MiMeDB: Methylobacterium extorquens PA1 (MMDBm0001856)

Microbe Identification

Microbe name

Methylobacterium extorquens PA1

NCBI Taxonomy ID

419610

Microbe Taxonomy

Superkingdom

Bacteria

Kingdom

Eubacteria

Phylum

Proteobacteria

Class

Alphaproteobacteria

Order

Rhizobiales

Family

Methylobacteriaceae

Genus

Methylobacterium

Species

extorquens

Strain

Microbe Properties

Gram staining properties

Positive

Shape

Bacilli

Mobility

Yes

Flagellar presence

Yes

Number of membranes

Oxygen preference

Facultative aerobe

Optimal temperature

Temperature range

Mesophilic

Habitat

Multiple

Biotic relationship

Free living

Cell arrangement

Pairs - Singles

Sporulation

Pairs - Singles

Metabolism

Not Available

Energy source

Methylotroph

Host and Biospecimens

Host	Body site	Biospecimen	Details	Data Source	Reference
Human	Gut	Feces	Expected but not quantified

Health Effects

Host	Related Health Condition	Biospecimen	Microbal response/effect	Data Source	Reference

Related Metabolites

Metabolic Reactions

Reactions

Reaction ID	Precursor	Product	Enzyme	Reaction Type	Data Source	Reference
MMDBr0012860	(2R)-2-phosphoglyceric acid	Water	Enolase	Enolization	RHEA	34755880
MMDBr0012895	diphosphate	Phosphoribosyl pyrophosphate	Orotate phosphoribosyltransferase	Transfer of a ribosyl group	RHEA	34755880
MMDBr0012970	D-erythro-1-(Imidazol-4-yl)glycerol 3-phosphate	3-(Imidazol-4-yl)-2-oxopropyl phosphate	Imidazoleglycerol-phosphate dehydratase	Hydration/dehydration of C-O bond; Synthesis	RHEA	34755880
MMDBr0012971	beta-D-Fructose 1,6-bisphosphate	beta-D-Fructose 6-phosphate	Fructose-1,6-bisphosphatase/inositol-1-monophosphatase	Aldol addition (or reverse); Dephosphorylation	RHEA	34755880
MMDBr0012989	Adenosine triphosphate	ADP	D-alanine--D-alanine ligase	Ligation	RHEA	34755880
MMDBr0013026	Hydrogen Ion	Carbon dioxide	Orotidine 5'-phosphate decarboxylase	Decarboxylation	RHEA	34755880
MMDBr0013038	diphosphate	Phosphoribosyl pyrophosphate	Tryptophan biosynthesis protein TrpCD	Transfer of a ribosyl group	RHEA	34755880
MMDBr0013046	(6R)-5,10-methylene-5,6,7,8-tetrahydrofolic acid	(6S)-5,6,7,8-tetrahydrofolic acid	3-methyl-2-oxobutanoate hydroxymethyltransferase	Methylation	RHEA	34755880
MMDBr0013098	NADP(+)	Hydrogen Ion	UDP-N-acetylenolpyruvoylglucosamine reductase	Reduction	RHEA	34755880
MMDBr0013170	Adenosine monophosphate	ADP	Adenylate kinase	Phosphorylation	RHEA	34755880
MMDBr0013179	Adenosine triphosphate	ADP	Replicase large subunit	Synthesis of a primer	RHEA	34755880
MMDBr0013212	7-Aminomethyl-7-carbaguanine	7-Cyano-7-carbaguanine	NADPH-dependent 7-cyano-7-deazaguanine reductase	Reduction	RHEA	34755880
MMDBr0013221	(R)-2,3-Dihydroxy-3-methylpentanoate	(S)-2-ethyl-2-hydroxy-3-oxobutanoic acid	Ketol-acid reductoisomerase, mitochondrial	Isomerization	RHEA	34755880
MMDBr0013251	Water	Hydrogen Ion	Sulfite reductase [NADPH] hemoprotein beta-component	Reduction	RHEA	34755880
MMDBr0013339	aldehydo-D-ribose 5-phosphate	D-Ribulose 5-phosphate	Bifunctional ribokinase/ribose-5-phosphate isomerase A	Isomerization	RHEA	34755880
MMDBr0013357	(2R)-3-phosphoglyceric acid	(2R)-3-phospho-glyceroyl phosphate	Phosphoglycerate kinase	Phosphorylation	RHEA	34755880
