MiMeDB: Methanosaeta thermophila PT (MMDBm0001840)

Microbe Identification

Microbe name

Methanosaeta thermophila PT

NCBI Taxonomy ID

349307

Microbe Taxonomy

Superkingdom

Archaea

Kingdom

Archaea

Phylum

Euryarchaeota

Class

Methanomicrobia

Order

Methanosarcinales

Family

Methanosaetaceae

Genus

Methanosaeta

Species

thermophila

Strain

Microbe Properties

Gram staining properties

Positive

Shape

Not Available

Mobility

Flagellar presence

Number of membranes

Oxygen preference

Anaerobe

Optimal temperature

Not Available

Temperature range

Thermophilic

Habitat

Fresh water - Rice paddies - Sediment

Biotic relationship

Free living

Cell arrangement

Not Available

Sporulation

Nonsporulating

Metabolism

Methanogen - Acetotrophic

Energy source

Lithotroph

Host and Biospecimens

Host	Body site	Biospecimen	Details	Data Source	Reference
Human	Gut	Feces	Expected but not quantified

Health Effects

Host	Related Health Condition	Biospecimen	Microbal response/effect	Data Source	Reference

Related Metabolites

Metabolic Reactions

Reactions

Reaction ID	Precursor	Product	Enzyme	Reaction Type	Data Source	Reference
MMDBr0012860	(2R)-2-phosphoglyceric acid	Water	Enolase	Enolization	RHEA	34755880
MMDBr0013027	Adenosine triphosphate	ADP	Cytidylate kinase	Phosphorylation	RHEA	34755880
MMDBr0013170	Adenosine monophosphate	ADP	Adenylate kinase	Phosphorylation	RHEA	34755880
MMDBr0013187	Adenosine triphosphate	Shikimate 3-phosphate	Pentafunctional AROM polypeptide	Phosphorylation	RHEA	34755880
MMDBr0013221	(R)-2,3-Dihydroxy-3-methylpentanoate	(S)-2-ethyl-2-hydroxy-3-oxobutanoic acid	Ketol-acid reductoisomerase, mitochondrial	Isomerization	RHEA	34755880
MMDBr0013295	(S)-4-Amino-5-oxopentanoate	5-Aminolevulinic acid	Glutamate-1-semialdehyde 2,1-aminomutase	Non-hydrolytic bond cleavage (or its reversal)	RHEA	34755880
MMDBr0013309	Phosphoglycolic acid	Glycolic acid	Phosphoglycolate phosphatase	Dephosphorylation	RHEA	34755880
MMDBr0013333	Adenosine triphosphate	ADP	Protein ARG5,6, mitochondrial	Phosphorylation	RHEA	34755880
MMDBr0013422	LL-2,6-Diaminoheptanedioate	Meso-2,6-Diaminoheptanedioate	Diaminopimelate epimerase	Epimerization; Racemization	RHEA	34755880
MMDBr0013431	1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide	5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase	Isomerization	RHEA	34755880
MMDBr0013458	Guanosine triphosphate	Guanosine diphosphate	Adenylosuccinate synthetase	Synthesis	RHEA	34755880
MMDBr0013470	(2R)-2-phosphoglyceric acid	(2R)-3-phosphoglyceric acid	2,3-bisphosphoglycerate-independent phosphoglycerate mutase	Intramolecular transfer of functional group	RHEA	34755880
MMDBr0013547	Adenosine triphosphate	ADP	CTP synthase	Synthesis	RHEA	34755880
MMDBr0013633	Adenosine triphosphate	diphosphate	Probable FAD synthase	Phosphorylation; Synthesis	RHEA	34755880
MMDBr0013681	NADP(+)	3-Dehydroshikimic acid	Pentafunctional AROM polypeptide	Dehydrogenation	RHEA	34755880
MMDBr0013708	diphosphate	Phosphoribosyl pyrophosphate	Hypoxanthine-guanine phosphoribosyltransferase	Transfer of phosphoribosyl group; Synthesis	RHEA	34755880
