MiMeDB: Showing metabocard for Caffeic acid (MMDBc0000577)

Not Available

Record Information

Version

1.0

Status

Detected and Quantified

Creation Date

2020-12-10 18:50:20 UTC

Update Date

2024-10-09 22:34:05 UTC

Metabolite ID

MMDBc0000577

Metabolite Identification

Common Name

Caffeic acid

Description

Caffeic acid (CAS: 331-39-5) is a polyphenol present in normal human urine positively correlated to coffee consumption and influenced by the dietary intake of diverse types of food (PMID:16870009 ). Caffeic acid has been found to be a microbial metabolite of Escherichia (PMID: 28396925 ).

Structure

MOL 3D MOL SDF 3D SDF PDB 3D PDB SMILES InChI

HEADER    PROTEIN                                 27-SEP-20   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   27-SEP-20         0                                  
HETATM    1  C   UNK     0      -1.625   0.770   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0      -2.958   1.540   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0      -4.292   0.770   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0      -4.292  -0.770   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0      -2.958  -1.540   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0      -1.625  -0.770   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0      -0.291   1.540   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0       1.043   0.770   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0       2.376   1.540   0.000  0.00  0.00           C+0
HETATM   10  O   UNK     0       2.376   3.080   0.000  0.00  0.00           O+0
HETATM   11  O   UNK     0       3.710   0.770   0.000  0.00  0.00           O+0
HETATM   12  O   UNK     0      -5.626   1.540   0.000  0.00  0.00           O+0
HETATM   13  O   UNK     0      -5.626  -1.540   0.000  0.00  0.00           O+0
CONECT    1    2    6    7                                                  
CONECT    2    1    3                                                       
CONECT    3    2    4   12                                                  
CONECT    4    3    5   13                                                  
CONECT    5    4    6                                                       
CONECT    6    5    1                                                       
CONECT    7    1    8                                                       
CONECT    8    7    9                                                       
CONECT    9    8   10   11                                                  
CONECT   10    9                                                            
CONECT   11    9                                                            
CONECT   12    3                                                            
CONECT   13    4                                                            
MASTER        0    0    0    0    0    0    0    0   13    0   26    0
END

Synonyms

Value	Source
3,4-Dihydroxy-trans-cinnamate	ChEBI
3,4-Dihydroxycinnamic acid	ChEBI
trans-Caffeate	ChEBI
3,4-Dihydroxy-trans-cinnamic acid	Generator
3,4-Dihydroxycinnamate	Generator
Caffeate	Generator
Caffeic acid, monosodium salt	HMDB
Caffeic acid, (e)-isomer	HMDB
Sodium caffeate	HMDB
(2E)-(3,4-Dihydroxyphenyl)-2-propenoic acid	HMDB
(2E)-3-(3,4-Dihydroxyphenyl)-2-propenoic acid	HMDB
(e)-3,4-Dihydroxycinnamic acid	HMDB
(e)-3-(3,4-Dihydroxyphenyl)-2-propenoic acid	HMDB
(e)-3-(3,4-Dihydroxyphenyl)acrylic acid	HMDB
(e)-Caffeic acid	HMDB
3,4-Dihydroxybenzeneacrylic acid	HMDB
3-(3,4-Dihydroxyphenyl)-2-propenoic acid	HMDB
3-(3,4-Dihydroxyphenyl)propenoic acid	HMDB
4-(2'-Carboxyvinyl)-1,2-dihydroxybenzene	HMDB
4-(2-Carboxyethenyl)-1,2-dihydroxybenzene	HMDB
4-(2’-carboxyvinyl)-1,2-dihydroxybenzene	HMDB
DHCA	HMDB
trans-3,4-Dihydroxycinnamic acid	HMDB
Caffeic acid	HMDB
3',4'-Dihydroxycinnamic acid	HMDB
(2E)-3-(3,4-Dihydroxyphenyl)prop-2-enoic acid;	HMDB

Molecular Formula

C₉H₈O₄

Average Mass

180.1574

Monoisotopic Mass

180.042258744

IUPAC Name

(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoic acid

Traditional Name

caffeic acid

CAS Registry Number

Not Available

SMILES

OC(=O)\C=C\C1=CC(O)=C(O)C=C1

InChI Identifier

InChI=1S/C9H8O4/c10-7-3-1-6(5-8(7)11)2-4-9(12)13/h1-5,10-11H,(H,12,13)/b4-2+

InChI Key

QAIPRVGONGVQAS-DUXPYHPUSA-N

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as hydroxycinnamic acids. Hydroxycinnamic acids are compounds containing an cinnamic acid where the benzene ring is hydroxylated.

Kingdom

Organic compounds

Super Class

Phenylpropanoids and polyketides

Class

Cinnamic acids and derivatives

Sub Class

Hydroxycinnamic acids and derivatives

Direct Parent

Hydroxycinnamic acids

Alternative Parents

Substituents

Cinnamic acid
Coumaric acid or derivatives
Hydroxycinnamic acid
Catechol
Styrene
1-hydroxy-4-unsubstituted benzenoid
1-hydroxy-2-unsubstituted benzenoid
Phenol
Monocyclic benzene moiety
Benzenoid
Carboxylic acid derivative
Carboxylic acid
Monocarboxylic acid or derivatives
Organic oxide
Organic oxygen compound
Hydrocarbon derivative
Organooxygen compound
Carbonyl group
Aromatic homomonocyclic compound

Molecular Framework

Aromatic homomonocyclic compounds

External Descriptors

caffeic acid (CHEBI:16433 )
Caffeate derivatives (C01197 )

Functional Ontology

Not Available

Physical Properties

State

Expected Solid

Predicted Properties

Property	Value	Source
Water Solubility	1.61 g/L	ALOGPS
logP	1.67	ALOGPS
logP	1.53	ChemAxon
logS	-2	ALOGPS
pKa (Strongest Acidic)	3.64	ChemAxon
pKa (Strongest Basic)	-6.3	ChemAxon
Physiological Charge	-1	ChemAxon
Hydrogen Acceptor Count	4	ChemAxon
Hydrogen Donor Count	3	ChemAxon
Polar Surface Area	77.76 Å²	ChemAxon
Rotatable Bond Count	2	ChemAxon
Refractivity	47.02 m³·mol⁻¹	ChemAxon
Polarizability	17.34 Å³	ChemAxon
Number of Rings	1	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	Yes	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

Spectra

Spectrum Type	Description	Splash Key	Deposition Date	View
GC-MS	GC-MS Spectrum - GC-MS (3 TMS)	splash10-014i-1593000000-b24e97b50ed1f50252f3	2014-06-16	View Spectrum
GC-MS	GC-MS Spectrum - EI-B (Non-derivatized)	splash10-001i-9800000000-bae43e98e22babcbf5a7	2017-09-12	View Spectrum
GC-MS	GC-MS Spectrum - EI-B (Non-derivatized)	splash10-000i-9600000000-6140146b8e32bda5e3c9	2017-09-12	View Spectrum
GC-MS	GC-MS Spectrum - GC-EI-TOF (Non-derivatized)	splash10-014i-0593000000-16610dfa8ac4ac67a4c2	2017-09-12	View Spectrum
GC-MS	GC-MS Spectrum - GC-MS (Non-derivatized)	splash10-014i-1593000000-b24e97b50ed1f50252f3	2017-09-12	View Spectrum
GC-MS	GC-MS Spectrum - GC-EI-TOF (Non-derivatized)	splash10-014i-0592000000-1bb03bc99be6718d247e	2017-09-12	View Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive	splash10-001i-1900000000-6a963e50b910f05b6825	2016-09-22	View Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (3 TMS) - 70eV, Positive	splash10-00e9-5039000000-d55c6a31e04536d33b58	2017-10-06	View Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive	Not Available	2021-10-12	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - 20V, Negative	splash10-000i-0900000000-90ad608487db4c112469	2021-09-20	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - 20V, Negative	splash10-001i-0900000000-dcc07d9a43defb5683a0	2021-09-20	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - 10V, Negative	splash10-000i-0900000000-762c7a39be8e2819bc51	2021-09-20	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - 40V, Negative	splash10-0019-4900000000-e716811ee5cf56acce9e	2021-09-20	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - 10V, Negative	splash10-000i-0900000000-037f59c6ff1daadca2a0	2021-09-20	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - 40V, Negative	splash10-0019-6900000000-a67fe3c28be25c2fa72b	2021-09-20	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - 30V, Negative	splash10-0019-1900000000-62d755ec157c381054b3	2021-09-20	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - 10V, Negative	splash10-000i-0900000000-6c93facd0d3caabc67f1	2021-09-20	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - 40V, Negative	splash10-001r-0900000000-7b2d4553b6a25b853d4b	2021-09-20	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - 20V, Negative	splash10-000i-0900000000-3ed879b5217c5d703cd5	2021-09-20	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - 20V, Negative	splash10-000i-0900000000-bddc5a2872c93f7185ba	2021-09-20	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - 40V, Negative	splash10-000i-9600000000-376ae5146fc0f93c9ff5	2021-09-20	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - 10V, Negative	splash10-004i-0900000000-7d707e3512f8df7d6c53	2021-09-20	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - 35V, Negative	splash10-000i-0900000000-c904417e68f103c0c963	2021-09-20	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - DI-ESI-qTof , Positive	splash10-03di-0900000000-f31bbdf32d6b72a381e7	2017-09-14	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - 40V, Positive	splash10-000i-9000000000-ad7b879926d9c809f9c8	2021-09-20	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - 35V, Positive	splash10-014s-1900000000-d3c79213f8f23833fadc	2021-09-20	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - 10V, Positive	splash10-03di-0900000000-3adb4dbfdaeb614b61e6	2021-09-20	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - 40V, Positive	splash10-000i-9000000000-8f7413c3605b29515931	2021-09-20	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - 20V, Positive	splash10-03di-2900000000-467621cde3e4486ad6bf	2021-09-20	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - 30V, Positive	splash10-014i-0900000000-7fdae010c3ffe7ab1156	2021-09-20	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - 50V, Positive	splash10-000i-9000000000-a67e2178525a89f45da9	2021-09-20	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - 10V, Positive	splash10-03di-0900000000-8407d64b83bf427de33f	2021-09-20	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - 10V, Positive	splash10-03dr-0900000000-91200c128446226f6ecb	2021-09-20	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum - 10V, Positive	splash10-03di-0900000000-2ec4b8c30dbd96e11228	2021-09-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 100 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 1000 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 200 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 300 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 400 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 500 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 600 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 700 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 800 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 900 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)		2022-08-20	View Spectrum

