MiMeDB: Legionella pneumophila subsp. pneumophila str. Philadelphia 1 (MMDBm0001769)

Microbe Identification

Microbe name

Legionella pneumophila subsp. pneumophila str. Philadelphia 1

NCBI Taxonomy ID

272624

Microbe Taxonomy

Superkingdom

Bacteria

Kingdom

Eubacteria

Phylum

Proteobacteria

Class

Gammaproteobacteria

Order

Legionellales

Family

Legionellaceae

Genus

Legionella

Species

pneumophila

Strain

Microbe Properties

Gram staining properties

Positive

Shape

Bacilli

Mobility

Yes

Flagellar presence

Yes

Number of membranes

Oxygen preference

Aerobe

Optimal temperature

Not Available

Temperature range

Mesophilic

Habitat

HostAssociated

Biotic relationship

Free living

Cell arrangement

Singles

Sporulation

Singles

Metabolism

Not Available

Energy source

Chemoorganotroph

Host and Biospecimens

Host	Body site	Biospecimen	Details	Data Source	Reference
Human			Unknown

Health Effects

Host	Related Health Condition	Biospecimen	Microbal response/effect	Data Source	Reference

Related Metabolites

Metabolic Reactions

Reactions

Reaction ID	Precursor	Product	Enzyme	Reaction Type	Data Source	Reference
MMDBr0012860	(2R)-2-phosphoglyceric acid	Water	Enolase	Enolization	RHEA	34755880
MMDBr0012876	Deoxyuridine triphosphate	diphosphate	Probable deoxyuridine 5'-triphosphate nucleotidohydrolase	Dephosphorylation; Hydrolysis of bond	RHEA	34755880
MMDBr0012888	Citric acid	D-threo-Isocitric acid	Aconitate hydratase A	Hydration/dehydration of C-O bond	RHEA	34755880
MMDBr0012895	diphosphate	Phosphoribosyl pyrophosphate	Orotate phosphoribosyltransferase	Transfer of a ribosyl group	RHEA	34755880
MMDBr0012946	Water	Hydrogen Ion	N-succinylglutamate 5-semialdehyde dehydrogenase	Dehydrogenation	RHEA	34755880
MMDBr0012953	(R)-Pantoate	Pantothenic acid	Pantothenate synthetase	Ligation; Phosphorylation; Synthesis	RHEA	34755880
MMDBr0012954	Adenosine triphosphate	Argininosuccinic acid	Argininosuccinate synthase	Synthesis	RHEA	34755880
MMDBr0012970	D-erythro-1-(Imidazol-4-yl)glycerol 3-phosphate	3-(Imidazol-4-yl)-2-oxopropyl phosphate	Imidazoleglycerol-phosphate dehydratase	Hydration/dehydration of C-O bond; Synthesis	RHEA	34755880
MMDBr0012975	NAD	Dihydroxyacetone phosphate	Glycerol-3-phosphate dehydrogenase [NAD(+)]	Dehydrogenation	RHEA	34755880
MMDBr0012976	NADP(+)	Dihydroxyacetone phosphate	Glycerol-3-phosphate dehydrogenase [NAD(P)+]	Dehydrogenation	RHEA	34755880
MMDBr0012989	Adenosine triphosphate	ADP	D-alanine--D-alanine ligase	Ligation	RHEA	34755880
MMDBr0013026	Hydrogen Ion	Carbon dioxide	Orotidine 5'-phosphate decarboxylase	Decarboxylation	RHEA	34755880
MMDBr0013038	diphosphate	Phosphoribosyl pyrophosphate	Tryptophan biosynthesis protein TrpCD	Transfer of a ribosyl group	RHEA	34755880
MMDBr0013045	Alpha-D-glucose 6-phosphate	beta-D-Fructose 6-phosphate	Glucose-6-phosphate isomerase	Isomerization	RHEA	34755880
MMDBr0013046	(6R)-5,10-methylene-5,6,7,8-tetrahydrofolic acid	(6S)-5,6,7,8-tetrahydrofolic acid	3-methyl-2-oxobutanoate hydroxymethyltransferase	Methylation	RHEA	34755880
MMDBr0013062	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin	4a-Carbinolamine tetrahydrobiopterin	Putative pterin-4-alpha-carbinolamine dehydratase	Hydration/dehydration of C-O bond	RHEA	34755880
MMDBr0013081	(6R)-5,10-methylene-5,6,7,8-tetrahydrofolic acid	7,8-dihydrofolate monoglutamate	Bifunctional dihydrofolate reductase-thymidylate synthase	Reduction; Synthesis	RHEA	34755880
MMDBr0013098	NADP(+)	Hydrogen Ion	UDP-N-acetylenolpyruvoylglucosamine reductase	Reduction	RHEA	34755880
MMDBr0013173	diphosphate	Phosphoribosyl pyrophosphate	Bifunctional protein PyrR	Transfer of phosphoribosyl group	RHEA	34755880
MMDBr0013179	Adenosine triphosphate	ADP	Replicase large subunit	Synthesis of a primer	RHEA	34755880
MMDBr0013187	Adenosine triphosphate	Shikimate 3-phosphate	Pentafunctional AROM polypeptide	Phosphorylation	RHEA	34755880
MMDBr0013194	Water	Hydroxymethylbilane	Porphobilinogen deaminase	Deamination	RHEA	34755880