MMDBr0013422	LL-2,6-Diaminoheptanedioate	Meso-2,6-Diaminoheptanedioate	Diaminopimelate epimerase	Epimerization; Racemization	RHEA	34755880
MMDBr0013451	Carbamate	Carbon dioxide	Putative aminoacrylate hydrolase RutD	Hydrolysis of bond	RHEA	34755880
MMDBr0013470	(2R)-2-phosphoglyceric acid	(2R)-3-phosphoglyceric acid	2,3-bisphosphoglycerate-independent phosphoglycerate mutase	Intramolecular transfer of functional group	RHEA	34755880
MMDBr0013549	Adenosine monophosphate	Phosphoribosyl pyrophosphate	Adenine phosphoribosyltransferase	Transfer of a ribosyl group	RHEA	34755880
MMDBr0013642	(S)-2,3,4,5-tetrahydrodipicolinate	(S)-2-succinylamino-6-oxoheptanedioic acid	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	Transfer of succinyl moiety	RHEA	34755880
MMDBr0013729	Adenosine triphosphate	Adenosine phosphosulfate	Sulfate adenylyltransferase subunit 2	Reversible transfer of an adenylyl group	RHEA	34755880
MMDBr0013768	4-(Cytidine 5'-diphospho)-2-C-methyl-D-erythritol	2-Phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase	Phosphorylation	RHEA	34755880
MMDBr0013790	Adenosine triphosphate	ADP	Phosphoenolpyruvate carboxykinase (ATP)	Phosphorylation	RHEA	34755880
MMDBr0013801	Phosphoenolpyruvic acid	Phosphate	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	Synthesis	RHEA	34755880
MMDBr0013809	Ribose-1-phosphate	D-Ribose-5-phosphate	Phosphopentomutase	Transfers of a phosphate group; Isomerization; Intramolecular transfer of functional group	RHEA	34755880
MMDBr0013895	L-Glutamic-gamma-semialdehyde	Hydrogen Ion	Gamma-glutamyl phosphate reductase	Reduction	RHEA	34755880
MMDBr0013946	Carbamoylphosphate	Hydrogen Ion	Protein pyrABCN	Transfer of a carbamoyl group	RHEA	34755880
MMDBr0013966	(6S)-5,6,7,8-tetrahydrofolic acid	(6S)-10-formyltetrahydrofolic acid	C-1-tetrahydrofolate synthase, cytoplasmic	Ligation; Synthesis	RHEA	34755880
MMDBr0014061	5-O-(1-Carboxyvinyl)-3-phosphoshikimate	Chorismate	Chorismate synthase	Synthesis	RHEA	34755880
MMDBr0014105	(S)-malate(2-)	Hydrogen Ion	Malate dehydrogenase	Dehydrogenation	RHEA	34755880
MMDBr0014122	FMNH2	Flavin mononucleotide	NAD(P)H-dependent FMN reductase atnL	Reduction	RHEA	34755880
MMDBr0014126	Adenosine triphosphate	ADP	Glycerol kinase	Phosphorylation	RHEA	34755880
MMDBr0014135	Water	Deoxyadenosine	Adenosylhomocysteinase	Reversible hydrolysis	RHEA	34755880
MMDBr0014167	(R)-2,3-Dihydroxy-isovalerate	(2S)-2-acetolactic acid	Ketol-acid reductoisomerase, mitochondrial	Isomerization	RHEA	34755880
MMDBr0014225	Water	LL-2,6-Diaminoheptanedioate	Succinyl-diaminopimelate desuccinylase	Hydrolysis of carbon-nitrogen bond	RHEA	34755880
MMDBr0014257	Adenosine triphosphate	Nicotinic acid adenine dinucleotide	Probable nicotinate-nucleotide adenylyltransferase	Reversible transfer of an adenylyl group	RHEA	34755880
MMDBr0014299	Acetic acid	Acetyl-CoA	Acetyl-coenzyme A synthetase 1	Ligation; Synthesis	RHEA	34755880
MMDBr0014323	Adenosine triphosphate	ADP	Bifunctional enzyme MurC/Ddl	Ligation	RHEA	34755880
MMDBr0014333	alpha-D-Glucosamine 1-phosphate	D-glucosamine 6-phosphate	Phosphoglucosamine mutase	Intramolecular transfer of functional group	RHEA	34755880
MMDBr0014337	3-deoxy-D-manno-2-octulosonate	CMP-3-deoxy-beta-D-manno-octulosonate	3-deoxy-manno-octulosonate cytidylyltransferase	Transfer of a cytidylyl group	RHEA	34755880
