MiMeDB: Caldicellulosiruptor bescii DSM 6725 (MMDBm0001359)

Microbe Identification

Microbe name

Caldicellulosiruptor bescii DSM 6725

NCBI Taxonomy ID

521460

Microbe Taxonomy

Superkingdom

Bacteria

Kingdom

Eubacteria

Phylum

Firmicutes

Class

Clostridia

Order

Thermoanaerobacterales

Family

Thermoanaerobacterales Family III. Incertae Sedis

Genus

Caldicellulosiruptor

Species

bescii

Strain

Microbe Properties

Gram staining properties

Positive

Shape

Not Available

Mobility

Not Available

Flagellar presence

Not Available

Number of membranes

Not Available

Oxygen preference

Anaerobe

Optimal temperature

Not Available

Temperature range

Thermophilic

Habitat

Specialized

Biotic relationship

Free living

Cell arrangement

Not Available

Sporulation

Not Available

Metabolism

Cellulose degrader

Energy source

Not Available

Host and Biospecimens

Host	Body site	Biospecimen	Details	Data Source	Reference
Human	Gut	Feces	Expected but not quantified

Health Effects

Host	Related Health Condition	Biospecimen	Microbal response/effect	Data Source	Reference

Related Metabolites

Metabolic Reactions

Reactions

Reaction ID	Precursor	Product	Enzyme	Reaction Type	Data Source	Reference
MMDBr0012860	(2R)-2-phosphoglyceric acid	Water	Enolase	Enolization	RHEA	34755880
MMDBr0012895	diphosphate	Phosphoribosyl pyrophosphate	Orotate phosphoribosyltransferase	Transfer of a ribosyl group	RHEA	34755880
MMDBr0012953	(R)-Pantoate	Pantothenic acid	Pantothenate synthetase	Ligation; Phosphorylation; Synthesis	RHEA	34755880
MMDBr0012954	Adenosine triphosphate	Argininosuccinic acid	Argininosuccinate synthase	Synthesis	RHEA	34755880
MMDBr0012970	D-erythro-1-(Imidazol-4-yl)glycerol 3-phosphate	3-(Imidazol-4-yl)-2-oxopropyl phosphate	Imidazoleglycerol-phosphate dehydratase	Hydration/dehydration of C-O bond; Synthesis	RHEA	34755880
MMDBr0012989	Adenosine triphosphate	ADP	D-alanine--D-alanine ligase	Ligation	RHEA	34755880
MMDBr0013001	Acetic acid	Acetyl phosphate	Acetate kinase	Transfer of a formyl group	RHEA	34755880
MMDBr0013026	Hydrogen Ion	Carbon dioxide	Orotidine 5'-phosphate decarboxylase	Decarboxylation	RHEA	34755880
MMDBr0013027	Adenosine triphosphate	ADP	Cytidylate kinase	Phosphorylation	RHEA	34755880
MMDBr0013038	diphosphate	Phosphoribosyl pyrophosphate	Tryptophan biosynthesis protein TrpCD	Transfer of a ribosyl group	RHEA	34755880
MMDBr0013045	Alpha-D-glucose 6-phosphate	beta-D-Fructose 6-phosphate	Glucose-6-phosphate isomerase	Isomerization	RHEA	34755880
MMDBr0013046	(6R)-5,10-methylene-5,6,7,8-tetrahydrofolic acid	(6S)-5,6,7,8-tetrahydrofolic acid	3-methyl-2-oxobutanoate hydroxymethyltransferase	Methylation	RHEA	34755880
MMDBr0013098	NADP(+)	Hydrogen Ion	UDP-N-acetylenolpyruvoylglucosamine reductase	Reduction	RHEA	34755880
MMDBr0013110	D-mannose 6-phosphate	Fructose 6-phosphate	Alginate biosynthesis protein AlgA	Isomerization	RHEA	34755880
MMDBr0013143	Putrescine	Hydrogen Ion	Polyamine aminopropyltransferase	Synthesis	RHEA	34755880
MMDBr0013170	Adenosine monophosphate	ADP	Adenylate kinase	Phosphorylation	RHEA	34755880
MMDBr0013173	diphosphate	Phosphoribosyl pyrophosphate	Bifunctional protein PyrR	Transfer of phosphoribosyl group	RHEA	34755880
