MiMeDB: Klebsiella pneumoniae (MMDBm0001066)

Microbe Identification

Microbe name

Klebsiella pneumoniae

NCBI Taxonomy ID

573

Microbe Taxonomy

Superkingdom

Bacteria

Kingdom

Eubacteria

Phylum

Proteobacteria

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Species

pneumoniae

Strain

Not Available

Microbe Properties

Gram staining properties

Positive

Shape

Not Available

Mobility

Not Available

Flagellar presence

Not Available

Number of membranes

Not Available

Oxygen preference

Facultative anaerobe

Optimal temperature

Not Available

Temperature range

Not Available

Habitat

Not Available

Biotic relationship

Not Available

Cell arrangement

Not Available

Sporulation

Not Available

Metabolism

Not Available

Energy source

Not Available

Host and Biospecimens

Host	Body site	Biospecimen	Data Source	Reference
Human			Human Oral Microbiome Database (HOMD)	20624719
Human	Nasal cavity		BacDive	34718743
Human	Lung		BacDive	34718743
Human	Nasopharynx		BacDive	34718743
Human	Large intestine		BacDive	34718743
Human	Nasal cavity		BacDive	34718743
Human	Rectum		BacDive	34718743
Human	Nasopharynx		BacDive	34718743
Human	Lower respiratory tract		BacDive	34718743
Human	Trachea		BacDive	34718743
Human	Lower respiratory tract		BacDive	34718743
Human	Lung	Sputum	Disbiome	25403149
Human	Gingiva	Subgingival plaque	Disbiome	27717873
Human	Skin		Disbiome	31883828
Human	Large intestine	Feces	Disbiome	29041989
Human	Large intestine	Feces	Disbiome	30701194
Human	Large intestine	Feces	Disbiome	31530647
Human	Large intestine	Feces	Disbiome	24178246
Human	Large intestine	Feces	Disbiome	31921729
Human	Large intestine	Feces	Disbiome	31921729
Human	Gingiva	Subgingival plaque	Disbiome	27717873

Health Effects

Host	Related Health Condition	Microbal response/effect	Data Source	Reference
Human	Chronic rhinitis		BacDive
Human	Pneumonia		BacDive
Human	Sinusitis		BacDive
Human	Cystic fibrosis		BacDive
Human	Chronic obstructive pulmonary disease	Elevated	Disbiome	25403149
Human	Systemic Lupus Erythematosus	Reduced	Disbiome	31883828
Human	Alcoholism	Elevated	Disbiome	29041989
Human	Colorectal cancer	Elevated	Disbiome	31530647
Human	Cystic fibrosis	Elevated	Disbiome	24178246
Human	Obesity	Elevated	Disbiome	31921729
Human	Non-alcoholic fatty liver disease	Elevated	Disbiome	31921729