MMDBr0013728	(2E,6E,10E)-geranylgeranyl diphosphate	2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate	Digeranylgeranylglyceryl phosphate synthase	Synthesis	RHEA	34755880
MMDBr0013770	Water	Phosphoribosyl formamidocarboxamide	Bifunctional purine biosynthesis protein PurH	Hydrolysis; Synthesis	RHEA	34755880
MMDBr0013884	Hydrogen Ion	beta-Alanine	L-aspartate decarboxylase dtxS4	Decarboxylation	RHEA	34755880
MMDBr0013946	Carbamoylphosphate	Hydrogen Ion	Protein pyrABCN	Transfer of a carbamoyl group	RHEA	34755880
MMDBr0013952	1-(5-phosphoribosyl)-5'-AMP	1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide	Histidine biosynthesis bifunctional protein HisIE	Hydrolysis; Synthesis	RHEA	34755880
MMDBr0014024	Hydrogen Ion	Ammonium	5'-deoxyadenosine deaminase	Deamination	RHEA	34755880
MMDBr0014025	Hydrogen Ion	Ammonium	5'-deoxyadenosine deaminase	Deamination	RHEA	34755880
MMDBr0014061	5-O-(1-Carboxyvinyl)-3-phosphoshikimate	Chorismate	Chorismate synthase	Synthesis	RHEA	34755880
MMDBr0014068	3-Dehydroquinate	3-Dehydroshikimic acid	Catabolic 3-dehydroquinase	Hydration/dehydration of C-O bond; Synthesis	RHEA	34755880
MMDBr0014083	Shikimate 3-phosphate	5-O-(1-Carboxyvinyl)-3-phosphoshikimate	Pentafunctional AROM polypeptide	Synthesis; Dehydration and isomerisation; Oxidation; Phosphorylation; Transfer of a carboxyvinyl group	RHEA	34755880
MMDBr0014091	Adenosine triphosphate	diphosphate	Nicotinamide-nucleotide adenylyltransferase	Synthesis	RHEA	34755880
MMDBr0014102	NAD	Dihydroxyacetone phosphate	Glycerol-1-phosphate dehydrogenase [NAD(P)+]	Dehydrogenation	RHEA	34755880
MMDBr0014103	NADP(+)	Dihydroxyacetone phosphate	Glycerol-1-phosphate dehydrogenase [NAD(P)+]	Dehydrogenation	RHEA	34755880
MMDBr0014114	N-(5-Phospho-D-ribosyl)anthranilate	1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate	Phosphoribosyl isomerase A	Isomerization	RHEA	34755880
MMDBr0014117	N-Acetyl-L-glutamate 5-semialdehyde	Hydrogen Ion	Protein ARG5,6, mitochondrial	Reduction	RHEA	34755880
MMDBr0014167	(R)-2,3-Dihydroxy-isovalerate	(2S)-2-acetolactic acid	Ketol-acid reductoisomerase, mitochondrial	Isomerization	RHEA	34755880
MMDBr0014251	(6R)-5,10-methylene-5,6,7,8-tetrahydrofolic acid	5,10-Methenyltetrahydrofolate	C-1-tetrahydrofolate synthase, cytoplasmic	Synthesis	RHEA	34755880
MMDBr0014299	Acetic acid	Acetyl-CoA	Acetyl-coenzyme A synthetase 1	Ligation; Synthesis	RHEA	34755880
MMDBr0014311	Isopentenyl pyrophosphate	Dimethylallylpyrophosphate	Isopentenyl-diphosphate Delta-isomerase	Isomerization	RHEA	34755880
MMDBr0014327	(2E,6E,10E)-geranylgeranyl diphosphate	diphosphate	Geranylgeranylglyceryl phosphate synthase	Synthesis	RHEA	34755880
MMDBr0014367	Adenine	Hypoxanthine	Adenine deaminase	Deamination	RHEA	34755880
MMDBr0014369	5,10-Methenyltetrahydrofolate	(6S)-10-formyltetrahydrofolic acid	C-1-tetrahydrofolate synthase, cytoplasmic	Reversible cyclization	RHEA	34755880
MMDBr0014407	Argininosuccinic acid	fumarate	Bifunctional protein ArgHA	Non-hydrolytic bond cleavage (or its reversal)	RHEA	34755880
