MiMeDB: Rickettsia africae ESF-5 (MMDBm0002470)

Microbe Identification

Microbe name

Rickettsia africae ESF-5

NCBI Taxonomy ID

347255

Microbe Taxonomy

Superkingdom

Bacteria

Kingdom

Eubacteria

Phylum

Proteobacteria

Class

Alphaproteobacteria

Order

Rickettsiales

Family

Rickettsiaceae

Genus

Rickettsia

Species

africae

Strain

Microbe Properties

Gram staining properties

Positive

Shape

Bacilli

Mobility

Flagellar presence

Number of membranes

Oxygen preference

Aerobe

Optimal temperature

Not Available

Temperature range

Mesophilic

Habitat

HostAssociated

Biotic relationship

Symbiotic

Cell arrangement

Not Available

Sporulation

Nonsporulating

Metabolism

Not Available

Energy source

Not Available

Host and Biospecimens

Host	Body site	Biospecimen	Details	Data Source	Reference
Human			Unknown

Health Effects

Host	Related Health Condition	Biospecimen	Microbal response/effect	Data Source	Reference

Related Metabolites

Metabolic Reactions

Reactions

Reaction ID	Precursor	Product	Enzyme	Reaction Type	Data Source	Reference
MMDBr0012876	Deoxyuridine triphosphate	diphosphate	Probable deoxyuridine 5'-triphosphate nucleotidohydrolase	Dephosphorylation; Hydrolysis of bond	RHEA	34755880
MMDBr0012975	NAD	Dihydroxyacetone phosphate	Glycerol-3-phosphate dehydrogenase [NAD(+)]	Dehydrogenation	RHEA	34755880
MMDBr0012976	NADP(+)	Dihydroxyacetone phosphate	Glycerol-3-phosphate dehydrogenase [NAD(P)+]	Dehydrogenation	RHEA	34755880
MMDBr0012989	Adenosine triphosphate	ADP	D-alanine--D-alanine ligase	Ligation	RHEA	34755880
MMDBr0013027	Adenosine triphosphate	ADP	Cytidylate kinase	Phosphorylation	RHEA	34755880
MMDBr0013170	Adenosine monophosphate	ADP	Adenylate kinase	Phosphorylation	RHEA	34755880
MMDBr0013179	Adenosine triphosphate	ADP	Replicase large subunit	Synthesis of a primer	RHEA	34755880
MMDBr0013194	Water	Hydroxymethylbilane	Porphobilinogen deaminase	Deamination	RHEA	34755880
MMDBr0013212	7-Aminomethyl-7-carbaguanine	7-Cyano-7-carbaguanine	NADPH-dependent 7-cyano-7-deazaguanine reductase	Reduction	RHEA	34755880
MMDBr0013226	Adenosine triphosphate	ADP	Putative thymidylate kinase	Phosphorylation	RHEA	34755880
MMDBr0013280	D-Arabinose 5-phosphate	3-deoxy-alpha-D-manno-2-octulosonate-8-phosphate	2-dehydro-3-deoxyphosphooctonate aldolase	Aldol addition (or reverse)	RHEA	34755880
MMDBr0013422	LL-2,6-Diaminoheptanedioate	Meso-2,6-Diaminoheptanedioate	Diaminopimelate epimerase	Epimerization; Racemization	RHEA	34755880
MMDBr0013575	Acetyl-CoA	Citric acid	Citrate (Re)-synthase	Synthesis	RHEA	34755880
MMDBr0013659	Guanosine triphosphate	7,8-dihydroneopterin 3'-triphosphate	Bifunctional protein FolKE	Hydrolysis	RHEA	34755880
MMDBr0013674	Adenosine triphosphate	ADP	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial	Ligation	RHEA	34755880
MMDBr0013745	Coproporphyrinogen III	Carbon dioxide	Oxygen-dependent coproporphyrinogen-III oxidase	Oxidation	RHEA	34755880
MMDBr0013792	Adenosine triphosphate	ADP	NAD kinase	Phosphorylation	RHEA	34755880
MMDBr0013801	Phosphoenolpyruvic acid	Phosphate	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	Synthesis	RHEA	34755880
MMDBr0013908	Guanosine triphosphate	Guanosine diphosphate	GTPase ArgK	Dephosphorylation; Hydrolysis; Nucleic acid synthesis and/or repair	RHEA	34755880
MMDBr0013929	Hydrogen Ion	Carbon dioxide	Uroporphyrinogen decarboxylase	Decarboxylation	RHEA	34755880
MMDBr0013970	L-Alanine	D-Alanine	L-alanine/L-glutamate racemase	Racemization	RHEA	34755880