Related Metabolites

Metabolic Reactions

Reactions

Reaction ID	Precursor	Product	Enzyme	Reaction Type	Data Source	Reference
MMDBr0012852	6-Phosphogluconic acid	Carbon dioxide	6-phosphogluconate dehydrogenase, decarboxylating	Dehydrogenation	RHEA	34755880
MMDBr0012884	D-Glyceraldehyde 3-phosphate	(2R)-3-phospho-glyceroyl phosphate	Glyceraldehyde-3-phosphate dehydrogenase	Dehydrogenation	RHEA	34755880
MMDBr0012927	3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic acid	Hydrogen Ion	Pyrroloquinoline-quinone synthase	Synthesis	RHEA	34755880
MMDBr0012934	Hydrogen Ion	Carbon dioxide	Carbonic anhydrase	Carbonate dehydration (or hydration of CO2)	RHEA	34755880
MMDBr0012936	Citric acid	Acetic acid	Citrate lyase alpha chain	Non-hydrolytic bond cleavage (or its reversal)	RHEA	34755880
MMDBr0012960	Adenosine triphosphate	ADP	Probable D-xylulose kinase A	Phosphorylation	RHEA	34755880
MMDBr0012981	alpha-D-mannose 1-phosphate	D-mannose 6-phosphate	Phosphomannomutase/phosphoglucomutase	Transfers of a phosphate group; Isomerization; Intramolecular transfer of functional group	RHEA	34755880
MMDBr0013164	alpha-Ketoglutarate	(2R)-Homocitric acid	Homocitrate synthase AksA	Synthesis	RHEA	34755880
MMDBr0013179	Adenosine triphosphate	ADP	Replicase large subunit	Synthesis of a primer	RHEA	34755880
MMDBr0013236	Water	5-Methylthioribose	Aminodeoxyfutalosine nucleosidase	Hydrolysis of a nucleotide	RHEA	34755880
MMDBr0013278	Adenosine triphosphate	ADP	Trifunctional NAD biosynthesis/regulator protein NadR	Phosphorylation	RHEA	34755880
MMDBr0013362	L-Arabinose	L-Ribulose	L-arabinose isomerase	Isomerization	RHEA	34755880
MMDBr0013390	3'-dephospho-CoA	2'-(5''-triphospho-alpha-D-ribosyl)-3'-dephospho-CoA	Probable 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase	Synthesis	RHEA	34755880
MMDBr0013404	alpha-D-mannose 1-phosphate	diphosphate	Alginate biosynthesis protein AlgA	Synthesis	RHEA	34755880
MMDBr0013500	Adenosine triphosphate	ADP	Hexokinase	Phosphorylation	RHEA	34755880
MMDBr0013530	Acetyl-CoA	CoA	Aminoglycoside N(6')-acetyltransferase type 1	N-Acetylation	RHEA	34755880
MMDBr0013650	3-maleylpyruvic acid	3-Fumarylpyruvate	Maleylpyruvate isomerase	Isomerization	RHEA	34755880
MMDBr0013659	Guanosine triphosphate	7,8-dihydroneopterin 3'-triphosphate	Bifunctional protein FolKE	Hydrolysis	RHEA	34755880
MMDBr0013664	ADP-D-glycero-beta-D-manno-heptose	ADP-L-glycero-beta-D-manno-heptose	ADP-L-glycero-D-manno-heptose-6-epimerase	Epimerization	RHEA	34755880
MMDBr0013686	Water	Adenine	Aminodeoxyfutalosine nucleosidase	Hydrolysis of a nucleotide	RHEA	34755880
MMDBr0013701	D-Arabitol	D-Xylulose	D-arabinitol 4-dehydrogenase	Dehydrogenation	RHEA	34755880
MMDBr0013760	Adenosine triphosphate	ADP	Streptomycin 3''-kinase	Phosphorylation	RHEA	34755880
MMDBr0013773	1-(5-phosphoribosyl)-ATP	Phosphoribosyl pyrophosphate	ATP phosphoribosyltransferase	Transfer of a ribosyl group	RHEA	34755880
MMDBr0013784	D-Glyceraldehyde 3-phosphate	Dihydroxyacetone phosphate	Bifunctional PGK/TIM	Isomerization	RHEA	34755880
MMDBr0013866	Acetyl-CoA	(3S)-Citryl-CoA	Citrate lyase alpha chain	Non-hydrolytic bond cleavage (or its reversal)	RHEA	34755880
MMDBr0013896	Polyphosphate	Polyphosphate	ADP-polyphosphate phosphotransferase	Transfer of phosphate group	RHEA	34755880
MMDBr0013906	Mannitol 1-phosphate	beta-D-Fructose 6-phosphate	Mannitol-1-phosphate 5-dehydrogenase	Dehydrogenation	RHEA	34755880
MMDBr0013921	(R)-4'-phosphopantetheine	3'-dephospho-CoA	Phosphopantetheine adenylyltransferase	Dephosphorylation	RHEA	34755880
