MiMeDB: Methylobacterium nodulans ORS 2060 (MMDBm0001861)

Microbe Identification

Microbe name

Methylobacterium nodulans ORS 2060

NCBI Taxonomy ID

460265

Microbe Taxonomy

Superkingdom

Bacteria

Kingdom

Eubacteria

Phylum

Proteobacteria

Class

Alphaproteobacteria

Order

Rhizobiales

Family

Methylobacteriaceae

Genus

Methylobacterium

Species

nodulans

Strain

Microbe Properties

Gram staining properties

Positive

Shape

Bacilli

Mobility

Flagellar presence

Yes

Number of membranes

Oxygen preference

Aerobe

Optimal temperature

Not Available

Temperature range

Mesophilic

Habitat

HostAssociated

Biotic relationship

Free living

Cell arrangement

Pairs - Singles

Sporulation

Pairs - Singles

Metabolism

Nitrogen fixation

Energy source

Methylotroph

Host and Biospecimens

Host	Body site	Biospecimen	Details	Data Source	Reference
Human	Gut	Feces	Expected but not quantified

Health Effects

Host	Related Health Condition	Biospecimen	Microbal response/effect	Data Source	Reference

Related Metabolites

Metabolic Reactions

Reactions

Reaction ID	Precursor	Product	Enzyme	Reaction Type	Data Source	Reference
MMDBr0012895	Orotidylic acid	Phosphoribosyl pyrophosphate	Orotate phosphoribosyltransferase	Transfer of a ribosyl group	RHEA	34755880
MMDBr0013026	Orotidylic acid	Uridine 5'-monophosphate	Orotidine 5'-phosphate decarboxylase	Decarboxylation	RHEA	34755880
MMDBr0013038	N-(5-Phospho-D-ribosyl)anthranilate	Phosphoribosyl pyrophosphate	Tryptophan biosynthesis protein TrpCD	Transfer of a ribosyl group	RHEA	34755880
MMDBr0013081	(6R)-5,10-methylene-5,6,7,8-tetrahydrofolic acid	7,8-dihydrofolate monoglutamate	Bifunctional dihydrofolate reductase-thymidylate synthase	Reduction; Synthesis	RHEA	34755880
MMDBr0013186	4-Imidazolone-5-propionic acid	Trans-urocanate	Urocanate hydratase	Hydration/dehydration of C-O bond	RHEA	34755880
MMDBr0013221	(R)-2,3-Dihydroxy-3-methylpentanoate	(S)-2-ethyl-2-hydroxy-3-oxobutanoic acid	Ketol-acid reductoisomerase, mitochondrial	Isomerization	RHEA	34755880
MMDBr0013274	L-Homoserine	O-Phosphohomoserine	Homoserine kinase	Phosphorylation	RHEA	34755880
MMDBr0013333	N-Acetylglutamic acid	N-Acetyl-L-glutamyl 5-phosphate	Protein ARG5,6, mitochondrial	Phosphorylation	RHEA	34755880
MMDBr0013376	S-Adenosylmethionine	(E)-3-(Methoxycarbonyl)pent-2-enedioate	Trans-aconitate 2-methyltransferase	Methylation	RHEA	34755880
MMDBr0013422	LL-2,6-Diaminoheptanedioate	Meso-2,6-Diaminoheptanedioate	Diaminopimelate epimerase	Epimerization; Racemization	RHEA	34755880
MMDBr0013431	1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide	5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase	Isomerization	RHEA	34755880
MMDBr0013458	Guanosine triphosphate	Guanosine diphosphate	Adenylosuccinate synthetase	Synthesis	RHEA	34755880
MMDBr0013464	(7R,8S)-7,8-diammoniononanoic acid	Dethiobiotin	Biotin biosynthesis bifunctional protein BioCD	Amine group addition; Synthesis	RHEA	34755880
MMDBr0013547	Uridine triphosphate	Cytidine triphosphate	CTP synthase	Synthesis	RHEA	34755880
MMDBr0013588	1-aminocyclopropane-1-carboxylic acid	2-oxobutanoic acid	1-aminocyclopropane-1-carboxylate deaminase	Deamination	RHEA	34755880