MMDBr0014105	(S)-malate(2-)	Hydrogen Ion	Malate dehydrogenase	Dehydrogenation	RHEA	34755880
MMDBr0014225	Water	LL-2,6-Diaminoheptanedioate	Succinyl-diaminopimelate desuccinylase	Hydrolysis of carbon-nitrogen bond	RHEA	34755880
MMDBr0014229	5-Amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate	(2S)-2-[5-Amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinic acid	Phosphoribosylaminoimidazole-succinocarboxamide synthase	Synthesis	RHEA	34755880
MMDBr0014236	dCTP	Deoxyuridine triphosphate	dCTP deaminase	Deamination	RHEA	34755880
MMDBr0014251	(6R)-5,10-methylene-5,6,7,8-tetrahydrofolic acid	5,10-Methenyltetrahydrofolate	C-1-tetrahydrofolate synthase, cytoplasmic	Synthesis	RHEA	34755880
MMDBr0014311	Isopentenyl pyrophosphate	Dimethylallylpyrophosphate	Isopentenyl-diphosphate Delta-isomerase	Isomerization	RHEA	34755880
MMDBr0014323	Adenosine triphosphate	ADP	Bifunctional enzyme MurC/Ddl	Ligation	RHEA	34755880
MMDBr0014337	3-deoxy-D-manno-2-octulosonate	CMP-3-deoxy-beta-D-manno-octulosonate	3-deoxy-manno-octulosonate cytidylyltransferase	Transfer of a cytidylyl group	RHEA	34755880
MMDBr0014369	5,10-Methenyltetrahydrofolate	(6S)-10-formyltetrahydrofolic acid	C-1-tetrahydrofolate synthase, cytoplasmic	Reversible cyclization	RHEA	34755880
MMDBr0014514	Adenosine triphosphate	ADP	Cytidylate kinase	Phosphorylation	RHEA	34755880
MMDBr0014763	7-Deaza-7-carboxyguanine	7-Cyano-7-carbaguanine	7-cyano-7-deazaguanine synthase	Synthesis	RHEA	34755880
MMDBr0014776	Farnesyl pyrophosphate	diphosphate	Protoheme IX farnesyltransferase, mitochondrial	Farnesylation	RHEA	34755880
MMDBr0014825	di-trans,octa-cis-undecaprenyl phosphate	di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine	Phospho-N-acetylmuramoyl-pentapeptide-transferase	Transfer of phospho-N-acetylmuramoyl-pentapeptide	RHEA	34755880
MMDBr0015026	di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine	di-trans-octa-cis-undecaprenyl diphospho-[N-acetyl-alpha-D-glucosaminyl-(1->4)]-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine	UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase	UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase 1; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase 2; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase 3	RHEA	34755880
MMDBr0015316	L-Aspartate-semialdehyde	(2S,4S)-4-Hydroxy-2,3,4,5-tetrahydrodipicolinate	4-hydroxy-tetrahydrodipicolinate synthase	Synthesis	RHEA	34755880
MMDBr0015402	(S)-2,3,4,5-tetrahydrodipicolinate	(2S,4S)-4-Hydroxy-2,3,4,5-tetrahydrodipicolinate	4-hydroxy-tetrahydrodipicolinate reductase	Reduction	RHEA	34755880
MMDBr0015405	(S)-2,3,4,5-tetrahydrodipicolinate	(2S,4S)-4-Hydroxy-2,3,4,5-tetrahydrodipicolinate	4-hydroxy-tetrahydrodipicolinate reductase	Reduction	RHEA	34755880
MMDBr0016907	Adenosine triphosphate	ADP	ATP synthase subunit alpha	ATP hydrolysis; Synthesis	RHEA	34755880
MMDBr0017871	(6R)-5,10-methylene-5,6,7,8-tetrahydrofolic acid	(6S)-5,6,7,8-tetrahydrofolic acid	Serine hydroxymethyltransferase	Methylation	RHEA	34755880
MMDBr0024345	Adenosine triphosphate	Hydrogen Ion	Tyrosine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024360	Adenosine triphosphate	diphosphate	Valine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024368	Adenosine triphosphate	diphosphate	Isoleucine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024389	Adenosine triphosphate	diphosphate	Leucine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024401	L-Serine	Hydrogen Ion	Holo-[acyl-carrier-protein] synthase	Dehydrogenation; Synthesis	RHEA	34755880