MMDBr0013926	D-Sorbitol 6-phosphate	beta-D-Fructose 6-phosphate	Sorbitol-6-phosphate 2-dehydrogenase	Dehydrogenation	RHEA	34755880
MMDBr0013930	Glucose 1-phosphate	diphosphate	UTP--glucose-1-phosphate uridylyltransferase AglF	N-Acetylation	RHEA	34755880
MMDBr0013952	1-(5-phosphoribosyl)-5'-AMP	1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide	Histidine biosynthesis bifunctional protein HisIE	Hydrolysis; Synthesis	RHEA	34755880
MMDBr0013969	Adenosine triphosphate	3''-O-adenylylstreptomycin	Aminoglycoside (3'') (9) adenylyltransferase	Reversible transfer of an adenylyl group	RHEA	34755880
MMDBr0013988	Maltose 6'-phosphate	D-Glucose	6-phospho-alpha-glucosidase	Carbohydrate hydrolysis	RHEA	34755880
MMDBr0013989	Maltose 6'-phosphate	D-Glucose	6-phospho-alpha-glucosidase	Carbohydrate hydrolysis	RHEA	34755880
MMDBr0014005	Hydrogen Ion	Carbon dioxide	Urease subunit alpha	Hydrolysis of urea	RHEA	34755880
MMDBr0014039	(3S)-Citryl-CoA	Acetyl-CoA	Citrate lyase subunit beta	Non-hydrolytic bond cleavage (or its reversal)	RHEA	34755880
MMDBr0014083	Shikimate 3-phosphate	5-O-(1-Carboxyvinyl)-3-phosphoshikimate	Pentafunctional AROM polypeptide	Synthesis; Dehydration and isomerisation; Oxidation; Phosphorylation; Transfer of a carboxyvinyl group	RHEA	34755880
MMDBr0014091	Adenosine triphosphate	diphosphate	Nicotinamide-nucleotide adenylyltransferase	Synthesis	RHEA	34755880
MMDBr0014105	(S)-malate(2-)	Hydrogen Ion	Malate dehydrogenase	Dehydrogenation	RHEA	34755880
MMDBr0014146	alpha-Ketoglutarate	L-Glutamic acid	Probable aspartate/prephenate aminotransferase	Amine group addition	RHEA	34755880
MMDBr0014158	Adenosine triphosphate	6-phospho-beta-D-glucosyl-(1->4)-D-glucose	Beta-glucoside kinase	Phosphorylation	RHEA	34755880
MMDBr0014178	Uridine diphosphate glucose	Uridine diphosphategalactose	UDP-glucose 4-epimerase	Epimerization	RHEA	34755880
MMDBr0014190	5-Methylthioribose	ADP	5-deoxyribose kinase	Phosphorylation	RHEA	34755880
MMDBr0014254	D-Xylose	D-Xylulose	Xylose isomerase	Isomerization	RHEA	34755880
MMDBr0014256	1-(5-phosphoribosyl)-ATP	1-(5-phosphoribosyl)-5'-AMP	Phosphoribosyl-ATP pyrophosphatase	Dephosphorylation; Synthesis	RHEA	34755880
MMDBr0014301	NAD	3-Hydroxypropanal	1,3-propanediol dehydrogenase	Dehydrogenation	RHEA	34755880
MMDBr0014416	Uridine diphosphategalactose	UDP-D-Galacto-1,4-furanose	UDP-galactopyranose mutase	Intramolecular transfer of functional group	RHEA	34755880
MMDBr0014432	Adenosine triphosphate	ADP	Aminoglycoside 3'-phosphotransferase	Transfer of phosphate group	RHEA	34755880
MMDBr0014444	Phosphate	Ribose-1-phosphate	Pyrimidine-nucleoside phosphorylase	Phosphorylation	RHEA	34755880
MMDBr0014530	Hydrogen Ion	(2S)-2-acetolactic acid	Acetolactate synthase	Synthesis	RHEA	34755880
MMDBr0014663	(S)-acetoin	Diacetyl	L-2,3-butanediol dehydrogenase	Dehydrogenation; Reduction	RHEA	34755880
MMDBr0014667	Hydrogen Ion	5-Hydroxyisourate	FAD-dependent urate hydroxylase	Hydroxylation	RHEA	34755880
MMDBr0014790	di-trans,octa-cis-undecaprenyl phosphate	alpha-D-glucosyl di-trans,octa-cis-undecaprenyl diphosphate	Undecaprenyl-phosphate glucose phosphotransferase	Transfer of phosphate group	RHEA	34755880
MMDBr0014864	Hydrogen Ion	Hydrogen Ion	Melibiose carrier protein	Transport of melibiose	RHEA	34755880
MMDBr0014865	Hydrogen Ion	Hydrogen Ion	Low-affinity putrescine importer PlaP	Transport	RHEA	34755880
MMDBr0014866	Hydrogen Ion	Hydrogen Ion	Low-affinity putrescine importer PlaP	Transport	RHEA	34755880
MMDBr0014941	5'-Deoxyadenosine	5'-Deoxyribose	Aminodeoxyfutalosine nucleosidase	Hydrolysis of a nucleotide	RHEA	34755880