MMDBr0014447	Adenosine triphosphate	ADP	UMP-CMP kinase	Phosphorylation	RHEA	34755880
MMDBr0014449	Deoxyadenosine	Inosine	Adenosine deaminase	Deamination; Phosphorylation	RHEA	34755880
MMDBr0014450	Deoxyadenosine	Inosine	Adenosine deaminase	Deamination; Phosphorylation	RHEA	34755880
MMDBr0014461	diphosphate	Hydrogen Ion	Inorganic pyrophosphatase	Dephosphorylation	RHEA	34755880
MMDBr0014474	5,6,7,8-Tetrahydromethanopterin	5,10-Methylenetetrahydromethanopterin	5,6,7,8-tetrahydromethanopterin hydro-lyase	Non-hydrolytic bond cleavage (or its reversal)	RHEA	34755880
MMDBr0014486	(R)-2,3-Dihydroxy-isovalerate	alpha-Ketoisovaleric acid	Dihydroxy-acid dehydratase, mitochondrial	Hydration/dehydration of C-O bond	RHEA	34755880
MMDBr0014487	(R)-2,3-Dihydroxy-isovalerate	alpha-Ketoisovaleric acid	Dihydroxy-acid dehydratase, mitochondrial	Hydration/dehydration of C-O bond	RHEA	34755880
MMDBr0014491	AICAR	Phosphoribosyl formamidocarboxamide	5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase	Synthesis	RHEA	34755880
MMDBr0014505	Hydrogen Ion	Ammonium	5'-deoxyadenosine deaminase	Deamination	RHEA	34755880
MMDBr0014506	Hydrogen Ion	Ammonium	5'-deoxyadenosine deaminase	Deamination	RHEA	34755880
MMDBr0014514	Adenosine triphosphate	ADP	Cytidylate kinase	Phosphorylation	RHEA	34755880
MMDBr0014522	D-Ribulose 5-phosphate	D-arabino-hex-3-ulose 6-phosphate	Bifunctional enzyme Fae/Hps	Synthesis	RHEA	34755880
MMDBr0014556	diphosphate	Phosphoribosyl pyrophosphate	Hypoxanthine-guanine phosphoribosyltransferase	Transfer of a ribosyl group	RHEA	34755880
MMDBr0014574	2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate	CDP-2,3-bis-O-(geranylgeranyl)-sn-glycerol	CDP-archaeol synthase	Synthesis	RHEA	34755880
MMDBr0014591	Guanosine triphosphate	7,8-dihydroneopterin 2',3'-cyclic phosphate	GTP cyclohydrolase MptA	Hydrolysis	RHEA	34755880
MMDBr0014601	2-amino-2,3,7-trideoxy-D-lyxo-hept-6-ulosonate	3-Dehydroquinate	3-dehydroquinate synthase	Synthesis	RHEA	34755880
MMDBr0017926	Adenosine triphosphate	ADP	CTP synthase	Synthesis	RHEA	34755880
MMDBr0014649	Hydrogen Ion	3-Sulfo-L-alanine	Cysteate synthase	Synthesis	RHEA	34755880
MMDBr0014718	(R)-2,3-Dihydroxy-3-methylpentanoate	2-Keto-3-methyl-valerate	Dihydroxy-acid dehydratase, mitochondrial	Hydration/dehydration of C-O bond	RHEA	34755880
MMDBr0014719	(R)-2,3-Dihydroxy-3-methylpentanoate	2-Keto-3-methyl-valerate	Dihydroxy-acid dehydratase, mitochondrial	Hydration/dehydration of C-O bond	RHEA	34755880
MMDBr0014763	7-Deaza-7-carboxyguanine	7-Cyano-7-carbaguanine	7-cyano-7-deazaguanine synthase	Synthesis	RHEA	34755880
MMDBr0014783	di-trans,octa-cis-undecaprenyl diphosphate	di-trans,octa-cis-undecaprenyl phosphate	Undecaprenyl-diphosphatase BcrC	Dephosphorylation	RHEA	34755880
MMDBr0017950	aldehydo-D-ribose 5-phosphate	Hydrogen Ion	Pyridoxal 5'-phosphate synthase subunit PDX1	Synthesis	RHEA	34755880
MMDBr0015316	L-Aspartate-semialdehyde	(2S,4S)-4-Hydroxy-2,3,4,5-tetrahydrodipicolinate	4-hydroxy-tetrahydrodipicolinate synthase	Synthesis	RHEA	34755880
