MiMeDB: Metallosphaera sedula DSM 5348 (MMDBm0001813)

Microbe Identification

Microbe name

Metallosphaera sedula DSM 5348

NCBI Taxonomy ID

399549

Microbe Taxonomy

Superkingdom

Archaea

Kingdom

Archaea

Phylum

Crenarchaeota

Class

Thermoprotei

Order

Sulfolobales

Family

Sulfolobaceae

Genus

Metallosphaera

Species

sedula

Strain

Microbe Properties

Gram staining properties

Positive

Shape

Cocci

Mobility

Flagellar presence

Yes

Number of membranes

Oxygen preference

Aerobe

Optimal temperature

Temperature range

Thermophilic

Habitat

Specialized

Biotic relationship

Free living

Cell arrangement

Singles

Sporulation

Singles

Metabolism

Iron oxidizer

Energy source

Not Available

Host and Biospecimens

Host	Body site	Biospecimen	Details	Data Source	Reference
Human	Gut	Feces	Expected but not quantified

Health Effects

Host	Related Health Condition	Biospecimen	Microbal response/effect	Data Source	Reference

Related Metabolites

Metabolic Reactions

Reactions

Reaction ID	Precursor	Product	Enzyme	Reaction Type	Data Source	Reference
MMDBr0012860	(2R)-2-phosphoglyceric acid	Water	Enolase	Enolization	RHEA	34755880
MMDBr0012883	D-Glyceraldehyde 3-phosphate	(2R)-3-phospho-glyceroyl phosphate	Glyceraldehyde-3-phosphate dehydrogenase	Dehydrogenation	RHEA	34755880
MMDBr0012884	D-Glyceraldehyde 3-phosphate	(2R)-3-phospho-glyceroyl phosphate	Glyceraldehyde-3-phosphate dehydrogenase	Dehydrogenation	RHEA	34755880
MMDBr0012954	Adenosine triphosphate	Argininosuccinic acid	Argininosuccinate synthase	Synthesis	RHEA	34755880
MMDBr0012970	D-erythro-1-(Imidazol-4-yl)glycerol 3-phosphate	3-(Imidazol-4-yl)-2-oxopropyl phosphate	Imidazoleglycerol-phosphate dehydratase	Hydration/dehydration of C-O bond; Synthesis	RHEA	34755880
MMDBr0012971	beta-D-Fructose 1,6-bisphosphate	beta-D-Fructose 6-phosphate	Fructose-1,6-bisphosphatase/inositol-1-monophosphatase	Aldol addition (or reverse); Dephosphorylation	RHEA	34755880
MMDBr0013038	diphosphate	Phosphoribosyl pyrophosphate	Tryptophan biosynthesis protein TrpCD	Transfer of a ribosyl group	RHEA	34755880
MMDBr0013046	(6R)-5,10-methylene-5,6,7,8-tetrahydrofolic acid	(6S)-5,6,7,8-tetrahydrofolic acid	3-methyl-2-oxobutanoate hydroxymethyltransferase	Methylation	RHEA	34755880
MMDBr0013062	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin	4a-Carbinolamine tetrahydrobiopterin	Putative pterin-4-alpha-carbinolamine dehydratase	Hydration/dehydration of C-O bond	RHEA	34755880
MMDBr0013170	Adenosine monophosphate	ADP	Adenylate kinase	Phosphorylation	RHEA	34755880
MMDBr0013173	diphosphate	Phosphoribosyl pyrophosphate	Bifunctional protein PyrR	Transfer of phosphoribosyl group	RHEA	34755880
MMDBr0013194	Water	Hydroxymethylbilane	Porphobilinogen deaminase	Deamination	RHEA	34755880
MMDBr0013226	Adenosine triphosphate	ADP	Putative thymidylate kinase	Phosphorylation	RHEA	34755880
MMDBr0013295	(S)-4-Amino-5-oxopentanoate	5-Aminolevulinic acid	Glutamate-1-semialdehyde 2,1-aminomutase	Non-hydrolytic bond cleavage (or its reversal)	RHEA	34755880
MMDBr0013299	D-Glucose	Gluconolactone	Glucose 1-dehydrogenase	Dehydrogenation	RHEA	34755880
MMDBr0013309	Phosphoglycolic acid	Glycolic acid	Phosphoglycolate phosphatase	Dephosphorylation	RHEA	34755880
MMDBr0013312	D-Glucose	Gluconolactone	Glucose 1-dehydrogenase	Dehydrogenation	RHEA	34755880
MMDBr0013347	beta-D-Fructose 1,6-bisphosphate	D-Glyceraldehyde 3-phosphate	Fructose-bisphosphate aldolase	Aldol addition (or reverse)	RHEA	34755880
