr0013674	Adenosine triphosphate	ADP	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial	Ligation	RHEA	34755880
MMDBr0013792	Adenosine triphosphate	ADP	NAD kinase	Phosphorylation	RHEA	34755880
MMDBr0013843	Adenosine triphosphate	ADP	Thymidine kinase	Phosphorylation	RHEA	34755880
MMDBr0013895	L-Glutamic-gamma-semialdehyde	Hydrogen Ion	Gamma-glutamyl phosphate reductase	Reduction	RHEA	34755880
MMDBr0013921	(R)-4'-phosphopantetheine	3'-dephospho-CoA	Phosphopantetheine adenylyltransferase	Dephosphorylation	RHEA	34755880
MMDBr0013929	Hydrogen Ion	Carbon dioxide	Uroporphyrinogen decarboxylase	Decarboxylation	RHEA	34755880
MMDBr0013946	Carbamoylphosphate	Hydrogen Ion	Protein pyrABCN	Transfer of a carbamoyl group	RHEA	34755880
MMDBr0013966	(6S)-5,6,7,8-tetrahydrofolic acid	(6S)-10-formyltetrahydrofolic acid	C-1-tetrahydrofolate synthase, cytoplasmic	Ligation; Synthesis	RHEA	34755880
MMDBr0014061	5-O-(1-Carboxyvinyl)-3-phosphoshikimate	Chorismate	Chorismate synthase	Synthesis	RHEA	34755880
MMDBr0014083	Shikimate 3-phosphate	5-O-(1-Carboxyvinyl)-3-phosphoshikimate	Pentafunctional AROM polypeptide	Synthesis; Dehydration and isomerisation; Oxidation; Phosphorylation; Transfer of a carboxyvinyl group	RHEA	34755880
MMDBr0014105	(S)-malate(2-)	Hydrogen Ion	Malate dehydrogenase	Dehydrogenation	RHEA	34755880
MMDBr0014126	Adenosine triphosphate	ADP	Glycerol kinase	Phosphorylation	RHEA	34755880
MMDBr0014167	(R)-2,3-Dihydroxy-isovalerate	(2S)-2-acetolactic acid	Ketol-acid reductoisomerase, mitochondrial	Isomerization	RHEA	34755880
MMDBr0014227	(S)-4-hydroxy-2-oxopentanoic acid	Acetaldehyde	4-hydroxy-2-oxovalerate aldolase	Aldol addition (or reverse)	RHEA	34755880
MMDBr0014229	5-Amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate	(2S)-2-[5-Amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinic acid	Phosphoribosylaminoimidazole-succinocarboxamide synthase	Synthesis	RHEA	34755880
MMDBr0014236	dCTP	Deoxyuridine triphosphate	dCTP deaminase	Deamination	RHEA	34755880
MMDBr0014251	(6R)-5,10-methylene-5,6,7,8-tetrahydrofolic acid	5,10-Methenyltetrahydrofolate	C-1-tetrahydrofolate synthase, cytoplasmic	Synthesis	RHEA	34755880
MMDBr0014313	Acetaldehyde	Acetyl-CoA	Acetaldehyde dehydrogenase	Dehydrogenation	RHEA	34755880
MMDBr0014323	Adenosine triphosphate	ADP	Bifunctional enzyme MurC/Ddl	Ligation	RHEA	34755880
MMDBr0014365	4-Imidazolone-5-propionic acid	Formiminoglutamic acid	Imidazolonepropionase	Non-hydrolytic bond cleavage (or its reversal)	RHEA	34755880
MMDBr0014369	5,10-Methenyltetrahydrofolate	(6S)-10-formyltetrahydrofolic acid	C-1-tetrahydrofolate synthase, cytoplasmic	Reversible cyclization	RHEA	34755880
MMDBr0014407	Argininosuccinic acid	fumarate	Bifunctional protein ArgHA	Non-hydrolytic bond cleavage (or its reversal)	RHEA	34755880
MMDBr0014426	4-Methyl-5-(2-hydroxyethyl)-thiazole	4-methyl-5-(2-phosphooxyethyl)-thiazole	Probable thiamine biosynthetic bifunctional enzyme	Phosphorylation	RHEA	34755880
MMDBr0014472	Adenosine triphosphate	ADP	Cytidine kinase	Phosphorylation	RHEA	34755880
MMDBr0014486	(R)-2,3-Dihydroxy-isovalerate	alpha-Ketoisovaleric acid	Dihydroxy-acid dehydratase, mitochondrial	Hydration/dehydration of C-O bond	RHEA	34755880
MMDBr0014487	(R)-2,3-Dihydroxy-isovalerate	alpha-Ketoisovaleric acid	Dihydroxy-acid dehydratase, mitochondrial	Hydration/dehydration of C-O bond	RHEA	34755880