MMDBr0015547	Adenosine monophosphate	Adenine	AMP phosphorylase 1	Phosphorylation	RHEA	34755880
MMDBr0015548	CMP	Ribose 1,5-bisphosphate	AMP phosphorylase 1	Phosphorylation	RHEA	34755880
MMDBr0015549	Phosphate	Ribose 1,5-bisphosphate	AMP phosphorylase 1	Phosphorylation	RHEA	34755880
MMDBr0015878	5'-Deoxyadenosine	5'-deoxyinosine	5'-deoxyadenosine deaminase	Deamination	RHEA	34755880
MMDBr0015879	5'-Deoxyadenosine	5'-deoxyinosine	5'-deoxyadenosine deaminase	Deamination	RHEA	34755880
MMDBr0017988	5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil	5'-Deoxyadenosine	7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase	Synthesis	RHEA	34755880
MMDBr0016807	Glycine	ADP-5-ethyl-4-methylthiazole-2-carboxylate	Thiamine thiazole synthase	Synthesis	RHEA	34755880
MMDBr0016907	Adenosine triphosphate	ADP	ATP synthase subunit alpha	ATP hydrolysis; Synthesis	RHEA	34755880
MMDBr0017101	3'-dephospho-CoA	CoA	GTP-dependent dephospho-CoA kinase	Phosphorylation	RHEA	34755880
MMDBr0017356	(2S)-2-phospholactic acid	(2S)-lactyl-2-diphospho-5'-guanosine	2-phospho-L-lactate guanylyltransferase	Transfer of a GMP	RHEA	34755880
MMDBr0017843	Adenosine triphosphate	Adenosine monophosphate	GMP synthase [glutamine-hydrolyzing]	Synthesis	RHEA	34755880
MMDBr0017863	Hydrogen Ion	Carbon dioxide	Probable L-tyrosine/L-aspartate decarboxylase	Carboxylation	RHEA	34755880
MMDBr0017871	(6R)-5,10-methylene-5,6,7,8-tetrahydrofolic acid	(6S)-5,6,7,8-tetrahydrofolic acid	Serine hydroxymethyltransferase	Methylation	RHEA	34755880
MMDBr0017874	Water	L-Glutamic acid	Thermolabile glutaminase	Synthesis	RHEA	34755880
MMDBr0017879	Adenosine triphosphate	2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine	Phosphoribosylformylglycinamidine synthase	Synthesis	RHEA	34755880
MMDBr0017882	Adenosine triphosphate	ADP	Carbamoyl-phosphate synthase small chain	Synthesis	RHEA	34755880
MMDBr0017897	Adenosine triphosphate	diphosphate	S-adenosylmethionine synthase	Synthesis	RHEA	34755880
MMDBr0024360	Adenosine triphosphate	diphosphate	Valine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024368	Adenosine triphosphate	diphosphate	Isoleucine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024389	Adenosine triphosphate	diphosphate	Leucine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024411	Adenosine triphosphate	Hydrogen Ion	Type-2 serine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024415	(S)-4-Amino-5-oxopentanoate	Hydrogen Ion	Glutamyl-tRNA reductase	Reduction	RHEA	34755880
MMDBr0024418	Adenosine triphosphate	diphosphate	Alanine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024424	S-Adenosylmethionine	S-Adenosylhomocysteine	Protein-L-isoaspartate O-methyltransferase	Methylation	RHEA	34755880
MMDBr0024449	Adenosine triphosphate	diphosphate	Methionine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024474	Adenosine triphosphate	diphosphate	Proline--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024483	Water	Hydrogen Ion	Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C	Amide group addition	RHEA	34755880