MMDBr0013178	D-Glucuronic acid	D-Fructofuranuronic acid	Uronate isomerase	Isomerization	RHEA	34755880
MMDBr0013179	Adenosine triphosphate	ADP	Replicase large subunit	Synthesis of a primer	RHEA	34755880
MMDBr0013187	Adenosine triphosphate	Shikimate 3-phosphate	Pentafunctional AROM polypeptide	Phosphorylation	RHEA	34755880
MMDBr0013212	7-Aminomethyl-7-carbaguanine	7-Cyano-7-carbaguanine	NADPH-dependent 7-cyano-7-deazaguanine reductase	Reduction	RHEA	34755880
MMDBr0013213	2-C-methyl-D-erythritol 4-phosphate	4-(Cytidine 5'-diphospho)-2-C-methyl-D-erythritol	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	Transfer of a cytidylyl group	RHEA	34755880
MMDBr0013221	(R)-2,3-Dihydroxy-3-methylpentanoate	(S)-2-ethyl-2-hydroxy-3-oxobutanoic acid	Ketol-acid reductoisomerase, mitochondrial	Isomerization	RHEA	34755880
MMDBr0013225	L-Dihydroorotic acid	Hydrogen Ion	Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit	Dehydrogenation	RHEA	34755880
MMDBr0013274	Adenosine triphosphate	ADP	Homoserine kinase	Phosphorylation	RHEA	34755880
MMDBr0013295	(S)-4-Amino-5-oxopentanoate	5-Aminolevulinic acid	Glutamate-1-semialdehyde 2,1-aminomutase	Non-hydrolytic bond cleavage (or its reversal)	RHEA	34755880
MMDBr0013333	Adenosine triphosphate	ADP	Protein ARG5,6, mitochondrial	Phosphorylation	RHEA	34755880
MMDBr0013431	1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide	5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase	Isomerization	RHEA	34755880
MMDBr0013458	Guanosine triphosphate	Guanosine diphosphate	Adenylosuccinate synthetase	Synthesis	RHEA	34755880
MMDBr0013464	(7R,8S)-7,8-diammoniononanoic acid	Dethiobiotin	Biotin biosynthesis bifunctional protein BioCD	Amine group addition; Synthesis	RHEA	34755880
MMDBr0013478	Hydrogen Ion	Carbon dioxide	S-adenosylmethionine decarboxylase proenzyme	Decarboxylation	RHEA	34755880
MMDBr0013529	Adenosine triphosphate	ADP	UDP-N-acetylmuramoylalanine--D-glutamate ligase	Ligation	RHEA	34755880
MMDBr0013549	Adenosine monophosphate	Phosphoribosyl pyrophosphate	Adenine phosphoribosyltransferase	Transfer of a ribosyl group	RHEA	34755880
MMDBr0013611	D-Glyceraldehyde 3-phosphate	beta-D-Fructose 6-phosphate	Transaldolase	Transfer of aldol group	RHEA	34755880
MMDBr0013659	Guanosine triphosphate	7,8-dihydroneopterin 3'-triphosphate	Bifunctional protein FolKE	Hydrolysis	RHEA	34755880
MMDBr0013681	NADP(+)	3-Dehydroshikimic acid	Pentafunctional AROM polypeptide	Dehydrogenation	RHEA	34755880
MMDBr0013703	Dihydroxyacetone phosphate	BPG	Methylglyoxal synthase	Synthesis	RHEA	34755880
MMDBr0013768	4-(Cytidine 5'-diphospho)-2-C-methyl-D-erythritol	2-Phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase	Phosphorylation	RHEA	34755880
MMDBr0013770	Water	Phosphoribosyl formamidocarboxamide	Bifunctional purine biosynthesis protein PurH	Hydrolysis; Synthesis	RHEA	34755880
MMDBr0013773	1-(5-phosphoribosyl)-ATP	Phosphoribosyl pyrophosphate	ATP phosphoribosyltransferase	Transfer of a ribosyl group	RHEA	34755880
MMDBr0013792	Adenosine triphosphate	ADP	NAD kinase	Phosphorylation	RHEA	34755880
MMDBr0013884	Hydrogen Ion	beta-Alanine	L-aspartate decarboxylase dtxS4	Decarboxylation	RHEA	34755880
MMDBr0013895	L-Glutamic-gamma-semialdehyde	Hydrogen Ion	Gamma-glutamyl phosphate reductase	Reduction	RHEA	34755880