MMDBr0024411	Adenosine triphosphate	Hydrogen Ion	Type-2 serine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024474	Adenosine triphosphate	diphosphate	Proline--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024483	Water	Hydrogen Ion	Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C	Amide group addition	RHEA	34755880
MMDBr0024522	Adenosine triphosphate	diphosphate	Glycine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024539	Hydrogen Ion	5'-Deoxyadenosine	Lipoyl synthase	Synthesis	RHEA	34755880
MMDBr0024559	Adenosine triphosphate	Hydrogen Ion	Histidine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024568	Water	Hydrogen Ion	Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C	Amide group addition	RHEA	34755880
MMDBr0024578	Adenosine triphosphate	diphosphate	Cysteine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024590	Adenosine triphosphate	ADP	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0024597	L-Aspartic acid	diphosphate	Aspartate--tRNA(Asp/Asn) ligase	Ligation	RHEA	34755880
MMDBr0024628	Adenosine triphosphate	Hydrogen Ion	Phenylalanine--tRNA ligase beta subunit	Ligation	RHEA	34755880
MMDBr0024630	S-Adenosylmethionine	Hydrogen Ion	Ribosomal RNA small subunit methyltransferase A	Methylation	RHEA	34755880
MMDBr0024656	Adenosine triphosphate	diphosphate	Arginine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024666	Adenosine triphosphate	diphosphate	Lysine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024765	7-Aminomethyl-7-carbaguanine	Guanine	Putative queuine tRNA-ribosyltransferase	Transfer of a ribosyl group	RHEA	34755880
MMDBr0024778	(6S)-10-formyltetrahydrofolic acid	Hydrogen Ion	Methionyl-tRNA formyltransferase	Transfer of a formyl group	RHEA	34755880
MMDBr0024787	Adenosine triphosphate	Hydrogen Ion	Threonine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024834	S-Adenosylmethionine	Hydrogen Ion	Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE	Methylation	RHEA	34755880
MMDBr0024883	S-Adenosylmethionine	Hydrogen Ion	S-adenosylmethionine:tRNA ribosyltransferase-isomerase	Isomerization	RHEA	34755880
MMDBr0024967	S-Adenosylmethionine	Hydrogen Ion	tRNA (guanine(37)-N1)-methyltransferase Trm5b	Methylation	RHEA	34755880
MMDBr0024971	L-Threonylcarbamoyladenylate	Hydrogen Ion	tRNA N6-adenosine threonylcarbamoyltransferase	Synthesis	RHEA	34755880
MMDBr0025060	Adenosine triphosphate	Hydrogen Ion	Type-2 serine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0025066	S-Adenosylmethionine	Hydrogen Ion	Demethylmenaquinone methyltransferase	Methylation	RHEA	34755880
MMDBr0025075	S-Adenosylmethionine	Hydrogen Ion	Ribosomal RNA large subunit methyltransferase E	Methylation	RHEA	34755880
MMDBr0025078	S-Adenosylmethionine	S-Adenosylhomocysteine	Ribosomal RNA small subunit methyltransferase G	Methylation	RHEA	34755880
MMDBr0025105	S-Adenosylmethionine	Hydrogen Ion	Ribosomal RNA small subunit methyltransferase H	Methylation	RHEA	34755880
MMDBr0025163	ADP	Hydrogen Ion	Putative pyruvate, phosphate dikinase regulatory protein 1	Phosphorylation	RHEA	34755880
MMDBr0025164	Hydrogen Ion	diphosphate	Putative pyruvate, phosphate dikinase regulatory protein 1	Phosphorylation	RHEA	34755880
MMDBr0025167	Adenosine triphosphate	Hydrogen Ion	tRNA(Ile)-lysidine synthase	Synthesis	RHEA	34755880
MMDBr0025193	Adenosine triphosphate	ADP	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0025258	Adenosine triphosphate	Hydrogen Ion	tRNA-specific 2-thiouridylase MnmA	2-Thiolation of uridine	RHEA	34755880