Biological Properties

Cellular Locations

Not Available

Biospecimen Locations

Blood
Epidermis
Feces
Platelet
Prostate
Urine

Tissue Locations

Epidermis
Platelet
Prostate

Associated OMIM IDs

114500 (Colorectal cancer)
610247 (Eosinophilic esophagitis)

Human Proteins and Enzymes

Protein ID	Protein Name	Protein Type	Uniprot ID	Species
MMDBp0192584	Arachidonate 5-lipoxygenase	Unknown	P09917	Homo sapiens

Human Pathways

Pathways

Name	SMPDB/PathBank

Metabolic Reactions

Reactions

Reaction ID	Precursor	Product	Enzyme	Reaction Type	Data Source	Reference
MMDBr0002192	4-Hydroxycinnamic acid	Caffeic acid	tyrosinase		VMH	30371894

Multistep Reactions

Reaction ID	Precursor	Product	Enzyme	Reaction Type	Data Source	Reference
MMDBr0012791	Caffeic acid	3,4-Dihydroxyhydrocinnamic acid	Not Available	multistep reaction by bacteria		30409649
MMDBr0012793	3,4-Dihydroxyhydrocinnamic acid	Dihydrocaffeic acid 3-sulfate	Not Available	conjugation; phase-II biotransformation; sulfate-conjugation		Manually annotated by MiMeDB team

Reaction ID	Precursor	Product	Enzyme	Reaction Type	Data Source	Reference
MMDBr0012791	Caffeic acid	3,4-Dihydroxyhydrocinnamic acid	Not Available	multistep reaction by bacteria		30409649
MMDBr0012794	3,4-Dihydroxyhydrocinnamic acid	Dihydrocaffeic acid 3-O-glucuronide	Not Available	conjugation; phase-II biotransformation; glucuronide-conjugation		Manually annotated by MiMeDB team

Health Effects and Bioactivity

Health Outcome/Bioactivity	Metabolite Response/Effect	Evidence Type	Host and Biospecimen	Data Source	Reference
Colorectal cancer		Association	Human feces	HMDB	27275383
Colorectal cancer		Association	Human feces	HMDB	25037050
Colorectal cancer		Association	Human feces	HMDB	27015276
Antioxidant		Chemical reaction		PubMed	11768243
Anti-atherogenic		Animal_model		PubMed	16806235
Anti-inflammatory		Animal_model		PubMed	16806235
Traumatic brain injury	reduces	Animal_model	brain	PubMed	17074364
5-lipoxygenase	inhibitor	Animal_model	brain	PubMed	18482095
Traumatic brain injury	reduces	Animal_model		PubMed	18482095
Anti-inflammatory		Animal_model	skin	PubMed	22036979
Antioxidant		Animal_model	skin	PubMed	22036979
Dipeptidyl peptidase-iv	inhibits			PubMed	28230764
Glucose uptake	increases	Cell culture	3T3-L1 adipocytes	PubMed	28230764
Free radical scavenger		Chemical reaction		Pubchem	28415050

Microbial Sources

Superkingdom/Kingdom	Phylum	Total species	Hosts and Body Sites	Microbial Links
Bacteria	Firmicutes	2	Human ; Human feces	Indirect association between microbiota composition and metabolites measured in host biospecimen
Eukaryota/Fungi	Ascomycota	1	Human feces; Human saliva	Unknown