MMDBr0014514	Adenosine triphosphate	ADP	Cytidylate kinase	Phosphorylation	RHEA	34755880
MMDBr0014559	beta-D-Ribopyranose	beta-D-ribofuranose	L-fucose mutarotase	Mutarotation	RHEA	34755880
MMDBr0017926	Adenosine triphosphate	ADP	CTP synthase	Synthesis	RHEA	34755880
MMDBr0014718	(R)-2,3-Dihydroxy-3-methylpentanoate	2-Keto-3-methyl-valerate	Dihydroxy-acid dehydratase, mitochondrial	Hydration/dehydration of C-O bond	RHEA	34755880
MMDBr0014719	(R)-2,3-Dihydroxy-3-methylpentanoate	2-Keto-3-methyl-valerate	Dihydroxy-acid dehydratase, mitochondrial	Hydration/dehydration of C-O bond	RHEA	34755880
MMDBr0014825	di-trans,octa-cis-undecaprenyl phosphate	di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine	Phospho-N-acetylmuramoyl-pentapeptide-transferase	Transfer of phospho-N-acetylmuramoyl-pentapeptide	RHEA	34755880
MMDBr0014994	Guanosine triphosphate	diphosphate	Phosphoenolpyruvate guanylyltransferase	Transfer of a GMP	RHEA	34755880
MMDBr0017950	aldehydo-D-ribose 5-phosphate	Hydrogen Ion	Pyridoxal 5'-phosphate synthase subunit PDX1	Synthesis	RHEA	34755880
MMDBr0015136	3-Isopropylmalate	2-Isopropylmalic acid	3-isopropylmalate dehydratase large subunit gloJ	Isomerization	RHEA	34755880
MMDBr0015325	Guanosine triphosphate	diphosphate	Molybdenum cofactor guanylyltransferase	Synthesis	RHEA	34755880
MMDBr0016462	(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate	Cyclic pyranopterin monophosphate	Cyclic pyranopterin monophosphate synthase	Synthesis	RHEA	34755880
MMDBr0016907	Adenosine triphosphate	ADP	ATP synthase subunit alpha	ATP hydrolysis; Synthesis	RHEA	34755880
MMDBr0017834	(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate	D-Glyceraldehyde 3-phosphate	Tryptophan synthase	Synthesis	RHEA	34755880
MMDBr0017852	Adenosine triphosphate	ADP	Glutamate--cysteine ligase EgtA	Ligation	RHEA	34755880
MMDBr0017871	(6R)-5,10-methylene-5,6,7,8-tetrahydrofolic acid	(6S)-5,6,7,8-tetrahydrofolic acid	Serine hydroxymethyltransferase	Methylation	RHEA	34755880
MMDBr0017874	Water	L-Glutamic acid	Thermolabile glutaminase	Synthesis	RHEA	34755880
MMDBr0017916	5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide	AICAR	Imidazole glycerol phosphate synthase subunit HisH	Synthesis	RHEA	34755880
MMDBr0024371	Adenosine triphosphate	Hydrogen Ion	Asparagine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024401	L-Serine	Hydrogen Ion	Holo-[acyl-carrier-protein] synthase	Dehydrogenation; Synthesis	RHEA	34755880
MMDBr0024411	Adenosine triphosphate	Hydrogen Ion	Type-2 serine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024415	(S)-4-Amino-5-oxopentanoate	Hydrogen Ion	Glutamyl-tRNA reductase	Reduction	RHEA	34755880
MMDBr0024449	Adenosine triphosphate	diphosphate	Methionine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024454	D-Galactose	Hydrogen Ion	Galactokinase	Phosphorylation	RHEA	34755880
MMDBr0024474	Adenosine triphosphate	diphosphate	Proline--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024483	Water	Hydrogen Ion	Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C	Amide group addition	RHEA	34755880
MMDBr0024539	Hydrogen Ion	5'-Deoxyadenosine	Lipoyl synthase	Synthesis	RHEA	34755880
MMDBr0024568	Water	Hydrogen Ion	Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C	Amide group addition	RHEA	34755880