MMDBr0013642	(S)-2,3,4,5-tetrahydrodipicolinate	(S)-2-succinylamino-6-oxoheptanedioic acid	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	Transfer of succinyl moiety	RHEA	34755880
MMDBr0013755	D-Ribose-5-phosphate	Pseudouridine 5'-phosphate	Pseudouridine-5'-phosphate glycosidase	Transfer of a glycosyl group	RHEA	34755880
MMDBr0013790	Oxalacetic acid	Phosphoenolpyruvic acid	Phosphoenolpyruvate carboxykinase (ATP)	Phosphorylation	RHEA	34755880
MMDBr0013801	Phosphoenolpyruvic acid	UDP-N-Acetyl-3-(1-carboxyvinyl)-D-glucosamine	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	Synthesis	RHEA	34755880
MMDBr0013809	Ribose-1-phosphate	D-Ribose-5-phosphate	Phosphopentomutase	Transfers of a phosphate group; Isomerization; Intramolecular transfer of functional group	RHEA	34755880
MMDBr0013833	5,10-Methenyl-5,6,7,8-tetrahydromethanopterin	N(5)-formyl-5,6,7,8-tetrahydromethanopterin	Methenyltetrahydromethanopterin cyclohydrolase	Hydrolysis	RHEA	34755880
MMDBr0013884	L-Aspartic acid	beta-Alanine	L-aspartate decarboxylase dtxS4	Decarboxylation	RHEA	34755880
MMDBr0013895	L-Glutamic-gamma-semialdehyde	gamma-L-Glutamyl 5-phosphate	Gamma-glutamyl phosphate reductase	Reduction	RHEA	34755880
MMDBr0013908	Guanosine triphosphate	Guanosine diphosphate	GTPase ArgK	Dephosphorylation; Hydrolysis; Nucleic acid synthesis and/or repair	RHEA	34755880
MMDBr0013921	(R)-4'-phosphopantetheine	3'-dephospho-CoA	Phosphopantetheine adenylyltransferase	Dephosphorylation	RHEA	34755880
MMDBr0013941	S-Methyl-5-thio-alpha-D-ribose 1-phosphate	5-Methylthioribulose 1-phosphate	5-deoxyribose 1-phosphate isomerase	Isomerization	RHEA	34755880
MMDBr0013966	(6S)-5,6,7,8-tetrahydrofolic acid	(6S)-10-formyltetrahydrofolic acid	C-1-tetrahydrofolate synthase, cytoplasmic	Ligation; Synthesis	RHEA	34755880
MMDBr0013970	L-Alanine	D-Alanine	L-alanine/L-glutamate racemase	Racemization	RHEA	34755880
MMDBr0014061	5-O-(1-Carboxyvinyl)-3-phosphoshikimate	Chorismate	Chorismate synthase	Synthesis	RHEA	34755880
MMDBr0014105	(S)-malate(2-)	Oxalacetic acid	Malate dehydrogenase	Dehydrogenation	RHEA	34755880
MMDBr0014111	alpha-Ketoisovaleric acid	2-Isopropylmalic acid	Isopropyl malate synthase AMT7	Synthesis	RHEA	34755880
MMDBr0014126	Glycerol	Glycerol 3-phosphate	Glycerol kinase	Phosphorylation	RHEA	34755880
MMDBr0014135	S-Adenosylhomocysteine	Deoxyadenosine	Adenosylhomocysteinase	Reversible hydrolysis	RHEA	34755880
MMDBr0014167	(R)-2,3-Dihydroxy-isovalerate	(2S)-2-acetolactic acid	Ketol-acid reductoisomerase, mitochondrial	Isomerization	RHEA	34755880
MMDBr0014225	N-succinyl-(2S,6S)-2,6-diaminoheptanedioic acid	LL-2,6-Diaminoheptanedioate	Succinyl-diaminopimelate desuccinylase	Hydrolysis of carbon-nitrogen bond	RHEA	34755880
MMDBr0014256	1-(5-phosphoribosyl)-ATP	1-(5-phosphoribosyl)-5'-AMP	Phosphoribosyl-ATP pyrophosphatase	Dephosphorylation; Synthesis	RHEA	34755880
MMDBr0014282	2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine	5-Aminoimidazole ribonucleotide	Bifunctional purine biosynthetic protein ADE5,7	Ligation	RHEA	34755880