Exposure Sources

Source Type	Source Sub-type	Species	Data Source	Reference
Animal		Haliotis	FooDB	Manually Annotated
Animal		Strombidae	FooDB	Manually Annotated
Animal		Clupea harengus harengus	FooDB	Manually Annotated
Animal		Undaria pinnatifida	FooDB	Manually Annotated
Animal		Peprilus triacanthus	FooDB	Manually Annotated
Animal		Rhodophyta	FooDB	Manually Annotated
Animal		Myoxocephalus	FooDB	Manually Annotated
Animal		Eucheuma	FooDB	Manually Annotated
Animal		Saccharina japonica	FooDB	Manually Annotated
Animal		Spirulina	FooDB	Manually Annotated
Animal		Lota lota	FooDB	Manually Annotated
Animal		Porphyra umbilicalis	FooDB	Manually Annotated
Animal		Chondrus crispus	FooDB	Manually Annotated
Animal	Milk	Bos taurus	FooDB	28306241
Animal		Laminaria	FooDB	Manually Annotated
Food	Cocoa products	Theobroma cacao	FooDB	Phenol Explorer
Food			FooDB	Dominik Szwajgier. Content of Individual Phenolic Acids in Worts and Beers and their Possible Contribution to the Antiradical Activity of Beer. J. Inst. Brew. 115(3), 2009, 243
Food			FooDB	Phenol Explorer
Food			FooDB	19640966
Food		Coffea arabica	FooDB	Phenol Explorer
Food		Coffea arabica	FooDB	Phenol Explorer
Food		Coffea canephora	FooDB	Phenol Explorer
Food		Coffea canephora	FooDB	Phenol Explorer
Food		Coffea arabica	FooDB	Phenol Explorer
Food		Coffea canephora	FooDB	Phenol Explorer
Food			FooDB	D. KOMES et al. Study of phenolic and volatile composition of white wine during fermentation. Vitis 46 (2), 77-84 (2007)
Food			FooDB	Phenol Explorer
Food			FooDB	Phenol Explorer
Food			FooDB	Phenol Explorer
Food			FooDB	Phenol Explorer
Food	Beer	Barley	FooDB	Not Available
Food			FooDB	Phenol Explorer
Food			FooDB	Manually Annotated
Food			FooDB	Phenol Explorer
Food			FooDB	12617582
Plant	Fruit	Sesamum orientale	FooDB	DUKE
Plant		Vaccinium elliottii	FooDB	Manually Annotated
Plant	Fruit	Laurus nobilis	FooDB	DUKE
Plant		Ziziphus zizyphus	FooDB	Manually Annotated
Plant		Tilia tomentosa	FooDB	Phenol Explorer
Plant		Dimocarpus longan	FooDB	Manually Annotated
Plant		Citrus aurantiifolia	FooDB	Manually Annotated
Plant		Salvia hispanica	FooDB	Manually Annotated
Plant	Oil	Olea europaea	FooDB	Phenol Explorer
Plant	Fruit	Pyrus communis	FooDB	Phenol Explorer
Plant		Cynara cardunculus	FooDB	Manually Annotated
Plant		Vitellaria paradoxa	FooDB	Manually Annotated
Plant	Fruit	Vaccinium angustifolium x vaccinium corymbosum	FooDB	Phenol Explorer
Plant		Pangium edule	FooDB	Manually Annotated
Plant		Capsicum annuum	FooDB	Manually Annotated
Plant		Solanum lycopersicum	FooDB	Manually Annotated
Plant		Pistacia vera	FooDB	Manually Annotated
Plant		Allium	FooDB	Manually Annotated
Plant		Brassica oleracea var. viridis	FooDB	Manually Annotated
Plant		Capsicum annuum	FooDB	Manually Annotated
Plant	Plant	Vaccinium corymbosum	FooDB	DUKE
Plant		Agave	FooDB	Manually Annotated
Plant	Seed	Arachis hypogaea	FooDB	DUKE
Plant		Hedysarum alpinum	FooDB	Manually Annotated
Plant		Diospyros	FooDB	Manually Annotated
Plant		Vigna aconitifolia	FooDB	Manually Annotated
Plant		Cuminum cyminum	FooDB	Phenol Explorer
Plant		Amaranthus	FooDB	Manually Annotated
Plant		Mammea americana	FooDB	Manually Annotated
Plant		Cuminum cyminum	FooDB	Phenol Explorer
Plant		Gossypium	FooDB	Manually Annotated
Plant		Brassica alboglabra	FooDB	Manually Annotated
Plant		Beta vulgaris	FooDB	Manually Annotated
Plant	Plant	Rosmarinus officinalis	FooDB	DUKE
Plant		Annona squamosa	FooDB	Manually Annotated
Plant		Apium graveolens var. dulce	FooDB	Manually Annotated
Plant	Fruit	Rubus idaeus	FooDB	Phenol Explorer
Plant	Fruit	Rubus idaeus	FooDB	Phenol Explorer
Plant		Vitis	FooDB	Manually Annotated
Plant		Xanthosoma sagittifolium	FooDB	Manually Annotated
Plant	Fruit	Coriandrum sativum	FooDB	DUKE
Plant	Fruit	Citrus sinensis	FooDB	DUKE
Plant		Basella alba	FooDB	Manually Annotated
Plant		Capsicum baccatum var. baccatum	FooDB	Manually Annotated
Plant		Citrus latifolia	FooDB	Manually Annotated
Plant	Plant	Armoracia rusticana	FooDB	DUKE
Plant		Hyssopus officinalis	FooDB	Phenol Explorer
Plant		Carya illinoinensis	FooDB	Manually Annotated
Plant	Plant	Melissa officinalis	FooDB	DUKE
Plant		Byrsonima crassifolia	FooDB	Manually Annotated
Plant		Allium cepa	FooDB	Manually Annotated
Plant	Fruit	Vaccinium corymbosum	FooDB	S.Hakkinen, M. Heinonen, S. Karenlampi, H. Mykkanen, J. Ruuskanen, R. Torronen. Screening of selected flavonoids and phenolic acids in 19 berries. Food Research International 32 (1999) 345-353. https://www.sciencedirect.com/science/article/pii/S0963996999000952
Plant	Leaves	Carica papaya	FooDB	DUKE
Plant		Capsicum pubescens	FooDB	Manually Annotated
Plant		Allium cepa	FooDB	Manually Annotated
Plant		Crateva religiosa	FooDB	Manually Annotated
Plant		Vitis aestivalis	FooDB	Manually Annotated
Plant		Eugenia javanica	FooDB	Manually Annotated
Plant			FooDB	Manually Annotated
Plant		Mentha arvensis	FooDB	Manually Annotated
Plant		Brassica rapa var. chinensis	FooDB	Manually Annotated
Plant		Cinnamomum aromaticum	FooDB	Manually Annotated
Plant		Vaccinium stamineum	FooDB	Manually Annotated
Plant	Leaves	Juglans regia	FooDB	DUKE
Plant		Chenopodium album	FooDB	Manually Annotated
Plant		Cucurbita maxima	FooDB	Manually Annotated
Plant	Fruit	Vaccinium macrocarpon	FooDB	Phenol Explorer
Plant		Psophocarpus tetragonolobus	FooDB	Manually Annotated
Plant		Thymus vulgaris	FooDB	Phenol Explorer
Plant	Fruit	Vaccinium macrocarpon	FooDB	Phenol Explorer
Plant	Leaves	Brassica oleracea var. italica	FooDB	DUKE
Plant		Thymus vulgaris	FooDB	Phenol Explorer
Plant	Leaves	Origanum majorana	FooDB	DUKE
Plant		Allium ampeloprasum	FooDB	Manually Annotated
Plant		Sechium edule	FooDB	Manually Annotated
Plant		Olea europaea	FooDB	PhytoHub
Plant		Brassica oleracea	FooDB	Manually Annotated
Plant		Rubus	FooDB	PhytoHub
Plant		Grataegosorbus mitschurinii	FooDB	Manually Annotated
Plant	Fruit juice	Punica granatum	FooDB	DUKE
Plant		Fragaria x ananassa	FooDB	PhytoHub
Plant		Diospyros virginiana	FooDB	Manually Annotated
Plant	Leaves	Moringa oleifera	FooDB	DUKE
Plant		Allium sativum	FooDB	Manually Annotated
Plant		Rubus x loganobaccus	FooDB	Manually Annotated
Plant		Tragopogon porrifolius	FooDB	Manually Annotated
Plant		Thymus vulgaris	FooDB	Phenol Explorer
Plant	Juice	Malus pumila	FooDB	Phenol Explorer
Plant		Allium sativum	FooDB	Manually Annotated
Plant		Rumex	FooDB	Manually Annotated
Plant		Allium ascalonicum	FooDB	Manually Annotated
Plant	Fruit	Rubus idaeus	FooDB	S.Hakkinen, M. Heinonen, S. Karenlampi, H. Mykkanen, J. Ruuskanen, R. Torronen. Screening of selected flavonoids and phenolic acids in 19 berries. Food Research International 32 (1999) 345-353. https://www.sciencedirect.com/science/article/pii/S0963996999000952
Plant	Peel	Pyrus communis	FooDB	18778075
Plant		Citrullus lanatus var. fistulosus	FooDB	Manually Annotated
Plant	Seed meal	Helianthus annuus	FooDB	Phenol Explorer
