MiMeDB: Lawsonia intracellularis PHE/MN1-00 (MMDBm0001767)

Microbe Identification

Microbe name

Lawsonia intracellularis PHE/MN1-00

NCBI Taxonomy ID

363253

Microbe Taxonomy

Superkingdom

Bacteria

Kingdom

Eubacteria

Phylum

Proteobacteria

Class

Deltaproteobacteria

Order

Desulfovibrionales

Family

Desulfovibrionaceae

Genus

Lawsonia

Species

intracellularis

Strain

Not Available

Microbe Properties

Gram staining properties

Positive

Shape

Bacilli

Mobility

Flagellar presence

Number of membranes

Not Available

Oxygen preference

Facultative

Optimal temperature

Temperature range

Mesophilic

Habitat

HostAssociated

Biotic relationship

Free living

Cell arrangement

Not Available

Sporulation

Not Available

Metabolism

Not Available

Energy source

Not Available

Host and Biospecimens

Host	Body site	Biospecimen	Details	Data Source	Reference
Pig			Unknown

Health Effects

Host	Related Health Condition	Biospecimen	Microbal response/effect	Data Source	Reference

Related Metabolites

Metabolic Reactions

Reactions

Reaction ID	Precursor	Product	Enzyme	Reaction Type	Data Source	Reference
MMDBr0012860	(2R)-2-phosphoglyceric acid	Water	Enolase	Enolization	RHEA	34755880
MMDBr0012954	Adenosine triphosphate	Argininosuccinic acid	Argininosuccinate synthase	Synthesis	RHEA	34755880
MMDBr0012971	beta-D-Fructose 1,6-bisphosphate	beta-D-Fructose 6-phosphate	Fructose-1,6-bisphosphatase/inositol-1-monophosphatase	Aldol addition (or reverse); Dephosphorylation	RHEA	34755880
MMDBr0012975	NAD	Dihydroxyacetone phosphate	Glycerol-3-phosphate dehydrogenase [NAD(+)]	Dehydrogenation	RHEA	34755880
MMDBr0012976	NADP(+)	Dihydroxyacetone phosphate	Glycerol-3-phosphate dehydrogenase [NAD(P)+]	Dehydrogenation	RHEA	34755880
MMDBr0012989	Adenosine triphosphate	ADP	D-alanine--D-alanine ligase	Ligation	RHEA	34755880
MMDBr0013001	Acetic acid	Acetyl phosphate	Acetate kinase	Transfer of a formyl group	RHEA	34755880
MMDBr0013026	Hydrogen Ion	Carbon dioxide	Orotidine 5'-phosphate decarboxylase	Decarboxylation	RHEA	34755880
MMDBr0013027	Adenosine triphosphate	ADP	Cytidylate kinase	Phosphorylation	RHEA	34755880
MMDBr0013134	D-Glyceraldehyde 3-phosphate	1-Deoxy-D-xylulose 5-phosphate	1-deoxy-D-xylulose-5-phosphate synthase	Synthesis	RHEA	34755880
MMDBr0013170	Adenosine monophosphate	ADP	Adenylate kinase	Phosphorylation	RHEA	34755880
MMDBr0013179	Adenosine triphosphate	ADP	Replicase large subunit	Synthesis of a primer	RHEA	34755880
MMDBr0013194	Water	Hydroxymethylbilane	Porphobilinogen deaminase	Deamination	RHEA	34755880
MMDBr0013213	2-C-methyl-D-erythritol 4-phosphate	4-(Cytidine 5'-diphospho)-2-C-methyl-D-erythritol	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	Transfer of a cytidylyl group	RHEA	34755880
MMDBr0013224	Hydrogen Ion	diphosphate	Bifunctional protein GlmU	N-Acetylation; Phosphorylation; Isomerization	RHEA	34755880
MMDBr0013226	Adenosine triphosphate	ADP	Putative thymidylate kinase	Phosphorylation	RHEA	34755880
MMDBr0013246	2-C-methyl-D-erythritol 4-phosphate	1-Deoxy-D-xylulose 5-phosphate	1-deoxy-D-xylulose 5-phosphate reductoisomerase	Isomerization	RHEA	34755880
MMDBr0013248	Acetyl-CoA	CoA	Bifunctional protein GlmU	N-Acetylation	RHEA	34755880