MMDBr0014323	L-Alanine	UDP-N-acetyl-alpha-D-muramoyl-L-alanine	Bifunctional enzyme MurC/Ddl	Ligation	RHEA	34755880
MMDBr0014333	alpha-D-Glucosamine 1-phosphate	D-glucosamine 6-phosphate	Phosphoglucosamine mutase	Intramolecular transfer of functional group	RHEA	34755880
MMDBr0014337	3-deoxy-D-manno-2-octulosonate	CMP-3-deoxy-beta-D-manno-octulosonate	3-deoxy-manno-octulosonate cytidylyltransferase	Transfer of a cytidylyl group	RHEA	34755880
MMDBr0014365	4-Imidazolone-5-propionic acid	Formiminoglutamic acid	Imidazolonepropionase	Non-hydrolytic bond cleavage (or its reversal)	RHEA	34755880
MMDBr0014367	Adenine	Hypoxanthine	Adenine deaminase	Deamination	RHEA	34755880
MMDBr0014377	alpha-Ketoglutarate	3-(Imidazol-4-yl)-2-oxopropyl phosphate	Histidinol-phosphate aminotransferase	Amine group addition	RHEA	34755880
MMDBr0014407	Argininosuccinic acid	fumarate	Bifunctional protein ArgHA	Non-hydrolytic bond cleavage (or its reversal)	RHEA	34755880
MMDBr0014502	1,6-Anhydro-N-acetyl-beta-muramate	N-acetyl-D-muramate 6-phosphate	Anhydro-N-acetylmuramic acid kinase	Phosphorylation	RHEA	34755880
MMDBr0014619	L-3,4-Dihydroxybutan-2-one 4-phosphate	6,7-Dimethyl-8-(1-D-ribityl)lumazine	6,7-dimethyl-8-ribityllumazine synthase	Synthesis	RHEA	34755880
MMDBr0017926	L-Glutamine	Cytidine triphosphate	CTP synthase	Synthesis	RHEA	34755880
MMDBr0014776	Farnesyl pyrophosphate	Fe(II)-heme o	Protoheme IX farnesyltransferase, mitochondrial	Farnesylation	RHEA	34755880
MMDBr0014825	di-trans,octa-cis-undecaprenyl phosphate	di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine	Phospho-N-acetylmuramoyl-pentapeptide-transferase	Transfer of phospho-N-acetylmuramoyl-pentapeptide	RHEA	34755880
MMDBr0015026	di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine	di-trans-octa-cis-undecaprenyl diphospho-[N-acetyl-alpha-D-glucosaminyl-(1->4)]-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine	UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase	UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase 1; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase 2; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase 3	RHEA	34755880
MMDBr0016462	(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate	Cyclic pyranopterin monophosphate	Cyclic pyranopterin monophosphate synthase	Synthesis	RHEA	34755880
MMDBr0016813	2-Aminobenzoic acid	2-(4-dimethylaminophenyl)diazenylbenzoic acid	FMN-dependent NADPH-azoreductase	Reduction	RHEA	34755880
MMDBr0017834	(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate	D-Glyceraldehyde 3-phosphate	Tryptophan synthase	Synthesis	RHEA	34755880
MMDBr0017874	L-Glutamine	L-Glutamic acid	Thermolabile glutaminase	Synthesis	RHEA	34755880
MMDBr0017897	L-Methionine	S-Adenosylmethionine	S-adenosylmethionine synthase	Synthesis	RHEA	34755880
MMDBr0017903	L-Histidine	Trans-urocanate	Histidine ammonia-lyase	Non-hydrolytic bond cleavage (or its reversal)	RHEA	34755880
MMDBr0017916	5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide	AICAR	Imidazole glycerol phosphate synthase subunit HisH	Synthesis	RHEA	34755880