Plant	Juice	Pyrus communis	FooDB	Dilek Tanrioven and Aziz Eksi. Phenolic compounds in pear juice from different cultivars. Food Chemistry. 2005, 93(1), 89-93
Plant		Amelanchier alnifolia	FooDB	Manually Annotated
Plant		Eugenia uniflora	FooDB	Manually Annotated
Plant		Illicium verum	FooDB	Phenol Explorer
Plant	Juice	Hippophae rhamnoides	FooDB	Phenol Explorer
Plant		Annona reticulata	FooDB	Manually Annotated
Plant	Juice	Pyrus communis	FooDB	Dilek Tanrioven and Aziz Eksi. Phenolic compounds in pear juice from different cultivars. Food Chemistry. 2005, 93(1), 89-93
Plant		Sesbania bispinosa	FooDB	Manually Annotated
Plant	Juice	Pyrus communis	FooDB	Dilek Tanrioven and Aziz Eksi. Phenolic compounds in pear juice from different cultivars. Food Chemistry. 2005, 93(1), 89-93
Plant		Ribes x nidigrolaria	FooDB	Manually Annotated
Plant		Melissa officinalis	FooDB	Phenol Explorer
Plant		Solanum lycopersicum	FooDB	PhytoHub
Plant	Juice	Malus pumila	FooDB	Phenol Explorer
Plant		Garcinia mangostana	FooDB	Manually Annotated
Plant	Juice	Pyrus communis	FooDB	Dilek Tanrioven and Aziz Eksi. Phenolic compounds in pear juice from different cultivars. Food Chemistry. 2005, 93(1), 89-93
Plant		Lathyrus sativus	FooDB	Manually Annotated
Plant		Dioscorea pentaphylla	FooDB	Manually Annotated
Plant		Allium tuberosum	FooDB	Manually Annotated
Plant		Corchorus olitorius	FooDB	Manually Annotated
Plant	Plant	Chamaemelum nobile	FooDB	DUKE
Plant		Brassica oleracea var. italica	FooDB	9416471
Plant	Plant	Prunus domestica	FooDB	DUKE
Plant		Foeniculum vulgare	FooDB	Phenol Explorer
Plant	Juice	Malus pumila	FooDB	Phenol Explorer
Plant		Mentha spicata	FooDB	Phenol Explorer
Plant	Fruit	Vaccinium corymbosum	FooDB	Phenol Explorer
Plant		Mentha spicata	FooDB	Phenol Explorer
Plant		Petasites japonicus	FooDB	Manually Annotated
Plant	Fruit	Vaccinium corymbosum	FooDB	Phenol Explorer
Plant		Pyrus communis	FooDB	PhytoHub
Plant	Plant	Pisum sativum	FooDB	DUKE
Plant		Prunus tomentosa	FooDB	Manually Annotated
Plant	Tuber	Solanum tuberosum	FooDB	DUKE
Plant		Maranta arundinacea	FooDB	Manually Annotated
Plant		Matteuccia struthiopteris	FooDB	Manually Annotated
Plant		Cucurbita moschata	FooDB	Manually Annotated
Plant		Macadamia	FooDB	Manually Annotated
Plant		Laurus nobilis	FooDB	Phenol Explorer
Plant		Brassica oleracea var. italica	FooDB	Fernando Vallejo, F A Tomas-Barberan, C Garcia-Viguera. Potential bioactive compounds in health promotion from broccoli cultivars grown in Spain. J Sci Food Agric, 2002, 82(11):1293-1297
Plant	Fruit	Phoenix dactylifera	FooDB	Phenol Explorer
Plant		Origanum majorana	FooDB	Phenol Explorer
Plant		Vaccinium myrtilloides	FooDB	Manually Annotated
Plant	Seed	Juglans regia	FooDB	DUKE
Plant		Origanum majorana	FooDB	Phenol Explorer
Plant	Plant	Sambucus nigra	FooDB	DUKE
Plant	Juice	Malus pumila	FooDB	Phenol Explorer
Plant		Papaver	FooDB	Manually Annotated
Plant	Root	Daucus carota ssp. sativus	FooDB	Phenol Explorer
Plant	Juice	Punica granatum	FooDB	Phenol Explorer
Plant		Rosa	FooDB	Manually Annotated
Plant	Fruit	Solanum melongena	FooDB	DUKE
Plant		Nelumbo	FooDB	Manually Annotated
Plant		Apium graveolens var. rapaceum	FooDB	Manually Annotated
Plant	Fruit	Ananas comosus	FooDB	DUKE
Plant	Root	Daucus carota ssp. sativus	FooDB	Phenol Explorer
Plant	Fruit	Prunus domestica	FooDB	Phenol Explorer
Plant		Brassica oleracea var. conica	FooDB	Manually Annotated
Plant	Flower	Taraxacum officinale	FooDB	DUKE
Plant	Plant	Camellia sinensis	FooDB	DUKE
Plant	Fruit	Prunus domestica	FooDB	Phenol Explorer
Plant		Annona cherimola	FooDB	Manually Annotated
Plant		Lippia graveolens	FooDB	Manually Annotated
Plant	Seed	Glycine max	FooDB	DUKE
Plant		Brassica rapa var. pekinensis	FooDB	Manually Annotated
Plant		Brassica rapa	FooDB	Manually Annotated
Plant		Rosmarinus officinalis	FooDB	Phenol Explorer
Plant	Fruit	Malus pumila	FooDB	Phenol Explorer
Plant	Bulb	Allium sativum l. var. sativum	FooDB	DUKE
Plant		Prunus	FooDB	Manually Annotated
Plant		Rosmarinus officinalis	FooDB	Phenol Explorer
Plant	Fruit	Vaccinium angustifolium	FooDB	Phenol Explorer
Plant	Testa	Juglans regia	FooDB	DUKE
Plant		Capparis spinosa	FooDB	Manually Annotated
Plant	Root	Zingiber officinale	FooDB	Phenol Explorer
Plant	Root	Ipomoea batatas	FooDB	DUKE
Plant	Leaves	Apium graveolens	FooDB	DUKE
Plant	Fruit	Vaccinium corymbosum	FooDB	Phenol Explorer
Plant		Lens culinaris	FooDB	Manually Annotated
Plant	Fruit	Persea americana	FooDB	DUKE
Plant	Fruit	Ribes nigrum	FooDB	DUKE
Plant	Plant	Matricaria recutita	FooDB	DUKE
Plant		Phaseolus lunatus	FooDB	Manually Annotated
Plant		Artocarpus heterophyllus	FooDB	Manually Annotated
Plant	Plant	Prunus armeniaca	FooDB	DUKE
Plant	Fruit	Malus pumila	FooDB	Phenol Explorer
Plant		Prunus virginiana	FooDB	Manually Annotated
Plant	Fruit	Malus pumila	FooDB	Phenol Explorer
Plant	Fruit	Prunus domestica	FooDB	Phenol Explorer
Plant	Fruit	Phoenix dactylifera	FooDB	Phenol Explorer
Plant	Root	Arctium lappa	FooDB	DUKE
Plant	Fruit	Vaccinium corymbosum	FooDB	Sellappan S, Akoh CC, Krewer G. Phenolic Compounds and Antioxidant Capacity of Georgia-Grown Blueberries and Blackberries. 2002. J. Agric. Food Chem. 2002, 50, 2432-2438
Plant	Leaves	Cichorium intybus	FooDB	DUKE
Plant		Musa acuminata	FooDB	Manually Annotated
Plant		Vigna unguiculata ssp. unguiculata	FooDB	Manually Annotated
Plant		Macadamia tetraphylla	FooDB	Manually Annotated
Plant		Cucurbita pepo var. cylindrica	FooDB	Manually Annotated
Plant		Linum usitatissimum	FooDB	Manually Annotated
Plant	Root	Levisticum officinale	FooDB	DUKE
Plant		Cucurbita pepo var. cylindrica	FooDB	Manually Annotated
Plant		Lagenaria siceraria	FooDB	Manually Annotated
Plant	Fruit	Phaseolus vulgaris	FooDB	DUKE
Plant	Fruit	Persea americana	FooDB	F. W. Knapp. Some Characteristics of Eggplant and Avocado Poiyphenolases. J. Food Science. 30(6), 930-936, 1965
Plant		Carissa macrocarpa	FooDB	Manually Annotated
Plant		Phyllostachys edulis	FooDB	Manually Annotated
Plant		Satureja hortensis	FooDB	Manually Annotated
Plant		Citrus reticulata	FooDB	Manually Annotated
Plant		Averrhoa carambola	FooDB	Manually Annotated
Plant	Juice	Prunus domestica	FooDB	Phenol Explorer
Plant		Sorbus aucuparia	FooDB	Manually Annotated
Plant	Juice	Citrus sinensis	FooDB	Phenol Explorer
Plant	Juice	Prunus domestica	FooDB	Phenol Explorer
Plant	Fruit	Prunus armeniaca	FooDB	Phenol Explorer
Plant		Nelumbo nucifera	FooDB	Manually Annotated
Plant		Brassica oleracea var. costata	FooDB	Manually Annotated
Plant	Fruit	Vaccinium myrtillus	FooDB	DUKE
Plant		Panax	FooDB	Manually Annotated
Plant	Juice	Citrus sinensis	FooDB	Phenol Explorer
Plant		Bertholletia excelsa	FooDB	Manually Annotated
Plant	Fruit	Solanum lycopersicum var. cerasiforme	FooDB	Phenol Explorer
Plant		Ceratonia siliqua	FooDB	Manually Annotated
Plant	Seed	Pimpinella anisum	FooDB	DUKE