MMDBr0014407	Argininosuccinic acid	fumarate	Bifunctional protein ArgHA	Non-hydrolytic bond cleavage (or its reversal)	RHEA	34755880
MMDBr0014619	L-3,4-Dihydroxybutan-2-one 4-phosphate	6,7-Dimethyl-8-(1-D-ribityl)lumazine	6,7-dimethyl-8-ribityllumazine synthase	Synthesis	RHEA	34755880
MMDBr0014763	7-Deaza-7-carboxyguanine	7-Cyano-7-carbaguanine	7-cyano-7-deazaguanine synthase	Synthesis	RHEA	34755880
MMDBr0015026	di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine	di-trans-octa-cis-undecaprenyl diphospho-[N-acetyl-alpha-D-glucosaminyl-(1->4)]-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine	UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase	UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase 1; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase 2; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase 3	RHEA	34755880
MMDBr0015055	FMNH2	(Z)-3-Ureidoacrylate	Pyrimidine monooxygenase RutA	Oxygenation	RHEA	34755880
MMDBr0015056	FMNH2	(Z)-2-methylureidoacrylic acid	Pyrimidine monooxygenase RutA	Oxygenation	RHEA	34755880
MMDBr0015057	(Z)-3-Ureidoacrylate	3-Aminoacrylate	Ureidoacrylate amidohydrolase RutB	Hydrolysis of bond	RHEA	34755880
MMDBr0015135	4-(phosphooxy)-L-threonine	3-Amino-2-oxopropyl phosphate	4-hydroxythreonine-4-phosphate dehydrogenase	Dehydrogenation	RHEA	34755880
MMDBr0015136	3-Isopropylmalate	2-Isopropylmalic acid	3-isopropylmalate dehydratase large subunit gloJ	Isomerization	RHEA	34755880
MMDBr0015384	3-Aminoacrylate	Malonic semialdehyde	Putative aminoacrylate peracid reductase RutC	Reduction	RHEA	34755880
MMDBr0015860	(Z)-2-methylureidoacrylic acid	(Z)-2-methylaminoacrylic acid	Ureidoacrylate amidohydrolase RutB	Hydrolysis of bond	RHEA	34755880
MMDBr0015861	(Z)-3-Ureidoacrylate	3-Aminoacrylate	Ureidoacrylate amidohydrolase RutB	Hydrolysis of bond	RHEA	34755880
MMDBr0016813	2-Aminobenzoic acid	2-(4-dimethylaminophenyl)diazenylbenzoic acid	FMN-dependent NADPH-azoreductase	Reduction	RHEA	34755880
MMDBr0016907	Adenosine triphosphate	ADP	ATP synthase subunit alpha	ATP hydrolysis; Synthesis	RHEA	34755880
MMDBr0017834	(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate	D-Glyceraldehyde 3-phosphate	Tryptophan synthase	Synthesis	RHEA	34755880
MMDBr0017871	(6R)-5,10-methylene-5,6,7,8-tetrahydrofolic acid	(6S)-5,6,7,8-tetrahydrofolic acid	Serine hydroxymethyltransferase	Methylation	RHEA	34755880
MMDBr0017874	Water	L-Glutamic acid	Thermolabile glutaminase	Synthesis	RHEA	34755880
MMDBr0017897	Adenosine triphosphate	diphosphate	S-adenosylmethionine synthase	Synthesis	RHEA	34755880
MMDBr0017916	5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide	AICAR	Imidazole glycerol phosphate synthase subunit HisH	Synthesis	RHEA	34755880
MMDBr0024401	L-Serine	Hydrogen Ion	Holo-[acyl-carrier-protein] synthase	Dehydrogenation; Synthesis	RHEA	34755880
MMDBr0024411	Adenosine triphosphate	Hydrogen Ion	Type-2 serine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024418	Adenosine triphosphate	diphosphate	Alanine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024424	S-Adenosylmethionine	S-Adenosylhomocysteine	Protein-L-isoaspartate O-methyltransferase	Methylation	RHEA	34755880
MMDBr0024474	Adenosine triphosphate	diphosphate	Proline--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024483	Water	Hydrogen Ion	Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C	Amide group addition	RHEA	34755880