MMDBr0013224	Hydrogen Ion	diphosphate	Bifunctional protein GlmU	N-Acetylation; Phosphorylation; Isomerization	RHEA	34755880
MMDBr0013226	Adenosine triphosphate	ADP	Putative thymidylate kinase	Phosphorylation	RHEA	34755880
MMDBr0013248	Acetyl-CoA	CoA	Bifunctional protein GlmU	N-Acetylation	RHEA	34755880
MMDBr0013280	D-Arabinose 5-phosphate	3-deoxy-alpha-D-manno-2-octulosonate-8-phosphate	2-dehydro-3-deoxyphosphooctonate aldolase	Aldol addition (or reverse)	RHEA	34755880
MMDBr0013295	(S)-4-Amino-5-oxopentanoate	5-Aminolevulinic acid	Glutamate-1-semialdehyde 2,1-aminomutase	Non-hydrolytic bond cleavage (or its reversal)	RHEA	34755880
MMDBr0013303	alpha-Ketoglutarate	3-Phosphonatooxypyruvate(3-)	Phosphoserine aminotransferase	Amine group addition	RHEA	34755880
MMDBr0013316	Water	L-Histidinol	Histidine biosynthesis bifunctional protein HisB	Dephosphorylation	RHEA	34755880
MMDBr0013339	aldehydo-D-ribose 5-phosphate	D-Ribulose 5-phosphate	Bifunctional ribokinase/ribose-5-phosphate isomerase A	Isomerization	RHEA	34755880
MMDBr0013357	(2R)-3-phosphoglyceric acid	(2R)-3-phospho-glyceroyl phosphate	Phosphoglycerate kinase	Phosphorylation	RHEA	34755880
MMDBr0013395	Oxygen	Hydrogen peroxide	Probable pyridoxamine 5'-phosphate oxidase	Oxidation	RHEA	34755880
MMDBr0013408	1-Deoxy-D-xylulose 5-phosphate	Hydrogen Ion	Pyridoxine 5'-phosphate synthase	Synthesis	RHEA	34755880
MMDBr0013422	LL-2,6-Diaminoheptanedioate	Meso-2,6-Diaminoheptanedioate	Diaminopimelate epimerase	Epimerization; Racemization	RHEA	34755880
MMDBr0013426	Homogentisic acid	Maleylacetoacetic acid	Homogentisate 1,2-dioxygenase	Oxygenation	RHEA	34755880
MMDBr0013431	1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide	5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase	Isomerization	RHEA	34755880
MMDBr0013458	Guanosine triphosphate	Guanosine diphosphate	Adenylosuccinate synthetase	Synthesis	RHEA	34755880
MMDBr0013464	(7R,8S)-7,8-diammoniononanoic acid	Dethiobiotin	Biotin biosynthesis bifunctional protein BioCD	Amine group addition; Synthesis	RHEA	34755880
MMDBr0013466	Water	Hydrogen peroxide	Probable pyridoxamine 5'-phosphate oxidase	Oxidation	RHEA	34755880
MMDBr0013470	(2R)-2-phosphoglyceric acid	(2R)-3-phosphoglyceric acid	2,3-bisphosphoglycerate-independent phosphoglycerate mutase	Intramolecular transfer of functional group	RHEA	34755880
MMDBr0013488	Phosphate	2-deoxy-alpha-D-ribose 1-phosphate	Pyrimidine-nucleoside phosphorylase	Phosphorylation	RHEA	34755880
MMDBr0013503	3-(4-hydroxyphenyl)pyruvic acid	Carbon dioxide	4-hydroxyphenylpyruvate dioxygenase	Oxygenation	RHEA	34755880
MMDBr0013526	Pantothenic acid	(R)-4'-phosphopantothenic acid	Bifunctional enzyme BirA/CoaX	Phosphorylation	RHEA	34755880
MMDBr0013529	Adenosine triphosphate	ADP	UDP-N-acetylmuramoylalanine--D-glutamate ligase	Ligation	RHEA	34755880
MMDBr0013544	alpha-Ketoglutarate	(R)-3-hydroxy-2-oxo-4-phosphooxybutanoic acid	Phosphoserine aminotransferase	Amine group addition	RHEA	34755880
MMDBr0013547	Adenosine triphosphate	ADP	CTP synthase	Synthesis	RHEA	34755880
MMDBr0013578	Adenylsuccinic acid	Adenosine monophosphate	Adenylosuccinate lyase	Non-hydrolytic bond cleavage (or its reversal)	RHEA	34755880
MMDBr0013579	Adenylsuccinic acid	Adenosine monophosphate	Adenylosuccinate lyase	Non-hydrolytic bond cleavage (or its reversal)	RHEA	34755880
MMDBr0013642	(S)-2,3,4,5-tetrahydrodipicolinate	(S)-2-succinylamino-6-oxoheptanedioic acid	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	Transfer of succinyl moiety	RHEA	34755880
MMDBr0013681	NADP(+)	3-Dehydroshikimic acid	Pentafunctional AROM polypeptide	Dehydrogenation	RHEA	34755880
MMDBr0013704	(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylic acid	2-methyl-cis-aconitic acid	Aconitate hydratase A	Hydration/dehydration of C-O bond	RHEA	34755880
MMDBr0013715	Agmatine	N-Carbamoylputrescine	Putative agmatine deiminase	Hydrolysis	RHEA	34755880