MMDBr0013908	Guanosine triphosphate	Guanosine diphosphate	GTPase ArgK	Dephosphorylation; Hydrolysis; Nucleic acid synthesis and/or repair	RHEA	34755880
MMDBr0013921	(R)-4'-phosphopantetheine	3'-dephospho-CoA	Phosphopantetheine adenylyltransferase	Dephosphorylation	RHEA	34755880
MMDBr0013946	Carbamoylphosphate	Hydrogen Ion	Protein pyrABCN	Transfer of a carbamoyl group	RHEA	34755880
MMDBr0013966	(6S)-5,6,7,8-tetrahydrofolic acid	(6S)-10-formyltetrahydrofolic acid	C-1-tetrahydrofolate synthase, cytoplasmic	Ligation; Synthesis	RHEA	34755880
MMDBr0014061	5-O-(1-Carboxyvinyl)-3-phosphoshikimate	Chorismate	Chorismate synthase	Synthesis	RHEA	34755880
MMDBr0014068	3-Dehydroquinate	3-Dehydroshikimic acid	Catabolic 3-dehydroquinase	Hydration/dehydration of C-O bond; Synthesis	RHEA	34755880
MMDBr0014083	Shikimate 3-phosphate	5-O-(1-Carboxyvinyl)-3-phosphoshikimate	Pentafunctional AROM polypeptide	Synthesis; Dehydration and isomerisation; Oxidation; Phosphorylation; Transfer of a carboxyvinyl group	RHEA	34755880
MMDBr0014117	N-Acetyl-L-glutamate 5-semialdehyde	Hydrogen Ion	Protein ARG5,6, mitochondrial	Reduction	RHEA	34755880
MMDBr0014167	(R)-2,3-Dihydroxy-isovalerate	(2S)-2-acetolactic acid	Ketol-acid reductoisomerase, mitochondrial	Isomerization	RHEA	34755880
MMDBr0014180	(6S)-10-formyltetrahydrofolic acid	(6S)-5,6,7,8-tetrahydrofolic acid	Bifunctional purine biosynthesis protein PurH	Synthesis	RHEA	34755880
MMDBr0014193	2-Methyl-4-amino-5-hydroxymethylpyrimidine diphosphate	diphosphate	Probable thiamine biosynthetic bifunctional enzyme	Synthesis	RHEA	34755880
MMDBr0014254	D-Xylose	D-Xylulose	Xylose isomerase	Isomerization	RHEA	34755880
MMDBr0014257	Adenosine triphosphate	Nicotinic acid adenine dinucleotide	Probable nicotinate-nucleotide adenylyltransferase	Reversible transfer of an adenylyl group	RHEA	34755880
MMDBr0014282	2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine	5-Aminoimidazole ribonucleotide	Bifunctional purine biosynthetic protein ADE5,7	Ligation	RHEA	34755880
MMDBr0014323	Adenosine triphosphate	ADP	Bifunctional enzyme MurC/Ddl	Ligation	RHEA	34755880
MMDBr0014333	alpha-D-Glucosamine 1-phosphate	D-glucosamine 6-phosphate	Phosphoglucosamine mutase	Intramolecular transfer of functional group	RHEA	34755880
MMDBr0014392	2-Phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol	2-C-Methyl-D-erythritol-2,4-cyclodiphosphate	Bifunctional enzyme IspD/IspF	Synthesis	RHEA	34755880
MMDBr0014393	5-Dehydro-4-deoxy-D-glucuronate	(4S)-4,6-Dihydroxy-2,5-dioxohexanoate	4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase	Isomerization	RHEA	34755880
MMDBr0014407	Argininosuccinic acid	fumarate	Bifunctional protein ArgHA	Non-hydrolytic bond cleavage (or its reversal)	RHEA	34755880
MMDBr0014437	L-Dihydroorotic acid	Hydrogen Ion	Dihydroorotase	Hydrolysis	RHEA	34755880
MMDBr0014486	(R)-2,3-Dihydroxy-isovalerate	alpha-Ketoisovaleric acid	Dihydroxy-acid dehydratase, mitochondrial	Hydration/dehydration of C-O bond	RHEA	34755880
MMDBr0014487	(R)-2,3-Dihydroxy-isovalerate	alpha-Ketoisovaleric acid	Dihydroxy-acid dehydratase, mitochondrial	Hydration/dehydration of C-O bond	RHEA	34755880
MMDBr0014514	Adenosine triphosphate	ADP	Cytidylate kinase	Phosphorylation	RHEA	34755880