Plant		Cymbopogon citratus	FooDB	Manually Annotated
Plant		Luffa aegyptiaca	FooDB	Manually Annotated
Plant		Matricaria recutita	FooDB	Phenol Explorer
Plant		Rosmarinus officinalis	FooDB	Phenol Explorer
Plant		Vigna umbellata	FooDB	Manually Annotated
Plant		Carthamus tinctorius	FooDB	Manually Annotated
Plant	Leaves	Artemisia dracunculus	FooDB	DUKE
Plant	Seed	Trigonella foenum-graecum	FooDB	Phenol Explorer
Plant		Cicer arietinum	FooDB	Manually Annotated
Plant		Allium fistulosum	FooDB	Manually Annotated
Plant	Plant	Prunus cerasus	FooDB	DUKE
Plant		Capsicum	FooDB	Manually Annotated
Plant		Lupinus	FooDB	Manually Annotated
Plant	Leaves	Ocimum basilicum	FooDB	DUKE
Plant		Anacardium occidentale	FooDB	Manually Annotated
Plant		Tilia cordata	FooDB	Manually Annotated
Plant		Vaccinium alaskaense	FooDB	Manually Annotated
Plant	Juice	Citrus sinensis	FooDB	Phenol Explorer
Plant		Brassica oleracea var. botrytis	FooDB	Phenol Explorer
Plant	Juice	Citrus sinensis	FooDB	Phenol Explorer
Plant		Prunus persica var. nucipersica	FooDB	Manually Annotated
Plant	Seed	Juglans nigra	FooDB	DUKE
Plant		Durio zibethinus	FooDB	Manually Annotated
Plant		Trigonella foenum-graecum	FooDB	Phenol Explorer
Plant		Vaccinium macrocarpon	FooDB	PhytoHub
Plant		Brassica napus var. pabularia	FooDB	Manually Annotated
Plant		Ribes glandulosum	FooDB	Manually Annotated
Plant		Diospyros kaki	FooDB	Manually Annotated
Plant		Origanum x majoricum	FooDB	Phenol Explorer
Plant		Virola surinamensis	FooDB	Manually Annotated
Plant		Rumex acetosa	FooDB	Manually Annotated
Plant		Pimpinella anisum	FooDB	Phenol Explorer
Plant		Aloysia triphylla	FooDB	Manually Annotated
Plant		Pyrus pyrifolia	FooDB	Manually Annotated
Plant	Nut	Juglans regia	FooDB	Phenol Explorer
Plant		Capsicum chinense	FooDB	Manually Annotated
Plant	Fruit	Elettaria cardamomum	FooDB	DUKE
Plant	Fruit	Prunus cerasus	FooDB	Phenol Explorer
Plant	Fruit	Pyrus communis	FooDB	A. Escarpa and M. C. Gonzalez. Evaluation of High-Performance Liquid Chromatography for Determination of Phenolic Compounds in Pear Horticultural Cultivars. Chromatographia Vol. 51, No. 1/2, January 2000, 37-43
Plant		Vaccinium reticulatum	FooDB	Manually Annotated
Plant		Solanum quitoense	FooDB	Manually Annotated
Plant		Theobroma grandiflorum	FooDB	Manually Annotated
Plant		Cinnamomum verum	FooDB	Phenol Explorer
Plant	Rhizome	Curcuma longa	FooDB	DUKE
Plant		Ginkgo biloba	FooDB	Manually Annotated
Plant	Fruit	Solanum melongena	FooDB	Phenol Explorer
Plant		Vigna unguiculata ssp. cylindrica	FooDB	Manually Annotated
Plant		Flammulina velutipes	FooDB	Manually Annotated
Plant	Fruit	Solanum melongena	FooDB	Phenol Explorer
Plant			FooDB	Manually Annotated
Plant		Anethum graveolens	FooDB	Phenol Explorer
Plant		Citrus japonica	FooDB	Manually Annotated
Plant		Perideridia oregana	FooDB	Manually Annotated
Plant	Juice	Pyrus communis	FooDB	Dilek Tanrioven and Aziz Eksi. Phenolic compounds in pear juice from different cultivars. Food Chemistry. 2005, 93(1), 89-93
Plant		Pastinaca sativa	FooDB	Manually Annotated
Plant		Vaccinium arboreum	FooDB	Manually Annotated
Plant		Pastinaca sativa	FooDB	Manually Annotated
Plant		Pouteria sapota	FooDB	Manually Annotated
Plant		Wasabia japonica	FooDB	Manually Annotated
Plant		Origanum onites	FooDB	Manually Annotated
Plant	Juice	Pyrus communis	FooDB	Dilek Tanrioven and Aziz Eksi. Phenolic compounds in pear juice from different cultivars. Food Chemistry. 2005, 93(1), 89-93
Plant	Fruit	Vitis vinifera	FooDB	DUKE
Plant	Fruit	Ribes nigrum	FooDB	S.Hakkinen, M. Heinonen, S. Karenlampi, H. Mykkanen, J. Ruuskanen, R. Torronen. Screening of selected flavonoids and phenolic acids in 19 berries. Food Research International 32 (1999) 345-353. https://www.sciencedirect.com/science/article/pii/S0963996999000952
Plant		Eragrostis tef	FooDB	Manually Annotated
Plant		Viburnum edule	FooDB	Manually Annotated
Plant		Cucumis sativus	FooDB	Manually Annotated
Plant	Peel	Pyrus communis	FooDB	18778075
Plant		Coriandrum sativum	FooDB	Phenol Explorer
Plant		Cucumis sativus	FooDB	Manually Annotated
Plant	Plant	Portulaca oleracea	FooDB	DUKE
Plant	Fruit	Solanum melongena	FooDB	Mohamed Hassas Roudsari, Alice Signoret, Jean Crouzet. Eggplant polyphenol oxidase: Purification, characterisation and properties. Food Chemistry, 7(3), November 1981, 227-238
Plant		Dioscorea	FooDB	Manually Annotated
Plant	Peel	Pyrus communis	FooDB	A. Escarpa and M. C. Gonzalez. Evaluation of High-Performance Liquid Chromatography for Determination of Phenolic Compounds in Pear Horticultural Cultivars. Chromatographia Vol. 51, No. 1/2, January 2000, 37-43
Plant	Fruit	Solanum lycopersicum var. lycopersicum	FooDB	DUKE
Plant		Momordica charantia	FooDB	Manually Annotated
Plant	Fruit	Rubus	FooDB	Sellappan S, Akoh CC, Krewer G. Phenolic Compounds and Antioxidant Capacity of Georgia-Grown Blueberries and Blackberries. 2002. J. Agric. Food Chem. 2002, 50, 2432-2438
Plant	Leaves	Allium schoenoprasum	FooDB	DUKE
Plant	Seed	Citrullus lanatus	FooDB	DUKE
Plant		Rubus ursinus x idaeus	FooDB	Manually Annotated
Plant		Coriandrum sativum	FooDB	Phenol Explorer
Plant	Shoot	Asparagus officinalis	FooDB	Miller, H. G.; Ikawa, M.; Peirce, L. C. 1991: Caffeic acid identified as an inhibitory compound in asparagus root filtrate. Hortscience 26: 1525-1527.
Plant		Castanea	FooDB	Manually Annotated
Plant		Pleurotus ostreatus	FooDB	Manually Annotated
Plant	Fruit	Piper nigrum	FooDB	DUKE
Plant	Bark	Cinnamomum verum	FooDB	DUKE
Plant		Cirsium	FooDB	Manually Annotated
Plant		Opuntia	FooDB	Manually Annotated
Plant		Raphanus sativus var. sativus	FooDB	Manually Annotated
Plant		Colocasia esculenta	FooDB	Manually Annotated
Plant		Lactuca sativa l. var. longifolia	FooDB	Manually Annotated
Plant		Anthriscus cerefolium	FooDB	Manually Annotated
Plant	Leaves	Lactuca sativa	FooDB	16666434
Plant		Nuphar lutea	FooDB	Manually Annotated
Plant		Lactuca sativa l. var. longifolia	FooDB	Manually Annotated
Plant	Fruit	Prunus armeniaca	FooDB	Phenol Explorer
Plant		Pachyrhizus erosus	FooDB	Manually Annotated
Plant	Fruit	Fragaria x ananassa	FooDB	Phenol Explorer
Plant		Lupinus albus	FooDB	Manually Annotated
Plant	Fruit	Ribes rubrum	FooDB	Phenol Explorer
Plant	Fruit	Fragaria x ananassa	FooDB	Phenol Explorer
Plant	Fruit	Rubus chamaemorus	FooDB	Phenol Explorer
Plant		Citrus paradisi x citrus maxima	FooDB	Manually Annotated
Plant		Elaeis	FooDB	Manually Annotated
Plant		Feijoa sellowiana	FooDB	Manually Annotated
Plant		Dysphania ambrosioides	FooDB	Manually Annotated
Plant		Cinnamomum	FooDB	Manually Annotated
Plant	Peel	Pyrus communis	FooDB	A. Escarpa and M. C. Gonzalez. Evaluation of High-Performance Liquid Chromatography for Determination of Phenolic Compounds in Pear Horticultural Cultivars. Chromatographia Vol. 51, No. 1/2, January 2000, 37-43
Plant		Ribes uva-crispa	FooDB	Manually Annotated
Plant		Raphanus sativus var. niger	FooDB	Manually Annotated