MMDBr0013742	3'-dephospho-CoA	ADP	Dephospho-CoA kinase CAB5	Phosphorylation	RHEA	34755880
MMDBr0013745	Coproporphyrinogen III	Carbon dioxide	Oxygen-dependent coproporphyrinogen-III oxidase	Oxidation	RHEA	34755880
MMDBr0013755	D-Ribose-5-phosphate	Water	Pseudouridine-5'-phosphate glycosidase	Transfer of a glycosyl group	RHEA	34755880
MMDBr0013784	D-Glyceraldehyde 3-phosphate	Dihydroxyacetone phosphate	Bifunctional PGK/TIM	Isomerization	RHEA	34755880
MMDBr0013785	Sphinganine 1-phosphate	Palmitaldehyde	Probable sphingosine-1-phosphate lyase	Non-hydrolytic bond cleavage (or its reversal)	RHEA	34755880
MMDBr0013792	Adenosine triphosphate	ADP	NAD kinase	Phosphorylation	RHEA	34755880
MMDBr0013801	Phosphoenolpyruvic acid	Phosphate	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	Synthesis	RHEA	34755880
MMDBr0013809	Ribose-1-phosphate	D-Ribose-5-phosphate	Phosphopentomutase	Transfers of a phosphate group; Isomerization; Intramolecular transfer of functional group	RHEA	34755880
MMDBr0013811	4-Phospho-D-erythronate	(R)-3-hydroxy-2-oxo-4-phosphooxybutanoic acid	Erythronate-4-phosphate dehydrogenase	Dehydrogenation	RHEA	34755880
MMDBr0013843	Adenosine triphosphate	ADP	Thymidine kinase	Phosphorylation	RHEA	34755880
MMDBr0013851	Adenosine triphosphate	ADP	Cytochrome c biogenesis ATP-binding export protein CcmA	Transport	RHEA	34755880
MMDBr0013884	Hydrogen Ion	beta-Alanine	L-aspartate decarboxylase dtxS4	Decarboxylation	RHEA	34755880
MMDBr0013892	Hydrogen Ion	Carbon dioxide	N-succinylarginine dihydrolase	Hydrolysis	RHEA	34755880
MMDBr0013895	L-Glutamic-gamma-semialdehyde	Hydrogen Ion	Gamma-glutamyl phosphate reductase	Reduction	RHEA	34755880
MMDBr0013908	Guanosine triphosphate	Guanosine diphosphate	GTPase ArgK	Dephosphorylation; Hydrolysis; Nucleic acid synthesis and/or repair	RHEA	34755880
MMDBr0013921	(R)-4'-phosphopantetheine	3'-dephospho-CoA	Phosphopantetheine adenylyltransferase	Dephosphorylation	RHEA	34755880
MMDBr0013929	Hydrogen Ion	Carbon dioxide	Uroporphyrinogen decarboxylase	Decarboxylation	RHEA	34755880
MMDBr0013946	Carbamoylphosphate	Hydrogen Ion	Protein pyrABCN	Transfer of a carbamoyl group	RHEA	34755880
MMDBr0013970	L-Alanine	D-Alanine	L-alanine/L-glutamate racemase	Racemization	RHEA	34755880
MMDBr0013978	Hydrogen peroxide	Water	Bromoperoxidase-catalase	Synthesis	RHEA	34755880
MMDBr0014021	Hydrogen Ion	Hydrogen peroxide	Methanobactin mb-OB3b	Dismutation	RHEA	34755880
MMDBr0014035	Adenosine triphosphate	ADP	Guanylate kinase	Phosphorylation	RHEA	34755880
MMDBr0014061	5-O-(1-Carboxyvinyl)-3-phosphoshikimate	Chorismate	Chorismate synthase	Synthesis	RHEA	34755880
MMDBr0014068	3-Dehydroquinate	3-Dehydroshikimic acid	Catabolic 3-dehydroquinase	Hydration/dehydration of C-O bond; Synthesis	RHEA	34755880
MMDBr0014083	Shikimate 3-phosphate	5-O-(1-Carboxyvinyl)-3-phosphoshikimate	Pentafunctional AROM polypeptide	Synthesis; Dehydration and isomerisation; Oxidation; Phosphorylation; Transfer of a carboxyvinyl group	RHEA	34755880
MMDBr0014105	(S)-malate(2-)	Hydrogen Ion	Malate dehydrogenase	Dehydrogenation	RHEA	34755880
MMDBr0014114	N-(5-Phospho-D-ribosyl)anthranilate	1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate	Phosphoribosyl isomerase A	Isomerization	RHEA	34755880
MMDBr0014160	3-deoxy-D-arabino-heptulosonate-7-phosphate	3-Dehydroquinate	Pentafunctional AROM polypeptide	Phosphorylation; Synthesis	RHEA	34755880
MMDBr0014217	Water	Formamide	Formimidoylglutamase	Hydrolysis of carbon-nitrogen bond	RHEA	34755880
MMDBr0014221	Hydrogen Ion	Fe2+	Deferrochelatase/peroxidase EfeB	Chelation	RHEA	34755880
MMDBr0014225	Water	LL-2,6-Diaminoheptanedioate	Succinyl-diaminopimelate desuccinylase	Hydrolysis of carbon-nitrogen bond	RHEA	34755880
MMDBr0014236	dCTP	Deoxyuridine triphosphate	dCTP deaminase	Deamination	RHEA	34755880
MMDBr0014251	(6R)-5,10-methylene-5,6,7,8-tetrahydrofolic acid	5,10-Methenyltetrahydrofolate	C-1-tetrahydrofolate synthase, cytoplasmic	Synthesis	RHEA	34755880