MMDBr0014596	Dihydroxyacetone phosphate	Hydrogen Ion	Quinolinate synthase	Synthesis	RHEA	34755880
MMDBr0014597	Dihydroxyacetone phosphate	Hydrogen Ion	Quinolinate synthase	Synthesis	RHEA	34755880
MMDBr0014619	L-3,4-Dihydroxybutan-2-one 4-phosphate	6,7-Dimethyl-8-(1-D-ribityl)lumazine	6,7-dimethyl-8-ribityllumazine synthase	Synthesis	RHEA	34755880
MMDBr0014718	(R)-2,3-Dihydroxy-3-methylpentanoate	2-Keto-3-methyl-valerate	Dihydroxy-acid dehydratase, mitochondrial	Hydration/dehydration of C-O bond	RHEA	34755880
MMDBr0014719	(R)-2,3-Dihydroxy-3-methylpentanoate	2-Keto-3-methyl-valerate	Dihydroxy-acid dehydratase, mitochondrial	Hydration/dehydration of C-O bond	RHEA	34755880
MMDBr0014720	D-Galacturonate	D-Tagaturonate	Uronate isomerase	Isomerization	RHEA	34755880
MMDBr0014763	7-Deaza-7-carboxyguanine	7-Cyano-7-carbaguanine	7-cyano-7-deazaguanine synthase	Synthesis	RHEA	34755880
MMDBr0014783	di-trans,octa-cis-undecaprenyl diphosphate	di-trans,octa-cis-undecaprenyl phosphate	Undecaprenyl-diphosphatase BcrC	Dephosphorylation	RHEA	34755880
MMDBr0014825	di-trans,octa-cis-undecaprenyl phosphate	di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine	Phospho-N-acetylmuramoyl-pentapeptide-transferase	Transfer of phospho-N-acetylmuramoyl-pentapeptide	RHEA	34755880
MMDBr0014846	Thymidine 5'-triphosphate	diphosphate	dTTP/UTP pyrophosphatase	Dephosphorylation	RHEA	34755880
MMDBr0014908	Water	diphosphate	dTTP/UTP pyrophosphatase	Dephosphorylation	RHEA	34755880
MMDBr0017950	aldehydo-D-ribose 5-phosphate	Hydrogen Ion	Pyridoxal 5'-phosphate synthase subunit PDX1	Synthesis	RHEA	34755880
MMDBr0015136	3-Isopropylmalate	2-Isopropylmalic acid	3-isopropylmalate dehydratase large subunit gloJ	Isomerization	RHEA	34755880
MMDBr0015316	L-Aspartate-semialdehyde	(2S,4S)-4-Hydroxy-2,3,4,5-tetrahydrodipicolinate	4-hydroxy-tetrahydrodipicolinate synthase	Synthesis	RHEA	34755880
MMDBr0016358	2-[(2R,5Z)-2-Carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate	Carbon dioxide	Probable thiamine biosynthetic bifunctional enzyme	Synthesis	RHEA	34755880
MMDBr0016359	2-(2-Carboxy-4-methylthiazol-5-yl)ethyl phosphate	Carbon dioxide	Probable thiamine biosynthetic bifunctional enzyme	Synthesis	RHEA	34755880
MMDBr0016813	2-Aminobenzoic acid	2-(4-dimethylaminophenyl)diazenylbenzoic acid	FMN-dependent NADPH-azoreductase	Reduction	RHEA	34755880
MMDBr0016907	Adenosine triphosphate	ADP	ATP synthase subunit alpha	ATP hydrolysis; Synthesis	RHEA	34755880
MMDBr0017834	(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate	D-Glyceraldehyde 3-phosphate	Tryptophan synthase	Synthesis	RHEA	34755880
MMDBr0017843	Adenosine triphosphate	Adenosine monophosphate	GMP synthase [glutamine-hydrolyzing]	Synthesis	RHEA	34755880
MMDBr0017871	(6R)-5,10-methylene-5,6,7,8-tetrahydrofolic acid	(6S)-5,6,7,8-tetrahydrofolic acid	Serine hydroxymethyltransferase	Methylation	RHEA	34755880
MMDBr0017874	Water	L-Glutamic acid	Thermolabile glutaminase	Synthesis	RHEA	34755880
MMDBr0017897	Adenosine triphosphate	diphosphate	S-adenosylmethionine synthase	Synthesis	RHEA	34755880
MMDBr0024368	Adenosine triphosphate	diphosphate	Isoleucine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024401	L-Serine	Hydrogen Ion	Holo-[acyl-carrier-protein] synthase	Dehydrogenation; Synthesis	RHEA	34755880