MMDBr0013357	(2R)-3-phosphoglyceric acid	(2R)-3-phospho-glyceroyl phosphate	Phosphoglycerate kinase	Phosphorylation	RHEA	34755880
MMDBr0013470	(2R)-2-phosphoglyceric acid	(2R)-3-phosphoglyceric acid	2,3-bisphosphoglycerate-independent phosphoglycerate mutase	Intramolecular transfer of functional group	RHEA	34755880
MMDBr0013670	Hydrogen Ion	Agmatine	Pyruvoyl-dependent arginine decarboxylase AaxB	Decarboxylation	RHEA	34755880
MMDBr0013728	(2E,6E,10E)-geranylgeranyl diphosphate	2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate	Digeranylgeranylglyceryl phosphate synthase	Synthesis	RHEA	34755880
MMDBr0013773	1-(5-phosphoribosyl)-ATP	Phosphoribosyl pyrophosphate	ATP phosphoribosyltransferase	Transfer of a ribosyl group	RHEA	34755880
MMDBr0013784	D-Glyceraldehyde 3-phosphate	Dihydroxyacetone phosphate	Bifunctional PGK/TIM	Isomerization	RHEA	34755880
MMDBr0013946	Carbamoylphosphate	Hydrogen Ion	Protein pyrABCN	Transfer of a carbamoyl group	RHEA	34755880
MMDBr0013983	Adenosine triphosphate	Adenosine monophosphate	4-hydroxybutyrate--CoA ligase 1	Ligation	RHEA	34755880
MMDBr0014061	5-O-(1-Carboxyvinyl)-3-phosphoshikimate	Chorismate	Chorismate synthase	Synthesis	RHEA	34755880
MMDBr0014068	3-Dehydroquinate	3-Dehydroshikimic acid	Catabolic 3-dehydroquinase	Hydration/dehydration of C-O bond; Synthesis	RHEA	34755880
MMDBr0014102	NAD	Dihydroxyacetone phosphate	Glycerol-1-phosphate dehydrogenase [NAD(P)+]	Dehydrogenation	RHEA	34755880
MMDBr0014103	NADP(+)	Dihydroxyacetone phosphate	Glycerol-1-phosphate dehydrogenase [NAD(P)+]	Dehydrogenation	RHEA	34755880
MMDBr0014167	(R)-2,3-Dihydroxy-isovalerate	(2S)-2-acetolactic acid	Ketol-acid reductoisomerase, mitochondrial	Isomerization	RHEA	34755880
MMDBr0014236	dCTP	Deoxyuridine triphosphate	dCTP deaminase	Deamination	RHEA	34755880
MMDBr0014256	1-(5-phosphoribosyl)-ATP	1-(5-phosphoribosyl)-5'-AMP	Phosphoribosyl-ATP pyrophosphatase	Dephosphorylation; Synthesis	RHEA	34755880
MMDBr0014296	gamma-Hydroxybutyrate	4-Hydroxybutyryl-CoA	4-hydroxybutyrate--CoA ligase 1	Ligation	RHEA	34755880
MMDBr0014299	Acetic acid	Acetyl-CoA	Acetyl-coenzyme A synthetase 1	Ligation; Synthesis	RHEA	34755880
MMDBr0014311	Isopentenyl pyrophosphate	Dimethylallylpyrophosphate	Isopentenyl-diphosphate Delta-isomerase	Isomerization	RHEA	34755880
MMDBr0014327	(2E,6E,10E)-geranylgeranyl diphosphate	diphosphate	Geranylgeranylglyceryl phosphate synthase	Synthesis	RHEA	34755880
MMDBr0014340	1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate	(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate	Indole-3-glycerol phosphate synthase	Synthesis	RHEA	34755880
MMDBr0014447	Adenosine triphosphate	ADP	UMP-CMP kinase	Phosphorylation	RHEA	34755880
MMDBr0014486	(R)-2,3-Dihydroxy-isovalerate	alpha-Ketoisovaleric acid	Dihydroxy-acid dehydratase, mitochondrial	Hydration/dehydration of C-O bond	RHEA	34755880
MMDBr0014487	(R)-2,3-Dihydroxy-isovalerate	alpha-Ketoisovaleric acid	Dihydroxy-acid dehydratase, mitochondrial	Hydration/dehydration of C-O bond	RHEA	34755880
MMDBr0014491	AICAR	Phosphoribosyl formamidocarboxamide	5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase	Synthesis	RHEA	34755880
MMDBr0014504	Cytidine triphosphate	CDP	Riboflavin kinase	Phosphorylation	RHEA	34755880
MMDBr0014619	L-3,4-Dihydroxybutan-2-one 4-phosphate	6,7-Dimethyl-8-(1-D-ribityl)lumazine	6,7-dimethyl-8-ribityllumazine synthase	Synthesis	RHEA	34755880