MMDBr0014257	Adenosine triphosphate	Nicotinic acid adenine dinucleotide	Probable nicotinate-nucleotide adenylyltransferase	Reversible transfer of an adenylyl group	RHEA	34755880
MMDBr0014311	Isopentenyl pyrophosphate	Dimethylallylpyrophosphate	Isopentenyl-diphosphate Delta-isomerase	Isomerization	RHEA	34755880
MMDBr0014323	Adenosine triphosphate	ADP	Bifunctional enzyme MurC/Ddl	Ligation	RHEA	34755880
MMDBr0014333	alpha-D-Glucosamine 1-phosphate	D-glucosamine 6-phosphate	Phosphoglucosamine mutase	Intramolecular transfer of functional group	RHEA	34755880
MMDBr0014337	3-deoxy-D-manno-2-octulosonate	CMP-3-deoxy-beta-D-manno-octulosonate	3-deoxy-manno-octulosonate cytidylyltransferase	Transfer of a cytidylyl group	RHEA	34755880
MMDBr0014340	1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate	(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate	Indole-3-glycerol phosphate synthase	Synthesis	RHEA	34755880
MMDBr0014365	4-Imidazolone-5-propionic acid	Formiminoglutamic acid	Imidazolonepropionase	Non-hydrolytic bond cleavage (or its reversal)	RHEA	34755880
MMDBr0014369	5,10-Methenyltetrahydrofolate	(6S)-10-formyltetrahydrofolic acid	C-1-tetrahydrofolate synthase, cytoplasmic	Reversible cyclization	RHEA	34755880
MMDBr0014377	alpha-Ketoglutarate	3-(Imidazol-4-yl)-2-oxopropyl phosphate	Histidinol-phosphate aminotransferase	Amine group addition	RHEA	34755880
MMDBr0014394	(2S)-2-[5-Amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinic acid	AICAR	Adenylosuccinate lyase	Non-hydrolytic bond cleavage (or its reversal)	RHEA	34755880
MMDBr0014395	(2S)-2-[5-Amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinic acid	AICAR	Adenylosuccinate lyase	Non-hydrolytic bond cleavage (or its reversal)	RHEA	34755880
MMDBr0014407	Argininosuccinic acid	fumarate	Bifunctional protein ArgHA	Non-hydrolytic bond cleavage (or its reversal)	RHEA	34755880
MMDBr0014431	Water	ADP	Bis(5'-nucleosyl)-tetraphosphatase, symmetrical	Dephosphorylation; Hydrolysis of bond	RHEA	34755880
MMDBr0014447	Adenosine triphosphate	ADP	UMP-CMP kinase	Phosphorylation	RHEA	34755880
MMDBr0014502	1,6-Anhydro-N-acetyl-beta-muramate	ADP	Anhydro-N-acetylmuramic acid kinase	Phosphorylation	RHEA	34755880
MMDBr0014581	Adenosine triphosphate	ADP	Probable copper-transporting ATPase PacS	ATP hydrolysis	RHEA	34755880
MMDBr0017926	Adenosine triphosphate	ADP	CTP synthase	Synthesis	RHEA	34755880
MMDBr0014696	Farnesyl pyrophosphate	di-trans,octa-cis-undecaprenyl diphosphate	Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)	Synthesis	RHEA	34755880
MMDBr0014732	4-Hydroxybenzoic acid	3-Octaprenyl-4-hydroxybenzoate	4-hydroxybenzoate octaprenyltransferase	Synthesis; Reverse C-prenylation of phenalenone	RHEA	34755880
MMDBr0014763	7-Deaza-7-carboxyguanine	7-Cyano-7-carbaguanine	7-cyano-7-deazaguanine synthase	Synthesis	RHEA	34755880
MMDBr0014776	Farnesyl pyrophosphate	diphosphate	Protoheme IX farnesyltransferase, mitochondrial	Farnesylation	RHEA	34755880
MMDBr0014816	2'-Deoxyinosine triphosphate	DIMP	Inosine triphosphate pyrophosphatase	Dephosphorylation	RHEA	34755880
MMDBr0014825	di-trans,octa-cis-undecaprenyl phosphate	di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine	Phospho-N-acetylmuramoyl-pentapeptide-transferase	Transfer of phospho-N-acetylmuramoyl-pentapeptide	RHEA	34755880
MMDBr0014848	Water	diphosphate	Inosine triphosphate pyrophosphatase	Dephosphorylation	RHEA	34755880
MMDBr0014909	Water	diphosphate	Inosine triphosphate pyrophosphatase	Dephosphorylation	RHEA	34755880
MMDBr0014935	Adenosine triphosphate	ADP	Methionine import ATP-binding protein MetN	Transport	RHEA	34755880
MMDBr0017943	Adenosine triphosphate	ADP	Methionine import ATP-binding protein MetN	Transport	RHEA	34755880
MMDBr0015026	di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine	di-trans-octa-cis-undecaprenyl diphospho-[N-acetyl-alpha-D-glucosaminyl-(1->4)]-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine	UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase	UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase 1; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase 2; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase 3	RHEA	34755880