Plant	Flour	Glycine max	FooDB	Phenol Explorer
Plant	Leaves	Vaccinium myrtillus	FooDB	DUKE
Plant		Vaccinium	FooDB	Manually Annotated
Plant		Lablab purpureus	FooDB	Manually Annotated
Plant		Crocus sativus	FooDB	Manually Annotated
Plant	Fruit	Olea europaea	FooDB	DUKE
Plant	Fruit	Vaccinium virgatum	FooDB	Sellappan S, Akoh CC, Krewer G. Phenolic Compounds and Antioxidant Capacity of Georgia-Grown Blueberries and Blackberries. 2002. J. Agric. Food Chem. 2002, 50, 2432-2438
Plant		Syzygium jambos	FooDB	Manually Annotated
Plant		Salix pulchra	FooDB	Manually Annotated
Plant		Citrus maxima	FooDB	Manually Annotated
Plant		Fagus	FooDB	Manually Annotated
Plant	Peel	Pyrus communis	FooDB	18778075
Plant		Cydonia oblonga	FooDB	Manually Annotated
Plant		Cichorium intybus var. foliosum	FooDB	Phenol Explorer
Plant	Fruit	Gaylussacia baccata	FooDB	Phenol Explorer
Plant		Malus pumila	FooDB	PhytoHub
Plant	Flower	Tilia	FooDB	DUKE
Plant		Opuntia cochenillifera	FooDB	Manually Annotated
Plant	Oil	Glycine max	FooDB	Phenol Explorer
Plant		Cichorium intybus var. foliosum	FooDB	Phenol Explorer
Plant	Leaves	Spinacia oleracea	FooDB	DUKE
Plant		Cocos nucifera	FooDB	Manually Annotated
Plant		Thymus pulegioides	FooDB	Manually Annotated
Plant		Phaseolus coccineus	FooDB	Manually Annotated
Plant	Fruit	Vaccinium myrtillus	FooDB	Phenol Explorer
Plant	Fruit	Cucurbita	FooDB	Phenol Explorer
Plant	Leaves	Cichorium endivia	FooDB	DUKE
Plant		Mespilus germanica	FooDB	Manually Annotated
Plant		Tamarindus indica	FooDB	Manually Annotated
Plant		Brassica rapa var. perviridis	FooDB	Manually Annotated
Plant	Root	Daucus carota ssp. sativus	FooDB	DUKE
Plant	Shoot	Mentha x piperita	FooDB	DUKE
Plant	Fruit	Fragaria x ananassa	FooDB	S.Hakkinen, M. Heinonen, S. Karenlampi, H. Mykkanen, J. Ruuskanen, R. Torronen. Screening of selected flavonoids and phenolic acids in 19 berries. Food Research International 32 (1999) 345-353. https://www.sciencedirect.com/science/article/pii/S0963996999000952
Plant	Bean	Phaseolus vulgaris	FooDB	Phenol Explorer
Plant		Cucurbita pepo var. cylindrica	FooDB	Manually Annotated
Plant		Mentha aquatica	FooDB	Manually Annotated
Plant		Salvia elegans	FooDB	Manually Annotated
Plant		Mentha	FooDB	Manually Annotated
Plant	Fruit	Capsicum annuum var. annuum	FooDB	DUKE
Plant		Sagittaria latifolia	FooDB	Manually Annotated
Plant	Plant	Vicia faba	FooDB	DUKE
Plant	Leaves	Origanum vulgare	FooDB	DUKE
Plant	Fruit	Solanum melongena	FooDB	F. W. Knapp. Some Characteristics of Eggplant and Avocado Poiyphenolases. J. Food Science. 30(6), 930-936, 1965
Plant		Chenopodium quinoa	FooDB	Manually Annotated
Plant	Plant	Eriobotrya japonica	FooDB	DUKE
Plant		Sambucus	FooDB	Manually Annotated
Plant		Piper nigrum	FooDB	Phenol Explorer
Plant		Glycine max	FooDB	Manually Annotated
Plant		Syzygium cumini	FooDB	Manually Annotated
Plant		Pinus	FooDB	Manually Annotated
Plant		Psidium guajava	FooDB	Manually Annotated
Plant	Top part	Brassica rapa var. rapa	FooDB	Phenol Explorer
Plant	Plant	Allium ampeloprasum	FooDB	DUKE
Plant	Leaves	Brassica oleracea var. gemmifera	FooDB	DUKE
Plant	Seed	Carum carvi	FooDB	DUKE
Plant		Typha angustifolia	FooDB	Manually Annotated
Plant		Empetrum nigrum	FooDB	Manually Annotated
Plant		Myrica rubra	FooDB	Manually Annotated
Plant	Bean	Phaseolus vulgaris	FooDB	Phenol Explorer
Plant		Capsicum annuum	FooDB	Manually Annotated
Plant	Plant	Myristica fragrans	FooDB	DUKE
Plant		Valerianella locusta	FooDB	Manually Annotated
Plant		Capsicum annuum	FooDB	Manually Annotated
Plant	Peel	Pyrus communis	FooDB	A. Escarpa and M. C. Gonzalez. Evaluation of High-Performance Liquid Chromatography for Determination of Phenolic Compounds in Pear Horticultural Cultivars. Chromatographia Vol. 51, No. 1/2, January 2000, 37-43
Plant		Sisymbrium	FooDB	Manually Annotated
Plant	Fruit	Vaccinium deliciosum	FooDB	Phenol Explorer
Plant		Vanilla	FooDB	Manually Annotated
Plant		Piper nigrum	FooDB	Phenol Explorer
Plant	Fruit	Solanum lycopersicum var. lycopersicum	FooDB	Phenol Explorer
Plant	Peel	Malus pumila	FooDB	9818410
Plant	Fruit	Solanum lycopersicum var. lycopersicum	FooDB	Phenol Explorer
Plant		Carya	FooDB	Manually Annotated
Plant		Physalis philadelphica var. immaculata	FooDB	Manually Annotated
Plant	Fruit	Olea europaea	FooDB	Phenol Explorer
Plant		Borago officinalis	FooDB	Manually Annotated
Plant		Manihot esculenta	FooDB	Manually Annotated
Plant	Fruit	Olea europaea	FooDB	Phenol Explorer
Plant	Plant	Lactuca sativa	FooDB	DUKE
Plant	Juice	Pyrus communis	FooDB	Dilek Tanrioven and Aziz Eksi. Phenolic compounds in pear juice from different cultivars. Food Chemistry. 2005, 93(1), 89-93
Plant		Scorzonera hispanica	FooDB	Manually Annotated
Plant		Vigna radiata	FooDB	Manually Annotated
Plant		Vigna unguiculata ssp. sesquipedalis	FooDB	Manually Annotated
Plant	Bulb	Allium cepa	FooDB	DUKE
Plant		Angelica keiskei	FooDB	Manually Annotated
Plant	Plant	Prunus dulcis	FooDB	DUKE
Plant		Piper nigrum	FooDB	Phenol Explorer
Plant		Ocimum basilicum	FooDB	Phenol Explorer
Plant		Ipomoea aquatica	FooDB	Manually Annotated
Plant		Ocimum basilicum	FooDB	Phenol Explorer
Plant		Musa x paradisiaca	FooDB	Manually Annotated
Plant	Leaves	Brassica oleracea l. var. capitata l. f. alba dc.	FooDB	DUKE
Plant	Bean	Phaseolus vulgaris	FooDB	Phenol Explorer
Plant		Rubus spectabilis	FooDB	Manually Annotated
Plant	Leaves	Brassica oleracea var. capitata	FooDB	DUKE
Plant	Fruit	Prunus avium	FooDB	L. Gao, and G. Mazza. Characterization, Quantitation, and Distribution of Anthocyanins and Colorless Phenolics in Sweet Cherries. J. Agric. Food Chem., 1995, 43 (2), pp 343-346
Plant	Plant	Origanum vulgare	FooDB	DUKE
Plant	Seed	Theobroma cacao	FooDB	DUKE
Plant		Cantharellus cibarius	FooDB	Manually Annotated
Plant	Rhizome	Zingiber officinale	FooDB	DUKE
Plant		Sinapis alba	FooDB	Manually Annotated
Plant	Fruit	Rubus occidentalis	FooDB	Phenol Explorer
Plant		Brassica ruvo	FooDB	Manually Annotated
Plant		Carum carvi	FooDB	Phenol Explorer
Plant		Morus nigra	FooDB	Manually Annotated
Plant	Fruit	Vaccinium oxycoccos	FooDB	Phenol Explorer
Plant		Apium graveolens var. secalinum	FooDB	Manually Annotated
Plant	Leaves	Oenothera biennis	FooDB	DUKE
Plant		Allium fistulosum	FooDB	Phenol Explorer
Plant		Abelmoschus esculentus	FooDB	Manually Annotated
Plant		Salvia officinalis	FooDB	Phenol Explorer
Plant		Anethum graveolens	FooDB	Manually Annotated
Plant		Pinus edulis	FooDB	Manually Annotated
Plant	Fruit	Cucumis sativus	FooDB	DUKE
Plant		Salvia officinalis	FooDB	Phenol Explorer
Plant		Anethum graveolens	FooDB	Manually Annotated
Plant		Brassica rapa var. rapa	FooDB	Manually Annotated
Plant		Passiflora edulis	FooDB	Manually Annotated
Plant		Opuntia macrorhiza	FooDB	Manually Annotated
Plant		Vigna angularis	FooDB	Manually Annotated
Plant	Fruit	Olea europaea	FooDB	Phenol Explorer