MMDBr0014645	Malonic semialdehyde	Hydrogen Ion	Malonyl CoA reductase (NADP)	Reduction	RHEA	34755880
MMDBr0014646	CoA	Hydrogen Ion	Succinate-semialdehyde dehydrogenase (acetylating)	Dehydrogenation	RHEA	34755880
MMDBr0014647	NADP(+)	acryloyl-CoA	Acryloyl-coenzyme A reductase	Reduction	RHEA	34755880
MMDBr0014651	3-Hydroxypropionyl-CoA	acryloyl-CoA	3-hydroxypropionyl-coenzyme A dehydratase	Hydration/dehydration of C-O bond	RHEA	34755880
MMDBr0014654	3-hydroxypropanoic acid	3-Hydroxypropionyl-CoA	3-hydroxypropionyl-coenzyme A synthetase	Synthesis	RHEA	34755880
MMDBr0014718	(R)-2,3-Dihydroxy-3-methylpentanoate	2-Keto-3-methyl-valerate	Dihydroxy-acid dehydratase, mitochondrial	Hydration/dehydration of C-O bond	RHEA	34755880
MMDBr0014719	(R)-2,3-Dihydroxy-3-methylpentanoate	2-Keto-3-methyl-valerate	Dihydroxy-acid dehydratase, mitochondrial	Hydration/dehydration of C-O bond	RHEA	34755880
MMDBr0014776	Farnesyl pyrophosphate	diphosphate	Protoheme IX farnesyltransferase, mitochondrial	Farnesylation	RHEA	34755880
MMDBr0014821	Oxalacetic acid	Hydrogen carbonate	Phosphoenolpyruvate carboxylase	Carboxylation	RHEA	34755880
MMDBr0015000	(R)-2,3-Dihydroxy-isovalerate	(2S)-2-acetolactic acid	Ketol-acid reductoisomerase (NAD(P)(+))	Isomerization	RHEA	34755880
MMDBr0017950	aldehydo-D-ribose 5-phosphate	Hydrogen Ion	Pyridoxal 5'-phosphate synthase subunit PDX1	Synthesis	RHEA	34755880
MMDBr0015136	3-Isopropylmalate	2-Isopropylmalic acid	3-isopropylmalate dehydratase large subunit gloJ	Isomerization	RHEA	34755880
MMDBr0016807	Glycine	ADP-5-ethyl-4-methylthiazole-2-carboxylate	Thiamine thiazole synthase	Synthesis	RHEA	34755880
MMDBr0016907	Adenosine triphosphate	ADP	ATP synthase subunit alpha	ATP hydrolysis; Synthesis	RHEA	34755880
MMDBr0017101	3'-dephospho-CoA	CoA	GTP-dependent dephospho-CoA kinase	Phosphorylation	RHEA	34755880
MMDBr0017874	Water	L-Glutamic acid	Thermolabile glutaminase	Synthesis	RHEA	34755880
MMDBr0017879	Adenosine triphosphate	2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine	Phosphoribosylformylglycinamidine synthase	Synthesis	RHEA	34755880
MMDBr0017882	Adenosine triphosphate	ADP	Carbamoyl-phosphate synthase small chain	Synthesis	RHEA	34755880
MMDBr0017916	5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide	AICAR	Imidazole glycerol phosphate synthase subunit HisH	Synthesis	RHEA	34755880
MMDBr0024389	Adenosine triphosphate	diphosphate	Leucine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024411	Adenosine triphosphate	Hydrogen Ion	Type-2 serine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024415	(S)-4-Amino-5-oxopentanoate	Hydrogen Ion	Glutamyl-tRNA reductase	Reduction	RHEA	34755880
MMDBr0024418	Adenosine triphosphate	diphosphate	Alanine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024449	Adenosine triphosphate	diphosphate	Methionine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024474	Adenosine triphosphate	diphosphate	Proline--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024483	Water	Hydrogen Ion	Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C	Amide group addition	RHEA	34755880
MMDBr0024559	Adenosine triphosphate	Hydrogen Ion	Histidine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024568	Water	Hydrogen Ion	Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C	Amide group addition	RHEA	34755880