MMDBr0015120	(6R)-NADHX	(6S)-NADHX	Bifunctional NAD(P)H-hydrate repair enzyme Nnr	Epimerization	RHEA	34755880
MMDBr0015125	(6R)-NADPHX	(6S)-NADPHX	Bifunctional NAD(P)H-hydrate repair enzyme Nnr	Epimerization	RHEA	34755880
MMDBr0015316	L-Aspartate-semialdehyde	(2S,4S)-4-Hydroxy-2,3,4,5-tetrahydrodipicolinate	4-hydroxy-tetrahydrodipicolinate synthase	Synthesis	RHEA	34755880
MMDBr0015350	Water	2,4-diacetamido-2,4,6-trideoxy-alpha-D-mannopyranose	GDP/UDP-N,N'-diacetylbacillosamine 2-epimerase (hydrolyzing)	Epimerization	RHEA	34755880
MMDBr0015352	2,4-diacetamido-2,4,6-trideoxy-alpha-D-mannopyranose	N,N-diacetyllegionaminate	N,N'-diacetyllegionaminic acid synthase	Synthesis	RHEA	34755880
MMDBr0015369	Cytidine triphosphate	CMP-N,N-diacetyllegionaminate	CMP-N,N'-diacetyllegionaminic acid synthase	Synthesis	RHEA	34755880
MMDBr0015402	(S)-2,3,4,5-tetrahydrodipicolinate	(2S,4S)-4-Hydroxy-2,3,4,5-tetrahydrodipicolinate	4-hydroxy-tetrahydrodipicolinate reductase	Reduction	RHEA	34755880
MMDBr0015405	(S)-2,3,4,5-tetrahydrodipicolinate	(2S,4S)-4-Hydroxy-2,3,4,5-tetrahydrodipicolinate	4-hydroxy-tetrahydrodipicolinate reductase	Reduction	RHEA	34755880
MMDBr0016813	2-Aminobenzoic acid	2-(4-dimethylaminophenyl)diazenylbenzoic acid	FMN-dependent NADPH-azoreductase	Reduction	RHEA	34755880
MMDBr0016907	Adenosine triphosphate	ADP	ATP synthase subunit alpha	ATP hydrolysis; Synthesis	RHEA	34755880
MMDBr0017834	(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate	D-Glyceraldehyde 3-phosphate	Tryptophan synthase	Synthesis	RHEA	34755880
MMDBr0017843	Adenosine triphosphate	Adenosine monophosphate	GMP synthase [glutamine-hydrolyzing]	Synthesis	RHEA	34755880
MMDBr0017850	L-Threonine	L-2-Amino-3-oxobutanoic acid	L-threonine 3-dehydrogenase	Dehydrogenation	RHEA	34755880
MMDBr0017851	Fructose 6-phosphate	D-glucosamine 6-phosphate	Glutamine--fructose-6-phosphate aminotransferase [isomerizing]	Amine group addition	RHEA	34755880
MMDBr0017852	Adenosine triphosphate	ADP	Glutamate--cysteine ligase EgtA	Ligation	RHEA	34755880
MMDBr0017871	(6R)-5,10-methylene-5,6,7,8-tetrahydrofolic acid	(6S)-5,6,7,8-tetrahydrofolic acid	Serine hydroxymethyltransferase	Methylation	RHEA	34755880
MMDBr0017874	Water	L-Glutamic acid	Thermolabile glutaminase	Synthesis	RHEA	34755880
MMDBr0017894	Water	Hydrogen Ion	Histidinol dehydrogenase	Dehydrogenation	RHEA	34755880
MMDBr0017897	Adenosine triphosphate	diphosphate	S-adenosylmethionine synthase	Synthesis	RHEA	34755880
MMDBr0017903	L-Histidine	Ammonium	Histidine ammonia-lyase	Non-hydrolytic bond cleavage (or its reversal)	RHEA	34755880
MMDBr0017916	5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide	AICAR	Imidazole glycerol phosphate synthase subunit HisH	Synthesis	RHEA	34755880
MMDBr0024345	Adenosine triphosphate	Hydrogen Ion	Tyrosine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024360	Adenosine triphosphate	diphosphate	Valine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024368	Adenosine triphosphate	diphosphate	Isoleucine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024389	Adenosine triphosphate	diphosphate	Leucine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024411	Adenosine triphosphate	Hydrogen Ion	Type-2 serine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024415	(S)-4-Amino-5-oxopentanoate	Hydrogen Ion	Glutamyl-tRNA reductase	Reduction	RHEA	34755880
MMDBr0024418	Adenosine triphosphate	diphosphate	Alanine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024449	Adenosine triphosphate	diphosphate	Methionine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024459	Uridine triphosphate	diphosphate	Bifunctional uridylyltransferase/uridylyl-removing enzyme	Transfer of an uridylyl group	RHEA	34755880