MMDBr0024401	L-Serine	Adenosine 3',5'-diphosphate	Holo-[acyl-carrier-protein] synthase	Dehydrogenation; Synthesis	RHEA	34755880
MMDBr0024411	L-Serine	Hydrogen Ion	Type-2 serine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024471	L-Methionine	L-Cysteine	Peptide methionine sulfoxide reductase MsrA	Reduction	RHEA	34755880
MMDBr0024474	L-Proline	diphosphate	Proline--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024483	L-Glutamine	L-Glutamic acid	Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C	Amide group addition	RHEA	34755880
MMDBr0024522	Glycine	diphosphate	Glycine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024539	Tetra-mu3-sulfido-tetrairon(2+)	5'-Deoxyadenosine	Lipoyl synthase	Synthesis	RHEA	34755880
MMDBr0024568	L-Glutamine	L-Glutamic acid	Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C	Amide group addition	RHEA	34755880
MMDBr0024590	Adenosine triphosphate	ADP	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0024597	L-Aspartic acid	diphosphate	Aspartate--tRNA(Asp/Asn) ligase	Ligation	RHEA	34755880
MMDBr0024628	L-Phenylalanine	Hydrogen Ion	Phenylalanine--tRNA ligase beta subunit	Ligation	RHEA	34755880
MMDBr0024644	L-Cystine	L-Cysteine	Peptide methionine sulfoxide reductase MsrA	Reduction	RHEA	34755880
MMDBr0024656	L-Arginine	diphosphate	Arginine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024686	Nitrogen	Hydrogen	Nitrogenase iron protein	Nitrogen fixation	RHEA	34755880
MMDBr0024707	di-mu-Sulfido-diiron(1+)	5'-Deoxyadenosine	Biotin synthase	Synthesis	RHEA	34755880
MMDBr0024778	(6S)-10-formyltetrahydrofolic acid	(6S)-5,6,7,8-tetrahydrofolic acid	Methionyl-tRNA formyltransferase	Transfer of a formyl group	RHEA	34755880
MMDBr0024808	1-Deoxy-D-xylulose 5-phosphate	2-[(2R,5Z)-2-Carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate	Thiazole synthase	Synthesis	RHEA	34755880
MMDBr0024813	Dimethylallylpyrophosphate	diphosphate	tRNA dimethylallyltransferase	Transfer of a dimethylallyl group	RHEA	34755880
MMDBr0024826	2-deoxy-alpha-D-ribose 1-phosphate	Deoxyribose 5-phosphate	Phosphopentomutase	Transfers of a phosphate group; Isomerization; Intramolecular transfer of functional group	RHEA	34755880
MMDBr0024834	S-Adenosylmethionine	S-Adenosylhomocysteine	Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE	Methylation	RHEA	34755880
MMDBr0024851	L-Dihydroorotic acid	orotate	Dihydroorotate dehydrogenase (quinone)	Dehydrogenation	RHEA	34755880
MMDBr0024875	S-Adenosylmethionine	S-Adenosylhomocysteine	Ubiquinone biosynthesis O-methyltransferase	Methylation	RHEA	34755880
MMDBr0024971	L-Threonylcarbamoyladenylate	Hydrogen Ion	tRNA N6-adenosine threonylcarbamoyltransferase	Synthesis	RHEA	34755880
MMDBr0025050	L-Alanine	(S)-8-amino-7-oxononanoic acid	Putative 8-amino-7-oxononanoate synthase	Ligation; Synthesis	RHEA	34755880
MMDBr0025060	L-Serine	Hydrogen Ion	Type-2 serine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0025066	S-Adenosylmethionine	S-Adenosylhomocysteine	Demethylmenaquinone methyltransferase	Methylation	RHEA	34755880
MMDBr0025078	S-Adenosylmethionine	S-Adenosylhomocysteine	Ribosomal RNA small subunit methyltransferase G	Methylation	RHEA	34755880