Plant		Brassica rapa var. rapa	FooDB	Manually Annotated
Plant		Prunus domestica	FooDB	PhytoHub
Plant	Fruit	Olea europaea	FooDB	Phenol Explorer
Plant		Manilkara zapota	FooDB	Manually Annotated
Plant		Myristica fragrans	FooDB	Phenol Explorer
Plant		Cucurbita pepo var. clypeata	FooDB	Manually Annotated
Plant		Cichorium intybus var. sativum	FooDB	Manually Annotated
Plant		Allium cepa	FooDB	Manually Annotated
Plant		Corylus	FooDB	Manually Annotated
Plant		Malus	FooDB	Manually Annotated
Plant	Stem	Petroselinum crispum	FooDB	DUKE
Plant		Vaccinium oxycoccos	FooDB	PhytoHub
Plant		Juglans	FooDB	Manually Annotated
Plant	Fruit	Pyrus communis	FooDB	DUKE
Plant		Salvia officinalis	FooDB	Phenol Explorer
Plant		Mangifera indica	FooDB	Manually Annotated
Plant	Fruit	Vaccinium ovalifolium	FooDB	Phenol Explorer
Plant	Fruit	Prunus persica var. persica	FooDB	Phenol Explorer
Plant	Leaves	Verbena officinalis	FooDB	DUKE
Plant			FooDB	Manually Annotated
Plant	Fruit	Vaccinium parvifolium	FooDB	Phenol Explorer
Plant		Auricularia auricula-judae	FooDB	Manually Annotated
Plant	Plant		FooDB	DUKE
Plant		Attalea speciosa	FooDB	Manually Annotated
Plant		Syzygium aromaticum	FooDB	Phenol Explorer
Plant		Juglans ailanthifolia	FooDB	Manually Annotated
Plant	Skin	Pyrus x bretschneideri	FooDB	18778075
Plant	Fruit	Prunus persica var. persica	FooDB	Phenol Explorer
Plant	Plant		FooDB	DUKE
Plant	Fruit	Coffea arabica	FooDB	DUKE
Plant		Polygonum alpinum	FooDB	Manually Annotated
Plant		Phaseolus vulgaris	FooDB	Manually Annotated
Plant		Brassica juncea	FooDB	Manually Annotated
Plant		Phaseolus vulgaris	FooDB	Manually Annotated
Plant		Pediomelum esculentum	FooDB	Manually Annotated
Plant		Origanum vulgare	FooDB	Phenol Explorer
Plant	Peel	Malus pumila	FooDB	9818410
Plant		Auricularia polytricha	FooDB	Manually Annotated
Plant	Pollen or spore	Helianthus annuus	FooDB	DUKE
Plant		Camellia oleifera	FooDB	Manually Annotated
Plant	Plant	Cucumis melo	FooDB	DUKE
Plant	Fruit	Pyrus communis	FooDB	Phenol Explorer
Plant	Leaf	Coffea arabica	FooDB	DUKE
Plant	Fruit	Malus pumila	FooDB	DUKE
Plant	Fruit	Photinia melanocarpa	FooDB	Phenol Explorer
Plant		Chrysanthemum coronarium	FooDB	Manually Annotated
Plant		Eleocharis dulcis	FooDB	Manually Annotated
Plant	Juice	Vitis vinifera	FooDB	Phenol Explorer
Plant		Brassica oleracea var. italica	FooDB	Manually Annotated
Plant	Shoot	Satureja montana	FooDB	DUKE
Plant		Actinidia chinensis	FooDB	Manually Annotated
Plant		Brassica oleracea var. italica	FooDB	Manually Annotated
Plant	Juice	Pyrus communis	FooDB	Phenol Explorer
Plant	Fruit	Vaccinium uliginosum	FooDB	Phenol Explorer
Plant		Solanum tuberosum	FooDB	Phenol Explorer
Plant	Seed	Foeniculum vulgare	FooDB	DUKE
Plant		Rubus arcticus	FooDB	Manually Annotated
Plant		Pimenta dioica	FooDB	Manually Annotated
Plant		Medicago sativa	FooDB	Manually Annotated
Plant	Inflorescence	Salvia officinalis	FooDB	DUKE
Plant		Agaricus bisporus	FooDB	Manually Annotated
Plant		Cajanus cajan	FooDB	Manually Annotated
Plant		Vigna mungo	FooDB	Manually Annotated
Plant		Rumex articus	FooDB	Manually Annotated
Plant	Fruit	Prunus avium	FooDB	Phenol Explorer
Plant		Hibiscus sabdariffa	FooDB	Manually Annotated
Plant		Benincasa hispida	FooDB	Manually Annotated
Plant		Canarium ovatum	FooDB	Manually Annotated
Plant		Solanum melongena	FooDB	Manually Annotated
Plant		Ribes aureum var. villosum	FooDB	Manually Annotated
Plant		Solanum melongena	FooDB	Manually Annotated
Plant	Leaves	Prunus persica	FooDB	DUKE
Plant	Leaves	Beta vulgaris ssp. cicla	FooDB	Phenol Explorer
Plant	Fruit	Rubus idaeus	FooDB	DUKE
Plant	Fruit	Vaccinium vitis-idaea	FooDB	Phenol Explorer
Plant	Root	Daucus carota	FooDB	DUKE
Plant		Brassica oleracea var. gongylodes	FooDB	Manually Annotated
Plant		Juglans cinerea	FooDB	Manually Annotated
Plant		Eruca vesicaria ssp. sativa	FooDB	Manually Annotated
Plant		Artocarpus altilis	FooDB	Manually Annotated
Plant	Leaves	Castanea sativa	FooDB	DUKE
Plant	Flower	Solanum tuberosum	FooDB	DUKE
Plant		Metroxylon sagu	FooDB	Manually Annotated
Plant		Vigna unguiculata	FooDB	Manually Annotated
Plant	Leaves	Thymus vulgaris	FooDB	DUKE
Plant		Cynara scolymus	FooDB	Manually Annotated
Plant		Cyathea	FooDB	Manually Annotated
Plant		Vitis rotundifolia	FooDB	Manually Annotated
Plant		Brosimum alicastrum	FooDB	Manually Annotated
Plant		Lentinus edodes	FooDB	Manually Annotated
Plant		Psidium cattleianum	FooDB	Manually Annotated
Plant		Daucus carota ssp. sativus	FooDB	PhytoHub
Plant	Leaves	Beta vulgaris ssp. cicla	FooDB	Phenol Explorer
Plant		Castanea mollissima	FooDB	Manually Annotated
Plant		Morus	FooDB	Manually Annotated
Plant		Lepidium sativum	FooDB	Manually Annotated
Plant		Vitis labrusca	FooDB	Manually Annotated
Plant		Phytolacca americana	FooDB	Manually Annotated
Plant		Grifola frondosa	FooDB	Manually Annotated
Plant	Leaves	Beta vulgaris var. rubra	FooDB	DUKE
Plant		Prunus avium	FooDB	PhytoHub
Plant		Helianthus tuberosus	FooDB	Manually Annotated
Plant	Plant	Annona muricata	FooDB	DUKE
Plant	Fruit	Vaccinium ovatum	FooDB	Phenol Explorer
Plant		Tetragonia tetragonioides	FooDB	Manually Annotated
Plant		Artemisia vulgaris	FooDB	Manually Annotated
Plant	Seed	Helianthus annuus	FooDB	DUKE
Plant		Cucumis metuliferus	FooDB	Manually Annotated
Plant		Myrica	FooDB	Manually Annotated
Plant	Stem	Beta vulgaris ssp. cicla	FooDB	Phenol Explorer
Plant		Nephelium lappaceum	FooDB	Manually Annotated
Plant	Leaves	Anethum graveolens	FooDB	DUKE
Plant	Fruit	Capsicum annuum	FooDB	DUKE
Plant		Petroselinum crispum	FooDB	Phenol Explorer
Plant		Castanea crenata	FooDB	Manually Annotated
Plant		Solanum lycopersicum	FooDB	Manually Annotated
Plant	Oil	Olea europaea	FooDB	Phenol Explorer
Plant	Plant		FooDB	DUKE
Plant		Litchi chinensis	FooDB	Manually Annotated
Plant		Solanum lycopersicum	FooDB	Manually Annotated
Plant		Corylus avellana	FooDB	Manually Annotated
Plant		Solanum melongena	FooDB	Manually Annotated
Plant		Quercus	FooDB	Manually Annotated
Plant	Root	Raphanus sativus	FooDB	DUKE
Plant		Brassica oleracea var. italica	FooDB	PhytoHub
Plant	Fruit	Citrus x paradisi	FooDB	Phenol Explorer
Plant		Peanut	HMDB	34986597
Plant	Fruit	Citrus x paradisi	FooDB	Phenol Explorer
Plant		Malpighia emarginata	FooDB	Manually Annotated
Plant	Bean	Soy	HMDB	34986597
Plant		Physalis	FooDB	Manually Annotated
Plant		Common pea	HMDB	34986597
Plant	Plant	Ficus carica	FooDB	DUKE
Plant		Thelesperma	FooDB	Manually Annotated
Plant		Solanum melongena	FooDB	PhytoHub
Plant	Bean	Coffea arabica	HMDB	34986597
Plant		Brassica oleracea var. sabauda	FooDB	Manually Annotated
Plant	Stem	Beta vulgaris ssp. cicla	FooDB	Phenol Explorer
Plant	Plant	Hyssopus officinalis	FooDB	DUKE
Plant		Dandelion	HMDB	34986597
Plant	Fruit	Citrus limon	FooDB	DUKE
Plant		Brassica napus	FooDB	Manually Annotated
Plant		Asparagus officinalis	FooDB	Manually Annotated
Plant		Chamerion angustifolium	FooDB	Manually Annotated