MMDBr0024474	Adenosine triphosphate	diphosphate	Proline--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024477	Adenosine triphosphate	diphosphate	CCA-adding enzyme	Synthesis and repair of 3'-terminal CCA sequence of tRNA	RHEA	34755880
MMDBr0024483	Water	Hydrogen Ion	Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C	Amide group addition	RHEA	34755880
MMDBr0024485	Choline	Hydrogen Ion	Phosphatidylcholine synthase	Synthesis	RHEA	34755880
MMDBr0024539	Hydrogen Ion	5'-Deoxyadenosine	Lipoyl synthase	Synthesis	RHEA	34755880
MMDBr0024548	(6S)-5,6,7,8-tetrahydrofolic acid	(6R)-5,10-methylene-5,6,7,8-tetrahydrofolic acid	Probable aminomethyltransferase	Methylation	RHEA	34755880
MMDBr0024552	S-Adenosylmethionine	S-Adenosylhomocysteine	Malonyl-[acyl-carrier protein] O-methyltransferase	Methylation	RHEA	34755880
MMDBr0024559	Adenosine triphosphate	Hydrogen Ion	Histidine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024568	Water	Hydrogen Ion	Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C	Amide group addition	RHEA	34755880
MMDBr0024578	Adenosine triphosphate	diphosphate	Cysteine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024590	Adenosine triphosphate	ADP	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0024597	L-Aspartic acid	diphosphate	Aspartate--tRNA(Asp/Asn) ligase	Ligation	RHEA	34755880
MMDBr0024616	NAD	Hydrogen Ion	Type VI secretion system spike protein VgrG1	Transfer of a ribosyl group	RHEA	34755880
MMDBr0024628	Adenosine triphosphate	Hydrogen Ion	Phenylalanine--tRNA ligase beta subunit	Ligation	RHEA	34755880
MMDBr0024629	S-Adenosylmethionine	Hydrogen Ion	tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC	Synthesis	RHEA	34755880
MMDBr0024630	S-Adenosylmethionine	Hydrogen Ion	Ribosomal RNA small subunit methyltransferase A	Methylation	RHEA	34755880
MMDBr0024656	Adenosine triphosphate	diphosphate	Arginine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024666	Adenosine triphosphate	diphosphate	Lysine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024707	di-mu-Sulfido-diiron(1+)	5'-Deoxyadenosine	Biotin synthase	Synthesis	RHEA	34755880
MMDBr0024745	L-Glutamic acid	diphosphate	Glutamate--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024751	lipid II(3−)	Hydrogen Ion	Penicillin-binding protein 2a	Glycan chain elongation	RHEA	34755880
MMDBr0024774	Hydrogen Ion	Carbon dioxide	Probable glycine dehydrogenase (decarboxylating) subunit 1	Dehydrogenation	RHEA	34755880
MMDBr0024778	(6S)-10-formyltetrahydrofolic acid	Hydrogen Ion	Methionyl-tRNA formyltransferase	Transfer of a formyl group	RHEA	34755880
MMDBr0024787	Adenosine triphosphate	Hydrogen Ion	Threonine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024813	Dimethylallylpyrophosphate	diphosphate	tRNA dimethylallyltransferase	Transfer of a dimethylallyl group	RHEA	34755880
MMDBr0024826	2-deoxy-alpha-D-ribose 1-phosphate	Deoxyribose 5-phosphate	Phosphopentomutase	Transfers of a phosphate group; Isomerization; Intramolecular transfer of functional group	RHEA	34755880
MMDBr0024834	S-Adenosylmethionine	Hydrogen Ion	Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE	Methylation	RHEA	34755880
MMDBr0024851	L-Dihydroorotic acid	orotate	Dihydroorotate dehydrogenase (quinone)	Dehydrogenation	RHEA	34755880
MMDBr0024883	S-Adenosylmethionine	Hydrogen Ion	S-adenosylmethionine:tRNA ribosyltransferase-isomerase	Isomerization	RHEA	34755880
MMDBr0024925	Glycerol 3-phosphate	Phosphate	Glycerol-3-phosphate acyltransferase	Acylation	RHEA	34755880
MMDBr0024967	S-Adenosylmethionine	Hydrogen Ion	tRNA (guanine(37)-N1)-methyltransferase Trm5b	Methylation	RHEA	34755880
MMDBr0024971	L-Threonylcarbamoyladenylate	Hydrogen Ion	tRNA N6-adenosine threonylcarbamoyltransferase	Synthesis	RHEA	34755880
MMDBr0024974	S-Adenosylmethionine	Hydrogen Ion	tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase	Synthesis	RHEA	34755880
MMDBr0024977	S-Adenosylmethionine	Hydrogen Ion	Ribosomal protein S12 methylthiotransferase RimO	Methylthiolation	RHEA	34755880