MMDBr0024411	Adenosine triphosphate	Hydrogen Ion	Type-2 serine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024415	(S)-4-Amino-5-oxopentanoate	Hydrogen Ion	Glutamyl-tRNA reductase	Reduction	RHEA	34755880
MMDBr0024474	Adenosine triphosphate	diphosphate	Proline--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024483	Water	Hydrogen Ion	Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C	Amide group addition	RHEA	34755880
MMDBr0024539	Hydrogen Ion	5'-Deoxyadenosine	Lipoyl synthase	Synthesis	RHEA	34755880
MMDBr0024546	Hydrogen Ion	(6S)-5,6,7,8-tetrahydrofolic acid	Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO	Methylation	RHEA	34755880
MMDBr0024559	Adenosine triphosphate	Hydrogen Ion	Histidine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024568	Water	Hydrogen Ion	Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C	Amide group addition	RHEA	34755880
MMDBr0024578	Adenosine triphosphate	diphosphate	Cysteine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024593	ADP-alpha-D-glucose	Hydrogen Ion	Probable glycogen synthase	Synthesis	RHEA	34755880
MMDBr0024628	Adenosine triphosphate	Hydrogen Ion	Phenylalanine--tRNA ligase beta subunit	Ligation	RHEA	34755880
MMDBr0024707	di-mu-Sulfido-diiron(1+)	5'-Deoxyadenosine	Biotin synthase	Synthesis	RHEA	34755880
MMDBr0024779	Water	formate	Peptide deformylase 1	Removal of the N-terminal formyl group	RHEA	34755880
MMDBr0024813	Dimethylallylpyrophosphate	diphosphate	tRNA dimethylallyltransferase	Transfer of a dimethylallyl group	RHEA	34755880
MMDBr0024971	L-Threonylcarbamoyladenylate	Hydrogen Ion	tRNA N6-adenosine threonylcarbamoyltransferase	Synthesis	RHEA	34755880
MMDBr0025060	Adenosine triphosphate	Hydrogen Ion	Type-2 serine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0025085	S-Adenosylmethionine	Hydrogen Ion	Putative ribosomal RNA large subunit methyltransferase H	Methylation	RHEA	34755880
MMDBr0025105	S-Adenosylmethionine	Hydrogen Ion	Ribosomal RNA small subunit methyltransferase H	Methylation	RHEA	34755880
MMDBr0025235	L-Serine	Hydrogen Ion	HPr kinase/phosphorylase	Phosphorylation	RHEA	34755880
MMDBr0025236	Hydrogen Ion	L-Serine	HPr kinase/phosphorylase	Phosphorylation	RHEA	34755880
MMDBr0025490	S-Adenosylmethionine	Hydrogen Ion	Ribosomal protein L11 methyltransferase	Methylation	RHEA	34755880
MMDBr0025656	Acetic acid	diphosphate	tRNA(Met) cytidine acetate ligase	Ligation	RHEA	34755880
MMDBr0025777	Hydrogen Ion	(6S)-5,6,7,8-tetrahydrofolic acid	Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO	Methylation	RHEA	34755880
MMDBr0025921	Hydrogen Ion	NAD	FMN-dependent NADH:quinone oxidoreductase	Redox reaction	RHEA	34755880
MMDBr0026014	Phosphate	Uridine 5'-diphosphate	Ribonuclease PH	RNA degradation	RHEA	34755880
MMDBr0026015	Phosphate	Uridine 5'-diphosphate	Ribonuclease PH	RNA degradation	RHEA	34755880
MMDBr0026016	Phosphate	Guanosine 3',5'-bis(diphosphate)	Ribonuclease PH	RNA degradation	RHEA	34755880
MMDBr0026017	Phosphate	Adenosine diphosphate	Ribonuclease PH	RNA degradation	RHEA	34755880

Genome Data

Genome Link

Not Available

Genome Length

Not Available

# Predicted Proteins

GenBank Sequence Modification Date

17-FEB-2022

MiMeDB Deposition Date

Reference

PMID: 17704766

Source Links

GenBank