MMDBr0025620	L-Cysteine	Hydrogen Ion	Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase	Transfer of the diacylglyceryl group	RHEA	34755880
MMDBr0025650	Hydrogen Ion	Hydrogen Ion	NADH-quinone oxidoreductase subunit C/D	Redox reaction	RHEA	34755880
MMDBr0025806	Water	Fe(II)-heme a	Heme A synthase	Synthesis	RHEA	34755880
MMDBr0025807	Water	Fe(II)-heme a	Heme A synthase	Synthesis	RHEA	34755880
MMDBr0026014	Phosphate	Uridine 5'-diphosphate	Ribonuclease PH	RNA degradation	RHEA	34755880
MMDBr0026015	Phosphate	Uridine 5'-diphosphate	Ribonuclease PH	RNA degradation	RHEA	34755880
MMDBr0026016	Phosphate	Guanosine 3',5'-bis(diphosphate)	Ribonuclease PH	RNA degradation	RHEA	34755880
MMDBr0026017	Phosphate	Adenosine diphosphate	Ribonuclease PH	RNA degradation	RHEA	34755880
MMDBr0026046	Uridine 5'-diphosphate	Uridine triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026047	Uridine 5'-diphosphate	Cytidine triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026048	Guanosine 3',5'-bis(diphosphate)	Guanosine triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026065	Cytidine triphosphate	Cytidine monophosphate	Nucleoside triphosphate pyrophosphatase	Purine metabolism and pyrimidine metabolism; Hydrolysis of pyrophosphate; Dephosphorylation	RHEA	34755880
MMDBr0026066	Uridine triphosphate	Uridine 5'-monophosphate	Nucleoside triphosphate pyrophosphatase	Purine metabolism and pyrimidine metabolism; Hydrolysis of pyrophosphate; Dephosphorylation	RHEA	34755880
MMDBr0026067	Adenosine triphosphate	Adenosine monophosphate	Nucleoside triphosphate pyrophosphatase	Purine metabolism and pyrimidine metabolism; Hydrolysis of pyrophosphate; Dephosphorylation	RHEA	34755880
MMDBr0026068	Guanosine triphosphate	Guanosine monophosphate	Nucleoside triphosphate pyrophosphatase	Purine metabolism and pyrimidine metabolism; Hydrolysis of pyrophosphate; Dephosphorylation	RHEA	34755880
MMDBr0026085	Deoxyuridine-5'-diphosphate	Deoxyuridine triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026086	2'-Deoxycytidine 5'-diphosphate	Deoxycytidine 5'-triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026087	2'-Deoxyadenosine 5'-diphosphate	Deoxyadenosine triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026088	2'-Deoxyguanosine 5'-diphosphate	2'-Deoxyguanosine 5'-triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026089	Deoxyuridine triphosphate	2'-Deoxyuridine 5'-phosphate	Nucleoside triphosphate pyrophosphatase	Purine metabolism and pyrimidine metabolism; Hydrolysis of pyrophosphate; Dephosphorylation	RHEA	34755880
MMDBr0026090	Deoxycytidine 5'-triphosphate	2'-Deoxycytidine 5'-phosphate	Nucleoside triphosphate pyrophosphatase	Purine metabolism and pyrimidine metabolism; Hydrolysis of pyrophosphate; Dephosphorylation	RHEA	34755880
MMDBr0026091	Deoxyadenosine triphosphate	Deoxyadenosine monophosphate	Nucleoside triphosphate pyrophosphatase	Purine metabolism and pyrimidine metabolism; Hydrolysis of pyrophosphate; Dephosphorylation	RHEA	34755880
MMDBr0026092	2'-Deoxyguanosine 5'-triphosphate	2'-Deoxyguanosine 5'-monophosphate	Nucleoside triphosphate pyrophosphatase	Purine metabolism and pyrimidine metabolism; Hydrolysis of pyrophosphate; Dephosphorylation	RHEA	34755880

Genome Data

Genome Link

Not Available

Genome Length

Not Available

# Predicted Proteins

GenBank Sequence Modification Date

17-FEB-2022

MiMeDB Deposition Date

Reference

PMID: 17704766

Source Links

GenBank