MMDBr0025060	Adenosine triphosphate	Hydrogen Ion	Type-2 serine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0025066	S-Adenosylmethionine	Hydrogen Ion	Demethylmenaquinone methyltransferase	Methylation	RHEA	34755880
MMDBr0025071	S-Adenosylmethionine	S-Adenosylhomocysteine	tRNA (guanine-N(7)-)-methyltransferase	Methylation	RHEA	34755880
MMDBr0025075	S-Adenosylmethionine	Hydrogen Ion	Ribosomal RNA large subunit methyltransferase E	Methylation	RHEA	34755880
MMDBr0025078	S-Adenosylmethionine	S-Adenosylhomocysteine	Ribosomal RNA small subunit methyltransferase G	Methylation	RHEA	34755880
MMDBr0025081	S-Adenosylmethionine	Hydrogen Ion	Ribosomal RNA large subunit methyltransferase K/L	Methylation	RHEA	34755880
MMDBr0025085	S-Adenosylmethionine	Hydrogen Ion	Putative ribosomal RNA large subunit methyltransferase H	Methylation	RHEA	34755880
MMDBr0025100	S-Adenosylmethionine	Hydrogen Ion	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	Methylation	RHEA	34755880
MMDBr0025102	di-mu-Sulfido-diiron(1+)	5'-Deoxyadenosine	Ribosomal RNA large subunit methyltransferase N	Methylation	RHEA	34755880
MMDBr0025105	S-Adenosylmethionine	Hydrogen Ion	Ribosomal RNA small subunit methyltransferase H	Methylation	RHEA	34755880
MMDBr0025144	S-Adenosylmethionine	Hydrogen Ion	Ribosomal RNA small subunit methyltransferase J	Methylation	RHEA	34755880
MMDBr0025145	di-mu-Sulfido-diiron(1+)	5'-Deoxyadenosine	Probable dual-specificity RNA methyltransferase RlmN	Methylation	RHEA	34755880
MMDBr0025167	Adenosine triphosphate	Hydrogen Ion	tRNA(Ile)-lysidine synthase	Synthesis	RHEA	34755880
MMDBr0025171	S-Adenosylmethionine	Hydrogen Ion	Ribosomal RNA large subunit methyltransferase K/L	Methylation	RHEA	34755880
MMDBr0025193	Adenosine triphosphate	ADP	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0025215	ADP	Hydrogen Ion	Putative phosphoenolpyruvate synthase regulatory protein	Synthesis	RHEA	34755880
MMDBr0025248	lipid A (E. coli)	hepta-acyl lipid A	Lipid A palmitoyltransferase PagP	Transfer of a fatty acid residue	RHEA	34755880
MMDBr0025249	(2-N,3-O-bis(3-Hydroxytetradecanoyl)-4-O-phosphono-beta-D-glucosaminyl)-(1->6)-(2-N,3-O-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl phosphate)	Lipid IVb	Lipid A palmitoyltransferase PagP	Transfer of a fatty acid residue	RHEA	34755880
MMDBr0025250	Lipid IIA	lipid IIB	Lipid A palmitoyltransferase PagP	Transfer of a fatty acid residue	RHEA	34755880
MMDBr0025258	Adenosine triphosphate	Hydrogen Ion	tRNA-specific 2-thiouridylase MnmA	2-Thiolation of uridine	RHEA	34755880
MMDBr0025300	Hydrogen Ion	diphosphate	Putative phosphoenolpyruvate synthase regulatory protein	Synthesis	RHEA	34755880
MMDBr0025490	S-Adenosylmethionine	Hydrogen Ion	Ribosomal protein L11 methyltransferase	Methylation	RHEA	34755880
MMDBr0025493	Adenosine triphosphate	diphosphate	Protein adenylyltransferase MntA	Reversible transfer of an adenylyl group	RHEA	34755880
MMDBr0025495	L-Threonine	diphosphate	Protein adenylyltransferase SelO	Reversible transfer of an adenylyl group	RHEA	34755880
MMDBr0025497	Guanosine triphosphate	diphosphate	Multifunctional virulence effector protein DrrA	Not Available	RHEA	34755880
MMDBr0025514	Acetyl-CoA	Malonyl-CoA	Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha	Carboxylation	RHEA	34755880
MMDBr0025584	L-Serine	Hydrogen Ion	Phosphocholine transferase AnkX	Transfer of phosphocholine	RHEA	34755880
MMDBr0025620	L-Cysteine	Hydrogen Ion	Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase	Transfer of the diacylglyceryl group	RHEA	34755880
MMDBr0025638	Adenosine triphosphate	Hydrogen Ion	tRNA-cytidine(32) 2-sulfurtransferase	Sulfuration	RHEA	34755880
MMDBr0025639	Adenosine triphosphate	Hydrogen Ion	tRNA-cytidine(32) 2-sulfurtransferase	Sulfuration	RHEA	34755880
MMDBr0025650	Hydrogen Ion	Hydrogen Ion	NADH-quinone oxidoreductase subunit C/D	Redox reaction	RHEA	34755880
MMDBr0025714	L-Glutamic acid	Hydrogen Ion	Calmodulin-dependent glutamylase SidJ	Not Available	RHEA	34755880