MMDBr0013295	(S)-4-Amino-5-oxopentanoate	5-Aminolevulinic acid	Glutamate-1-semialdehyde 2,1-aminomutase	Non-hydrolytic bond cleavage (or its reversal)	RHEA	34755880
MMDBr0013333	Adenosine triphosphate	ADP	Protein ARG5,6, mitochondrial	Phosphorylation	RHEA	34755880
MMDBr0013458	Guanosine triphosphate	Guanosine diphosphate	Adenylosuccinate synthetase	Synthesis	RHEA	34755880
MMDBr0013464	(7R,8S)-7,8-diammoniononanoic acid	Dethiobiotin	Biotin biosynthesis bifunctional protein BioCD	Amine group addition; Synthesis	RHEA	34755880
MMDBr0013470	(2R)-2-phosphoglyceric acid	(2R)-3-phosphoglyceric acid	2,3-bisphosphoglycerate-independent phosphoglycerate mutase	Intramolecular transfer of functional group	RHEA	34755880
MMDBr0013526	Pantothenic acid	(R)-4'-phosphopantothenic acid	Bifunctional enzyme BirA/CoaX	Phosphorylation	RHEA	34755880
MMDBr0013529	Adenosine triphosphate	ADP	UDP-N-acetylmuramoylalanine--D-glutamate ligase	Ligation	RHEA	34755880
MMDBr0013547	Adenosine triphosphate	ADP	CTP synthase	Synthesis	RHEA	34755880
MMDBr0013659	Guanosine triphosphate	7,8-dihydroneopterin 3'-triphosphate	Bifunctional protein FolKE	Hydrolysis	RHEA	34755880
MMDBr0013768	4-(Cytidine 5'-diphospho)-2-C-methyl-D-erythritol	2-Phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase	Phosphorylation	RHEA	34755880
MMDBr0013784	D-Glyceraldehyde 3-phosphate	Dihydroxyacetone phosphate	Bifunctional PGK/TIM	Isomerization	RHEA	34755880
MMDBr0013792	Adenosine triphosphate	ADP	NAD kinase	Phosphorylation	RHEA	34755880
MMDBr0013801	Phosphoenolpyruvic acid	Phosphate	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	Synthesis	RHEA	34755880
MMDBr0013908	Guanosine triphosphate	Guanosine diphosphate	GTPase ArgK	Dephosphorylation; Hydrolysis; Nucleic acid synthesis and/or repair	RHEA	34755880
MMDBr0013921	(R)-4'-phosphopantetheine	3'-dephospho-CoA	Phosphopantetheine adenylyltransferase	Dephosphorylation	RHEA	34755880
MMDBr0013946	Carbamoylphosphate	Hydrogen Ion	Protein pyrABCN	Transfer of a carbamoyl group	RHEA	34755880
MMDBr0013966	(6S)-5,6,7,8-tetrahydrofolic acid	(6S)-10-formyltetrahydrofolic acid	C-1-tetrahydrofolate synthase, cytoplasmic	Ligation; Synthesis	RHEA	34755880
MMDBr0013970	L-Alanine	D-Alanine	L-alanine/L-glutamate racemase	Racemization	RHEA	34755880
MMDBr0014024	Hydrogen Ion	Ammonium	5'-deoxyadenosine deaminase	Deamination	RHEA	34755880
MMDBr0014035	Adenosine triphosphate	ADP	Guanylate kinase	Phosphorylation	RHEA	34755880
MMDBr0014193	2-Methyl-4-amino-5-hydroxymethylpyrimidine diphosphate	diphosphate	Probable thiamine biosynthetic bifunctional enzyme	Synthesis	RHEA	34755880
MMDBr0014251	(6R)-5,10-methylene-5,6,7,8-tetrahydrofolic acid	5,10-Methenyltetrahydrofolate	C-1-tetrahydrofolate synthase, cytoplasmic	Synthesis	RHEA	34755880
MMDBr0014282	2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine	5-Aminoimidazole ribonucleotide	Bifunctional purine biosynthetic protein ADE5,7	Ligation	RHEA	34755880
MMDBr0014323	Adenosine triphosphate	ADP	Bifunctional enzyme MurC/Ddl	Ligation	RHEA	34755880
MMDBr0014333	alpha-D-Glucosamine 1-phosphate	D-glucosamine 6-phosphate	Phosphoglucosamine mutase	Intramolecular transfer of functional group	RHEA	34755880
