| MMDBr0012920 | Dihydroneopterin | 6-Hydroxymethyl dihydropterin | Folic acid synthesis protein fol1 | Aldol addition (or reverse) | RHEA | 34755880 |
| MMDBr0013007 | 6-Hydroxymethyl dihydropterin | 6-Hydroxymethyl-dihydropterin pyrophosphate | Folic acid synthesis protein fol1 | Phosphorylation; Synthesis | RHEA | 34755880 |
| MMDBr0013009 | Fe2+ | Iron(3+) | Cbb3-type cytochrome c oxidase subunit CcoN1 | Oxidation | RHEA | 34755880 |
| MMDBr0013010 | Fe2+ | Iron(3+) | Cytochrome c oxidase subunit 1 | Oxidation | RHEA | 34755880 |
| MMDBr0013034 | Water | Hydrogen Ion | Inosine-5'-monophosphate dehydrogenase | Dehydrogenation | RHEA | 34755880 |
| MMDBr0013081 | (6R)-5,10-methylene-5,6,7,8-tetrahydrofolic acid | 7,8-dihydrofolate monoglutamate | Bifunctional dihydrofolate reductase-thymidylate synthase | Reduction; Synthesis | RHEA | 34755880 |
| MMDBr0013179 | Adenosine triphosphate | ADP | Replicase large subunit | Synthesis of a primer | RHEA | 34755880 |
| MMDBr0013187 | Adenosine triphosphate | Shikimate 3-phosphate | Pentafunctional AROM polypeptide | Phosphorylation | RHEA | 34755880 |
| MMDBr0013331 | (S)-2,3-epoxysqualene | Lanosterin | Lanosterol synthase | Synthesis | RHEA | 34755880 |
| MMDBr0013382 | (6S)-5,6,7,8-tetrahydrofolic acid | 7,8-dihydrofolate monoglutamate | Bifunctional dihydrofolate reductase-thymidylate synthase | Reduction | RHEA | 34755880 |
| MMDBr0013681 | NADP(+) | 3-Dehydroshikimic acid | Pentafunctional AROM polypeptide | Dehydrogenation | RHEA | 34755880 |
| MMDBr0013936 | 6-Hydroxymethyl-dihydropterin pyrophosphate | 7,8-Dihydropteroic acid | Dihydropteroate synthase type-1 | Reduction; Synthesis | RHEA | 34755880 |
| MMDBr0014068 | 3-Dehydroquinate | 3-Dehydroshikimic acid | Catabolic 3-dehydroquinase | Hydration/dehydration of C-O bond; Synthesis | RHEA | 34755880 |
| MMDBr0014083 | Shikimate 3-phosphate | 5-O-(1-Carboxyvinyl)-3-phosphoshikimate | Pentafunctional AROM polypeptide | Synthesis; Dehydration and isomerisation; Oxidation; Phosphorylation; Transfer of a carboxyvinyl group | RHEA | 34755880 |
| MMDBr0014135 | Water | Deoxyadenosine | Adenosylhomocysteinase | Reversible hydrolysis | RHEA | 34755880 |
| MMDBr0014160 | 3-deoxy-D-arabino-heptulosonate-7-phosphate | 3-Dehydroquinate | Pentafunctional AROM polypeptide | Phosphorylation; Synthesis | RHEA | 34755880 |
| MMDBr0024586 | L-Serine | Hydrogen Ion | Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein | Phosphorylation; Synthesis | RHEA | 34755880 |
| MMDBr0024657 | L-Cysteine | Hydrogen Ion | Putative thioredoxin reductase | Reduction | RHEA | 34755880 |
| MMDBr0024701 | Acetyl-CoA | Hydrogen Ion | Histone acetyltransferase rtt109 | N-Acetylation | RHEA | 34755880 |
| MMDBr0024702 | Acetyl-CoA | Hydrogen Ion | Histone acetyltransferase rtt109 | N-Acetylation | RHEA | 34755880 |
| MMDBr0025209 | Acetyl-CoA | Hydrogen Ion | N-acetyltransferase Eis | Acetylation | RHEA | 34755880 |
| MMDBr0025210 | Acetyl-CoA | Hydrogen Ion | Histone acetyltransferase rtt109 | N-Acetylation | RHEA | 34755880 |
| MMDBr0025237 | L-Threonine | Hydrogen Ion | Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein | Phosphorylation; Synthesis | RHEA | 34755880 |