MMDBr0024578	Adenosine triphosphate	diphosphate	Cysteine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024590	Adenosine triphosphate	ADP	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0024628	Adenosine triphosphate	Hydrogen Ion	Phenylalanine--tRNA ligase beta subunit	Ligation	RHEA	34755880
MMDBr0024650	Hydrogen Ion	di-mu-Sulfido-diiron(2+)	Ferredoxin--NADP reductase	Dehydrogenation; Reduction	RHEA	34755880
MMDBr0024745	L-Glutamic acid	diphosphate	Glutamate--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024759	Adenosine triphosphate	diphosphate	RNA 3'-terminal phosphate cyclase	Cycle formation	RHEA	34755880
MMDBr0024774	Hydrogen Ion	Carbon dioxide	Probable glycine dehydrogenase (decarboxylating) subunit 1	Dehydrogenation	RHEA	34755880
MMDBr0024787	Adenosine triphosphate	Hydrogen Ion	Threonine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024905	Spermidine	1,3-Diaminopropane	Probable deoxyhypusine synthase	Synthesis	RHEA	34755880
MMDBr0024956	S-Adenosylmethionine	Hydrogen Ion	Diphthine synthase	Synthesis	RHEA	34755880
MMDBr0024971	L-Threonylcarbamoyladenylate	Hydrogen Ion	tRNA N6-adenosine threonylcarbamoyltransferase	Synthesis	RHEA	34755880
MMDBr0025030	Adenosine triphosphate	ADP	Putative [LysW]-aminoadipate/[LysW]-glutamate kinase	Phosphorylation	RHEA	34755880
MMDBr0025060	Adenosine triphosphate	Hydrogen Ion	Type-2 serine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0025114	S-Adenosylmethionine	Hydrogen Ion	tRNA (cytidine(56)-2'-O)-methyltransferase	Methylation	RHEA	34755880
MMDBr0025124	S-Adenosylmethionine	Hydrogen Ion	tRNA (guanine(26)-N(2))-dimethyltransferase	Methylation	RHEA	34755880
MMDBr0025193	Adenosine triphosphate	ADP	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0025294	Adenosine triphosphate	diphosphate	4-hydroxybutyrate--CoA ligase 2	Ligation	RHEA	34755880
MMDBr0025326	Guanosine triphosphate	Hydrogen Ion	Probable GTP 3',8-cyclase	Cycle formation	RHEA	34755880
MMDBr0025423	Adenosine triphosphate	ADP	Putative [LysW]-aminoadipate/[LysW]-glutamate kinase	Phosphorylation	RHEA	34755880
MMDBr0026046	Uridine 5'-diphosphate	Uridine triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026047	Uridine 5'-diphosphate	Cytidine triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026048	Guanosine 3',5'-bis(diphosphate)	Guanosine triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026061	Cytidine triphosphate	Uridine 5'-diphosphate	Nucleoside-triphosphatase THEP1	Dephosphorylation	RHEA	34755880
MMDBr0026062	Uridine triphosphate	Uridine 5'-diphosphate	Nucleoside-triphosphatase THEP1	Dephosphorylation	RHEA	34755880
MMDBr0026063	Adenosine triphosphate	Adenosine diphosphate	Nucleoside-triphosphatase THEP1	Dephosphorylation	RHEA	34755880
MMDBr0026064	Guanosine triphosphate	Guanosine 3',5'-bis(diphosphate)	Nucleoside-triphosphatase THEP1	Dephosphorylation	RHEA	34755880
MMDBr0026085	Deoxyuridine-5'-diphosphate	Deoxyuridine triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026086	2'-Deoxycytidine 5'-diphosphate	Deoxycytidine 5'-triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026087	2'-Deoxyadenosine 5'-diphosphate	Deoxyadenosine triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026088	2'-Deoxyguanosine 5'-diphosphate	2'-Deoxyguanosine 5'-triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880

Genome Data

Genome Link

Not Available

Genome Length

Not Available

# Predicted Proteins

GenBank Sequence Modification Date

17-FEB-2022

MiMeDB Deposition Date

Reference

PMID: 17704766

Source Links

GenBank