MMDBr0014337	3-deoxy-D-manno-2-octulosonate	CMP-3-deoxy-beta-D-manno-octulosonate	3-deoxy-manno-octulosonate cytidylyltransferase	Transfer of a cytidylyl group	RHEA	34755880
MMDBr0014366	Adenosine triphosphate	ADP	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase	Ligation	RHEA	34755880
MMDBr0014369	5,10-Methenyltetrahydrofolate	(6S)-10-formyltetrahydrofolic acid	C-1-tetrahydrofolate synthase, cytoplasmic	Reversible cyclization	RHEA	34755880
MMDBr0014392	2-Phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol	2-C-Methyl-D-erythritol-2,4-cyclodiphosphate	Bifunctional enzyme IspD/IspF	Synthesis	RHEA	34755880
MMDBr0014405	LL-2,6-Diaminoheptanedioate	(S)-2,3,4,5-tetrahydrodipicolinate	LL-diaminopimelate aminotransferase	Amine group addition	RHEA	34755880
MMDBr0014407	Argininosuccinic acid	fumarate	Bifunctional protein ArgHA	Non-hydrolytic bond cleavage (or its reversal)	RHEA	34755880
MMDBr0014447	Adenosine triphosphate	ADP	UMP-CMP kinase	Phosphorylation	RHEA	34755880
MMDBr0014505	Hydrogen Ion	Ammonium	5'-deoxyadenosine deaminase	Deamination	RHEA	34755880
MMDBr0014514	Adenosine triphosphate	ADP	Cytidylate kinase	Phosphorylation	RHEA	34755880
MMDBr0014619	L-3,4-Dihydroxybutan-2-one 4-phosphate	6,7-Dimethyl-8-(1-D-ribityl)lumazine	6,7-dimethyl-8-ribityllumazine synthase	Synthesis	RHEA	34755880
MMDBr0017926	Adenosine triphosphate	ADP	CTP synthase	Synthesis	RHEA	34755880
MMDBr0014763	7-Deaza-7-carboxyguanine	7-Cyano-7-carbaguanine	7-cyano-7-deazaguanine synthase	Synthesis	RHEA	34755880
MMDBr0014783	di-trans,octa-cis-undecaprenyl diphosphate	di-trans,octa-cis-undecaprenyl phosphate	Undecaprenyl-diphosphatase BcrC	Dephosphorylation	RHEA	34755880
MMDBr0014825	di-trans,octa-cis-undecaprenyl phosphate	di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine	Phospho-N-acetylmuramoyl-pentapeptide-transferase	Transfer of phospho-N-acetylmuramoyl-pentapeptide	RHEA	34755880
MMDBr0014846	Thymidine 5'-triphosphate	diphosphate	dTTP/UTP pyrophosphatase	Dephosphorylation	RHEA	34755880
MMDBr0014908	Water	diphosphate	dTTP/UTP pyrophosphatase	Dephosphorylation	RHEA	34755880
MMDBr0015026	di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine	di-trans-octa-cis-undecaprenyl diphospho-[N-acetyl-alpha-D-glucosaminyl-(1->4)]-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine	UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase	UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase 1; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase 2; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase 3	RHEA	34755880
MMDBr0015316	L-Aspartate-semialdehyde	(2S,4S)-4-Hydroxy-2,3,4,5-tetrahydrodipicolinate	4-hydroxy-tetrahydrodipicolinate synthase	Synthesis	RHEA	34755880
MMDBr0015402	(S)-2,3,4,5-tetrahydrodipicolinate	(2S,4S)-4-Hydroxy-2,3,4,5-tetrahydrodipicolinate	4-hydroxy-tetrahydrodipicolinate reductase	Reduction	RHEA	34755880
MMDBr0015405	(S)-2,3,4,5-tetrahydrodipicolinate	(2S,4S)-4-Hydroxy-2,3,4,5-tetrahydrodipicolinate	4-hydroxy-tetrahydrodipicolinate reductase	Reduction	RHEA	34755880
MMDBr0015916	1-Hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	2-C-Methyl-D-erythritol-2,4-cyclodiphosphate	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin)	Synthesis	RHEA	34755880