MMDBr0014942	5'-Deoxyadenosine	5'-Deoxyribose	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase	Hydrolysis of a nucleotide	RHEA	34755880
MMDBr0014980	Water	Hydrogen Ion	Delta-1-pyrroline-5-carboxylate dehydrogenase	Dehydrogenation	RHEA	34755880
MMDBr0015402	(S)-2,3,4,5-tetrahydrodipicolinate	(2S,4S)-4-Hydroxy-2,3,4,5-tetrahydrodipicolinate	4-hydroxy-tetrahydrodipicolinate reductase	Reduction	RHEA	34755880
MMDBr0015405	(S)-2,3,4,5-tetrahydrodipicolinate	(2S,4S)-4-Hydroxy-2,3,4,5-tetrahydrodipicolinate	4-hydroxy-tetrahydrodipicolinate reductase	Reduction	RHEA	34755880
MMDBr0016002	CoA	Acetyl-CoA	Pyruvate-flavodoxin oxidoreductase	Redox reaction	RHEA	34755880
MMDBr0017976	4-methylsulfanyl-2-oxobutanoic acid	3-(4-hydroxyphenyl)pyruvic acid	Tyrosine aminotransferase	Amine group addition	RHEA	34755880
MMDBr0016398	Fe2+	Iron(3+)	DNA protection during starvation protein	Not Available	RHEA	34755880
MMDBr0016908	Hydrogen Ion	Carbon dioxide	Oxaloacetate decarboxylase alpha chain	Decarboxylation	RHEA	34755880
MMDBr0017348	Adenosine triphosphate	9-O-adenylylspectinomycin	Aminoglycoside (3'') (9) adenylyltransferase	Reversible transfer of an adenylyl group	RHEA	34755880
MMDBr0017868	alpha-Ketoglutarate	3-(4-hydroxyphenyl)pyruvic acid	L-tyrosine:2-oxoglutarate aminotransferase amt1	Amine group addition	RHEA	34755880
MMDBr0024355	Adenosine triphosphate	Hydrogen Ion	Tyrosine-protein kinase ptk	Phosphorylation	RHEA	34755880
MMDBr0024497	S-Adenosylmethionine	Hydrogen Ion	Type I restriction enzyme MjaVII methylase subunit	Methylation	RHEA	34755880
MMDBr0024569	alpha-Ketoglutarate	L-Glutamic acid	Aromatic-amino-acid aminotransferase 1	Amine group addition	RHEA	34755880
MMDBr0024572	L-Serine	Hydrogen Ion	Serine-type anaerobic sulfatase-maturating enzyme	Not Available	RHEA	34755880
MMDBr0024636	Phosphate	Ribose-1-phosphate	Probable 6-oxopurine nucleoside phosphorylase	Phosphorylation	RHEA	34755880
MMDBr0024686	Water	Hydrogen Ion	Nitrogenase iron protein	Nitrogen fixation	RHEA	34755880
MMDBr0024747	NADP(+)	Hydrogen Ion	Probable tRNA-dihydrouridine synthase	Synthesis	RHEA	34755880
MMDBr0024753	L-Proline	Hydrogen Ion	Proline dehydrogenase 1	Dehydrogenation	RHEA	34755880
MMDBr0024754	Acetic acid	diphosphate	[Citrate [pro-3S]-lyase] ligase	Ligation	RHEA	34755880
MMDBr0024907	Mannitol	L-Histidine	PTS system mannitol-specific EIICB component	Phosphorylation	RHEA	34755880
MMDBr0024957	Phosphate	2-deoxy-alpha-D-ribose 1-phosphate	Purine nucleoside phosphorylase	Phosphorylation	RHEA	34755880
MMDBr0025013	Phosphate	Glucose 1-phosphate	Maltodextrin phosphorylase	Phosphorylation	RHEA	34755880
MMDBr0025067	L-Serine	diphosphate	Phosphoribosyl-dephospho-CoA transferase	Transfer of phosphoribosyl-dephospho-CoA	RHEA	34755880
MMDBr0025214	(S)-malate(2-)	Oxalacetic acid	Probable malate:quinone oxidoreductase	Redox reaction	RHEA	34755880
MMDBr0025316	N-Acetyl-D-glucosamine	L-Histidine	PTS system N-acetylglucosamine-specific EIICBA component	Phosphorylation	RHEA	34755880
MMDBr0025322	keto-L-sorbose	L-Histidine	PTS system sorbose-specific EIIB component	Not Available	RHEA	34755880
MMDBr0025505	NAD	Hydrogen Ion	Probable tRNA-dihydrouridine synthase	Synthesis	RHEA	34755880
MMDBr0025630	S-Adenosylmethionine	Hydrogen Ion	PqqA peptide cyclase	Cycle formation	RHEA	34755880

Genome Data

Genome Link

MMDBm0001066

Genome Length

5410142 bp

# Predicted Proteins

5660

GenBank Sequence Modification Date

17-FEB-2022

MiMeDB Deposition Date

2022-08-28 03:49:07 UTC

Reference

PMID: 17704766

Source Links

GenBank

NC_016845