MMDBr0025715	L-Glutamic acid	Hydrogen Ion	Calmodulin-dependent glutamylase SidJ	Not Available	RHEA	34755880
MMDBr0025918	Water	Hydrogen Ion	4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase	Synthesis	RHEA	34755880
MMDBr0025919	Water	Hydrogen Ion	4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase	Synthesis	RHEA	34755880
MMDBr0025921	Hydrogen Ion	NAD	FMN-dependent NADH:quinone oxidoreductase	Redox reaction	RHEA	34755880
MMDBr0026014	Phosphate	Uridine 5'-diphosphate	Ribonuclease PH	RNA degradation	RHEA	34755880
MMDBr0026015	Phosphate	Uridine 5'-diphosphate	Ribonuclease PH	RNA degradation	RHEA	34755880
MMDBr0026016	Phosphate	Guanosine 3',5'-bis(diphosphate)	Ribonuclease PH	RNA degradation	RHEA	34755880
MMDBr0026017	Phosphate	Adenosine diphosphate	Ribonuclease PH	RNA degradation	RHEA	34755880
MMDBr0026022	Adenosine monophosphate	Adenosine	5'-nucleotidase SurE	Hydrolysis of nucleotide; Dephosphorylation	RHEA	34755880
MMDBr0026023	Cytidine monophosphate	Adenosine	5'-nucleotidase SurE	Hydrolysis of nucleotide; Dephosphorylation	RHEA	34755880
MMDBr0026024	Uridine 5'-monophosphate	Uridine	5'-nucleotidase SurE	Hydrolysis of nucleotide; Dephosphorylation	RHEA	34755880
MMDBr0026025	Guanosine monophosphate	Guanosine	5'-nucleotidase SurE	Hydrolysis of nucleotide; Dephosphorylation	RHEA	34755880
MMDBr0026046	Uridine 5'-diphosphate	Uridine triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026047	Uridine 5'-diphosphate	Cytidine triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026048	Guanosine 3',5'-bis(diphosphate)	Guanosine triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026065	Cytidine triphosphate	Cytidine monophosphate	Nucleoside triphosphate pyrophosphatase	Purine metabolism and pyrimidine metabolism; Hydrolysis of pyrophosphate; Dephosphorylation	RHEA	34755880
MMDBr0026066	Uridine triphosphate	Uridine 5'-monophosphate	Nucleoside triphosphate pyrophosphatase	Purine metabolism and pyrimidine metabolism; Hydrolysis of pyrophosphate; Dephosphorylation	RHEA	34755880
MMDBr0026067	Adenosine triphosphate	Adenosine monophosphate	Nucleoside triphosphate pyrophosphatase	Purine metabolism and pyrimidine metabolism; Hydrolysis of pyrophosphate; Dephosphorylation	RHEA	34755880
MMDBr0026068	Guanosine triphosphate	Guanosine monophosphate	Nucleoside triphosphate pyrophosphatase	Purine metabolism and pyrimidine metabolism; Hydrolysis of pyrophosphate; Dephosphorylation	RHEA	34755880
MMDBr0026085	Deoxyuridine-5'-diphosphate	Deoxyuridine triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026086	2'-Deoxycytidine 5'-diphosphate	Deoxycytidine 5'-triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026087	2'-Deoxyadenosine 5'-diphosphate	Deoxyadenosine triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026088	2'-Deoxyguanosine 5'-diphosphate	2'-Deoxyguanosine 5'-triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026089	Deoxyuridine triphosphate	2'-Deoxyuridine 5'-phosphate	Nucleoside triphosphate pyrophosphatase	Purine metabolism and pyrimidine metabolism; Hydrolysis of pyrophosphate; Dephosphorylation	RHEA	34755880
MMDBr0026090	Deoxycytidine 5'-triphosphate	2'-Deoxycytidine 5'-phosphate	Nucleoside triphosphate pyrophosphatase	Purine metabolism and pyrimidine metabolism; Hydrolysis of pyrophosphate; Dephosphorylation	RHEA	34755880
MMDBr0026091	Deoxyadenosine triphosphate	Deoxyadenosine monophosphate	Nucleoside triphosphate pyrophosphatase	Purine metabolism and pyrimidine metabolism; Hydrolysis of pyrophosphate; Dephosphorylation	RHEA	34755880
MMDBr0026092	2'-Deoxyguanosine 5'-triphosphate	2'-Deoxyguanosine 5'-monophosphate	Nucleoside triphosphate pyrophosphatase	Purine metabolism and pyrimidine metabolism; Hydrolysis of pyrophosphate; Dephosphorylation	RHEA	34755880

Genome Data

Genome Link

Not Available

Genome Length

Not Available

# Predicted Proteins

GenBank Sequence Modification Date

17-FEB-2022

MiMeDB Deposition Date

Reference

PMID: 17704766

Source Links

GenBank