MMDBr0016358	2-[(2R,5Z)-2-Carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate	Carbon dioxide	Probable thiamine biosynthetic bifunctional enzyme	Synthesis	RHEA	34755880
MMDBr0016359	2-(2-Carboxy-4-methylthiazol-5-yl)ethyl phosphate	Carbon dioxide	Probable thiamine biosynthetic bifunctional enzyme	Synthesis	RHEA	34755880
MMDBr0016907	Adenosine triphosphate	ADP	ATP synthase subunit alpha	ATP hydrolysis; Synthesis	RHEA	34755880
MMDBr0017871	(6R)-5,10-methylene-5,6,7,8-tetrahydrofolic acid	(6S)-5,6,7,8-tetrahydrofolic acid	Serine hydroxymethyltransferase	Methylation	RHEA	34755880
MMDBr0017874	Water	L-Glutamic acid	Thermolabile glutaminase	Synthesis	RHEA	34755880
MMDBr0017882	Adenosine triphosphate	ADP	Carbamoyl-phosphate synthase small chain	Synthesis	RHEA	34755880
MMDBr0024368	Adenosine triphosphate	diphosphate	Isoleucine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024371	Adenosine triphosphate	Hydrogen Ion	Asparagine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024389	Adenosine triphosphate	diphosphate	Leucine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024415	(S)-4-Amino-5-oxopentanoate	Hydrogen Ion	Glutamyl-tRNA reductase	Reduction	RHEA	34755880
MMDBr0024418	Adenosine triphosphate	diphosphate	Alanine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024424	S-Adenosylmethionine	S-Adenosylhomocysteine	Protein-L-isoaspartate O-methyltransferase	Methylation	RHEA	34755880
MMDBr0024474	Adenosine triphosphate	diphosphate	Proline--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024483	Water	Hydrogen Ion	Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C	Amide group addition	RHEA	34755880
MMDBr0024522	Adenosine triphosphate	diphosphate	Glycine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024533	Water	Ammonium	Probable chemoreceptor glutamine deamidase CheD	Deamidation	RHEA	34755880
MMDBr0024546	Hydrogen Ion	(6S)-5,6,7,8-tetrahydrofolic acid	Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO	Methylation	RHEA	34755880
MMDBr0024568	Water	Hydrogen Ion	Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C	Amide group addition	RHEA	34755880
MMDBr0024578	Adenosine triphosphate	diphosphate	Cysteine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024590	Adenosine triphosphate	ADP	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0024628	Adenosine triphosphate	Hydrogen Ion	Phenylalanine--tRNA ligase beta subunit	Ligation	RHEA	34755880
MMDBr0024630	S-Adenosylmethionine	Hydrogen Ion	Ribosomal RNA small subunit methyltransferase A	Methylation	RHEA	34755880
MMDBr0024656	Adenosine triphosphate	diphosphate	Arginine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024706	Water	Hydrogen Ion	Hydroxylamine reductase	Reduction	RHEA	34755880
MMDBr0024707	di-mu-Sulfido-diiron(1+)	5'-Deoxyadenosine	Biotin synthase	Synthesis	RHEA	34755880
MMDBr0024745	L-Glutamic acid	diphosphate	Glutamate--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024765	7-Aminomethyl-7-carbaguanine	Guanine	Putative queuine tRNA-ribosyltransferase	Transfer of a ribosyl group	RHEA	34755880