MMDBr0024522	Adenosine triphosphate	diphosphate	Glycine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024568	Water	Hydrogen Ion	Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C	Amide group addition	RHEA	34755880
MMDBr0024628	Adenosine triphosphate	Hydrogen Ion	Phenylalanine--tRNA ligase beta subunit	Ligation	RHEA	34755880
MMDBr0024656	Adenosine triphosphate	diphosphate	Arginine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024745	L-Glutamic acid	diphosphate	Glutamate--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024759	Adenosine triphosphate	diphosphate	RNA 3'-terminal phosphate cyclase	Cycle formation	RHEA	34755880
MMDBr0024787	Adenosine triphosphate	Hydrogen Ion	Threonine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024797	Adenosine triphosphate	diphosphate	O-phosphoserine--tRNA(Cys) ligase	Ligation	RHEA	34755880
MMDBr0024798	Hydrogen Ion	Phosphate	O-phospho-L-seryl-tRNA:Cys-tRNA synthase	Synthesis	RHEA	34755880
MMDBr0024950	Tetra-mu3-sulfido-tetrairon(2+)	Hydrogen Ion	Digeranylgeranylglycerophospholipid reductase	Reduction	RHEA	34755880
MMDBr0024951	Hydrogen Ion	Tetra-mu3-sulfido-tetrairon(2+)	Digeranylgeranylglycerophospholipid reductase	Reduction	RHEA	34755880
MMDBr0024956	S-Adenosylmethionine	Hydrogen Ion	Diphthine synthase	Synthesis	RHEA	34755880
MMDBr0024971	L-Threonylcarbamoyladenylate	Hydrogen Ion	tRNA N6-adenosine threonylcarbamoyltransferase	Synthesis	RHEA	34755880
MMDBr0025060	Adenosine triphosphate	Hydrogen Ion	Type-2 serine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0025075	S-Adenosylmethionine	Hydrogen Ion	Ribosomal RNA large subunit methyltransferase E	Methylation	RHEA	34755880
MMDBr0025085	S-Adenosylmethionine	Hydrogen Ion	Putative ribosomal RNA large subunit methyltransferase H	Methylation	RHEA	34755880
MMDBr0025114	S-Adenosylmethionine	Hydrogen Ion	tRNA (cytidine(56)-2'-O)-methyltransferase	Methylation	RHEA	34755880
MMDBr0025242	S-Adenosylmethionine	Hydrogen Ion	Ribosomal RNA small subunit methyltransferase Nep1	Methylation	RHEA	34755880
MMDBr0025501	Tetra-mu3-sulfido-tetrairon(2+)	Hydrogen Ion	Digeranylgeranylglycerophospholipid reductase	Reduction	RHEA	34755880
MMDBr0025502	Hydrogen Ion	Tetra-mu3-sulfido-tetrairon(2+)	Digeranylgeranylglycerophospholipid reductase	Reduction	RHEA	34755880
MMDBr0025563	S-Adenosylmethionine	Hydrogen Ion	tRNA (pseudouridine(54)-N(1))-methyltransferase	Methylation	RHEA	34755880
MMDBr0026022	Adenosine monophosphate	Adenosine	5'-nucleotidase SurE	Hydrolysis of nucleotide; Dephosphorylation	RHEA	34755880
MMDBr0026023	Cytidine monophosphate	Adenosine	5'-nucleotidase SurE	Hydrolysis of nucleotide; Dephosphorylation	RHEA	34755880
MMDBr0026024	Uridine 5'-monophosphate	Uridine	5'-nucleotidase SurE	Hydrolysis of nucleotide; Dephosphorylation	RHEA	34755880
MMDBr0026025	Guanosine monophosphate	Guanosine	5'-nucleotidase SurE	Hydrolysis of nucleotide; Dephosphorylation	RHEA	34755880

Genome Data

Genome Link

Not Available

Genome Length

Not Available

# Predicted Proteins

GenBank Sequence Modification Date

17-FEB-2022

MiMeDB Deposition Date

Reference

PMID: 17704766

Source Links

GenBank