MMDBr0024539	Hydrogen Ion	5'-Deoxyadenosine	Lipoyl synthase	Synthesis	RHEA	34755880
MMDBr0024546	Hydrogen Ion	(6S)-5,6,7,8-tetrahydrofolic acid	Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO	Methylation	RHEA	34755880
MMDBr0024568	Water	Hydrogen Ion	Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C	Amide group addition	RHEA	34755880
MMDBr0024590	Adenosine triphosphate	ADP	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0024656	Adenosine triphosphate	diphosphate	Arginine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024707	di-mu-Sulfido-diiron(1+)	5'-Deoxyadenosine	Biotin synthase	Synthesis	RHEA	34755880
MMDBr0024745	L-Glutamic acid	diphosphate	Glutamate--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024813	Dimethylallylpyrophosphate	diphosphate	tRNA dimethylallyltransferase	Transfer of a dimethylallyl group	RHEA	34755880
MMDBr0024826	2-deoxy-alpha-D-ribose 1-phosphate	Deoxyribose 5-phosphate	Phosphopentomutase	Transfers of a phosphate group; Isomerization; Intramolecular transfer of functional group	RHEA	34755880
MMDBr0024833	Tetra-mu3-sulfido-tetrairon(2+)	Water	Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein	Reduction	RHEA	34755880
MMDBr0024883	S-Adenosylmethionine	Hydrogen Ion	S-adenosylmethionine:tRNA ribosyltransferase-isomerase	Isomerization	RHEA	34755880
MMDBr0024925	Glycerol 3-phosphate	Phosphate	Glycerol-3-phosphate acyltransferase	Acylation	RHEA	34755880
MMDBr0024971	L-Threonylcarbamoyladenylate	Hydrogen Ion	tRNA N6-adenosine threonylcarbamoyltransferase	Synthesis	RHEA	34755880
MMDBr0024974	S-Adenosylmethionine	Hydrogen Ion	tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase	Synthesis	RHEA	34755880
MMDBr0024977	S-Adenosylmethionine	Hydrogen Ion	Ribosomal protein S12 methylthiotransferase RimO	Methylthiolation	RHEA	34755880
MMDBr0025050	Hydrogen Ion	Carbon dioxide	Putative 8-amino-7-oxononanoate synthase	Ligation; Synthesis	RHEA	34755880
MMDBr0025060	Adenosine triphosphate	Hydrogen Ion	Type-2 serine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0025078	S-Adenosylmethionine	S-Adenosylhomocysteine	Ribosomal RNA small subunit methyltransferase G	Methylation	RHEA	34755880
MMDBr0025085	S-Adenosylmethionine	Hydrogen Ion	Putative ribosomal RNA large subunit methyltransferase H	Methylation	RHEA	34755880
MMDBr0025102	di-mu-Sulfido-diiron(1+)	5'-Deoxyadenosine	Ribosomal RNA large subunit methyltransferase N	Methylation	RHEA	34755880
MMDBr0025105	S-Adenosylmethionine	Hydrogen Ion	Ribosomal RNA small subunit methyltransferase H	Methylation	RHEA	34755880
MMDBr0025145	di-mu-Sulfido-diiron(1+)	5'-Deoxyadenosine	Probable dual-specificity RNA methyltransferase RlmN	Methylation	RHEA	34755880
MMDBr0025193	Adenosine triphosphate	ADP	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0025216	Hydrogen Ion	NAD	NAD(P)H dehydrogenase (quinone)	Dehydrogenation; Redox reaction; Reduction	RHEA	34755880
MMDBr0025217	Hydrogen Ion	NADP(+)	NAD(P)H dehydrogenase (quinone)	Dehydrogenation; Redox reaction; Reduction	RHEA	34755880
MMDBr0025258	Adenosine triphosphate	Hydrogen Ion	tRNA-specific 2-thiouridylase MnmA	2-Thiolation of uridine	RHEA	34755880