Source Type	Activity	Data Source	Reference
Drugs	Antimicrobial	U.S. Environmental Protection Agency	CompTox
Cosmetics	Not Available	U.S. Environmental Protection Agency	CompTox
Domestics	Not Available	U.S. Environmental Protection Agency	CompTox

Host Biospecimen and Location

Host and Biospecimen	Status	Mean	Std	Min	Max	Units	Age	Sex	Health Condition	Data Source	Reference
Human Feces	Detected but not Quantified									HMDB
Human Blood	Detected and Quantified	0.033				uM	Adult (>18 years old)	Both	Normal	HMDB	11308321
Human Urine	Detected and Quantified	0.16				umol/mmol creatinine	Adult (>18 years old)	Both	Normal	HMDB	17426744
Human Urine	Detected and Quantified	0.317				umol/mmol creatinine	Adult (>18 years old)	Both	Normal	HMDB	27273479
Human Urine	Detected and Quantified	0.41				umol/mmol creatinine	Adult (>18 years old)	Both	Normal	HMDB	17426744
Human Blood	Detected and Quantified			0	18.887	uM	Adult (>18 years old)	Both	Normal	HMDB	19812218
Human Urine	Detected and Quantified	0.0065	0.013			umol/mmol creatinine	Adult (>18 years old)	Both	Normal	HMDB	16197573
Human Urine	Detected and Quantified	0.013	0.0065			umol/mmol creatinine	Adult (>18 years old)	Both	Normal	HMDB	16197573
Human Urine	Detected and Quantified	0.019	0.032			umol/mmol creatinine	Adult (>18 years old)	Both	Normal	HMDB	16197573
Human Urine	Detected and Quantified	0.026	0.013			umol/mmol creatinine	Adult (>18 years old)	Both	Normal	HMDB	16197573
Human Urine	Detected and Quantified	0.026	0.026			umol/mmol creatinine	Adult (>18 years old)	Both	Normal	HMDB	16197573
Human Urine	Detected and Quantified	0.046	0.019			umol/mmol creatinine	Adult (>18 years old)	Both	Normal	HMDB	16197573
Human Urine	Detected and Quantified			0.0460	1.410	umol/mmol creatinine	Adult (>18 years old)	Both	Normal	HMDB	26814424
Human Urine	Detected and Quantified	0.13	0.032			umol/mmol creatinine	Adult (>18 years old)	Both	Normal	HMDB	16197573
Human Blood	Detected and Quantified	0.241	0.041			uM	Adult (>18 years old)	Male	Normal	HMDB	19812218
Human Blood	Detected and Quantified	0.366	0.088			uM	Adult (>18 years old)	Male	Normal	HMDB	19812218
Human Urine	Detected and Quantified	0.382	0.065			umol/mmol creatinine	Adult (>18 years old)	Male	Normal	HMDB	19812218
Human Blood	Detected and Quantified	0.428	0.147			uM	Adult (>18 years old)	Male	Normal	HMDB	19812218
Human Urine	Detected and Quantified	0.620	0.240			umol/mmol creatinine	Adult (>18 years old)	Both	Normal	HMDB	16870009
Human Blood	Detected and Quantified	0.702	0.223			uM	Adult (>18 years old)	Male	Normal	HMDB	19812218
Human Urine	Detected and Quantified	0.760	0.567			umol/mmol creatinine	Adult (>18 years old)	Both	Normal	HMDB	16870009
Human Blood	Detected and Quantified	1.943	1.055			uM	Adult (>18 years old)	Male	Normal	HMDB	19812218
Human Feces	Detected and Quantified	11.268	1.388			nmol/g wet feces	Adult (>18 years old)	Both	Normal	HMDB	24010549
Human Feces	Detected and Quantified	11.490	3.663			nmol/g wet feces	Adult (>18 years old)	Both	Normal	HMDB	24010549
Human Feces	Detected and Quantified	11.545	1.665			nmol/g wet feces	Adult (>18 years old)	Both	Normal	HMDB	24010549
Human Feces	Detected and Quantified	11.823	1.776			nmol/g wet feces	Adult (>18 years old)	Both	Normal	HMDB	24010549
Human Feces	Detected and Quantified	14.987	13.322			nmol/g wet feces	Not Specified	Not Specified	Normal	HMDB	20669995
Human Urine	Detected and Quantified	2.1		0.1	6.1	umol/mmol creatinine	Children (1-13 years old)	Both	Normal	HMDB	8087979
Human Blood	Detected and Quantified	2.12	1.547			uM	Adult (>18 years old)	Male	Normal	HMDB	19812218
Human Blood	Detected and Quantified	2.434	2.174			uM	Adult (>18 years old)	Male	Normal	HMDB	19812218
Human Urine	Detected and Quantified	2.6		1.2	4.1	umol/mmol creatinine	Adolescent (13-18 years old)	Both	Normal	HMDB	8087979
Human Urine	Detected and Quantified	3.5		1.2	22.9	umol/mmol creatinine	Children (1-13 years old)	Both	Normal	HMDB	8087979
Human Blood	Detected and Quantified	3.915	1.695			uM	Adult (>18 years old)	Male	Normal	HMDB	19812218
Human Epidermis	Detected but not Quantified						Not Specified	Not Specified	Normal	HMDB	34986597
Human Platelet	Detected but not Quantified						Not Specified	Not Specified	Normal	HMDB	34986597
Human Prostate	Detected but not Quantified						Not Specified	Not Specified	Normal	HMDB	34986597
Human Feces	Detected but not Quantified						Not Specified	Not Specified	Normal	HMDB	20669995
Human Feces	Detected but not Quantified						Adult (>18 years old)	Male	Normal	HMDB	20809621
Human Feces	Detected but not Quantified						Adult (>18 years old)	Male	Normal	HMDB	20809621
Human Feces	Detected but not Quantified						Adult (>18 years old)	Both	Normal	HMDB	24029555
Human Feces	Detected but not Quantified						Adult (>18 years old)	Both	Normal	HMDB	27543620
Human Feces	Detected but not Quantified						Adult (>18 years old)	Both	Normal	HMDB	25037050
Human Feces	Detected but not Quantified						Adult (>18 years old)	Both	Normal	HMDB	29808030
Human Urine	Detected but not Quantified						Adult (>18 years old)	Both	Normal	HMDB	32966057
Human Blood	Detected but not Quantified						Adult (>18 years old)	Both	Normal	HMDB	32966057

External Links

HMDB ID

HMDB0001964

DrugBank ID

DB01880

Phenol Explorer Compound ID

Not Available

FooDB ID

KNApSAcK ID

Chemspider ID

KEGG Compound ID

BioCyc ID

BiGG ID

Not Available

Wikipedia Link

Caffeic_acid

METLIN ID

Not Available

PubChem Compound

689043

PDB ID

Not Available

ChEBI ID

16433

Food Biomarker Ontology

Not Available

References

Synthesis Reference

Not Available

General References

Guneral F, Bachmann C: Age-related reference values for urinary organic acids in a healthy Turkish pediatric population. Clin Chem. 1994 Jun;40(6):862-6. [PubMed:8087979 ]
Nakazawa T, Ohsawa K: Metabolites of orally administered Perilla frutescens extract in rats and humans. Biol Pharm Bull. 2000 Jan;23(1):122-7. doi: 10.1248/bpb.23.122. [PubMed:10706426 ]
Saija A, Tomaino A, Trombetta D, De Pasquale A, Uccella N, Barbuzzi T, Paolino D, Bonina F: In vitro and in vivo evaluation of caffeic and ferulic acids as topical photoprotective agents. Int J Pharm. 2000 Apr 10;199(1):39-47. doi: 10.1016/s0378-5173(00)00358-6. [PubMed:10794925 ]
Olthof MR, Hollman PC, Katan MB: Chlorogenic acid and caffeic acid are absorbed in humans. J Nutr. 2001 Jan;131(1):66-71. doi: 10.1093/jn/131.1.66. [PubMed:11208940 ]
Uno J, Tanaka R, Branchini ML, Aoki FH, Yarita K, Sano A, Fukushima K, Mikami Y, Nishimura K, Miyaji M: Atypical Cryptococcus neoformans isolate from an HIV-infected patient in Brazil. Nihon Ishinkin Gakkai Zasshi. 2001;42(3):127-32. doi: 10.3314/jjmm.42.127. [PubMed:11479533 ]
Quiles JL, Farquharson AJ, Simpson DK, Grant I, Wahle KW: Olive oil phenolics: effects on DNA oxidation and redox enzyme mRNA in prostate cells. Br J Nutr. 2002 Sep;88(3):225-34; discussion 223-4. doi: 10.1079/BJN2002620. [PubMed:12207832 ]
Gonthier MP, Verny MA, Besson C, Remesy C, Scalbert A: Chlorogenic acid bioavailability largely depends on its metabolism by the gut microflora in rats. J Nutr. 2003 Jun;133(6):1853-9. doi: 10.1093/jn/133.6.1853. [PubMed:12771329 ]
Li X, Yu C, Cai Y, Liu G, Jia J, Wang Y: Simultaneous determination of six phenolic constituents of danshen in human serum using liquid chromatography/tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Jun 5;820(1):41-7. doi: 10.1016/j.jchromb.2005.03.005. Epub 2005 Apr 19. [PubMed:15866491 ]
Verma RP: A classical QSAR study on some platelet aggregation inhibitors. Mini Rev Med Chem. 2006 Apr;6(4):467-82. doi: 10.2174/138955706776361484. [PubMed:16613584 ]
Lafay S, Gil-Izquierdo A, Manach C, Morand C, Besson C, Scalbert A: Chlorogenic acid is absorbed in its intact form in the stomach of rats. J Nutr. 2006 May;136(5):1192-7. doi: 10.1093/jn/136.5.1192. [PubMed:16614403 ]
Mennen LI, Sapinho D, Ito H, Bertrais S, Galan P, Hercberg S, Scalbert A: Urinary flavonoids and phenolic acids as biomarkers of intake for polyphenol-rich foods. Br J Nutr. 2006 Jul;96(1):191-8. doi: 10.1079/bjn20061808. [PubMed:16870009 ]
Kawaguchi H, Katsuyama Y, Danyao D, Kahar P, Nakamura-Tsuruta S, Teramura H, Wakai K, Yoshihara K, Minami H, Ogino C, Ohnishi Y, Kondo A: Caffeic acid production by simultaneous saccharification and fermentation of kraft pulp using recombinant Escherichia coli. Appl Microbiol Biotechnol. 2017 Jul;101(13):5279-5290. doi: 10.1007/s00253-017-8270-0. Epub 2017 Apr 10. [PubMed:28396925 ]

Showing metabocard for Caffeic acid (MMDBc0000577)

MOL for #<Metabolite:0x0000556b67600158>

3D MOL for #<Metabolite:0x0000556b67600158>

3D SDF for #<Metabolite:0x0000556b67600158>

3D-SDF for #<Metabolite:0x0000556b67600158>

PDB for #<Metabolite:0x0000556b67600158>

3D PDB for #<Metabolite:0x0000556b67600158>

SMILES for #<Metabolite:0x0000556b67600158>

INCHI for #<Metabolite:0x0000556b67600158>

Structure for #<Metabolite:0x0000556b67600158>

3D Structure for #<Metabolite:0x0000556b67600158>