MMDBr0024787	Adenosine triphosphate	Hydrogen Ion	Threonine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024813	Dimethylallylpyrophosphate	diphosphate	tRNA dimethylallyltransferase	Transfer of a dimethylallyl group	RHEA	34755880
MMDBr0024925	Glycerol 3-phosphate	Phosphate	Glycerol-3-phosphate acyltransferase	Acylation	RHEA	34755880
MMDBr0024971	L-Threonylcarbamoyladenylate	Hydrogen Ion	tRNA N6-adenosine threonylcarbamoyltransferase	Synthesis	RHEA	34755880
MMDBr0024974	S-Adenosylmethionine	Hydrogen Ion	tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase	Synthesis	RHEA	34755880
MMDBr0024977	S-Adenosylmethionine	Hydrogen Ion	Ribosomal protein S12 methylthiotransferase RimO	Methylthiolation	RHEA	34755880
MMDBr0025075	S-Adenosylmethionine	Hydrogen Ion	Ribosomal RNA large subunit methyltransferase E	Methylation	RHEA	34755880
MMDBr0025078	S-Adenosylmethionine	S-Adenosylhomocysteine	Ribosomal RNA small subunit methyltransferase G	Methylation	RHEA	34755880
MMDBr0025085	S-Adenosylmethionine	Hydrogen Ion	Putative ribosomal RNA large subunit methyltransferase H	Methylation	RHEA	34755880
MMDBr0025102	di-mu-Sulfido-diiron(1+)	5'-Deoxyadenosine	Ribosomal RNA large subunit methyltransferase N	Methylation	RHEA	34755880
MMDBr0025105	S-Adenosylmethionine	Hydrogen Ion	Ribosomal RNA small subunit methyltransferase H	Methylation	RHEA	34755880
MMDBr0025145	di-mu-Sulfido-diiron(1+)	5'-Deoxyadenosine	Probable dual-specificity RNA methyltransferase RlmN	Methylation	RHEA	34755880
MMDBr0025193	Adenosine triphosphate	ADP	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0025258	Adenosine triphosphate	Hydrogen Ion	tRNA-specific 2-thiouridylase MnmA	2-Thiolation of uridine	RHEA	34755880
MMDBr0025777	Hydrogen Ion	(6S)-5,6,7,8-tetrahydrofolic acid	Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO	Methylation	RHEA	34755880
MMDBr0026022	Adenosine monophosphate	Adenosine	5'-nucleotidase SurE	Hydrolysis of nucleotide; Dephosphorylation	RHEA	34755880
MMDBr0026023	Cytidine monophosphate	Adenosine	5'-nucleotidase SurE	Hydrolysis of nucleotide; Dephosphorylation	RHEA	34755880
MMDBr0026024	Uridine 5'-monophosphate	Uridine	5'-nucleotidase SurE	Hydrolysis of nucleotide; Dephosphorylation	RHEA	34755880
MMDBr0026025	Guanosine monophosphate	Guanosine	5'-nucleotidase SurE	Hydrolysis of nucleotide; Dephosphorylation	RHEA	34755880
MMDBr0026046	Uridine 5'-diphosphate	Uridine triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026047	Uridine 5'-diphosphate	Cytidine triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026048	Guanosine 3',5'-bis(diphosphate)	Guanosine triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026085	Deoxyuridine-5'-diphosphate	Deoxyuridine triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026086	2'-Deoxycytidine 5'-diphosphate	Deoxycytidine 5'-triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026087	2'-Deoxyadenosine 5'-diphosphate	Deoxyadenosine triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026088	2'-Deoxyguanosine 5'-diphosphate	2'-Deoxyguanosine 5'-triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880

Genome Data

Genome Link

Not Available

Genome Length

Not Available

# Predicted Proteins

GenBank Sequence Modification Date

17-FEB-2022

MiMeDB Deposition Date

Reference

PMID: 17704766

Source Links

GenBank