MMDBr0025085	S-Adenosylmethionine	S-Adenosylhomocysteine	Putative ribosomal RNA large subunit methyltransferase H	Methylation	RHEA	34755880
MMDBr0025105	S-Adenosylmethionine	S-Adenosylhomocysteine	Ribosomal RNA small subunit methyltransferase H	Methylation	RHEA	34755880
MMDBr0025167	L-Lysine	Hydrogen Ion	tRNA(Ile)-lysidine synthase	Synthesis	RHEA	34755880
MMDBr0025190	S-Adenosylmethionine	S-Adenosylhomocysteine	Ubiquinone biosynthesis O-methyltransferase	Methylation	RHEA	34755880
MMDBr0025193	Adenosine triphosphate	ADP	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0025258	Uridine 5'-monophosphate	L-Cysteine	tRNA-specific 2-thiouridylase MnmA	2-Thiolation of uridine	RHEA	34755880
MMDBr0025514	Acetyl-CoA	Malonyl-CoA	Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha	Carboxylation	RHEA	34755880
MMDBr0025630	S-Adenosylmethionine	5'-Deoxyadenosine	PqqA peptide cyclase	Cycle formation	RHEA	34755880
MMDBr0025650	Hydrogen Ion	Hydrogen Ion	NADH-quinone oxidoreductase subunit C/D	Redox reaction	RHEA	34755880
MMDBr0025806	Fe(II)-heme o	Fe(II)-heme a	Heme A synthase	Synthesis	RHEA	34755880
MMDBr0025807	Fe(II)-heme o	Fe(II)-heme a	Heme A synthase	Synthesis	RHEA	34755880
MMDBr0025921	Hydrogen Ion	NAD	FMN-dependent NADH:quinone oxidoreductase	Redox reaction	RHEA	34755880
MMDBr0026014	Phosphate	Uridine 5'-diphosphate	Ribonuclease PH	RNA degradation	RHEA	34755880
MMDBr0026015	Phosphate	Uridine 5'-diphosphate	Ribonuclease PH	RNA degradation	RHEA	34755880
MMDBr0026016	Phosphate	Guanosine 3',5'-bis(diphosphate)	Ribonuclease PH	RNA degradation	RHEA	34755880
MMDBr0026017	Phosphate	Adenosine diphosphate	Ribonuclease PH	RNA degradation	RHEA	34755880
MMDBr0026022	Adenosine monophosphate	Adenosine	5'-nucleotidase SurE	Hydrolysis of nucleotide; Dephosphorylation	RHEA	34755880
MMDBr0026023	Cytidine monophosphate	Adenosine	5'-nucleotidase SurE	Hydrolysis of nucleotide; Dephosphorylation	RHEA	34755880
MMDBr0026024	Uridine 5'-monophosphate	Uridine	5'-nucleotidase SurE	Hydrolysis of nucleotide; Dephosphorylation	RHEA	34755880
MMDBr0026025	Guanosine monophosphate	Guanosine	5'-nucleotidase SurE	Hydrolysis of nucleotide; Dephosphorylation	RHEA	34755880
MMDBr0026046	Uridine 5'-diphosphate	Uridine triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026047	Uridine 5'-diphosphate	Cytidine triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026048	Guanosine 3',5'-bis(diphosphate)	Guanosine triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026085	Deoxyuridine-5'-diphosphate	Deoxyuridine triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026086	2'-Deoxycytidine 5'-diphosphate	Deoxycytidine 5'-triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026087	2'-Deoxyadenosine 5'-diphosphate	Deoxyadenosine triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026088	2'-Deoxyguanosine 5'-diphosphate	2'-Deoxyguanosine 5'-triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880

Genome Data

Genome Link

Not Available

Genome Length

Not Available

# Predicted Proteins

GenBank Sequence Modification Date

17-FEB-2022

MiMeDB Deposition Date

Reference

PMID: 17704766

Source Links

GenBank