MMDBr0025493	Adenosine triphosphate	diphosphate	Protein adenylyltransferase MntA	Reversible transfer of an adenylyl group	RHEA	34755880
MMDBr0025494	Adenosine triphosphate	diphosphate	Protein adenylyltransferase SelO	Reversible transfer of an adenylyl group	RHEA	34755880
MMDBr0025495	L-Threonine	diphosphate	Protein adenylyltransferase SelO	Reversible transfer of an adenylyl group	RHEA	34755880
MMDBr0025496	L-Threonine	diphosphate	Protein adenylyltransferase SelO	Reversible transfer of an adenylyl group	RHEA	34755880
MMDBr0025514	Acetyl-CoA	Malonyl-CoA	Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha	Carboxylation	RHEA	34755880
MMDBr0025630	S-Adenosylmethionine	Hydrogen Ion	PqqA peptide cyclase	Cycle formation	RHEA	34755880
MMDBr0025650	Hydrogen Ion	Hydrogen Ion	NADH-quinone oxidoreductase subunit C/D	Redox reaction	RHEA	34755880
MMDBr0025654	L-Serine	diphosphate	Protein adenylyltransferase SelO	Reversible transfer of an adenylyl group	RHEA	34755880
MMDBr0025655	L-Serine	diphosphate	Protein adenylyltransferase SelO	Reversible transfer of an adenylyl group	RHEA	34755880
MMDBr0025777	Hydrogen Ion	(6S)-5,6,7,8-tetrahydrofolic acid	Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO	Methylation	RHEA	34755880
MMDBr0025806	Water	Fe(II)-heme a	Heme A synthase	Synthesis	RHEA	34755880
MMDBr0025807	Water	Fe(II)-heme a	Heme A synthase	Synthesis	RHEA	34755880
MMDBr0025921	Hydrogen Ion	NAD	FMN-dependent NADH:quinone oxidoreductase	Redox reaction	RHEA	34755880
MMDBr0026014	Phosphate	Uridine 5'-diphosphate	Ribonuclease PH	RNA degradation	RHEA	34755880
MMDBr0026015	Phosphate	Uridine 5'-diphosphate	Ribonuclease PH	RNA degradation	RHEA	34755880
MMDBr0026016	Phosphate	Guanosine 3',5'-bis(diphosphate)	Ribonuclease PH	RNA degradation	RHEA	34755880
MMDBr0026017	Phosphate	Adenosine diphosphate	Ribonuclease PH	RNA degradation	RHEA	34755880
MMDBr0026022	Adenosine monophosphate	Adenosine	5'-nucleotidase SurE	Hydrolysis of nucleotide; Dephosphorylation	RHEA	34755880
MMDBr0026023	Cytidine monophosphate	Adenosine	5'-nucleotidase SurE	Hydrolysis of nucleotide; Dephosphorylation	RHEA	34755880
MMDBr0026024	Uridine 5'-monophosphate	Uridine	5'-nucleotidase SurE	Hydrolysis of nucleotide; Dephosphorylation	RHEA	34755880
MMDBr0026025	Guanosine monophosphate	Guanosine	5'-nucleotidase SurE	Hydrolysis of nucleotide; Dephosphorylation	RHEA	34755880
MMDBr0026046	Uridine 5'-diphosphate	Uridine triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026047	Uridine 5'-diphosphate	Cytidine triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026048	Guanosine 3',5'-bis(diphosphate)	Guanosine triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026085	Deoxyuridine-5'-diphosphate	Deoxyuridine triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026086	2'-Deoxycytidine 5'-diphosphate	Deoxycytidine 5'-triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026087	2'-Deoxyadenosine 5'-diphosphate	Deoxyadenosine triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026088	2'-Deoxyguanosine 5'-diphosphate	2'-Deoxyguanosine 5'-triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880

Genome Data

Genome Link

Not Available

Genome Length

Not Available

# Predicted Proteins

GenBank Sequence Modification Date

17-FEB-2022

MiMeDB Deposition Date

Reference

PMID: 17704766

Source Links

GenBank