MMDBr0024590	Adenosine triphosphate	ADP	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0024597	L-Aspartic acid	diphosphate	Aspartate--tRNA(Asp/Asn) ligase	Ligation	RHEA	34755880
MMDBr0024656	Adenosine triphosphate	diphosphate	Arginine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024778	(6S)-10-formyltetrahydrofolic acid	Hydrogen Ion	Methionyl-tRNA formyltransferase	Transfer of a formyl group	RHEA	34755880
MMDBr0024779	Water	formate	Peptide deformylase 1	Removal of the N-terminal formyl group	RHEA	34755880
MMDBr0024813	Dimethylallylpyrophosphate	diphosphate	tRNA dimethylallyltransferase	Transfer of a dimethylallyl group	RHEA	34755880
MMDBr0024833	Tetra-mu3-sulfido-tetrairon(2+)	Water	Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein	Reduction	RHEA	34755880
MMDBr0024967	S-Adenosylmethionine	Hydrogen Ion	tRNA (guanine(37)-N1)-methyltransferase Trm5b	Methylation	RHEA	34755880
MMDBr0025060	Adenosine triphosphate	Hydrogen Ion	Type-2 serine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0025071	S-Adenosylmethionine	S-Adenosylhomocysteine	tRNA (guanine-N(7)-)-methyltransferase	Methylation	RHEA	34755880
MMDBr0025105	S-Adenosylmethionine	Hydrogen Ion	Ribosomal RNA small subunit methyltransferase H	Methylation	RHEA	34755880
MMDBr0025193	Adenosine triphosphate	ADP	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0025258	Adenosine triphosphate	Hydrogen Ion	tRNA-specific 2-thiouridylase MnmA	2-Thiolation of uridine	RHEA	34755880
MMDBr0025514	Acetyl-CoA	Malonyl-CoA	Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha	Carboxylation	RHEA	34755880
MMDBr0025620	L-Cysteine	Hydrogen Ion	Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase	Transfer of the diacylglyceryl group	RHEA	34755880
MMDBr0025650	Hydrogen Ion	Hydrogen Ion	NADH-quinone oxidoreductase subunit C/D	Redox reaction	RHEA	34755880
MMDBr0026022	Adenosine monophosphate	Adenosine	5'-nucleotidase SurE	Hydrolysis of nucleotide; Dephosphorylation	RHEA	34755880
MMDBr0026023	Cytidine monophosphate	Adenosine	5'-nucleotidase SurE	Hydrolysis of nucleotide; Dephosphorylation	RHEA	34755880
MMDBr0026024	Uridine 5'-monophosphate	Uridine	5'-nucleotidase SurE	Hydrolysis of nucleotide; Dephosphorylation	RHEA	34755880
MMDBr0026025	Guanosine monophosphate	Guanosine	5'-nucleotidase SurE	Hydrolysis of nucleotide; Dephosphorylation	RHEA	34755880
MMDBr0026046	Uridine 5'-diphosphate	Uridine triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026047	Uridine 5'-diphosphate	Cytidine triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026048	Guanosine 3',5'-bis(diphosphate)	Guanosine triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026085	Deoxyuridine-5'-diphosphate	Deoxyuridine triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026086	2'-Deoxycytidine 5'-diphosphate	Deoxycytidine 5'-triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026087	2'-Deoxyadenosine 5'-diphosphate	Deoxyadenosine triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026088	2'-Deoxyguanosine 5'-diphosphate	2'-Deoxyguanosine 5'-triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880

Genome Data

Genome Link

Not Available

Genome Length

Not Available

# Predicted Proteins

GenBank Sequence Modification Date

17-FEB-2022

MiMeDB Deposition Date

Reference

PMID: 17704766

Source Links

GenBank